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Microbial biotechnology, ISSN 1751-7915, 2016, Volume 9, Issue 3, pp. 355 - 368
...) in the yeast Pichia pastoris; this membrane protein is responsible for the synthesis of rabies neutralizing antibodies... 
HETEROLOGOUS PROTEIN EXPRESSION | YEAST | SYSTEM | SECRETORY EXPRESSION | OVEREXPRESSION | BIOTECHNOLOGY & APPLIED MICROBIOLOGY | GENE DOSAGE | PHYSIOLOGICAL-RESPONSE | MICROBIOLOGY | ENDOPLASMIC-RETICULUM | STRESS | INSULIN PRECURSOR | Metabolic Engineering | Glycoproteins - metabolism | Antigens, Viral - genetics | Neutralization Tests | Recombinant Proteins - biosynthesis | Antibodies, Neutralizing - immunology | Pichia - metabolism | Codon | Viral Envelope Proteins - metabolism | Antigens, Viral - biosynthesis | Glycoproteins - genetics | Recombinant Proteins - metabolism | Gene Expression | Viral Envelope Proteins - genetics | Viral Envelope Proteins - biosynthesis | Gene Dosage | Recombinant Proteins - genetics | Unfolded Protein Response | Protein Folding | Glycoproteins - biosynthesis | Antigens, Viral - immunology | Glycoproteins - immunology | Recombinant Proteins - immunology | Pichia - genetics | Viral Envelope Proteins - immunology | Pichia - growth & development | Yeasts | Baking yeast | Yeast | Copy number | Secretion | Antibodies | Viruses | Glycoproteins | Gene expression | Optimization | Membrane proteins | Proteins | Protein folding | Rabies | Neutralizing | Protein expression | Acid phosphatase | Folding | Viral Envelope Proteins/genetics | Viral Envelope Proteins/immunology | Glycoproteins/immunology | Antigens, Viral/biosynthesis | Recombinant Proteins/immunology | Pichia/growth & development | Antigens, Viral/genetics | Recombinant Proteins/metabolism | Life Sciences | Viral Envelope Proteins/metabolism | Viral Envelope Proteins/biosynthesis | Glycoproteins/biosynthesis | Antibodies, Neutralizing/immunology | Antigens, Viral/immunology | Glycoproteins/metabolism | Recombinant Proteins/biosynthesis | Recombinant Proteins/genetics | Pichia/genetics | Glycoproteins/genetics | Pichia/metabolism
Journal Article
Nature (London), ISSN 1476-4687, 2014, Volume 514, Issue 7523, pp. 455 - 461
The human immunodeficiency virus type 1 (HIV-1) envelope (Env) spike, comprising three gp120 and three gp41 subunits, is a conformational machine... 
ENVELOPE GLYCOPROTEIN TRIMERS | B-CELL RESPONSES | POTENT NEUTRALIZATION | NEUTRALIZING ANTIBODY | CRYSTAL-STRUCTURE | MULTIDISCIPLINARY SCIENCES | IMMUNODEFICIENCY-VIRUS TYPE-1 | INFLUENZA-VIRUS | CORE STRUCTURE | DEPENDENT EPITOPE | EBOLA-VIRUS | HIV Envelope Protein gp120 - genetics | HIV Envelope Protein gp41 - genetics | Protein Subunits - immunology | HIV Envelope Protein gp41 - immunology | Humans | Protein Multimerization | AIDS Vaccines - immunology | Molecular Sequence Data | Crystallography, X-Ray | HIV Envelope Protein gp41 - chemistry | Virus Internalization | Genetic Variation | HIV Envelope Protein gp120 - immunology | HIV Infections - immunology | Antibodies, Neutralizing - immunology | HIV Antibodies - immunology | Protein Structure, Quaternary | Polysaccharides - chemistry | HIV Envelope Protein gp120 - chemistry | Protein Subunits - genetics | Amino Acid Sequence | Membrane Fusion | Models, Molecular | Glycosylation | Polysaccharides - immunology | AIDS Vaccines - chemistry | Immune Evasion | Protein Subunits - chemistry | Structural Homology, Protein | Cohort Studies | Physiological aspects | HIV antibodies | Viral proteins | Structure | Health aspects | Infections | Immunology | Peptides | Human immunodeficiency virus--HIV | Crystals | X-ray crystallography | HIV infections | Protein function predictions | Protein vaccines | BASIC BIOLOGICAL SCIENCES | 60 APPLIED LIFE SCIENCES
Journal Article
Journal of Virology, ISSN 0022-538X, 03/2014, Volume 88, Issue 5, pp. 2633 - 2644
Classifications Services JVI Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley Reddit... 
HTLV-III | VIROLOGY | GP120 INNER DOMAIN | TRANSMEMBRANE GLYCOPROTEIN | EFFECTOR FUNCTION | IMMUNODEFICIENCY-VIRUS TYPE-1 | VPU PROTEIN | CONFORMATIONAL TRANSITIONS | VACCINE EFFICACY TRIAL | AIDS PATIENTS | DISEASE PROGRESSION | env Gene Products, Human Immunodeficiency Virus - immunology | Human Immunodeficiency Virus Proteins - immunology | Humans | Protein Multimerization | Antibody-Dependent Cell Cytotoxicity - immunology | env Gene Products, Human Immunodeficiency Virus - metabolism | CD4-Positive T-Lymphocytes - immunology | HIV Infections - immunology | HIV Antibodies - immunology | nef Gene Products, Human Immunodeficiency Virus - metabolism | Protein Interaction Domains and Motifs | Epitopes, T-Lymphocyte - immunology | CD4-Positive T-Lymphocytes - virology | env Gene Products, Human Immunodeficiency Virus - chemistry | HIV Antibodies - metabolism | CD4 Antigens - immunology | Cell Line | Viral Regulatory and Accessory Proteins - immunology | Models, Molecular | Protein Binding - immunology | Viral Regulatory and Accessory Proteins - metabolism | Human Immunodeficiency Virus Proteins - metabolism | HIV-1 - immunology | CD4 Antigens - chemistry | nef Gene Products, Human Immunodeficiency Virus - immunology | Protein Conformation | Epitopes, T-Lymphocyte - metabolism | CD4 Antigens - metabolism | HIV Infections - metabolism | Pathogenesis and Immunity
Journal Article
Nature communications, ISSN 2041-1723, 2018, Volume 9, Issue 1, pp. 3067 - 17
Current efforts to develop Zika virus (ZIKV) subunit vaccines have been focused on premembrane (prM) and envelope (E... 
PROTECTIVE IMMUNITY | NONSTRUCTURAL PROTEIN NS1 | DNA VACCINE | ENCEPHALITIS-VIRUS | MULTIDISCIPLINARY SCIENCES | WEST-NILE-VIRUS | CROSS-REACTIVITY | CANDIDATE VACCINE | VESICULAR STOMATITIS-VIRUS | DENGUE VIRUS | SEXUAL TRANSMISSION | Antigens, Viral - metabolism | Zika Virus - genetics | Vaccination | Viral Vaccines - genetics | Vaccines, DNA - immunology | Polyproteins - immunology | Vesiculovirus - immunology | Antigens, Viral - genetics | Male | Antibodies, Neutralizing - immunology | Th17 Cells - metabolism | Female | Zika Virus Infection - prevention & control | Zika Virus - metabolism | Disease Models, Animal | Viral Nonstructural Proteins - immunology | Zika Virus - immunology | Viral Envelope Proteins - genetics | Cytokines - metabolism | Genetic Vectors - immunology | Viral Nonstructural Proteins - genetics | Polyproteins - genetics | Th2 Cells - metabolism | Antigens, Viral - immunology | Animals | Vaccines, Attenuated | Vaccines, Synthetic | Zika Virus Infection - immunology | Antibodies, Viral - immunology | Viral Envelope Proteins - immunology | Viral Nonstructural Proteins - metabolism | Mice | Mice, Inbred BALB C | Viral Vaccines - immunology | Vector-borne diseases | Immunization | Immune response | Helper cells | Antibodies | Viruses | Zika virus | Lymphocytes T | Infections | Vaccines | Proteins | Stomatitis | Lymphocytes | Attenuation | Immune system
Journal Article
Science (American Association for the Advancement of Science), ISSN 1095-9203, 2013, Volume 342, Issue 6165, pp. 1477 - 1483
Journal Article
PLoS pathogens, ISSN 1553-7366, 02/2017, Volume 13, Issue 2, p. e1006178
Journal Article
Journal Article
Proceedings of the National Academy of Sciences - PNAS, ISSN 1091-6490, 2010, Volume 107, Issue 31, pp. 13800 - 13805
The envelope spike of HIV is one of the most highly N-glycosylated structures found in nature... 
Polysaccharides | HIV | Vaccination | Cell lines | Antibodies | Viruses | Glycoproteins | Trimers | Epitopes | HIV 1 | 2G12 | gp120 | Glycosylation | Vaccine | NEUTRALIZING ANTIBODIES | MASS-SPECTROMETRIC CHARACTERIZATION | TYPE-1 ANTIBODY 2G12 | MULTIDISCIPLINARY SCIENCES | N-GLYCANS | glycosylation | LINKED OLIGOSACCHARIDES | VIRUS TYPE-1 | HIV-1 GP120 | vaccine | DC-SIGN | VACCINE DESIGN | GLYCOPROTEIN GP120 | Antigens, Viral - metabolism | Membrane Glycoproteins - metabolism | Humans | Membrane Glycoproteins - chemistry | Virion - chemistry | HIV Envelope Protein gp120 - metabolism | Simian Immunodeficiency Virus - chemistry | HIV Envelope Protein gp120 - immunology | HIV-1 - chemistry | Oligosaccharides - chemistry | Viral Envelope Proteins - metabolism | Polysaccharides - chemistry | Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization | HIV Envelope Protein gp120 - chemistry | Membrane Glycoproteins - immunology | Simian Immunodeficiency Virus - immunology | Virion - immunology | Cell Line | HIV-1 - metabolism | Antigens, Viral - chemistry | Polysaccharides - immunology | Oligosaccharides - metabolism | Virion - metabolism | Polysaccharides - metabolism | Antigens, Viral - immunology | HIV-1 - immunology | Oligosaccharides - immunology | Viral Envelope Proteins - chemistry | Golgi Apparatus - metabolism | Viral Envelope Proteins - immunology | Simian Immunodeficiency Virus - metabolism | Kinetics | Antigens | Immunological deficiency syndromes | Genetic aspects | Health aspects | Enzymes | Immunodeficiency | Vaccines | Monomers | Infection | Envelopes | N-linked glycans | Acquired immune deficiency syndrome | Virions | Glycoprotein gp120 | Biological Sciences
Journal Article