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PLoS Pathogens, ISSN 1553-7366, 2015, Volume 11, Issue 9, p. e1005142
Pharmacologically-induced activation of replication competent proviruses from latency in the presence of antiretroviral treatment (ART) has been proposed as a... 
ACTIVATION | RNA | PERSISTENCE | CD4(+) T-CELLS | MICROBIOLOGY | VIROLOGY | HISTONE DEACETYLASES | ACTIVE ANTIRETROVIRAL THERAPY | IMMUNODEFICIENCY-VIRUS TYPE-1 | STEM-CELL | INFECTION | PARASITOLOGY | VIRAL RESERVOIR | Follow-Up Studies | Humans | Middle Aged | Antiretroviral Therapy, Highly Active - adverse effects | Male | RNA, Viral - blood | AIDS Vaccines - therapeutic use | Virus Latency - drug effects | AIDS Vaccines - adverse effects | Anti-HIV Agents - administration & dosage | HIV Infections - immunology | Drug Interactions | HIV-1 - physiology | Lymphocytes - immunology | Protein Processing, Post-Translational - drug effects | HIV-1 - isolation & purification | Adult | Anti-HIV Agents - therapeutic use | Female | Depsipeptides - therapeutic use | RNA, Viral - metabolism | Depsipeptides - adverse effects | Biomarkers - metabolism | Lymphocytes - metabolism | HIV-1 - drug effects | Anti-HIV Agents - adverse effects | HIV Infections - virology | Biomarkers - blood | Histones - blood | Acetylation - drug effects | HIV-1 - immunology | Virus Activation - drug effects | Lymphocytes - drug effects | HIV Infections - drug therapy | Histones - metabolism | Infusions, Intravenous | Viral Load - drug effects | Cohort Studies | Depsipeptides - administration & dosage | HIV Infections - metabolism | Studies | Plasma | HIV | Acquired immune deficiency syndrome | Cytokines | Lymphocytes | Curing | AIDS | Infections | Human immunodeficiency virus | Research | Drug therapy
Journal Article
Journal of Clinical Investigation, ISSN 0021-9738, 05/2015, Volume 125, Issue 5, pp. 1901 - 1912
Reversal of HIV-1 latency by small molecules is a potential cure strategy. This approach will likely require effective drug combinations to achieve high levels... 
SUPPRESSIVE ANTIRETROVIRAL THERAPY | MEDICINE, RESEARCH & EXPERIMENTAL | VIRUS REACTIVATION | ACTIVATION | RESERVOIR | IN-VIVO | GENE-EXPRESSION | CD4(+) T-CELLS | HISTONE DEACETYLASE INHIBITORS | NF-KAPPA-B | LIFELONG PERSISTENCE | Anti-HIV Agents - pharmacology | Transcription, Genetic - drug effects | Lymphokines - secretion | Humans | Middle Aged | RNA, Messenger - analysis | Male | Virus Latency - drug effects | Anti-HIV Agents - administration & dosage | HIV-1 - physiology | Phorbol Esters - pharmacology | Adult | Anti-HIV Agents - therapeutic use | Female | CD4-Positive T-Lymphocytes - virology | Drug Evaluation, Preclinical | Bryostatins - pharmacology | HIV-1 - drug effects | Lymphocyte Activation | HIV Infections - virology | Protein Kinase C - drug effects | Cells, Cultured | RNA, Viral - analysis | Virion - metabolism | Azepines - pharmacology | Drug Synergism | Triazoles - pharmacology | CD4-Positive T-Lymphocytes - secretion | HIV Infections - drug therapy | Histone Deacetylase Inhibitors - pharmacology | Disulfiram - pharmacology | CD4-Positive T-Lymphocytes - drug effects | Physiological aspects | Research | RNA | T cells | Drug therapy | HIV infection | Studies | Statistical analysis | Cytokines | Acquired immune deficiency syndrome--AIDS | Lymphocytes | T cell receptors | Mathematical models | Gene expression | HIV | Infectious disease | AIDS
Journal Article
Nature, ISSN 0028-0836, 07/2012, Volume 487, Issue 7408, pp. 482 - 485
Despite antiretroviral therapy, proviral latency of human immunodeficiency virus type 1 (HIV-1) remains a principal obstacle to curing the infection(1).... 
CELLS | ACTIVATION | SUBEROYLANILIDE HYDROXAMIC ACID | MULTIDISCIPLINARY SCIENCES | IN-VIVO | VALPROIC ACID | INFECTION | HISTONE DEACETYLASE INHIBITORS | TYPE-1 | EXPRESSION | PCR | Gene Expression Regulation, Viral - drug effects | Humans | Hydroxamic Acids - adverse effects | Histone Deacetylase Inhibitors - administration & dosage | RNA, Viral - blood | Virus Latency - drug effects | Proviruses - drug effects | HIV-1 - growth & development | Proviruses - genetics | Hydroxamic Acids - administration & dosage | Anti-HIV Agents - therapeutic use | CD4-Positive T-Lymphocytes - virology | Hydroxamic Acids - pharmacology | Biomarkers - metabolism | HIV Infections - blood | Risk Assessment | HIV-1 - drug effects | CD4-Positive T-Lymphocytes - cytology | HIV Infections - virology | RNA, Viral - biosynthesis | CD4-Positive T-Lymphocytes - metabolism | Viremia - drug therapy | HIV-1 - genetics | Proviruses - growth & development | Histones - drug effects | Up-Regulation - drug effects | Acetylation - drug effects | Viremia - virology | HIV Infections - drug therapy | Histone Deacetylase Inhibitors - pharmacology | Histones - metabolism | CD4-Positive T-Lymphocytes - drug effects | Histone Deacetylase Inhibitors - adverse effects | Physiological aspects | Antiviral agents | HIV patients | Health aspects | Vorinostat | Antiretroviral drugs | Plasma | Cell culture | Lymphocytes | Human immunodeficiency virus--HIV | Genomes | Drug therapy | Drug dosages
Journal Article
Journal of Clinical Investigation, ISSN 0021-9738, 11/2009, Volume 119, Issue 11, pp. 3473 - 3486
Journal Article
Nature Medicine, ISSN 1078-8956, 2014, Volume 20, Issue 4, pp. 425 - 429
Journal Article
PLoS Pathogens, ISSN 1553-7366, 07/2015, Volume 11, Issue 7, pp. e1005063 - e1005063
Journal Article
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 5/2014, Volume 111, Issue 19, pp. 7078 - 7083
Journal Article