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1. Vitamin D and the immune system: New perspectives on an old theme
by Hewison, Martin
Endocrinology and Metabolism Clinics of North America, ISSN 0889-8529, 06/2010, Volume 39, Issue 2, pp. 365 - 379
Interaction with the immune system is one of the most well-established nonclassic effects of vitamin D. For many years this was considered to be a... 
Cathelicidin | CYP27b1 | Vitamin D | Regulatory T cells | Toll-like receptor | Macrophage | EXPERIMENTAL AUTOIMMUNE ENCEPHALOMYELITIS | DENDRITIC CELLS | IMMUNOGLOBULIN PRODUCTION | CD4(+) T-CELLS | CATHELICIDIN ANTIMICROBIAL PEPTIDE | INFLAMMATORY-BOWEL-DISEASE | ENDOCRINOLOGY & METABOLISM | ALVEOLAR MACROPHAGES | 1,25-DIHYDROXYVITAMIN D-3 | D-RECEPTOR | IN-VITRO GENERATION | Adaptive Immunity | Antimicrobial Cationic Peptides - immunology | Dendritic Cells - immunology | Humans | Autoimmune Diseases - immunology | 25-Hydroxyvitamin D3 1-alpha-Hydroxylase - genetics | Antigen Presentation - immunology | Immunity, Innate | Crohn Disease - immunology | Tuberculosis - immunology | Animals | B-Lymphocytes - immunology | Vitamin D - immunology | 25-Hydroxyvitamin D3 1-alpha-Hydroxylase - immunology | Immune System | Multiple Sclerosis - immunology | T-Lymphocytes - immunology | Vitamin D - metabolism | Mice | Diabetes Mellitus, Type 1 - immunology | Vitamin D - therapeutic use | Macrophages - immunology
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2. Full Text Propionibacterium acnes Induces an IL-17 Response in Acne Vulgaris that Is Regulated by Vitamin A and Vitamin D
by Agak, George W and Qin, Min and Nobe, Jennifer and Kim, Myung-Hwa and Kim, Jenny and Krutzik, Stephan R and Tristan, Grogan R and Elashoff, David and Garbán, Hermes J
Journal of Investigative Dermatology, ISSN 0022-202X, 02/2014, Volume 134, Issue 2, pp. 366 - 373
Acne vulgaris is the most common skin disorder affecting millions of people worldwide and inflammation resulting from the immune response targeting has a... 
INFLAMMATORY CYTOKINE RESPONSES | GROWTH-FACTOR-BETA | RETINOIC ACID | T(H)17 CELLS | INTERLEUKIN-17 | CIRCULATING TH17 | DIFFERENTIATION | T-CELLS | AUTOIMMUNE ENCEPHALOMYELITIS | TH17 CELLS | DERMATOLOGY | Gram-Positive Bacterial Infections - immunology | Acne Vulgaris - immunology | Humans | Receptors, Interleukin-17 - immunology | Interleukin-17 - immunology | Th1 Cells - immunology | Interleukins - metabolism | Vitamin A - metabolism | CD4-Positive T-Lymphocytes - immunology | Nuclear Receptor Subfamily 1, Group F, Member 1 - metabolism | Receptors, Interleukin - metabolism | Vitamin D - immunology | Interleukins - immunology | Nuclear Receptor Subfamily 1, Group F, Member 3 - metabolism | Th17 Cells - cytology | Receptors, Interleukin-17 - metabolism | Propionibacterium acnes - immunology | Nuclear Receptor Subfamily 1, Group F, Member 3 - immunology | CD4-Positive T-Lymphocytes - microbiology | Nuclear Receptor Subfamily 1, Group F, Member 1 - immunology | Receptors, Interleukin - immunology | CD4-Positive T-Lymphocytes - cytology | Acne Vulgaris - pathology | Gram-Positive Bacterial Infections - pathology | Cell Differentiation - immunology | Interleukin-17 - metabolism | Th1 Cells - microbiology | Th17 Cells - immunology | Th1 Cells - cytology | Th17 Cells - microbiology | Acne Vulgaris - microbiology
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3. Full Text Vitamin D controls T cell antigen receptor signaling and activation of human T cells
by Von Essen, Marina Rode and Kongsbak, Martin and Schjerling, Peter and Olgaard, Klaus and Ødum, Niels and Geisler, Carsten
Nature Immunology, ISSN 1529-2908, 2010, Volume 11, Issue 4, pp. 344 - 349
Phospholipase C (PLC) isozymes are key signaling proteins downstream of many extracellular stimuli. Here we show that naive human T cells had very low... 
PHOSPHOLIPASE C-GAMMA-1 | REQUIREMENTS | IN-VITRO | TCR | IMMUNE-SYSTEM | PHOSPHORYLATION | PROTEIN-KINASE | DIFFERENTIAL ACTIVATION | MEDIATED ACTIVATION | DOWN-REGULATION | IMMUNOLOGY | Signal Transduction - immunology | Lymphocyte Activation - immunology | Phospholipase C gamma - immunology | In Situ Hybridization | Vitamin D - immunology | Receptors, Calcitriol - immunology | Humans | Cells, Cultured | Immunoblotting | Receptors, Antigen, T-Cell - immunology | Enzyme Activation - immunology | Phospholipase C gamma - biosynthesis | Antigen receptors, T cell | Receptors | Vitamin D | Physiological aspects | Calcifediol | Cellular signal transduction | Genetic aspects | Alfacalcidol | Research | T cells
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4. Full Text An update on vitamin D and human immunity
by Hewison, Martin
Clinical Endocrinology, ISSN 0300-0664, 03/2012, Volume 76, Issue 3, pp. 315 - 325
Summary In the last 5 years, there has been a remarkable change in our understanding of the health benefits of vitamin D. The classical actions of vitamin D as... 
EXPERIMENTAL AUTOIMMUNE ENCEPHALOMYELITIS | GROUP-SPECIFIC COMPONENT | BONE-MINERAL DENSITY | MULTIPLE-SCLEROSIS | D-RECEPTOR GENE | ENDOCRINOLOGY & METABOLISM | REGULATORY T-CELLS | D DEFICIENCY | D-BINDING PROTEIN | 1,25-DIHYDROXYVITAMIN D-3 | CIRCULATING 25-HYDROXYVITAMIN D | Immunity, Innate - drug effects | Dendritic Cells - immunology | Humans | Receptors, Calcitriol - metabolism | Immunity, Innate - immunology | Macrophages - metabolism | Models, Immunological | Adaptive Immunity - drug effects | Vitamin D - immunology | Receptors, Calcitriol - immunology | T-Lymphocytes - metabolism | T-Lymphocytes - drug effects | Macrophages - drug effects | T-Lymphocytes - immunology | Vitamin D - administration & dosage | Vitamin D - metabolism | Adaptive Immunity - immunology | Dietary Supplements | Dendritic Cells - metabolism | Macrophages - immunology | Hypertension | Osteoporosis | Calcifediol | Alfacalcidol | Vitamin D | Analysis
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5. Full Text Vitamin D-Directed Rheostatic Regulation of Monocyte Antibacterial Responses
by Adams, John S and Ren, Songyang and Liu, Philip T and Chun, Rene F and Lagishetty, Venu and Gombart, Adrian F and Borregaard, Niels and Modlin, Robert L and Hewison, Martin
The Journal of Immunology, ISSN 0022-1767, 04/2009, Volume 182, Issue 7, pp. 4289 - 4295
The active form of vitamin D, 1,25-dihydroxyvitamin D (1,25(OH)(2)D) enhances innate immunity by inducing the cathelicidin antimicrobial peptide (hCAP). In... 
MYCOBACTERIA | DENDRITIC CELLS | GENE | CATHELICIDIN | HYPOVITAMINOSIS-D | 1,25-DIHYDROXYVITAMIN D-3 | D-RECEPTOR | PREVALENCE | HEALTH | IMMUNOLOGY | CUTTING EDGE | Antimicrobial Cationic Peptides - immunology | 25-Hydroxyvitamin D3 1-alpha-Hydroxylase - biosynthesis | Cathelicidins | Humans | Middle Aged | RNA, Messenger - analysis | Male | Monocytes - metabolism | Monocytes - immunology | Antimicrobial Cationic Peptides - metabolism | Vitamin D - immunology | 25-Hydroxyvitamin D3 1-alpha-Hydroxylase - immunology | Female | Vitamin D Deficiency - immunology | Gene Expression | Enzyme-Linked Immunosorbent Assay | Toll-Like Receptor 1 - metabolism | Cells, Cultured | Toll-Like Receptor 4 - immunology | Toll-Like Receptor 2 - metabolism | Immunity, Innate | Reverse Transcriptase Polymerase Chain Reaction | Toll-Like Receptor 4 - metabolism | Toll-Like Receptor 2 - immunology | Vitamin D - analogs & derivatives | Vitamin D - metabolism | Toll-Like Receptor 1 - immunology | Vitamin D - therapeutic use | Vitamin D Deficiency - metabolism | CYP27b1 | macrophage | toll-like receptor | cathelicidin | vitamin D
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6. Full Text Vitamin effects on the immune system: vitamins A and D take centre stage
by von Andrian, Ulrich H and Iwata, Makoto and Mora, J. Rodrigo
Nature Reviews Immunology, ISSN 1474-1733, 09/2008, Volume 8, Issue 9, pp. 685 - 698
Vitamins are essential constituents of our diet that have long been known to influence the immune system. Vitamins A and D have received particular attention... 
ENDOTHELIUM IN-VIVO | EXPERIMENTAL AUTOIMMUNE ENCEPHALOMYELITIS | BONE-MARROW TRANSPLANTATION | EXPERIMENTAL ALLERGIC ENCEPHALOMYELITIS | REGULATORY T-CELLS | TRANS-RETINOIC ACID | IMMUNOLOGY | BLOOD MONONUCLEAR-CELLS | INTESTINAL DENDRITIC CELLS | DRAINING LYMPH-NODES | VERSUS-HOST DISEASE | Humans | Vitamins - metabolism | Lymphocytes - cytology | Vitamin A - metabolism | Vitamin A - immunology | Animals | Lymphocytes - immunology | Vitamin D - immunology | Vitamins - immunology | Immune System - metabolism | Immunotherapy | Immune System - immunology | Vitamin D - metabolism | Prevention | Vitamin A | Care and treatment | Immune response | Vitamin D | Calcifediol | Inflammation | Research | Alfacalcidol | Health aspects
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7. Full Text Environmental risk factors for type 1 diabetes
by Rewers, Marian, Prof and Ludvigsson, Johnny, Prof and Medicinska fakulteten and Region Östergötland and Barn- och ungdomskliniken i Linköping and Linköpings universitet and Institutionen för klinisk och experimentell medicin and Avdelningen för kliniska vetenskaper and Barn- och kvinnocentrum
Lancet, The, ISSN 0140-6736, 2016, Volume 387, Issue 10035, pp. 2340 - 2348
Summary The incidence of type 1 diabetes has risen considerably in the past 30 years due to changes in the environment that have been only partially... 
Internal Medicine | MEDICINE, GENERAL & INTERNAL | CAPSID PROTEIN VP1 | EARLY WEIGHT-GAIN | HLA-CONFERRED SUSCEPTIBILITY | ISLET AUTOIMMUNITY | CALMETTE-GUERIN VACCINATION | BETA-CELL AUTOIMMUNITY | ENDOPLASMIC-RETICULUM STRESS | GUT MICROBIOTA | ENTEROVIRUS INFECTION | DRINKING-WATER | Toxins, Biological - immunology | Humans | Risk Factors | Breast Feeding | Infant Food | Infant | Growth - immunology | Insulin-Secreting Cells - immunology | RNA - genetics | Fatty Acids, Unsaturated - immunology | Vaccines - adverse effects | Animals | Vitamin D - immunology | Diabetes Mellitus, Type 1 - etiology | Diet | Autoimmunity - immunology | Autoantigens - immunology | Birth Weight - immunology | Environment | Milk - immunology | Diabetes Mellitus, Type 1 - immunology | Hygiene | Autoimmunity | Medical colleges | Type 1 diabetes | Risk factors | Studies | Diabetes | Clinical Medicine | Medical and Health Sciences | Endokrinologi och diabetes | Klinisk medicin | Medicin och hälsovetenskap | Endocrinology and Diabetes
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8. Full Text Vitamin D insufficiency is associated with challenge-proven food allergy in infants
by Allen, Katrina J., MBBS, BMedSc, FRACP, PhD and Koplin, Jennifer J., PhD and Ponsonby, Anne-Louise, MBBS, PhD and Gurrin, Lyle C., PhD and Wake, Melissa, MD, FRACP and Vuillermin, Peter, MBBS, FRACP, PhD and Martin, Pamela, PhD and Matheson, Melanie, PhD and Lowe, Adrian, PhD and Robinson, Marnie, MBBS, FRACP and Tey, Dean, MBBS, FRACP and Osborne, Nicholas J., PhD and Dang, Thanh, BSc and Tina Tan, Hern-Tze, BSc and Thiele, Leone, BA, MNSc and Anderson, Deborah, RN and Czech, Helen, RN and Sanjeevan, Jeeva, MBBS and Zurzolo, Giovanni, BSc and Dwyer, Terence, PhD and Tang, Mimi L.K., MBBS, FRACP, FRCPA, PhD and Hill, David, MBBD, FRACP and Dharmage, Shyamali C., MBBS, MSc, MD, PhD
Journal of Allergy and Clinical Immunology, The, ISSN 0091-6749, 2013, Volume 131, Issue 4, pp. 1109 - 1116.e6
Background Epidemiological evidence has shown that pediatric food allergy is more prevalent in regions further from the equator, suggesting that vitamin D... 
Allergy and Immunology | peanut allergy | Vitamin D | epigenetic | eczema | egg allergy | food allergy | oral food challenge | population | UNITED-STATES | RISK-FACTORS | PREVALENCE | IMMUNOLOGY | RADIATION | CHILDREN | ALLERGY | REGULATORY T-CELLS | BIRTH COHORT | LATITUDE | EXPOSURE | Vitamin D Deficiency - complications | Arachis - adverse effects | Humans | Food Hypersensitivity - blood | Infant | Male | Immunoglobulin E - blood | Milk - adverse effects | Tandem Mass Spectrometry | Eggs - adverse effects | Food Hypersensitivity - immunology | Immunoglobulin E - immunology | Vitamin D - immunology | Vitamin D Deficiency - blood | Chromatography, Liquid | Female | Sesamum - adverse effects | Vitamin D Deficiency - immunology | Skin Tests | Food Hypersensitivity - epidemiology | Australia - epidemiology | Vitamin D - blood | Food Hypersensitivity - complications | Animals | Vitamin D Deficiency - epidemiology | Vitamin D - analogs & derivatives | Food allergy | Calcifediol | Infants | Children | Alfacalcidol | Health aspects | Food allergies | Allergies | Milk
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