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1. Full Text Vaccine protection against Zika virus from Brazil
by Larocca, Rafael A and Abbink, Peter and Peron, Jean Pierre S and Zanotto, Paolo M. De A and Iampietro, M. Justin and Badamchi-Zadeh, Alexander and Boyd, Michael and Ng'ang'a, David and Kirilova, Marinela and Nityanandam, Ramya and Mercado, Noe B and Li, Zhenfeng and Moseley, Edward T and Bricault, Christine A and Borducchi, Erica N and Giglio, Patricia B and Jetton, David and Neubauer, George and Nkolola, Joseph P and Maxfield, Lori F and De La Barrera, Rafael A and Jarman, Richard G and Eckels, Kenneth H and Michael, Nelson L and Thomas, Stephen J and Barouch, Dan H
Nature, ISSN 0028-0836, 06/2016, Volume 536, Issue 7617, pp. 474 - 478
Zika virus (ZIKV) is a flavivirus that is responsible for the current epidemic in Brazil and the Americas(1,2). ZIKV has been causally associated with fetal... 
CHALLENGE | HEALTHY-ADULTS | IMMUNOGENICITY | AMERICA | NEUTRALIZING ANTIBODY | SAFETY | MULTIDISCIPLINARY SCIENCES | INFECTION | MICE | MODEL | Antibody Specificity | Immunoglobulin G - isolation & purification | Vaccines, DNA - genetics | Zika Virus - genetics | Vaccines, Subunit - genetics | Humans | Viral Vaccines - genetics | Vaccines, DNA - immunology | Adoptive Transfer | Microcephaly - virology | CD4-Positive T-Lymphocytes - immunology | Zika Virus Infection - virology | Antibodies, Neutralizing - immunology | Immunoglobulin G - immunology | Gene Deletion | Brazil | Zika Virus Infection - complications | Female | Zika Virus Infection - prevention & control | Zika Virus - immunology | Microcephaly - complications | Vaccines, Inactivated - genetics | Viral Envelope Proteins - genetics | Vaccines, Subunit - chemistry | Vaccines, Subunit - immunology | Zika Virus - chemistry | Vaccines, DNA - chemistry | Vaccines, Inactivated - immunology | Animals | Viral Envelope Proteins - chemistry | Viral Vaccines - chemistry | Zika Virus Infection - immunology | Antibodies, Viral - immunology | Viral Envelope Proteins - immunology | Mice | CD8-Positive T-Lymphocytes - immunology | Viral Vaccines - immunology | Vaccines, Inactivated - chemistry | Product development | Viral vaccines | Studies | Epidemics | Encephalitis | Immunization | Fetuses | Zika virus | Vaccines | Microcephaly | Deoxyribonucleic acid--DNA
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2. Full Text HSV-1 amplicon vectors as genetic vaccines
by Laimbacher, Andrea S and Fraefel, Cornel
Methods in molecular biology (Clifton, N.J.), ISSN 1064-3745, 2014, Volume 1144, pp. 99 - 115
HSV-1 amplicon vectors have been used as platforms for the generation of genetic vaccines against both DNA and RNA viruses. Mice vaccinated with such vectors... 
Polycistronic transgene cassette | Viruslike particles | Genetic vaccine | Helper virus-free HSV-1 amplicon vector | Foot-and-Mouth Disease Virus - genetics | Rotavirus - pathogenicity | Viral Vaccines - therapeutic use | Foot-and-Mouth Disease - therapy | Humans | Rotavirus Infections - therapy | Viral Vaccines - genetics | Rotavirus - immunology | Cercopithecus aethiops | Rotavirus - genetics | Foot-and-Mouth Disease - prevention & control | Viral Structural Proteins - immunology | Viral Structural Proteins - antagonists & inhibitors | Foot-and-Mouth Disease - immunology | Molecular Biology - methods | Rotavirus Infections - immunology | Animals | Foot-and-Mouth Disease Virus - immunology | Herpesvirus 1, Human - genetics | Herpesvirus 1, Human - immunology | Mice | Vero Cells | Rotavirus Infections - prevention & control
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3. Full Text Vector Choice Determines Immunogenicity and Potency of Genetic Vaccines against Angola Marburg Virus in Nonhuman Primates
by Thomas W. Geisbert and Michael Bailey and Joan B. Geisbert and Clement Asiedu and Mario Roederer and Maria Grazia-Pau and Jerome Custers and Peter Jahrling and Jaap Goudsmit and Richard Koup and Nancy J. Sullivan
Journal of Virology, ISSN 0022-538X, 10/2010, Volume 84, Issue 19, pp. 10386 - 10394
Article Usage Stats Services JVI Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley... 
PATHOGENESIS | T-CELL RESPONSES | VIROLOGY | DNA VACCINES | PROTECTION | HEMORRHAGIC-FEVER | VACCINATION | HUMANS | INFECTION | GUINEA-PIGS | EBOLA-VIRUS | Vaccines, DNA - genetics | Cytokines - metabolism | Marburg Virus Disease - immunology | Viral Vaccines - pharmacology | Viral Vaccines - genetics | Vaccines, DNA - immunology | Viral Proteins - immunology | Macaca fascicularis | Viral Proteins - genetics | Marburgvirus - genetics | CD4-Positive T-Lymphocytes - immunology | Animals | Immunization, Secondary | Genes, Viral | Marburgvirus - immunology | Models, Animal | Marburg Virus Disease - prevention & control | CD8-Positive T-Lymphocytes - immunology | Genetic Vectors | Immunity, Cellular | Vaccines, DNA - pharmacology | Viral Vaccines - immunology | Vaccines and Antiviral Agents
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4. Full Text Preclinical and clinical development of YFV 17D-based chimeric vaccines against dengue, West Nile and Japanese encephalitis viruses
by Guy, Bruno and Guirakhoo, Farshad and Barban, Veronique and Higgs, Stephen and Monath, Thomas P and Lang, Jean
Vaccine, ISSN 0264-410X, 2009, Volume 28, Issue 3, pp. 632 - 649
Abstract Dengue viruses (DENV), West Nile virus (WNV) and Japanese encephalitis virus (JEV) are major global health and growing medical problems. While a... 
Allergy and Immunology | Vaccine | Flavivirus | Dengue | West Nile virus | Japanese encephalitis | Chimera | NONHUMAN-PRIMATES | 17D VACCINE | MEDICINE, RESEARCH & EXPERIMENTAL | HUMAN DENDRITIC CELLS | IMMUNOLOGY | BLOOD MONONUCLEAR-CELLS | ANTIBODY-DEPENDENT ENHANCEMENT | ATTENUATED FLAVIVIRUS VACCINES | HEMORRHAGIC-FEVER | YELLOW-FEVER VIRUS | GROWTH-CHARACTERISTICS | AEDES-AEGYPTI MOSQUITOS | Humans | Japanese Encephalitis Vaccines - immunology | Vaccines, Synthetic - genetics | Viral Proteins - genetics | Vaccines, Synthetic - immunology | Dengue Vaccines - genetics | West Nile Virus Vaccines - immunology | Encephalitis Virus, Japanese - genetics | Dengue Vaccines - immunology | Dengue Virus - genetics | Vaccines, Attenuated - immunology | West Nile virus - genetics | West Nile Virus Vaccines - genetics | Genetic Vectors | Japanese Encephalitis Vaccines - genetics | Vaccines, Attenuated - genetics | Yellow fever virus - genetics | Encephalitis | Disease | Dengue fever | Horses | Viruses | Infections | Vaccines
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5. Full Text Fully Detargeted Polyethylene Glycol-coated Adenovirus Vectors Are Potent Genetic Vaccines and Escape from Pre-existing Anti-adenovirus Antibodies
by Wortmann, Andreas and Vöhringer, Sabine and Engler, Tatjana and Corjon, Stephanie and Schirmbeck, Reinhold and Reimann, Jörg and Kochanek, Stefan and Kreppel, Florian
Molecular Therapy, ISSN 1525-0016, 01/2008, Volume 16, Issue 1, pp. 154 - 162
Genetic vaccination with adenoviral (Ad) gene transfer vectors requires transduction of professional antigen-presenting cells. However, because the natural Ad... 
MEDICINE, RESEARCH & EXPERIMENTAL | CELL INFECTION | VIRUS | PROTECTION | IMMUNOGENICITY | INNATE IMMUNE-RESPONSES | BIOTECHNOLOGY & APPLIED MICROBIOLOGY | IN-VIVO | LIVER | GENETICS & HEREDITY | EXPRESSION | RECOMBINANT ADENOVIRUS | PEGYLATION | Antibodies, Viral - biosynthesis | Polyethylene Glycols - metabolism | Vaccines, DNA - genetics | Molecular Weight | Transduction, Genetic | Genetic Vectors - administration & dosage | Genetic Vectors - immunology | Humans | Viral Vaccines - genetics | Vaccines, DNA - immunology | Genetic Vectors - metabolism | Antibodies, Viral - blood | Vaccines, DNA - administration & dosage | Viral Vaccines - administration & dosage | Animals | K562 Cells | Adenoviridae - genetics | Cell Line, Tumor | Immune Tolerance - genetics | Female | Mice | Mice, Inbred BALB C | Adenoviridae - immunology | Viral Vaccines - immunology
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6. Full Text Chimpanzee adenovirus vaccine generates acute and durable protective immunity against ebolavirus challenge
by Stanley, Daphne A and Stanley, Daphne A and Honko, Anna N and Asiedu, Clement and Trefry, John C and Lau-Kilby, Annie W and Johnson, Joshua C and Hensley, Lisa and Ammendola, Virginia and Abbate, Adele and Grazioli, Fabiana and Foulds, Kathryn E and Cheng, Cheng and Wang, Lingshu and Donaldson, Mitzi M and Colloca, Stefano and Folgori, Antonella and Roederer, Mario and Nabel, Gary J and Mascola, John and Nicosia, Alfredo and Cortese, Riccardo and Koup, Richard A and Sullivan, Nancy J
Nature medicine, ISSN 1078-8956, 10/2014, Volume 20, Issue 10, pp. 1126 - 1129
Ebolavirus disease causes high mortality, and the current outbreak has spread unabated through West Africa. Human adenovirus type 5 vectors (rAd5) encoding... 
NONHUMAN-PRIMATES | MEDICINE, RESEARCH & EXPERIMENTAL | IMMUNOGENICITY | QUALITY | VIRUS INFECTION | BIOCHEMISTRY & MOLECULAR BIOLOGY | VECTOR | CELL BIOLOGY | Ebola Vaccines - genetics | Adenoviruses, Simian - immunology | Hemorrhagic Fever, Ebola - prevention & control | Humans | Macaca fascicularis | RNA, Viral - blood | Ebolavirus - genetics | Vaccinia virus - genetics | Ebolavirus - immunology | Vaccinia virus - immunology | Adenoviruses, Simian - genetics | Immunization, Secondary | RNA, Viral - genetics | Time Factors | Adenovirus Vaccines - genetics | Hemorrhagic Fever, Ebola - virology | Ebola Vaccines - immunology | Female | Hemorrhagic Fever, Ebola - immunology | Adenovirus Vaccines - administration & dosage | Adenoviruses, Human - immunology | Defective Viruses - genetics | Ebola Vaccines - administration & dosage | Pan troglodytes | Adenovirus Vaccines - immunology | Animals | Defective Viruses - immunology | Adenoviruses, Human - genetics | Genetic Vectors | Ebola virus | Physiological aspects | Viral vaccines | Research | Analysis | Vaccines | Monkeys & apes | Adenoviruses | Immune system
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7. Full Text A non-human hepadnaviral adjuvant for hepatitis C virus-based genetic vaccines
by Levander, Sepideh and Sällberg, Matti and Ahlén, Gustaf and Frelin, Lars
Vaccine, ISSN 0264-410X, 2016, Volume 34, Issue 25, pp. 2821 - 2833
Highlights • Hepatitis C virus (HCV) is the major causative agent for severe liver disease and cancer. • No prophylactic or therapeutic vaccines are available... 
Allergy and Immunology | Electroporation | HCV | Adjuvant | Delivery | Hepatitis C virus | Genetic vaccine | MEDICINE, RESEARCH & EXPERIMENTAL | B CORE ANTIGEN | IMMUNOLOGY | PEPTIDE | IMMUNOGENICITY | INTERFERON | T-CELL RESPONSES | EPITOPE | DNA IMMUNIZATION | IMMUNE-RESPONSES | INFECTION | TRANSGENIC MICE | Adjuvants, Immunologic - pharmacology | Humans | Mice, Inbred C57BL | Vaccines, DNA - immunology | Birds | Mice, Transgenic | Hep G2 Cells | Hepatitis B Core Antigens - immunology | Viral Hepatitis Vaccines - immunology | Animals | Immunization, Secondary | Interleukin-12 - administration & dosage | Interleukin-2 - immunology | Interferon-gamma - immunology | Female | T-Lymphocytes - immunology | Mice | Hepadnaviridae - immunology | Hepatitis C - prevention & control | Hepacivirus | Viral Nonstructural Proteins - immunology | Health aspects | Vaccines | Antigens | Liver | Genetic engineering | T cells | Liver diseases | Peptides | Laboratories | Mortality | Infections | Genotype & phenotype | Hepatitis | Lymphocytes | Conflicts of interest | Deoxyribonucleic acid--DNA
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8. Full Text Novel AAV-based genetic vaccines encoding truncated dengue virus envelope proteins elicit humoral immune responses in mice
by Li, Xueling and Li, Gang and Cao, Hong and Wang, Ming and Wang, Qiang and Wang, Lili and Di, Biao and Lu, Jianxi and Pan, Lijie and Pan, Xingfei and Yang, Li and Mei, Mingzhu
Microbes and Infection, ISSN 1286-4579, 09/2012, Volume 14, Issue 11, pp. 1000 - 1007
The envelope protein of dengue virus is involved in host cell attachment for entry and induction of protective immunity. Current efforts are focused on... 
Dengue virus | Envelope | Genetic vaccine | AAV | INFECTIOUS DISEASES | NEUTRALIZING ANTIBODIES | RHESUS-MONKEYS | MICROBIOLOGY | INDUCTION | IMMUNOLOGY | ADENOASSOCIATED VIRUSES | IMMUNOGENICITY | REPLICATION | DNA VACCINES | RECOMBINANT | GLYCOPROTEIN | VECTORS | Dependovirus - genetics | Vaccines, DNA - genetics | Viral Envelope Proteins - genetics | Immunity, Humoral - immunology | Mice, Inbred C57BL | Viral Vaccines - genetics | Vaccines, DNA - immunology | Viral Vaccines - metabolism | Antigens, Viral - genetics | Male | Blotting, Western | Antigens, Viral - immunology | Dengue Virus - genetics | Animals | Dengue Virus - immunology | Immunoglobulin G - immunology | Cloning, Molecular | Plasmids - genetics | Viral Envelope Proteins - metabolism | Antibodies, Viral - immunology | Viral Envelope Proteins - immunology | Mice | Vaccines, DNA - metabolism | Viral Vaccines - immunology | Antigens | Immune response | Dengue | Genetic research | Cross infection | Vaccines | Nosocomial infections | Gene therapy
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9. Full Text Potent CD8⁺ T-Cell Immunogenicity in Humans of a Novel Heterosubtypic Influenza A Vaccine, MVA−NP+M1
by Tamara K. Berthoud and Matthew Hamill and Patrick J. Lillie and Lenias Hwenda and Katharine A. Collins and Katie J. Ewer and Anita Milicic and Hazel C. Poyntz and Teresa Lambe and Helen A. Fletcher and Adrian V. S. Hill and Sarah C. Gilbert
Clinical Infectious Diseases, ISSN 1058-4838, 1/2011, Volume 52, Issue 1, pp. 1 - 7
Background. Influenza A viruses cause occasional pandemics and frequent epidemics. Licensed influenza vaccines that induce high antibody titers to the highly... 
T lymphocytes | H1N1 subtype influenza A virus | Influenza vaccines | Antigens | Volunteerism | Immune response | Influenza A virus | Vaccination | Viruses | ARTICLES AND COMMENTARIES | H5N1 subtype influenza A virus | INFECTIOUS DISEASES | VIRUS | H5N1 VACCINE | SAFETY | CIRCUMSPOROZOITE PROTEIN | MICROBIOLOGY | IMMUNOLOGY | VIRAL VECTORS | IMMUNIZATION | HEALTHY-ADULTS | RECOMBINANT | DNA | FOWLPOX STRAIN FP9 | RNA-Binding Proteins - genetics | Viral Matrix Proteins - genetics | Vaccines, Subunit - genetics | Humans | Middle Aged | Male | Vaccines, Synthetic - immunology | Vaccinia virus - genetics | Drug Carriers | Young Adult | Vaccines, Synthetic - adverse effects | Adult | Female | Vaccines, Subunit - adverse effects | Injections, Intradermal | Interferon-gamma - secretion | RNA-Binding Proteins - immunology | Vaccines, Synthetic - genetics | Influenza Vaccines - adverse effects | Vaccines, Subunit - immunology | Injections, Intramuscular | Influenza Vaccines - immunology | Influenza Vaccines - genetics | Viral Core Proteins - genetics | Adolescent | Viral Core Proteins - immunology | Viral Matrix Proteins - immunology | CD8-Positive T-Lymphocytes - immunology | Genetic Vectors | and Commentaries
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10. Full Text Cloned cDNA of A/swine/Iowa/15/1930 internal genes as a candidate backbone for reverse genetics vaccine against influenza A viruses
by Lekcharoensuk, Porntippa and Wiriyarat, Witthawat and Petcharat, Nantawan and Lekcharoensuk, Chalermpol and Auewarakul, Prasert and Richt, Juergen A
Vaccine, ISSN 0264-410X, 2011, Volume 30, Issue 8, pp. 1453 - 1459
Highlights ► The novel 8 plasmid reverse genetics of influenza A virus, rg1930, was generated. ► Each gene contains the introduced genetic marker for easy... 
Allergy and Immunology | Cell-based vaccine | Influenza A virus | Reverse genetics vaccine | Avian influenza virus subtype H5N1 | Vaccine efficacy | MEDICINE, RESEARCH & EXPERIMENTAL | EFFICACY | VERO | PROTECTION | SWINE | CHICKENS | IMMUNOLOGY | H5N1 | TRANSMISSION | EVOLUTION | GENERATION | PATHOGENIC AVIAN INFLUENZA | Influenza Vaccines - administration & dosage | Influenza in Birds - prevention & control | Reverse Genetics - methods | Cercopithecus aethiops | Molecular Sequence Data | Influenza A Virus, H5N1 Subtype - genetics | Vaccines, Synthetic - immunology | Antibodies, Viral - blood | Hemagglutination Inhibition Tests | Swine | Influenza A Virus, H1N1 Subtype - genetics | Disease Models, Animal | Cell Line | Vaccines, Inactivated - genetics | Vaccines, Synthetic - genetics | Sequence Analysis, DNA | Iowa | Vaccines, Inactivated - immunology | Animals | Influenza Vaccines - immunology | Influenza Vaccines - genetics | Vaccines, Inactivated - administration & dosage | Influenza A Virus, H5N1 Subtype - immunology | Chickens | Dogs | Vaccines, Synthetic - administration & dosage | DNA, Complementary | Influenza viruses | Avian influenza | Influenza vaccines | Virus diseases | Cloning | Genes | Genetics | Animal genetic engineering | Universities and colleges | Immunization | Pandemics | Vaccines | Poultry | Avian flu | cell-based vaccine | avian influenza virus subtype H5N1 | vaccine efficacy | reverse genetics vaccine
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11. Full Text Live attenuated recombinant vaccine protects nonhuman primates against Ebola and Marburg viruses
by Feldmann, Heinz and Daddario, Kathleen M and Geisbert, Joan B and Klenk, Hans-Dieter and Jahrling, Peter B and Ströher, Ute and Fritz, Elizabeth A and Geisbert, Thomas W and Hensley, Lisa E and Fernando, Lisa and Volchkov, Viktor E and Sullivan, Nancy J and Jones, Steven M and Grolla, Allen
Nature Medicine, ISSN 1078-8956, 07/2005, Volume 11, Issue 7, pp. 786 - 790
Vaccines and therapies are urgently needed to address public health needs stemming from emerging pathogens and biological threat agents such as the filoviruses... 
MEDICINE, RESEARCH & EXPERIMENTAL | INFECTIONS | HEMORRHAGIC-FEVER | BIOCHEMISTRY & MOLECULAR BIOLOGY | DISEASE | GLYCOPROTEINS | VECTORS | VESICULAR STOMATITIS VIRUSES | CHILDREN | CELL BIOLOGY | Vaccines, Attenuated - pharmacology | Vesicular stomatitis Indiana virus - genetics | Viral Vaccines - pharmacology | Vaccines, Synthetic - genetics | Vaccines, Synthetic - pharmacology | Viral Vaccines - genetics | Vaccines, Synthetic - immunology | Vaccines, Combined - immunology | Ebolavirus - immunology | Cross Reactions | Vaccines, Attenuated - immunology | Animals | Vaccines, Combined - pharmacology | Viremia - virology | Virus Replication | Antibody Formation | Marburgvirus - immunology | Primates | Vaccines, Combined - genetics | Ebola Vaccines - immunology | Viremia - immunology | Viral Vaccines - immunology | Ebola Vaccines - pharmacology | Vaccines, Attenuated - genetics
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