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Nature, ISSN 0028-0836, 08/2012, Volume 488, Issue 7413, pp. 647 - 651
Autism spectrum disorders (ASDs) are highly prevalent neurodevelopmental disorders(1), but the underlying pathogenesis remains poorly understood. Recent... 
SURVIVAL | MTORC1 | TUBEROUS SCLEROSIS COMPLEX | MULTIDISCIPLINARY SCIENCES | MOUSE MODEL | ULTRASONIC VOCALIZATIONS | DISORDERS | BRAIN | CHILDREN | Autistic Disorder - pathology | Autistic Disorder - physiopathology | TOR Serine-Threonine Kinases - metabolism | Tuberous Sclerosis - complications | Cell Count | Cerebellum - drug effects | TOR Serine-Threonine Kinases - antagonists & inhibitors | Synapses - metabolism | Tumor Suppressor Proteins - deficiency | Tumor Suppressor Proteins - genetics | Behavior, Animal - drug effects | Vocalization, Animal - drug effects | Purkinje Cells - drug effects | Autistic Disorder - genetics | Grooming - physiology | Tumor Suppressor Proteins - metabolism | Purkinje Cells - metabolism | Maze Learning - physiology | Mice, Inbred C57BL | Grooming - drug effects | Vocalization, Animal - physiology | Cerebellum - physiopathology | Maze Learning - drug effects | Mutation - genetics | Sirolimus - pharmacology | Cerebellum - pathology | Tuberous Sclerosis - genetics | Cell Shape - drug effects | Rotarod Performance Test | Animals | Heterozygote | Mice | Mice, Inbred BALB C | Autistic Disorder - complications | Autism | Complications and side effects | Purkinje cells | Tuberous sclerosis | Physiological aspects | Research | Risk factors | Studies | Proteins | Pathogenesis | Social interaction | Rodents | Ataxia | Behavior | Animal cognition
Journal Article
Nature Neuroscience, ISSN 1097-6256, 02/2013, Volume 16, Issue 2, pp. 183 - 192
A major unresolved issue in treating pain is the paradoxical hyperalgesia produced by the gold-standard analgesic morphine and other opiates. We found that... 
LAMINA-I NEURONS | NEUROTROPHIC FACTOR | P2X RECEPTORS | DOWN-REGULATION | OPIOID-RECEPTOR GENE | SPINAL-CORD-INJURY | UNDERLYING NEUROPATHIC PAIN | ALTERED CHLORIDE HOMEOSTASIS | NERVE INJURY | NEUROSCIENCES | INDUCED ABNORMAL PAIN | Brain-Derived Neurotrophic Factor - genetics | Biophysical Phenomena - drug effects | Motor Activity - drug effects | Male | Ribosome Inactivating Proteins, Type 1 - pharmacology | Touch | CD11b Antigen - genetics | Microglia - physiology | Time Factors | Chlorides - metabolism | Pain Threshold - drug effects | Biophysical Phenomena - genetics | Vocalization, Animal - drug effects | Brain-Derived Neurotrophic Factor - metabolism | Homeostasis - drug effects | Protein Synthesis Inhibitors - pharmacology | Spinal Cord - cytology | Neurons - drug effects | Membrane Potentials - drug effects | Hot Temperature - adverse effects | Microglia - drug effects | Mice, Inbred C57BL | Rats | Mice, Transgenic | Signal Transduction - genetics | Down-Regulation - drug effects | Rats, Sprague-Dawley | Symporters - metabolism | Gene Expression Regulation - drug effects | Narcotics - administration & dosage | Patch-Clamp Techniques | Rotarod Performance Test | Animals | Hyperalgesia - drug therapy | Signal Transduction - drug effects | Naloxone - pharmacology | Narcotic Antagonists - pharmacology | Mice | CD11b Antigen - metabolism | Receptors, Purinergic P2X4 - metabolism | Morphine - administration & dosage | Receptors, Purinergic P2X4 - genetics | Ion Channel Gating - drug effects
Journal Article
Neurobiology of Disease, ISSN 0969-9961, 2015, Volume 82, pp. 185 - 199
Journal Article
Nature Neuroscience, ISSN 1097-6256, 03/2015, Volume 18, Issue 3, pp. 435 - 446
Journal Article
Journal Article
Journal Article
Nature Neuroscience, ISSN 1097-6256, 05/2008, Volume 11, Issue 5, pp. 579 - 586
Journal Article
Science Translational Medicine, ISSN 1946-6234, 04/2012, Volume 4, Issue 131, pp. 131ra51 - 131ra51
Journal Article
Psychopharmacology, ISSN 0033-3158, 2/2012, Volume 219, Issue 4, pp. 1141 - 1152
Subtypes of 50-kHz ultrasonic vocalizations (USVs) in rats are thought to reflect positive affect and occur with cocaine or amphetamine delivery. In contexts... 
Self-administration | Neurosciences | Relapse | Extinction | Craving | Rats | Yoked | Biomedicine | Addiction | Cocaine seeking | Reward | Pharmacology/Toxicology | Psychiatry | Deprivation effect | DRUG | ADULT RATS | PSYCHIATRY |