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PLoS pathogens, ISSN 1553-7374, 11/2013, Volume 9, Issue 11, pp. e1003773 - e1003773
... with the mitochondrial adaptor protein MAVS (also known as IPS-1, CARDIF and VISA) and initiates a signalling cascade that culminates in the activation of the transcriptional... 
Parasitology | Life Sciences & Biomedicine | Microbiology | Science & Technology | Virology | Epithelial Cells - metabolism | Influenza A virus - genetics | Respiratory Mucosa - virology | Interferon Regulatory Factor-7 - genetics | Interferon Type I - immunology | Interferon Regulatory Factor-3 - genetics | Interleukins - metabolism | Orthomyxoviridae Infections - genetics | Respiratory Mucosa - pathology | Interleukins - genetics | Interleukins - immunology | Respiratory Mucosa - immunology | Adaptor Proteins, Signal Transducing - immunology | Interferon Type I - metabolism | Influenza A virus - immunology | Membrane Proteins - metabolism | Interferon Regulatory Factor-3 - immunology | Nerve Tissue Proteins - immunology | Membrane Proteins - genetics | Orthomyxoviridae Infections - metabolism | Epithelial Cells - pathology | Membrane Proteins - immunology | Interferon Regulatory Factor-7 - immunology | Interferon Regulatory Factor-7 - metabolism | Nerve Tissue Proteins - genetics | Mice, Knockout | Nerve Tissue Proteins - metabolism | Animals | Influenza A virus - metabolism | Epithelial Cells - immunology | Epithelial Cells - virology | Adaptor Proteins, Signal Transducing - genetics | Interferon Regulatory Factor-3 - metabolism | Interferon Type I - genetics | Mice | Respiratory Mucosa - metabolism | Adaptor Proteins, Signal Transducing - metabolism | Orthomyxoviridae Infections - immunology | Epithelial cells | Influenza | Physiological aspects | Host-parasite relationships | Interferon | Genetic aspects | Genetic transcription | Research | Health aspects | Airway (Medicine) | Index Medicus | Interleukins/metabolism | Nerve Tissue Proteins/immunology | Orthomyxoviridae Infections/genetics | Orthomyxoviridae Infections/metabolism | Membrane Proteins/genetics | Adaptor Proteins, Signal Transducing/genetics | Interferon Regulatory Factor-7/genetics | Interleukins/immunology | Membrane Proteins/immunology | Life Sciences | Orthomyxoviridae Infections/immunology | Influenza A virus/genetics | Nerve Tissue Proteins/metabolism | Respiratory Mucosa/immunology | Immunology | Interferon Type I/immunology | Epithelial Cells/immunology | Epithelial Cells/virology | Interferon Regulatory Factor-7/immunology | Epithelial Cells/metabolism | Interferon Regulatory Factor-3/immunology | Respiratory Mucosa/pathology | Influenza A virus/immunology | Interleukins/genetics | Interferon Regulatory Factor-3/genetics | Influenza A virus/metabolism | Adaptor Proteins, Signal Transducing/metabolism | Epithelial Cells/pathology | Adaptor Proteins, Signal Transducing/immunology | Interferon Type I/genetics | Interferon Regulatory Factor-3/metabolism | Membrane Proteins/metabolism | Nerve Tissue Proteins/genetics | Interferon Regulatory Factor-7/metabolism | Interferon Type I/metabolism | Respiratory Mucosa/metabolism | Respiratory Mucosa/virology | Cytokines | Genes | Rodents | Genomics | Genomes | Kinases | Experiments | Viral infections
Journal Article
PloS one, ISSN 1932-6203, 10/2012, Volume 7, Issue 10, pp. e48854 - e48854
...) in the host involves the migration of immature dendritic cells (iDCs). iDCs migrate in response to the HIV-1 envelope protein, gp120, and inhibiting such migration may limit the mucosal transmission of HIV-1... 
Science & Technology - Other Topics | Multidisciplinary Sciences | Science & Technology | Paxillin - metabolism | Proto-Oncogene Proteins pp60(c-src) - immunology | Pseudopodia - immunology | Human Umbilical Vein Endothelial Cells - metabolism | Dendritic Cells - immunology | Humans | Actins - metabolism | Human Umbilical Vein Endothelial Cells - immunology | cdc42 GTP-Binding Protein - metabolism | Paxillin - immunology | Actins - immunology | HIV Envelope Protein gp120 - metabolism | Cell Movement - immunology | HIV Envelope Protein gp120 - immunology | Intercellular Signaling Peptides and Proteins - metabolism | Signal Transduction - immunology | rac1 GTP-Binding Protein - immunology | Actin-Related Protein 2-3 Complex - metabolism | Focal Adhesion Kinase 2 - metabolism | RNA Interference | cdc42 GTP-Binding Protein - immunology | Wiskott-Aldrich Syndrome Protein - metabolism | Microfilament Proteins - metabolism | Receptors, Immunologic - immunology | Microfilament Proteins - genetics | Dendritic Cells - metabolism | Nerve Tissue Proteins - immunology | Cells, Cultured | Protein Binding - immunology | Blotting, Western | Actin-Related Protein 2-3 Complex - immunology | Nerve Tissue Proteins - metabolism | Microscopy, Confocal | Wiskott-Aldrich Syndrome Protein - immunology | Proto-Oncogene Proteins pp60(c-src) - metabolism | Microfilament Proteins - immunology | Intercellular Signaling Peptides and Proteins - immunology | Receptors, Immunologic - metabolism | rac1 GTP-Binding Protein - metabolism | Focal Adhesion Kinase 2 - immunology | Dendritic cells | HIV (Viruses) | Muscle proteins | Actin | Protein binding | Cdc42 protein | Sexually transmitted diseases--STD | Motility | Leukocyte migration | Mucosa | Viruses | Smooth muscle | Kinases | Tissues | Medical schools | Cell adhesion & migration | Proteins | Angiogenesis | Human immunodeficiency virus--HIV | Inhibition | Sequestering | Localization | Wiskott-Aldrich syndrome | LSP1 protein | Envelope protein | Rac1 protein | Glycoproteins | White blood cells | Medicine | Actin-related protein 2 | Signaling | Disease transmission | Ligands | Paxillin | Glycoprotein gp120 | Cell migration | Index Medicus | STD | Sexually transmitted diseases | HIV | Human immunodeficiency virus
Journal Article
Virus research, ISSN 0168-1702, 2011, Volume 162, Issue 1, pp. 12 - 18
Influenza A and B viruses are a major cause of respiratory disease in humans. In addition, influenza A viruses continuously re-emerge from animal reservoirs... 
Influenza A | Review | Type 1 interferon | Influenza B | Life Sciences & Biomedicine | Science & Technology | Virology | Antigens, CD - immunology | Ubiquitins - genetics | Virus Replication - genetics | Humans | Viral Proteins - immunology | eIF-2 Kinase - immunology | Interferon Type I - immunology | Antigens, CD - genetics | GTP-Binding Proteins - genetics | Viral Proteins - metabolism | Host-Pathogen Interactions - immunology | Orthomyxoviridae - immunology | Interferon Type I - biosynthesis | Myxovirus Resistance Proteins | Influenza, Human - virology | Cytokines - genetics | Cytokines - immunology | eIF-2 Kinase - genetics | DEAD Box Protein 58 | GPI-Linked Proteins - immunology | Ubiquitins - immunology | GTP-Binding Proteins - immunology | Toll-Like Receptors - immunology | Orthomyxoviridae - metabolism | Viral Proteins - genetics | Virus Replication - immunology | Immunity, Innate | Proteins - immunology | 2',5'-Oligoadenylate Synthetase - genetics | Proteins - genetics | DEAD-box RNA Helicases - genetics | Animals | Immune Evasion | 2',5'-Oligoadenylate Synthetase - immunology | Toll-Like Receptors - genetics | DEAD-box RNA Helicases - immunology | Antigens, Differentiation - genetics | Mice | Antigens, Differentiation - immunology | GPI-Linked Proteins - genetics | Influenza, Human - immunology | Influenza viruses | Interferon | Biological response modifiers | Health aspects | Influenza | Index Medicus
Journal Article
Immunity (Cambridge, Mass.), ISSN 1074-7613, 03/2015, Volume 42, Issue 3, pp. 431 - 442
... cells that are often deficient for multiple transcription factors and signaling proteins, including... 
Life Sciences & Biomedicine | Immunology | Science & Technology | Cell Proliferation | Humans | NK Cell Lectin-Like Receptor Subfamily C - genetics | Receptors, IgG - deficiency | Intracellular Signaling Peptides and Proteins - immunology | Cytomegalovirus Infections - immunology | Gene Expression Profiling | Killer Cells, Natural - pathology | Cytomegalovirus Infections - genetics | Protein-Tyrosine Kinases - deficiency | Protein-Tyrosine Kinases - immunology | Intracellular Signaling Peptides and Proteins - deficiency | NK Cell Lectin-Like Receptor Subfamily C - immunology | DNA Methylation | Protein-Tyrosine Kinases - genetics | Receptors, IgG - genetics | Microarray Analysis | Antibodies - immunology | Cytomegalovirus Infections - virology | Killer Cells, Natural - immunology | Cytomegalovirus Infections - pathology | Intracellular Signaling Peptides and Proteins - genetics | Syk Kinase | Promoter Regions, Genetic | GPI-Linked Proteins - immunology | Signal Transduction | Killer Cells, Natural - virology | NK Cell Lectin-Like Receptor Subfamily C - deficiency | Immunophenotyping | Receptors, IgG - immunology | Killer Cells, Natural - classification | Cytomegalovirus - immunology | Epigenesis, Genetic - immunology | Immunologic Memory | GPI-Linked Proteins - genetics | Proteins | Viral antibodies | Epigenetic inheritance | Killer cells | Molecular genetics | Antibodies | Gene expression | Antigens | Cytomegalovirus | Cloning | Colleges & universities | Infections | Experiments | Long term | DNA methylation | Epigenetics | Expansion | Viral infections | Deoxyribonucleic acid--DNA | Immune system | Index Medicus
Journal Article
PLoS pathogens, ISSN 1553-7374, 04/2014, Volume 10, Issue 4, pp. e1003989 - e1003989
...) gene induction and protein secretion in response to MVA infection. We report that MVA infection elicits the production of type I IFN in murine conventional dendritic cells (cDCs... 
Parasitology | Life Sciences & Biomedicine | Microbiology | Science & Technology | Virology | Dendritic Cells - immunology | Lysosomes - genetics | Immunity, Innate - genetics | Vaccinia virus - genetics | Viral Proteins - metabolism | Endosomes - metabolism | Bone Marrow Cells - virology | Phosphorylation - genetics | Bone Marrow Cells - immunology | Interferon-beta - genetics | Phosphorylation - immunology | Receptor, Interferon alpha-beta - genetics | Nucleotidyltransferases - metabolism | Vaccinia - metabolism | Protein-Serine-Threonine Kinases - metabolism | Receptor, Interferon alpha-beta - metabolism | Endosomes - genetics | Membrane Proteins - genetics | RNA-Binding Proteins - immunology | Viral Proteins - genetics | Mice, Knockout | Interferon-beta - metabolism | Receptor, Interferon alpha-beta - immunology | Vaccinia - immunology | Virulence Factors - metabolism | Mice | Lysosomes - immunology | RNA-Binding Proteins - metabolism | Endosomes - immunology | RNA-Binding Proteins - genetics | Interferon-beta - immunology | Virulence Factors - genetics | Viral Proteins - immunology | Virulence Factors - immunology | Interferon Regulatory Factor-3 - genetics | Vaccinia virus - immunology | Lysosomes - metabolism | Female | Membrane Proteins - metabolism | Dendritic Cells - virology | Dendritic Cells - metabolism | Interferon Regulatory Factor-3 - immunology | Vaccinia virus - metabolism | Protein-Serine-Threonine Kinases - genetics | Membrane Proteins - immunology | Vaccinia - genetics | Animals | Interferon Regulatory Factor-3 - metabolism | Nucleotidyltransferases - genetics | Protein-Serine-Threonine Kinases - immunology | Nucleotidyltransferases - immunology | Bone Marrow Cells - metabolism | Microbiological research | Dendritic cells | Genetic research | Genetic aspects | Research | Nucleotide sequencing | Vaccinia | Health aspects | DNA sequencing | Index Medicus | Proteins | Studies | Smallpox | Transcription factors | Genes | Deoxyribonucleic acid | DNA | Infections | Genomes | Vaccines | Viral infections | Immune system
Journal Article
The Journal of biological chemistry, ISSN 1083-351X, 10/2012, Volume 287, Issue 42, pp. 35631 - 35645
.... Our mutagenesis analyses of HCV pseudoparticles and cell culture-derived HCV using the H77 isolate indicate that five residues at positions 14, 15, and 25-27 mediate binding of the E2 protein... 
Life Sciences & Biomedicine | Biochemistry & Molecular Biology | Science & Technology | Protein Structure, Tertiary | CD36 Antigens - genetics | Antibodies, Viral - pharmacology | Humans | Viral Proteins - immunology | CD36 Antigens - immunology | Viral Proteins - genetics | Antibodies, Neutralizing - pharmacology | Hepatitis C - genetics | Viral Proteins - antagonists & inhibitors | Viral Proteins - metabolism | Virus Internalization | Hepatitis C - immunology | Viral Hepatitis Vaccines - immunology | Antibodies, Neutralizing - immunology | Immune Evasion | CD36 Antigens - metabolism | Viral Hepatitis Vaccines - genetics | Antibodies, Viral - immunology | Hepacivirus - physiology | Hepatitis C - prevention & control | Index Medicus | CD36 Antigens/genetics | Viral Proteins/genetics | Hepatitis C/prevention & control | Viral Proteins/antagonists & inhibitors | Antibodies, Viral/immunology | Life Sciences | Viral Hepatitis Vaccines/immunology | Antibodies, Neutralizing/immunology | Viral Proteins/immunology | Hepatitis C/genetics | CD36 Antigens/metabolism | Hepatitis C/immunology | Antibodies, Neutralizing/pharmacology | Viral Hepatitis Vaccines/genetics | CD36 Antigens/immunology | Antibodies, Viral/pharmacology | Hepacivirus/physiology | Virology | Microbiology and Parasitology | Human health and pathology | Infectious diseases | Viral Proteins/metabolism | Virus Entry | Viral Protein | Microbiology | Viral Immunology | Cell Surface Receptor | Hepatitis C Virus | Hypervariable Region 1
Journal Article
Nature (London), ISSN 1476-4687, 10/2014, Volume 514, Issue 7523, pp. 455 - 461
Journal Article