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PLoS Pathogens, ISSN 1553-7366, 2014, Volume 10, Issue 6, pp. e1004174 - e1004174
Bacterial signaling systems are prime drug targets for combating the global health threat of antibiotic resistant bacterial infections including those caused... 
NADPH OXIDASE | ANTIBIOTICS | LYTTR DOMAIN | MODE | MICROBIOLOGY | INDUCTION | VIRULENCE | IDENTIFICATION | DISCOVERY | VIROLOGY | GENE-EXPRESSION | SKIN | PARASITOLOGY | Staphylococcus epidermidis - physiology | Skin - microbiology | Molecular Conformation | Bacterial Proteins - chemistry | Male | Promoter Regions, Genetic - drug effects | Trans-Activators - chemistry | Staphylococcal Skin Infections - immunology | Anti-Bacterial Agents - adverse effects | Macrophages - microbiology | Triazoles - therapeutic use | Bacterial Proteins - antagonists & inhibitors | Quorum Sensing - drug effects | Mice, Knockout | Macrophages - metabolism | Staphylococcus epidermidis - growth & development | Staphylococcus aureus - immunology | Anti-Bacterial Agents - pharmacology | Molecular Docking Simulation | Quinazolinones - chemistry | Mutation | Staphylococcal Skin Infections - microbiology | Triazoles - adverse effects | Staphylococcus epidermidis - drug effects | Staphylococcus aureus - physiology | Staphylococcus epidermidis - immunology | Triazoles - chemistry | Anti-Bacterial Agents - therapeutic use | Staphylococcal Skin Infections - drug therapy | Anti-Bacterial Agents - chemistry | Trans-Activators - genetics | Macrophages - immunology | Quinazolinones - pharmacology | Molecular Targeted Therapy - adverse effects | Phagocytosis - drug effects | Immunity, Innate - drug effects | Bacterial Proteins - genetics | Mice, Hairless | Drug Discovery | Triazoles - pharmacology | Animals | High-Throughput Screening Assays | Bacterial Proteins - metabolism | Genes, Reporter - drug effects | Macrophages - drug effects | Trans-Activators - metabolism | Quinazolinones - therapeutic use | Trans-Activators - antagonists & inhibitors | Staphylococcus aureus - drug effects | Staphylococcus aureus - growth & development | Cell Line, Transformed | Quinazolinones - adverse effects | Skin - drug effects | Staphylococcus aureus infections | Physiological aspects | Development and progression | Genetic aspects | Quorum sensing | Virulence (Microbiology) | Research | Staphylococcus aureus | Index Medicus | Medical research | Bacteria | Staphylococcus infections | Bacterial infections | Antibiotics | Bacteriology
Journal Article
PLoS Pathogens, ISSN 1553-7366, 2014, Volume 10, Issue 5, pp. e1004152 - e1004152
Bacteria form multicellular communities known as biofilms that cause two thirds of all infections and demonstrate a 10 to 1000 fold increase in adaptive... 
BACTERIA | (P)PPGPP | ESCHERICHIA-COLI | ANTIBACTERIAL | MICROBIOLOGY | PPGPP | VIRULENCE | RELA | VIROLOGY | STRINGENT RESPONSE | PSEUDOMONAS | GROWTH | PARASITOLOGY | Klebsiella pneumoniae - drug effects | Salmonella typhimurium - growth & development | Escherichia coli - drug effects | Ligases - genetics | Pseudomonas aeruginosa - growth & development | Biofilms - growth & development | Burkholderia cenocepacia - genetics | Peptide Fragments - pharmacology | Genetic Complementation Test | Microbial Sensitivity Tests | Anti-Bacterial Agents - chemistry | Klebsiella pneumoniae - genetics | Salmonella typhimurium - drug effects | Stress, Physiological - drug effects | Escherichia coli - growth & development | Acinetobacter baumannii - growth & development | Methicillin-Resistant Staphylococcus aureus - genetics | Biofilms - drug effects | Burkholderia cenocepacia - growth & development | Salmonella typhimurium - genetics | Methicillin-Resistant Staphylococcus aureus - drug effects | Ligases - metabolism | Pseudomonas aeruginosa - drug effects | Methicillin-Resistant Staphylococcus aureus - growth & development | Pseudomonas aeruginosa - genetics | Burkholderia cenocepacia - drug effects | Escherichia coli - genetics | Klebsiella pneumoniae - growth & development | Anti-Bacterial Agents - pharmacology | Acinetobacter baumannii - drug effects | Acinetobacter baumannii - genetics | Antibiotics | Genetic aspects | Research | Planktonic bacteria | Microbial mats | Health aspects | Sugars | Monosaccharides | Index Medicus | Medical research | Biofilms | Peptides | Bacteria | Infections | Drug resistance | Stress response | Bacteriology
Journal Article
Antimicrobial Agents and Chemotherapy, ISSN 0066-4804, 05/2012, Volume 56, Issue 5, pp. 2314 - 2325
Classifications Services AAC Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley Reddit... 
IN-VITRO | POLYMORPHONUCLEAR LEUKOCYTES | PSEUDOMONAS-AERUGINOSA VIRULENCE | COMPOUND | ANTIBIOTIC-RESISTANCE | MICROBIOLOGY | PHARMACOLOGY & PHARMACY | CHRONIC WOUNDS | CYSTIC-FIBROSIS | LUNG INFECTION | VIBRIO-HARVEYI | BACTERIAL BIOFILMS | Plant Extracts - chemistry | Biofilms - growth & development | Tobramycin - administration & dosage | Garlic - chemistry | Respiratory Tract Infections - microbiology | Anti-Bacterial Agents - therapeutic use | Disulfides - therapeutic use | Pseudomonas aeruginosa - pathogenicity | Disulfides - pharmacology | Genes, Reporter | Tobramycin - therapeutic use | Virulence Factors - antagonists & inhibitors | Glycolipids - antagonists & inhibitors | Biofilms - drug effects | Quorum Sensing - drug effects | Pseudomonas Infections - drug therapy | Neutrophils - drug effects | Respiratory Tract Infections - drug therapy | Anti-Bacterial Agents - isolation & purification | Pseudomonas aeruginosa - drug effects | Pseudomonas Infections - microbiology | Quorum Sensing - genetics | Drug Synergism | Gene Expression Regulation, Bacterial - drug effects | Animals | Pseudomonas aeruginosa - genetics | Chemical Fractionation | Anti-Bacterial Agents - pharmacology | Mice | Disulfides - isolation & purification | Index Medicus | Drugs | Animal models | Communication systems | quorum sensing | Lung | Antimicrobial agents | virulence factors | Necrosis | Infection | Pathogenicity | Biofilms | DNA microarrays | Leukocytes (polymorphonuclear) | Tobramycin | rhamnolipids | Mechanisms of Action | Physiological Effects
Journal Article
PLoS ONE, ISSN 1932-6203, 04/2015, Volume 10, Issue 4, pp. e0124595 - e0124595
Staphylococcus aureus is a Gram-positive bacterium that has become the leading cause of hospital acquired infections in the US. Repurposing Food and Drug... 
INTRINSIC RESISTANCE | EFFLUX PUMP(S) | CAENORHABDITIS-ELEGANS | EVOLUTION | VIRULENCE FACTORS | PSEUDOMONAS-AERUGINOSA | MULTIDISCIPLINARY SCIENCES | MODEL HOST | MRSA | INHIBITORS | IDENTIFICATION | Oxyclozanide - pharmacology | Cell Survival - drug effects | Enterococcus faecium - drug effects | Microbial Viability - drug effects | Humans | Methicillin-Resistant Staphylococcus aureus - drug effects | Drug Repositioning | Erythrocytes - drug effects | Hep G2 Cells | Microbial Sensitivity Tests | Gram-Negative Bacteria - drug effects | Methicillin-Resistant Staphylococcus aureus - growth & development | Animals | Anthelmintics - pharmacology | Niclosamide - pharmacology | Gram-Negative Bacteria - growth & development | Erythrocytes - cytology | Sheep | Anti-Bacterial Agents - pharmacology | Enterococcus faecium - growth & development | Drug Resistance, Multiple, Bacterial - drug effects | Drugs | Veterinary supplies industry | Staphylococcus aureus infections | Cross infection | Nosocomial infections | Drug resistance | Comparative analysis | Health aspects | Antibacterial agents | Drug approval | Staphylococcus aureus | Klebsiella | Linezolid | Regulatory agencies | Antimicrobial activity | Low concentrations | Laboratories | Toxicity | Liver | Erythrocytes | Daptomycin | Niclosamide | Gram-positive bacteria | Clinical isolates | Genomes | Infections | Vancomycin | Drug development | Kinases | Veterinary medicine | Antiinfectives and antibacterials | Medical schools | Risk factors | Methicillin | Cell growth | Red blood cells | Pseudomonas aeruginosa | Bacteria | Biocompatibility | Pharmaceutical industry | Aerogenes | Staphylococcus infections | Antimicrobial agents | Bacteriology | Studies | Chemotherapy | Hospitals | Infectious diseases | Biofilms | Antibiotics | Hepatocytes | Minimum inhibitory concentration | Index Medicus
Journal Article
PLoS ONE, ISSN 1932-6203, 11/2011, Volume 6, Issue 11, pp. e28291 - e28291
The velvet protein, VeA, is involved in the regulation of diverse cellular processes. In this study, we explored functions of FgVeA in the wheat head blight... 
REDUCED VIRULENCE | VEA | ASPERGILLUS-NIDULANS | BOTRYTIS-CINEREA | APPRESSORIUM TURGOR | MAP KINASE | MULTIDISCIPLINARY SCIENCES | GENE-EXPRESSION | GIBBERELLA-ZEAE | MAGNAPORTHE-GRISEA | SEXUAL DEVELOPMENT | Hyphae - growth & development | Virulence - drug effects | Methyltransferases - metabolism | Spores, Fungal - growth & development | Colony Count, Microbial | Fungicides, Industrial - pharmacology | Gene Expression Regulation, Fungal - drug effects | Sequence Analysis, Protein | Cell Wall - drug effects | Spores, Fungal - drug effects | Gene Deletion | Protein Binding - drug effects | Stress, Physiological - drug effects | Fusarium - genetics | Fusarium - metabolism | Fusarium - pathogenicity | Protein Structure, Tertiary | Methyltransferases - chemistry | Reproduction, Asexual - drug effects | Pigmentation - drug effects | Hyphae - ultrastructure | Drug Resistance, Fungal - drug effects | Fungal Proteins - genetics | Osmosis - drug effects | Fusarium - growth & development | Trichothecenes - biosynthesis | Glycerol - metabolism | Hyphae - metabolism | Spores, Fungal - ultrastructure | Lipid Metabolism - drug effects | Hyphae - drug effects | Fungal Proteins - metabolism | Proteins | Fungicides | Gene expression | Analysis | Germination | Biotechnology | Yeast | Laboratories | Pathogenesis | Genomics | Virulence | Amino acids | Biosynthesis | Genomes | Hydrophobicity | Gene deletion | Kinases | Wheat head blight | Osmotic stress | Deletion mutant | Fungi | Clonal deletion | Metabolites | Iprodione | Fludioxonil | Blight | Deletion | Fusarium | Flowering | Pathogens | Sensitivity analysis | Fusarium graminearum | Cell walls | Serial analysis of gene expression | Glycerol | Deoxynivalenol | Metabolism | Chromatography | Studies | Sensitivity | Mutagenesis | Hyphae | Scientific imaging | Crop diseases | Molecular biology | Wheat | Mass spectrometry | Conidia | Index Medicus
Journal Article
PLoS Pathogens, ISSN 1553-7366, 02/2013, Volume 9, Issue 2, pp. e1003174 - e1003174
HIV-1 reservoirs preclude virus eradication in patients receiving highly active antiretroviral therapy (HAART). The best characterized reservoir is a small,... 
LOW-LEVEL VIREMIA | PLASMA VIREMIA | CD4(+) T-CELLS | MICROBIOLOGY | PERIPHERAL-BLOOD | BLOOD MONONUCLEAR-CELLS | LATENT HIV-1 | INFECTED INDIVIDUALS | VIROLOGY | ACTIVE ANTIRETROVIRAL THERAPY | IN-VIVO | IMMUNODEFICIENCY-VIRUS TYPE-1 | PARASITOLOGY | Proviruses - isolation & purification | Disease Reservoirs - virology | Humans | Middle Aged | DNA, Viral - analysis | Male | Leukocytes, Mononuclear - virology | RNA, Viral - genetics | Proviruses - genetics | Virus Integration - drug effects | Polymerase Chain Reaction | Adult | Female | DNA, Viral - drug effects | Leukocytes, Mononuclear - drug effects | HIV Infections - genetics | HIV Infections - virology | RNA, Viral - analysis | HIV - isolation & purification | Proviruses - growth & development | HIV - growth & development | Antiretroviral Therapy, Highly Active | HIV - genetics | HIV Infections - drug therapy | Aged | DNA, Viral - genetics | RNA, Viral - drug effects | Viral Load - drug effects | Longitudinal Studies | CD4-Positive T-Lymphocytes - drug effects | Physiological aspects | HIV patients | Virulence (Microbiology) | Research | T cells | Health aspects | Plasma | Clinical trials | Statistical methods | Infections | Genomes | Grants | Experiments | Acquired immune deficiency syndrome--AIDS | Lymphocytes | Normal distribution | Human immunodeficiency virus--HIV | Drug therapy | Deoxyribonucleic acid--DNA | Index Medicus | AIDS | HIV | Acquired immune deficiency syndrome | Deoxyribonucleic acid | DNA | Human immunodeficiency virus
Journal Article
Molecular Plant-Microbe Interactions, ISSN 0894-0282, 05/2017, Volume 30, Issue 5, pp. 410 - 422
Vesicle trafficking is an important event in eukaryotic organisms. Many proteins and lipids transported between different organelles or compartments are... 
NUCLEOTIDE EXCHANGE | BIOCHEMISTRY & MOLECULAR BIOLOGY | PLANT INFECTION | PLANT SCIENCES | REDUCED VIRULENCE | TETHERING COMPLEXES | MAGNAPORTHE-ORYZAE | BIOTECHNOLOGY & APPLIED MICROBIOLOGY | LYSOSOME FUSION | RICE BLAST FUNGUS | GIBBERELLA-ZEAE | VACUOLAR MEMBRANE DYNAMICS | RAB GTPASES | Hyphae - growth & development | Virulence - drug effects | Fusarium - drug effects | Guanosine Triphosphate - metabolism | Protein Transport - drug effects | Fungicides, Industrial - pharmacology | Autophagy - drug effects | Endosomes - metabolism | Gene Expression Regulation, Fungal - drug effects | Microtubules - metabolism | Virulence - genetics | Microtubules - drug effects | Spores, Fungal - drug effects | Gene Deletion | Protein Binding - drug effects | Endosomes - drug effects | Genes, Fungal | Stress, Physiological - drug effects | Transport Vesicles - drug effects | Autophagy - genetics | Guanosine Diphosphate - metabolism | Fusarium - genetics | Fusarium - metabolism | Fusarium - pathogenicity | Green Fluorescent Proteins - metabolism | Pigmentation - drug effects | Stress, Physiological - genetics | Endocytosis - drug effects | Subcellular Fractions - metabolism | Two-Hybrid System Techniques | Phenotype | Trichothecenes - metabolism | Hyphae - metabolism | Models, Biological | Spores, Fungal - metabolism | Transport Vesicles - metabolism | Hyphae - drug effects | Fungal Proteins - metabolism | Index Medicus
Journal Article