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1. Full Text Effect of intralaryngeal muscle synkinesis on perception of voice handicap in patients with unilateral vocal fold paralysis
by Lin, R. Jun and Munin, Michael C and Rosen, Clark A and Smith, Libby J
The Laryngoscope, ISSN 0023-852X, 07/2017, Volume 127, Issue 7, pp. 1628 - 1632
Objectives/Hypothesis: Intralaryngeal muscle synkinesis associated with unilateral vocal fold paralysis (UVFP) is thought to preserve thyroarytenoid-lateral... 
LEMG | laryngeal electromyophgray | voice outcome | voice handicap | vocal fold paralysis | vocal cord paralysis | Voice | dysphonia | MEDICINE, RESEARCH & EXPERIMENTAL | CORD | INNERVATION | EXTENSION | INJECTION MEDIALIZATION | ELECTROMYOGRAPHY | OTORHINOLARYNGOLOGY | LARYNGOPLASTY | SUPERIOR LARYNGEAL NERVE | Vocal Cords - drug effects | Muscle Tonus - physiology | Off-Label Use | Vocal Cords - physiopathology | Humans | Middle Aged | Male | Injections, Intramuscular | Phonation - physiology | Patient Satisfaction | Vocal Cord Paralysis - drug therapy | Adult | Female | Laryngeal Muscles - physiopathology | Nimodipine - administration & dosage | Vocal Cord Paralysis - physiopathology | Vocal Cord Paralysis - psychology | Aged | Biocompatible Materials - administration & dosage | Electromyography | Retrospective Studies | Voice Quality - physiology | Medicine, Experimental | Medical research | Care and treatment | Paralysis
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2. Full Text Photodynamic therapy induces antifibrotic alterations in primary human vocal fold fibroblasts
by Zhang, Chi and Wang, Jiajia and Chou, Adriana and Gong, Ting and Devine, Erin E and Jiang, Jack J
The Laryngoscope, ISSN 0023-852X, 09/2018, Volume 128, Issue 9, pp. E323 - E331
Objectives/Hypothesis: Photodynamic therapy (PDT) is a promising treatment modality for laryngeal dysplasia, early-stage carcinoma, and papilloma, and was... 
vocal fold | Fibroblast | antifibrotic | extracellular matrix | photodynamic | MEDICINE, RESEARCH & EXPERIMENTAL | AMINOLEVULINIC ACID | TGF-BETA | HEPATOCYTE GROWTH-FACTOR | SCAR | GUIDELINES | PHENOTYPE | IN-VITRO | OTORHINOLARYNGOLOGY | TRANSFORMING GROWTH-FACTOR-BETA-1 | EXTRACELLULAR-MATRIX | MYOFIBROBLAST DIFFERENTIATION | Carcinoma - drug therapy | Vocal Cords - drug effects | Vocal Cords - pathology | Photochemotherapy - methods | Humans | Middle Aged | Transforming Growth Factor beta1 - metabolism | Male | Fibroblasts - pathology | Laryngeal Neoplasms - pathology | Dose-Response Relationship, Drug | Cell Movement - drug effects | Collagen - drug effects | Cell Differentiation - drug effects | Fibroblasts - drug effects | Fibrosis | Laryngeal Neoplasms - drug therapy | Cicatrix - pathology | Carcinoma - pathology | Wound Healing - drug effects | Extracellular Matrix Proteins - metabolism | Enzymes | Dysplasia | Analysis | Collagen | Bone morphogenetic proteins | Transforming growth factors | Photochemotherapy | Enzyme-linked immunosorbent assay | Cancer
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3. Full Text The Effects of Exposure to Environmental Cigarette Smoke on the Vocal Folds of Rats
by Babalık, Mahmut and Topaloğlu, İlhan and Saltürk, Ziya and Berkiten, Güler and Atar, Yavuz and Tutar, Belgin and Baş, Şenol
Journal of Voice, ISSN 0892-1997, 11/2018, Volume 32, Issue 6, pp. 652 - 654
This study aimed to investigate histopathologically and immunohistochemically the effects of environmental smoke on the vocal folds. This study examined 20... 
Cigarette | Environmental smoke | Larynx | Immunohistochemical | Rat | AUDIOLOGY & SPEECH-LANGUAGE PATHOLOGY | PROLIFERATION | P53 | PHARYNX | KI-67 | OTORHINOLARYNGOLOGY | GRADE | ESOPHAGEAL CANCER | KI67 | EXPRESSION | Vocal Cords - drug effects | Vocal Cords - pathology | Metaplasia | Animals | Tobacco Smoke Pollution - adverse effects | Rats, Wistar | Time Factors | Hyperplasia | Inhalation Exposure | Ki-67 Antigen - metabolism | Cell Proliferation - drug effects | Vocal Cords - metabolism | Smoking
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4. Full Text Functional remodeling after vocal fold injury by small intestinal submucosa gel containing hepatocyte growth factor
by Choi, Jeong-Seok and Lee, Songyi and Kim, Da Yeon and Kim, Young-Mo and Kim, Moon Suk and Lim, Jae-Yol
Biomaterials, ISSN 0142-9612, 2014, Volume 40, pp. 98 - 106
Abstract A biomaterial derived from porcine small intestinal submucosa (SIS) was used in smart drug delivery and tissue remodeling. SIS suspensions were easily... 
Advanced Basic Science | Dentistry | Extracellular matrix | Wound healing | Biomimetic materials | Hepatocyte growth factor | Vocal folds | MATERIALS SCIENCE, BIOMATERIALS | CANINE MODEL | ENGINEERING, BIOMEDICAL | RECONSTRUCTION | BIOLOGIC SCAFFOLD | RELEASE | BOVINE ACELLULAR SCAFFOLD | MESENCHYMAL STEM-CELLS | FIBROBLASTS | LARYNGEAL INJECTION | DELIVERY-SYSTEM | EXTRACELLULAR-MATRIX | Immunohistochemistry | Vocal Cords - drug effects | Rabbits | Vocal Cords - physiopathology | Hepatocyte Growth Factor - administration & dosage | Vocal Cords - injuries | Extracellular Matrix - metabolism | Elastic Modulus - drug effects | Hepatocyte Growth Factor - pharmacology | Intestine, Small - physiology | Animals | Biomechanical Phenomena - drug effects | Cicatrix - pathology | Endoscopy | Delayed-Action Preparations | Sus scrofa | Rheology - drug effects | Gels - pharmacology | Biomechanics | Drugs | Public television | Drug delivery systems | Biological products | Analysis | Collagen | Vehicles | Surgical implants | Biomedical materials | Remodeling | Growth factors | Injuries | Biomaterials
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5. Full Text Acoustic speech analysis of patients with decompensated heart failure: A pilot study
by Murton, Olivia M and Hillman, Robert E and Mehta, Daryush D and Semigran, Marc and Daher, Maureen and Cunningham, Thomas and Verkouw, Karla and Tabtabai, Sara and Steiner, Johannes and Dec, G. William and Ausiello, Dennis
The Journal of the Acoustical Society of America, ISSN 0001-4966, 10/2017, Volume 142, Issue 4, pp. EL401 - EL407
This pilot study used acoustic speech analysis to monitor patients with heart failure (HF), which is characterized by increased intracardiac filling pressures... 
ACOUSTICS | AUTOMATIC DETECTION | AUDIOLOGY & SPEECH-LANGUAGE PATHOLOGY | DYSPHONIA SEVERITY | FRAMEWORK | PROTOCOL | INDEX | Predictive Value of Tests | Vocal Cords - physiopathology | Humans | Middle Aged | Speech Production Measurement | Heart Failure - physiopathology | Male | Acoustics | Voice Disorders - diagnosis | Aged, 80 and over | Female | Heart Failure - diagnosis | Voice Disorders - physiopathology | Vocal Cords - drug effects | Voice Disorders - etiology | Heart Failure - complications | Voice Quality - drug effects | Phonation - drug effects | Treatment Outcome | Edema - drug therapy | Lung - physiopathology | Speech Acoustics | Edema - diagnosis | Heart Failure - drug therapy | Voice Disorders - drug therapy | Edema - etiology | Pilot Projects | Diuretics - therapeutic use | Aged | Edema - physiopathology | Respiration | Jasa Express Letters
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6. Full Text Effect of high‐dose vocal fold injection of cidofovir and bevacizumab in a porcine model
by Ahmed, Mostafa. M and Connor, Matthew. P and Palazzolo, Mitzi and Thompson, Michelle E and Lospinoso, Josh and O'Connor, Peter and Howard, N. Scott and Maturo, Stephen. C
The Laryngoscope, ISSN 0023-852X, 03/2017, Volume 127, Issue 3, pp. 671 - 675
Objectives: Perform a follow-up study to investigate the histologic impact of high-dose intralaryngeal cidofovir injections in porcine vocal cords, either... 
cidofovir | bevacizumab | Recurrent respiratory papillomatosis | MEDICINE, RESEARCH & EXPERIMENTAL | LARYNGES | OTORHINOLARYNGOLOGY | NATIONAL REGISTRY | PIG | Immunohistochemistry | Cytosine - analogs & derivatives | Bevacizumab - adverse effects | Humans | Cytosine - administration & dosage | Laryngeal Neoplasms - pathology | Dose-Response Relationship, Drug | Injections, Intralesional | Sensitivity and Specificity | Laryngeal Neoplasms - drug therapy | Papilloma - pathology | Drug Therapy, Combination | Odds Ratio | Disease Models, Animal | Papilloma - drug therapy | Vocal Cords - drug effects | Vocal Cords - pathology | Cytosine - adverse effects | Bevacizumab - administration & dosage | Drug Administration Schedule | Organophosphonates - adverse effects | Random Allocation | Organophosphonates - administration & dosage | Animals | Biopsy, Needle | Sus scrofa | Antimitotic agents | Dosage and administration | Antineoplastic agents | Swine
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7. Full Text The Effects of the Menstrual Cycle on Vibratory Characteristics of the Vocal Folds Investigated With High-Speed Digital Imaging
by Kunduk, Melda and Vansant, Mathew B and Ikuma, Takeshi and McWhorter, Andrew
Journal of Voice, ISSN 0892-1997, 2017, Volume 31, Issue 2, pp. 182 - 187
Summary Objectives This study investigated the effect of menstrual cycle on vocal fold vibratory characteristics in young women using high-speed digital... 
Otolaryngology | Vocal fold vibration | Birth control | Menstrual cycle | Voice | High-speed videoendoscopy | HORMONE-RECEPTORS | PREMENSTRUAL-SYNDROME | VOICE QUALITY | VIDEOENDOSCOPY | FEMALE VOICE | IMPACT | OTORHINOLARYNGOLOGY | ORAL-CONTRACEPTIVES | Vocal Cords - drug effects | Predictive Value of Tests | Laryngoscopy - methods | Vibration | Humans | Voice Quality - drug effects | Contraceptives, Oral, Hormonal - administration & dosage | Image Interpretation, Computer-Assisted | Phonation - drug effects | Vocal Cords - physiology | Vocal Cords - diagnostic imaging | Young Adult | Biomechanical Phenomena | Time Factors | Video Recording | Adult | Female | Menstrual Cycle - drug effects | Investigations | Menstruation
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8. Full Text Safety and short-term outcomes of basic fibroblast growth factor injection for sulcus vocalis
by Kanazawa, Takeharu and Kazuya, Kurakami and Ujimoto, Konomi and Daigo, Komazawa and Kiyoshi, Misawa and Shoichiro, Imayoshi and Yusuke, Watanabe
Acta Oto-Laryngologica, ISSN 0001-6489, 11/2018, Volume 138, Issue 11, pp. 1014 - 1019
Background: Sulcus vocalis (SV) is characterized by the appearance of a groove and fibrotic changes in the vocal fold mucosa and an often irrevocable loss of... 
injection therapy | maximum phonation time | sulcus vocalis | Basic fibroblast growth factor | office procedure | Voice Handicap Index | FOLD SCAR | CORD | OTORHINOLARYNGOLOGY | FASCIA | Vocal Cords - drug effects | Vocal Cords - pathology | Prospective Studies | Drug Administration Schedule | Follow-Up Studies | Humans | Middle Aged | Voice Quality - drug effects | Hospitals, University | Voice Disorders - pathology | Male | Treatment Outcome | Fibroblast Growth Factor 2 - administration & dosage | Voice Disorders - drug therapy | Dose-Response Relationship, Drug | Analysis of Variance | Time Factors | Injections, Intralesional | China | Patient Safety | Adult | Female | Aged
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9. Full Text Abnormal vocal cord movement treated with botulinum toxin in patients with asthma resistant to optimised management
by Baxter, Malcolm and Uddin, Nizam and Raghav, Sanjay and Leong, Paul and Low, Kathy and Hamza, Kais and Holmes, Peter W and Hamilton, Garun and Thyagarajan, Dominic and Lau, Ken and Bardin, Philip G
Respirology, ISSN 1323-7799, 05/2014, Volume 19, Issue 4, pp. 531 - 537
See Editorial, page 467 Abnormal vocal cord movement may contribute to refractory asthma and temporary partial paralysis with botulinum toxin may be an... 
botulinum toxin | vocal cord dysfunction | asthma | STATEMENT | AIRWAY | MOTION | RESPIRATORY SYSTEM | DYSFUNCTION | DYSTONIA | Vocal Cords - physiopathology | Vocal Cord Dysfunction - drug therapy | Anti-Asthmatic Agents - therapeutic use | Humans | Middle Aged | Tomography, X-Ray Computed - methods | Male | Vocal Cord Dysfunction - complications | Acetylcholine Release Inhibitors - administration & dosage | Acetylcholine Release Inhibitors - adverse effects | Female | Botulinum Toxins - adverse effects | Botulinum Toxins - administration & dosage | Drug Resistance | Asthma - diagnosis | Vocal Cords - drug effects | Asthma - physiopathology | Vocal Cord Dysfunction - physiopathology | Respiratory Function Tests - methods | Treatment Outcome | Asthma - diagnostic imaging | Asthma - drug therapy | Vocal Cords - diagnostic imaging | Vocal Cord Dysfunction - diagnosis | Asthma - complications | Aged | Injections, Intramuscular - methods | Care and treatment | Paralysis | Analysis | Asthma
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10. Full Text Comprehensive Outcome Researches of Intralesional Steroid Injection on Benign Vocal Fold Lesions
by Wang, Chi-Te and Lai, Mei-Shu and Hsiao, Tzu-Yu
Journal of Voice, ISSN 0892-1997, 2015, Volume 29, Issue 5, pp. 578 - 587
Summary Objective This study investigated multidimensional treatment outcomes, including prognostic factors and side effects of vocal fold steroid injection... 
Otolaryngology | Atrophy | Occupation | Laryngopharyngeal reflux | Dexamethasone | Cyst | Hematoma | Varicosity | Ectasias | Triamcinolone | Nodules | Polyp | Vocal demand | SURGERY | VOICE THERAPY | ALTERNATIVE TREATMENT | REFLUX | AUDIOLOGY & SPEECH-LANGUAGE PATHOLOGY | VALIDATION | DISORDERS | RELIABILITY | HYGIENE EDUCATION | OTORHINOLARYNGOLOGY | VALIDITY | Cysts - drug therapy | Glucocorticoids - administration & dosage | Polyps - diagnosis | Vocal Cords - physiopathology | Prospective Studies | Humans | Middle Aged | Speech Production Measurement | Dexamethasone - adverse effects | Male | Acoustics | Laryngeal Diseases - physiopathology | Recovery of Function | Young Adult | Dexamethasone - analogs & derivatives | Time Factors | Injections, Intralesional | Voice Disorders - diagnosis | Adult | Female | Dilatation, Pathologic | Laryngeal Diseases - drug therapy | Glucocorticoids - adverse effects | Triamcinolone Acetonide - administration & dosage | Voice Disorders - physiopathology | Cysts - physiopathology | Disability Evaluation | Vocal Cords - drug effects | Vocal Cords - pathology | Dexamethasone - administration & dosage | Laryngeal Diseases - diagnosis | Voice Quality - drug effects | Treatment Outcome | Triamcinolone Acetonide - adverse effects | Laryngoscopy | Voice Disorders - drug therapy | Polyps - physiopathology | Adolescent | Polyps - drug therapy | Aged | Cysts - diagnosis | Medical colleges
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11. Full Text Dexamethasone Controlled Release on TGF-β1 Treated Vocal Fold Fibroblasts
by Kosinski, Aaron M and Pothen, Jewel M and Panitch, Alyssa and Sivasankar, M. Preeti
Annals of Otology, Rhinology & Laryngology, ISSN 0003-4894, 7/2015, Volume 124, Issue 7, pp. 572 - 578
Objective: Corticosteroids may be beneficial in treating vocal fold scarring. Current drug delivery methods do not permit controlled corticosteroid release.... 
PLGA microparticles | Drug delivery | Dexamethasone | Vocal fold scar | Glucocorticoids - administration & dosage | Vocal Cord Dysfunction - drug therapy | Humans | Transforming Growth Factor beta1 - metabolism | Drug Carriers | Cicatrix - metabolism | Polymerase Chain Reaction | Transforming Growth Factor beta1 - drug effects | Collagen - biosynthesis | Collagen - genetics | Vocal Cord Dysfunction - metabolism | Cytokines - genetics | Vocal Cords - metabolism | Fibroblasts - metabolism | Vocal Cords - drug effects | Vocal Cords - pathology | Dexamethasone - administration & dosage | Enzyme-Linked Immunosorbent Assay | Lactic Acid | Polyglycolic Acid | Vocal Cord Dysfunction - pathology | Cells, Cultured | Gene Expression Regulation | Cicatrix - drug therapy | Fibroblasts - drug effects | Biocompatible Materials | Cicatrix - pathology | Delayed-Action Preparations | Cytokines - biosynthesis
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12. Full Text Drug delivery system of basic fibroblast growth factor using gelatin hydrogel for restoration of acute vocal fold scar
by Kobayashi, Toshiki and Mizuta, Masanobu and Hiwatashi, Nao and Kishimoto, Yo and Nakamura, Tatsuo and Kanemaru, Shin-ichi and Hirano, Shigeru
Auris Nasus Larynx, ISSN 0385-8146, 2016, Volume 44, Issue 1, pp. 86 - 92
Abstract Objective There continue to be therapeutic challenges in the management of vocal fold scarring. We previously showed that basic fibroblast growth... 
Otolaryngology | Basic fibroblast growth factor | Hydrogel | Vocal fold scar | Drug delivery system | Vocal Cords - drug effects | Vocal Cords - pathology | Vibration | Hydrogels | Fibroblast Growth Factor 2 - pharmacology | Fibroblast Growth Factor 2 - administration & dosage | Drug Delivery Systems | Cicatrix - drug therapy | Regeneration - drug effects | Animals | Gelatin | Hyaluronic Acid - metabolism | Dogs | Mucous Membrane - drug effects | Vocal Cords - metabolism | Drugs | Medical colleges | Usage | Drug delivery systems | Biological products | Tissue engineering | Fibroblast growth factors | Health aspects | Vehicles | Analysis
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13. Full Text Efficacy and Safety of Adjunctive Steroid Injection After Microsurgical Removal of Benign Vocal Fold Lesions
by Cho, Jung-Hae and Kim, Sang-Yeon and Joo, Young-Hoon and Park, Young-Hak and Hwang, Woo-Seob and Sun, Dong-Il
Journal of Voice, ISSN 0892-1997, 2017, Volume 31, Issue 5, pp. 615 - 620
Summary Objective This study aims to investigate the clinical efficacy and safety of immediate intralesional steroid injection in patients undergoing laryngeal... 
Otolaryngology | Steroid | Dysphonia | Injection | Laryngeal microsurgery | Benign vocal fold lesion | OTORHINOLARYNGOLOGY | CORTICOSTEROID INJECTION | LARYNX | MICROFLAP | Multivariate Analysis | Recurrence | Steroids - administration & dosage | Vocal Cords - physiopathology | Humans | Middle Aged | Male | Laryngeal Diseases - pathology | Laryngeal Diseases - physiopathology | Microsurgery - adverse effects | Recovery of Function | Anti-Inflammatory Agents - adverse effects | Time Factors | Injections, Intralesional | Seoul | Adult | Anti-Inflammatory Agents - administration & dosage | Female | Vocal Cords - surgery | Retrospective Studies | Odds Ratio | Republic of Korea | Triamcinolone Acetonide - administration & dosage | Voice Disorders - physiopathology | Steroids - adverse effects | Vocal Cords - drug effects | Vocal Cords - pathology | Voice Disorders - therapy | Laryngeal Diseases - therapy | Stroboscopy | Risk Factors | Voice Quality - drug effects | Voice Disorders - pathology | Logistic Models | Treatment Outcome | Chi-Square Distribution | Triamcinolone Acetonide - adverse effects | Laryngoscopy | Laryngectomy - methods | Video Recording | Laryngectomy - adverse effects | Microsurgery - methods
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14. Full Text Protective Effect of Astaxanthin on Vocal Fold Injury and Inflammation Due to Vocal Loading: A Clinical Trial
by Kaneko, Mami and Kishimoto, Yo and Suzuki, Ryo and Kawai, Yoshitaka and Tateya, Ichiro and Hirano, Shigeru
Journal of Voice, ISSN 0892-1997, 2016, Volume 31, Issue 3, pp. 352 - 358
Summary Objectives Professional voice users, such as singers and teachers, are at greater risk of developing vocal fold injury from excessive use of voice;... 
Otolaryngology | Clinical trial | Reactive oxygen species | Vocal fold | Vocal loading | Astaxanthin | OXIDATIVE STRESS | FATIGUE | OTORHINOLARYNGOLOGY | ROS | CARDAX(TM) | MODEL | CARDIOPROTECTION | Vocal Cords - physiopathology | Humans | Male | Acoustics | Young Adult | Anti-Inflammatory Agents - adverse effects | Time Factors | Anti-Inflammatory Agents - therapeutic use | Adult | Vocal Cords - metabolism | Voice Disorders - physiopathology | Cytoprotection | Judgment | Disability Evaluation | Vocal Cords - drug effects | Voice Disorders - etiology | Xanthophylls - adverse effects | Stroboscopy | Voice Disorders - prevention & control | Voice Quality - drug effects | Phonation - drug effects | Treatment Outcome | Xanthophylls - therapeutic use | Antioxidants - therapeutic use | Self Concept | Voice Disorders - metabolism | Antioxidants - adverse effects | Oxidative Stress - drug effects | Auditory Perception | Antioxidants | Clinical trials | Usage | Inflammation
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15. Full Text Prevention of vocal fold scarring by local application of basic fibroblast growth factor in a rat vocal fold injury model
by Suzuki, Ryo and Kawai, Yoshitaka and Tsuji, Takuya and Hiwatashi, Nao and Kishimoto, Yo and Tateya, Ichiro and Nakamura, Tatsuo and Hirano, Shigeru
The Laryngoscope, ISSN 0023-852X, 02/2017, Volume 127, Issue 2, pp. E67 - E74
Objectives/Hypothesis: Vocal fold scarring, which causes severe hoarseness, is intractable. The optimal treatment for vocal fold scarring has not been... 
wound healing | Basic fibroblast growth factor | vocal fold scarring | extracellular matrix | MEDICINE, RESEARCH & EXPERIMENTAL | HISTOLOGIC CHARACTERIZATION | CANINE MODEL | MITOMYCIN-C | RECONSTRUCTION | REGENERATION | RABBIT MODEL | LARYNX | BOVINE ACELLULAR SCAFFOLD | MICROFLAP | INJECTION | OTORHINOLARYNGOLOGY | Vocal Cords - drug effects | Vocal Cords - pathology | Prospective Studies | Cicatrix - prevention & control | Vocal Cords - injuries | Rats | Male | Fibroblast Growth Factor 2 - administration & dosage | Rats, Sprague-Dawley | Animals | Cicatrix - pathology | Administration, Topical | Real-Time Polymerase Chain Reaction | Disease Models, Animal | Animal experimentation | Fibroblast growth factors | Hyaluronic acid | Collagen
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