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Journal Article
PloS one, ISSN 1932-6203, 2018, Volume 13, Issue 10, p. e0205292
Purpose To investigate the immunopathogenesis of endophthalmitis, and determine if cytokine profiles could serve as biomarkers of disease severity in... 
UVEITIS | MULTIDISCIPLINARY SCIENCES | PERSPECTIVES | INFLAMMATORY MEDIATORS | Interleukin-8 - genetics | Prospective Studies | Retinal Detachment - pathology | Humans | Middle Aged | Endophthalmitis - immunology | Child, Preschool | Endophthalmitis - metabolism | Interleukin 1 Receptor Antagonist Protein - genetics | Male | Chemokine CXCL1 - genetics | Diabetic Retinopathy - pathology | Endophthalmitis - pathology | Gram-Negative Bacteria - isolation & purification | Granulocyte Colony-Stimulating Factor - genetics | Diabetic Retinopathy - diagnosis | Vitreous Body - metabolism | Bacterial Infections - immunology | Retinal Detachment - diagnosis | Aged, 80 and over | Adult | Endophthalmitis - diagnosis | Female | Child | Retinal Detachment - metabolism | Biomarkers - metabolism | Severity of Illness Index | Gene Expression | Diabetic Retinopathy - immunology | Interleukin 1 Receptor Antagonist Protein - immunology | Interleukin-6 - genetics | Retinal Detachment - immunology | Visual Acuity | Diabetic Retinopathy - metabolism | Chemokine CXCL1 - immunology | Bacterial Infections - pathology | Adolescent | Interleukin-6 - immunology | Gram-Positive Bacteria - isolation & purification | Vitreous Body - immunology | Vitreous Body - pathology | Aged | Bacterial Infections - diagnosis | Granulocyte Colony-Stimulating Factor - immunology | Interleukin-8 - immunology | Bacterial Infections - metabolism | Usage | Care and treatment | Cytokines | Endophthalmitis | Genetic aspects | Diagnosis | Research | Biological markers | Gene expression | Health aspects | Diabetic retinopathy | Medical research | Analysis | Medicine, Experimental | Transforming growth factors | Cataracts | Therapy | Immunoassay | Correlation | Retinopathy | Microbiology | Pathogenesis | Retina | Infections | Interleukin 1 receptors | Epidemiology | Acuity | Interleukin 6 | Granulocyte colony-stimulating factor | Interleukin 1 | Immunopathogenesis | IP-10 protein | Tumor necrosis factor-TNF | Growth factors | Interleukin 8 | Culture | Interleukin 1 receptor antagonist | Diabetes mellitus | Visual acuity | Inflammation | Tumor necrosis factor-α | IL-1β | Patients | Empirical analysis | Infectious diseases | Antibiotics | γ-Interferon | Biomarkers | Chemokines | Monocyte chemoattractant protein 1
Journal Article
Human Immunology, ISSN 0198-8859, 2014, Volume 75, Issue 6, pp. 570 - 577
Journal Article
Journal of International Medical Research, ISSN 0300-0605, 12/2016, Volume 44, Issue 6, pp. 1403 - 1413
Objective To quantify T helper (Th)17 cells and determine interleukin (IL)-17A levels in peripheral blood mononuclear cell (PBMC) culture and vitreous fluid... 
peripheral blood mononuclear cells | type 2 diabetes mellitus | Diabetic retinopathy | interleukin-17A | T helper 17 cells | MEDICINE, RESEARCH & EXPERIMENTAL | POPULATION | MECHANISMS | PREVALENCE | PATHOGENESIS | PROTEIN-1 | INTERLEUKIN-17 | INSULIN-RESISTANCE | VITREORETINOPATHY | PHARMACOLOGY & PHARMACY | INFLAMMATORY CYTOKINES | EXPRESSION | Retinal Perforations - immunology | Diabetes Mellitus, Type 2 - genetics | Humans | Macular Edema - pathology | Middle Aged | Interleukin-17 - immunology | Epiretinal Membrane - genetics | Macular Edema - immunology | Male | Glycated Hemoglobin A - immunology | Diabetic Retinopathy - pathology | Case-Control Studies | Retinal Perforations - genetics | Vitreous Body - metabolism | Diabetes Mellitus, Type 2 - immunology | Leukocytes, Mononuclear - immunology | Female | Retinal Perforations - surgery | Vitrectomy | Epiretinal Membrane - surgery | Macular Edema - genetics | Diabetes Mellitus, Type 2 - surgery | Th17 Cells - pathology | Vitreous Body - surgery | Body Mass Index | Epiretinal Membrane - immunology | Gene Expression | Diabetic Retinopathy - immunology | Interleukin-17 - genetics | Diabetic Retinopathy - surgery | Diabetic Retinopathy - genetics | Leukocytes, Mononuclear - pathology | Macular Edema - surgery | Epiretinal Membrane - pathology | Th17 Cells - immunology | Vitreous Body - immunology | Vitreous Body - pathology | Aged | Diabetes Mellitus, Type 2 - pathology | Primary Cell Culture | Retinal Perforations - pathology | Glycated Hemoglobin A - genetics | Research Reports
Journal Article
PloS one, ISSN 1932-6203, 2015, Volume 10, Issue 9, p. e0137358
Macrophages are involved in low-grade inflammation in diabetes, and play pathogenic roles in proliferative diabetic retinopathy (PDR) by producing... 
VEGF | MULTIDISCIPLINARY SCIENCES | IL-17 | INTERLEUKIN-31 | EXPRESSION | T-CELLS | ANGIOGENIC FACTORS | IL-31 | Tumor Necrosis Factor-alpha - metabolism | Eye - pathology | Inflammation - pathology | Humans | Middle Aged | Male | Diabetic Retinopathy - pathology | Inflammation - metabolism | Retinal Perforations - metabolism | Th17 Cells - metabolism | Vitreous Body - metabolism | Sarcoidosis - immunology | Tumor Necrosis Factor-alpha - immunology | Aged, 80 and over | Adult | Female | Vitrectomy | Macrophages - immunology | Th2 Cells - pathology | Cytokines - blood | Cytokines - immunology | Uveitis - metabolism | Eye - metabolism | Diabetic Retinopathy - immunology | Cytokines - metabolism | Macrophages - pathology | Inflammation - immunology | Diabetic Retinopathy - surgery | Immunity, Innate | Th2 Cells - metabolism | Diabetic Retinopathy - blood | Macrophages - metabolism | Th17 Cells - immunology | Vitreous Body - immunology | Vitreous Body - pathology | Aged | Retinal Perforations - pathology | Inflammation - surgery | Sarcoidosis - metabolism | Uveitis - pathology | Sarcoidosis - pathology | Diabetic retinopathy | Cytokines | Physiological aspects | Development and progression | Genetic aspects | Research | T cells | Retinopathy | Pathogenesis | Helper cells | Homeostasis | Interleukin 22 | Retina | Interleukin 23 | Lymphocytes T | Macrophages | Dermatitis | Hemorrhage | Inflammatory diseases | Interleukin 6 | Interleukin 4 | Lymphocytes | Quality | Surgery | Uveitis | Interleukin 21 | Immune response | Sarcoidosis | Review boards | Diabetes mellitus | Inflammation | Tumor necrosis factor-α | Patients | Allergies | γ-Interferon | Interleukin 10 | Ligands | Infiltration | Interferon | Diabetes
Journal Article
PloS one, ISSN 1932-6203, 2009, Volume 4, Issue 12, pp. e8158 - e8158
Inflammation affects the formation and the progression of various vitreoretinal diseases. We performed a comprehensive analysis of inflammatory immune... 
C-C CHEMOKINES | INTRAVITREAL TRIAMCINOLONE | PROLIFERATIVE DIABETIC-RETINOPATHY | VITREOUS FLUID | MACULAR EDEMA | MULTIDISCIPLINARY SCIENCES | MULTIPLEX BEAD ANALYSIS | RETINAL VEIN OCCLUSION | MONOCYTE CHEMOTACTIC PROTEIN-1 | NF-KAPPA-B | ENDOTHELIAL GROWTH-FACTOR | Vitreoretinopathy, Proliferative - blood | Retinal Diseases - immunology | Humans | Middle Aged | Retinal Diseases - blood | Male | Diabetic Retinopathy - pathology | Retinal Vein Occlusion - pathology | Inflammation Mediators - metabolism | Retinal Diseases - pathology | Female | Cytokines - blood | Diabetic Retinopathy - immunology | Retinal Vein Occlusion - immunology | Vitreoretinopathy, Proliferative - pathology | Inflammation Mediators - blood | Solubility | Vascular Endothelial Growth Factor A - blood | Vitreoretinopathy, Proliferative - immunology | Retinal Vein Occlusion - blood | Diabetic Retinopathy - blood | Models, Biological | Vitreous Body - immunology | Vitreous Body - pathology | Aged | Diabetic retinopathy | Development and progression | Inflammation | Interleukins | Vascular endothelial growth factor | Analysis | Occlusion | Multiplexing | Membranes | Correlation | Retinopathy | Pathogenesis | Interleukin | Retina | Interleukin 6 | Proteins | Angiogenesis | Ischemia | Granulocytes | Tumor necrosis factor-TNF | Growth factors | Interleukin 8 | Edema | Factor analysis | Cytokines | Diabetes mellitus | Patients | Diseases | Detachment | Correlation analysis | Monocyte chemoattractant protein | Medical prognosis | Photoreceptors | Hypoxia | Diabetes | Chemokines | Monocyte chemoattractant protein 1 | Apoptosis
Journal Article
Journal Article
Clinical and experimental immunology, ISSN 0009-9104, 2015, Volume 181, Issue 2, pp. 338 - 342
Journal Article
American Journal of Physiology - Endocrinology and Metabolism, ISSN 0193-1849, 10/2014, Volume 307, Issue 8, pp. E695 - E702
Ocular ischemic microenvironment plays a critical role in the progression of diabetic retinopathy (DR). In this study, we investigated the effect of vitreous... 
Vitreous | Aqueous | Proliferative diabetic retinopathy | CD34 | Progenitor cells | STEM-CELLS | PHYSIOLOGY | ANGIOGENESIS | THROMBOSPONDIN-1 | TISSUE INHIBITORS | progenitor cells | MICROVASCULAR ENDOTHELIAL-CELLS | UP-REGULATES ANGIOPOIETIN-2 | IN-VITRO | CD34(+) | ENDOCRINOLOGY & METABOLISM | vitreous | RETINOPATHY | PROMOTES ADHESION | TNF-ALPHA | aqueous | proliferative diabetic retinopathy | Platelet Factor 4 - chemistry | Retina - metabolism | Antigens, CD34 - metabolism | Humans | Middle Aged | Platelet Factor 4 - agonists | Eye Proteins - chemistry | Nerve Growth Factors - metabolism | Retina - immunology | Diabetic Retinopathy - pathology | Eye Proteins - agonists | Serpins - chemistry | Aqueous Humor - immunology | Adult Stem Cells - immunology | Neovascularization, Pathologic - pathology | Aqueous Humor - metabolism | Peptide Mapping | Vitreous Body - metabolism | Bone Marrow Cells - immunology | Adult | Neovascularization, Pathologic - immunology | Adult Stem Cells - pathology | Endothelin-1 - chemistry | Adult Stem Cells - cytology | Diabetic Retinopathy - immunology | Serpins - agonists | Serpins - metabolism | Bone Marrow Cells - cytology | Endothelin-1 - metabolism | Vitreoretinopathy, Proliferative - pathology | Bone Marrow Cells - pathology | Cells, Cultured | Nerve Growth Factors - chemistry | Vitreoretinopathy, Proliferative - immunology | Endothelin-1 - agonists | Vitreoretinopathy, Proliferative - metabolism | Chemotaxis | Nerve Growth Factors - agonists | Diabetic Retinopathy - metabolism | Adult Stem Cells - metabolism | Eye Proteins - metabolism | Vitreous Body - immunology | Aged | Neovascularization, Pathologic - metabolism | Platelet Factor 4 - metabolism | Nitric Oxide - metabolism | Retina - pathology | Bone Marrow Cells - metabolism
Journal Article
Journal Article
Molecular Vision, ISSN 1090-0535, 10/2011, Volume 17, Issue 276, pp. 2552 - 2563
Journal Article