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Journal Article
BIOORGANIC & MEDICINAL CHEMISTRY, ISSN 0968-0896, 11/2018, Volume 26, Issue 20, pp. 5555 - 5565
alpha-Tocopherol (alpha-TOH) is the primary lipophilic radical trapping antioxidant in human tissues. Oxidative catabolism of alpha-tocopherol (alpha TOH) is... 
OXIDATION | CHEMISTRY, MEDICINAL | Vitamin E | Oxidative metabolism | alpha-Tocopheryl quinone | BIOCHEMISTRY & MOLECULAR BIOLOGY | CHEMISTRY, ORGANIC | alpha-Tocopherol | Cytochrome P450-4F2 | omega-Hydroxylation
Journal Article
Current Opinion in Plant Biology, ISSN 1369-5266, 06/2015, Volume 25, pp. 123 - 129
Tocopherol (vitamin E) and phylloquinone (vitamin K 1 ) are lipid-soluble antioxidants that can only be synthesized by photosynthetic organisms. These... 
SPINACH-CHLOROPLASTS | PHYLLOQUINONE VITAMIN-K1 | TOCOPHEROL | BIOSYNTHESIS | PRENYLQUINONE METABOLISM | PLASTOQUINONE SYNTHESIS | PLANTS | ARABIDOPSIS | PHOTOSYSTEM-I | LIPOPROTEIN PARTICLES | PLANT SCIENCES
Journal Article
Bioorganic & Medicinal Chemistry, ISSN 0968-0896, 11/2018, Volume 26, Issue 20, pp. 5555 - 5565
α-Tocopherol (α-TOH) is the primary lipophilic radical trapping antioxidant in human tissues. Oxidative catabolism of α-tocopherol (αTOH) is initiated by... 
α-Tocopherol | α-Tocopheryl quinone | Cytochrome P450-4F2 | Vitamin E | Oxidative metabolism | ω-Hydroxylation | Index Medicus
Journal Article
Journal Article
Toxicology in Vitro, ISSN 0887-2333, 04/2017, Volume 40, pp. 124 - 133
The expression of CYP4F2, a form of cytochrome P-450 with proposed role in α-tocopherol and long-chain fatty acid metabolism, was explored in HepG2 and HepaRG... 
α-Tocopherol | Alcohol liver disease | Ethanol | CYP4F2 | SREBP-1 | PPAR-γ | ACID | EPOXIDE HYDROLASE | alpha-Tocopherol | HUMAN SERUM | PPAR-gamma | NONALCOHOLIC FATTY LIVER | IN-VITRO | CYTOCHROME-P450 METABOLISM | HEPG2 CELLS | CARDIOVASCULAR-DISEASE | TOXICOLOGY | EXPRESSION | INDUCED HEPATOTOXICITY | Cell Line | Cell Survival - drug effects | Reactive Oxygen Species - metabolism | Ethanol - toxicity | Antioxidants - metabolism | Humans | Cells, Cultured | Cytochrome P-450 Enzyme System - metabolism | Hepatocytes - metabolism | PPAR gamma - metabolism | RNA, Messenger - metabolism | Hep G2 Cells | Cytochrome P-450 Enzyme System - genetics | Cytochrome P-450 Enzyme Inhibitors - toxicity | alpha-Tocopherol - metabolism | Hepatocytes - drug effects | Sterol Regulatory Element Binding Protein 1 - metabolism | Alcohol, Denatured | Cytochrome P-450 | Physiological aspects | Tocopherols | Alcohol | Gene expression | Fatty acids | Liver | Genes | Cytochrome | Regulators | Reactive oxygen species | Transcription | Toxicity | Gene regulation | Cytotoxicity | Biosynthesis | Proteins | Time dependence | Toxicology | Vitamin E | Sterol regulatory element-binding protein | Hydroxylase | Extracellular signal-regulated kinase | Pharmacology | Metabolism | Hepatocytes | Isoforms | Cytochromes | Catabolism | Peroxisome proliferator-activated receptors | Tocopherol | Index Medicus
Journal Article
Biomaterials, ISSN 0142-9612, 2009, Volume 30, Issue 19, pp. 3297 - 3306
Abstract Four systems of nanoparticles of biodegradable polymers were developed in this research for oral delivery of anticancer drugs with Docetaxel used as a... 
Advanced Basic Science | Dentistry | Anticancer drugs | Medical clay | Cancer nanotechnology | Drug delivery device | Oral chemotherapy | Biodegradable polymers | MATERIALS SCIENCE, BIOMATERIALS | VITAMIN-E-TPGS | PACLITAXEL TAXOL(R) | CANCER-CHEMOTHERAPY | VITRO DRUG-RELEASE | ENGINEERING, BIOMEDICAL | CELLULAR UPTAKE | IN-VITRO | CYCLOSPORINE-A | NEW-CONCEPT CHEMOTHERAPY | Coumarins - metabolism | Thiazoles - metabolism | Nanoparticles - chemistry | Antioxidants - metabolism | Humans | Vitamin E - analogs & derivatives | Male | Antineoplastic Agents - therapeutic use | Taxoids - metabolism | Antineoplastic Agents - administration & dosage | Drug Carriers - chemistry | Drug Delivery Systems | Antineoplastic Agents - metabolism | Taxoids - therapeutic use | Bentonite - chemistry | Polyglycolic Acid - metabolism | Bentonite - metabolism | Cell Line | Drug Carriers - metabolism | Lactic Acid - chemistry | Administration, Oral | Lactic Acid - metabolism | Drug Therapy | Rats | Rats, Sprague-Dawley | Neoplasms - drug therapy | Particle Size | Taxoids - administration & dosage | Animals | Polyglycolic Acid - chemistry | Vitamin E - metabolism | Animal experimentation | Clay | Chemotherapy | Biological products | Adsorption | Montmorillonite | Polyethylene glycol | Vitamin E | Analysis | Docetaxel | Cancer | Index Medicus
Journal Article
Free Radical Biology and Medicine, ISSN 0891-5849, 11/2017, Volume 112, pp. 308 - 317
Journal Article
Journal Article
Angewandte Chemie International Edition, ISSN 1433-7851, 05/2016, Volume 55, Issue 20, pp. 6023 - 6027
Synthetic biology has enabled the production of many value‐added chemicals via microbial fermentation. However, the problem of low product titers from... 
synthetic biology | catalysis | metabolism | sustainable chemistry | micelles | ROOM-TEMPERATURE | BACTERIA | TOLERANCE | SOLVENT-IMPREGNATED RESINS | CHEMISTRY, MULTIDISCIPLINARY | AMPHIPHILE | SURFACTANT | CHEMICALS | MIYAURA CROSS-COUPLINGS | WATER | Metabolic Engineering | Green Chemistry Technology | Microscopy, Electron, Transmission | Arabidopsis - enzymology | Phenylalanine - metabolism | Styrene - metabolism | Biocompatible Materials - chemistry | Phenylalanine Ammonia-Lyase - metabolism | Arabidopsis Proteins - metabolism | Biocompatible Materials - chemical synthesis | Styrene - chemistry | Phenylalanine - chemistry | Micelles | Escherichia coli - metabolism | Saccharomyces cerevisiae - enzymology | Carboxy-Lyases - metabolism | Vitamin E - chemistry | Fungal Proteins - metabolism | Surface active agents | Transition metal compounds | Metal catalysts | Escherichia coli | Cyclopropane compounds | Green technology | Physiological aspects | Permeability | Catalysis | Fermentation | Metabolism | Biotechnology | Fluctuations | Catalysts | Membrane permeability | Flux | Surfactants | Sustainable yield | Renewable resources | Molecular chains | Organic chemistry | Metabolic flux | Chemistry | Microorganisms | Vitamin E | Styrene | Metabolic engineering | Biocompatibility | Tocopherol | Pollutants | Recombinant | Index Medicus | Synthetic Biology | Sustainable Chemistry
Journal Article
New Phytologist, ISSN 0028-646X, 01/2018, Volume 217, Issue 1, pp. 245 - 260
Photosynthetic organisms such as plants, algae and some cyanobacteria synthesize tocochromanols, a group of compounds that encompasses tocopherols and... 
diacylglycerol acyltransferase1 | wri1 | vitamin E | nutrigenomics | dgat1 | tocopherol | wrinkled1 | tocomonoenol | wrinkled1 (wri1) | diacylglycerol acyltransferase1 (dgat1) | PATHWAYS | PROTEIN | PLANT SCIENCES | VITAMIN-E BIOFORTIFICATION | ALPHA-TOCOMONOENOL | ISOPRENOID BIOSYNTHESIS | THALIANA | TOCOPHEROL BIOSYNTHESIS | SEED OIL | PLANTS | CHLOROPHYLL | Arabidopsis Proteins - genetics | Arabidopsis - enzymology | Intramolecular Transferases - genetics | Seeds - genetics | Tocotrienols - metabolism | Alkyl and Aryl Transferases - metabolism | Seeds - enzymology | Vitamin E - analogs & derivatives | Lipid Metabolism | Biosynthetic Pathways | Transcription Factors - genetics | Tocopherols - metabolism | Chromans - metabolism | Arabidopsis - genetics | Arabidopsis Proteins - metabolism | Intramolecular Transferases - metabolism | Transcription Factors - metabolism | Diacylglycerol O-Acyltransferase - genetics | Diglycerides - metabolism | Alkyl and Aryl Transferases - genetics | Vitamin E - metabolism | Diacylglycerol O-Acyltransferase - metabolism | Acyl Coenzyme A - metabolism | Arabidopsis thaliana | Quantitative genetics | Phosphates | Plant genetics | Tocopherols | Physiological aspects | Lipids | Genetic engineering | Plants | Seeds | Genes | Algae | Diacylglycerol | Transgenic | Genomes | Identification | Plants (organisms) | Biosynthesis | Metabolism | Vitamins | Mutants | Vitamin E | Cyanobacteria | Genetics | Tocopherol | Photosynthesis | Index Medicus
Journal Article