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1. Full Text Suramin inhibits Zika virus replication by interfering with virus attachment and release of infectious particles
by Albulescu, Irina C and Kovacikova, Kristina and Tas, Ali and Snijder, Eric J and van Hemert, Martijn J
Antiviral research, ISSN 0166-3542, 07/2017, Volume 143, pp. 230 - 236
Pharmacology & Pharmacy | Life Sciences & Biomedicine | Science & Technology | Virology | Mycophenolic Acid - antagonists & inhibitors | Zika Virus Infection - drug therapy | Cytopathogenic Effect, Viral - drug effects | DNA Replication - drug effects | Cercopithecus aethiops | Glycosylation - drug effects | Virus Internalization - drug effects | Suramin - administration & dosage | Suramin - antagonists & inhibitors | Zika Virus Infection - virology | Time Factors | Flavivirus - drug effects | Mycophenolic Acid - administration & dosage | Vero Cells | Virus Replication - drug effects | Zika Virus - growth & development | RNA, Viral - biosynthesis | Zika Virus - physiology | RNA, Viral - analysis | Zika Virus - drug effects | Virion - drug effects | Virus Attachment - drug effects | Virus Release - drug effects | Animals | RNA, Viral - drug effects | Birth defects | Conjunctivitis | Microbiology | RNA | Guillain-Barre syndrome | Index Medicus
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2. Full Text Ex vivo analysis identifies effective HIV-1 latency-reversing drug combinations
by Laird, Gregory M and Bullen, C. Korin and Rosenbloom, Daniel I. S and Martin, Alyssa R and Hill, Alison L and Durand, Christine M and Siliciano, Janet D and Siliciano, Robert F
The Journal of clinical investigation, ISSN 0021-9738, 05/2015, Volume 125, Issue 5, pp. 1901 - 1912
Life Sciences & Biomedicine | Medicine, Research & Experimental | Science & Technology | Research & Experimental Medicine | Anti-HIV Agents - pharmacology | Transcription, Genetic - drug effects | Lymphokines - secretion | Humans | Middle Aged | RNA, Messenger - analysis | Male | Virus Latency - drug effects | Anti-HIV Agents - administration & dosage | HIV-1 - physiology | Phorbol Esters - pharmacology | Adult | Anti-HIV Agents - therapeutic use | Female | CD4-Positive T-Lymphocytes - virology | Drug Evaluation, Preclinical | Bryostatins - pharmacology | HIV-1 - drug effects | Lymphocyte Activation | HIV Infections - virology | Protein Kinase C - drug effects | Cells, Cultured | RNA, Viral - analysis | Virion - metabolism | Azepines - pharmacology | Drug Synergism | Triazoles - pharmacology | CD4-Positive T-Lymphocytes - secretion | HIV Infections - drug therapy | Histone Deacetylase Inhibitors - pharmacology | Disulfiram - pharmacology | CD4-Positive T-Lymphocytes - drug effects | Physiological aspects | Research | RNA | T cells | Drug therapy | HIV infection | Studies | Statistical analysis | Cytokines | Acquired immune deficiency syndrome--AIDS | Lymphocytes | T cell receptors | Mathematical models | Gene expression | Index Medicus | Abridged Index Medicus | HIV | Infectious disease | AIDS
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3. Full Text Luteolin restricts dengue virus replication through inhibition of the proprotein convertase furin
by Peng, Minhua and Watanabe, Satoru and Chan, Kitti Wing Ki and He, Qiuyan and Zhao, Ya and Zhang, Zhongde and Lai, Xiaoping and Luo, Dahai and Vasudevan, Subhash G and Li, Geng
Antiviral research, ISSN 0166-3542, 07/2017, Volume 143, pp. 176 - 185
Traditional Chinese medicine | Virus maturation | Furin | Antiviral therapy | Luteolin | Dengue virus | Pharmacology & Pharmacy | Life Sciences & Biomedicine | Science & Technology | Virology | Dengue Virus - classification | DNA Replication - drug effects | Humans | Drugs, Chinese Herbal - pharmacology | Male | Dengue - drug therapy | Antiviral Agents - chemistry | Luteolin - chemistry | HEK293 Cells | Luteolin - administration & dosage | Proprotein Convertases - drug effects | Disease Models, Animal | Furin - metabolism | A549 Cells | Cell Line | Cell Survival - drug effects | Luteolin - antagonists & inhibitors | Virus Replication - drug effects | Antiviral Agents - pharmacology | Cricetinae | Dengue Virus - drug effects | Proprotein Convertases - metabolism | Dengue - virology | Viremia - drug therapy | Enzyme Activation - drug effects | Virion - drug effects | trans-Golgi Network - drug effects | Dengue Virus - genetics | Animals | Mice | Kinetics | RNA, Viral - drug effects | Virus diseases | Antiviral agents | Proteases | Analysis | Dengue viruses | Medicine, Chinese | Health aspects | Cells | Index Medicus
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4. Full Text FDA-approved selective estrogen receptor modulators inhibit ebola virus infection
by Johansen, Lisa M and Brannan, Jennifer M and Delos, Sue E and Shoemaker, Charles J and Stossel, Andrea and Lear, Calli and Hoffstrom, Benjamin G and DeWald, Lisa Evans and Schornberg, Kathryn L and Scully, Corinne and Lehár, Joseph and Hensley, Lisa E and White, Judith M and Olinger, Gene G
Science translational medicine, ISSN 1946-6234, 06/2013, Volume 5, Issue 190, pp. 190ra79 - 190ra79
Life Sciences & Biomedicine | Medicine, Research & Experimental | Science & Technology | Cell Biology | Research & Experimental Medicine | Receptors, Estrogen - metabolism | United States | Humans | Cercopithecus aethiops | Drug Approval | Virus Internalization - drug effects | Endosomes - metabolism | Dose-Response Relationship, Drug | Ebolavirus - drug effects | Selective Estrogen Receptor Modulators - therapeutic use | Hemorrhagic Fever, Ebola - virology | Hydrogen-Ion Concentration - drug effects | Toremifene - therapeutic use | Endosomes - drug effects | Hemorrhagic Fever, Ebola - drug therapy | Vero Cells | Toremifene - pharmacology | United States Food and Drug Administration | Disease Models, Animal | Clomiphene - pharmacology | Mice, Inbred C57BL | Hep G2 Cells | Virion - drug effects | Clomiphene - therapeutic use | Animals | Cathepsins - metabolism | Survival Analysis | Mice | Ebolavirus - physiology | Selective Estrogen Receptor Modulators - pharmacology | Index Medicus
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5. Full Text A targeted spatial-temporal proteomics approach implicates multiple cellular trafficking pathways in human cytomegalovirus virion maturation
by Moorman, Nathaniel J and Sharon-Friling, Ronit and Shenk, Thomas and Cristea, Ileana M
Molecular & cellular proteomics, ISSN 1535-9476, 05/2010, Volume 9, Issue 5, pp. 851 - 860
Humans | Molecular Sequence Data | Brefeldin A - pharmacology | Host-Pathogen Interactions - drug effects | Protein Transport - drug effects | Viral Proteins - metabolism | Time Factors | Nucleocapsid - metabolism | Protein Binding - drug effects | Recombination, Genetic - genetics | Proteomics - methods | Cytomegalovirus - physiology | Fibroblasts - metabolism | Fibroblasts - virology | Amino Acid Sequence | Viral Proteins - chemistry | Endosomal Sorting Complexes Required for Transport - metabolism | Virion - metabolism | Nucleocapsid - drug effects | Clathrin - chemistry | Clathrin - metabolism | Virion - drug effects | Models, Biological | Fibroblasts - drug effects | Cell Compartmentation - drug effects | Virus Assembly - drug effects | Recombination, Genetic - drug effects | Cytomegalovirus - drug effects | Index Medicus | Protein Interactions | Protein
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6. Full Text Broad spectrum anti-flavivirus pyridobenzothiazolones leading to less infective virions
by Cannalire, Rolando and Tarantino, Delia and Piorkowski, Geraldine and Carletti, Tea and Massari, Serena and Felicetti, Tommaso and Barreca, Maria Letizia and Sabatini, Stefano and Tabarrini, Oriana and Marcello, Alessandro and Milani, Mario and Cecchetti, Violetta and Mastrangelo, Eloise and Manfroni, Giuseppe and Querat, Gilles
Antiviral research, ISSN 0166-3542, 07/2019, Volume 167, pp. 6 - 12
Dengue inhibitors | Flavivirus replication | Zika virus | Flavivirus inhibitors | Antiviral small molecules | Antivirals | Pharmacology & Pharmacy | Life Sciences & Biomedicine | Science & Technology | Virology | Virus Replication - drug effects | Antiviral Agents - pharmacology | Flaviviridae - drug effects | Dengue Virus - drug effects | Humans | Pyridines - chemical synthesis | Oxazocines - pharmacology | Zika Virus - drug effects | West Nile virus - drug effects | Virion - drug effects | Encephalitis Viruses, Tick-Borne - drug effects | Yellow fever virus - drug effects | Animals | Antiviral Agents - chemical synthesis | Pyridines - pharmacology | RNA, Viral - drug effects | Oxazocines - chemical synthesis | Index Medicus | Life Sciences | Microbiology and Parasitology
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7. Full Text Modelling hepatitis C therapy-predicting effects of treatment
by Perelson, Alan S and Guedj, Jeremie and Los Alamos National Lab. (LANL), Los Alamos, NM (United States)
Nature reviews. Gastroenterology & hepatology, ISSN 1759-5045, 08/2015, Volume 12, Issue 8, pp. 437 - 445
Gastroenterology & Hepatology | Life Sciences & Biomedicine | Science & Technology | Biomarkers - metabolism | Antiviral Agents - pharmacokinetics | Antiviral Agents - therapeutic use | Humans | Drug Resistance, Viral | Interferon-alpha - therapeutic use | Treatment Outcome | Hepatitis C, Chronic - drug therapy | Liver Regeneration - physiology | Viral Load | Virion - drug effects | Time Factors | Models, Biological | Interferon-alpha - pharmacokinetics | RNA, Viral - metabolism | Drug Therapy, Combination | RNA, Viral - drug effects | Antiviral agents | Complications and side effects | Dosage and administration | Research | Hepatitis C | Drug therapy | Index Medicus | BASIC BIOLOGICAL SCIENCES | Biological Science
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8. Full Text The intracellular cholesterol transport inhibitor U18666A inhibits the exosome-dependent release of mature hepatitis C virus
by Elgner, Fabian and Ren, Huimei and Medvedev, Regina and Ploen, Daniela and Himmelsbach, Kiyoshi and Boller, Klaus and Hildt, Eberhard
Journal of virology, ISSN 0022-538X, 2016, Volume 90, Issue 24, pp. 11181 - 11196
Life Sciences & Biomedicine | Science & Technology | Virology | Exosomes - drug effects | Multivesicular Bodies - drug effects | Humans | Androstenes - pharmacology | Multivesicular Bodies - virology | Hepacivirus - physiology | Biological Transport - drug effects | Genes, Reporter | Hepatocytes - drug effects | Exosomes - ultrastructure | Exosomes - virology | Hepacivirus - drug effects | Gene Expression | Multivesicular Bodies - ultrastructure | Virion - physiology | Virus Assembly - physiology | Cholesterol - metabolism | Virion - drug effects | Virus Release - drug effects | Animals | Cell Line, Tumor | Hepatocytes - ultrastructure | Hepatocytes - virology | Virion - ultrastructure | Luminescent Proteins - genetics | Hepacivirus - ultrastructure | Anticholesteremic Agents - pharmacology | Luminescent Proteins - metabolism | Index Medicus
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9. Full Text Characterization of the mode of action of a potent dengue virus capsid inhibitor
by Scaturro, Pietro and Trist, Iuni Margaret Laura and Paul, David and Kumar, Anil and Acosta, Eliana G and Byrd, Chelsea M and Jordan, Robert and Brancale, Andrea and Bartenschlager, Ralf
Journal of virology, ISSN 0022-538X, 2014, Volume 88, Issue 19, pp. 11540 - 11555
Life Sciences & Biomedicine | Science & Technology | Virology | Capsid - chemistry | Heterocyclic Compounds, 3-Ring - pharmacology | Humans | Cercopithecus aethiops | Molecular Sequence Data | Crystallography, X-Ray | Virion - chemistry | Virus Internalization - drug effects | Capsid - drug effects | Antiviral Agents - chemistry | Thiadiazoles - chemistry | Capsid Proteins - chemistry | HEK293 Cells | Vero Cells | Hepatocytes - drug effects | Thiadiazoles - pharmacology | Amino Acid Sequence | Antiviral Agents - pharmacology | Cricetinae | Dengue Virus - drug effects | Dengue Virus - chemistry | Virion - drug effects | Virus Release - drug effects | Sequence Alignment | Animals | Capsid Proteins - antagonists & inhibitors | Heterocyclic Compounds, 3-Ring - chemistry | Cell Line, Tumor | Hepatocytes - virology | Virus Assembly - drug effects | Dengue Virus - physiology | Molecular Docking Simulation | Index Medicus | Vaccines and Antiviral Agents
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