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Journal Article
by Niu, X and Zhang, T and Liao, L and Zhou, L and Lindner, D.J and Zhou, M and Rini, B and Yan, Q and Yang, H
Oncogene, ISSN 0950-9232, 02/2012, Volume 31, Issue 6, pp. 776 - 786
In clear-cell renal cell carcinoma (ccRCC), inactivation of the tumor suppressor von Hippel-Lindau (VHL) occurs in the majority of the tumors and is causal for... 
hypoxia-inducible factor | JARID1C/KDM5C/SMCX | von Hippel-Lindau | gene expression | trimethyl H3K4 | METHYLATION | ACTIVATION | PROLYL HYDROXYLATION | STABILIZATION | BIOCHEMISTRY & MOLECULAR BIOLOGY | HYPOXIA-INDUCIBLE-FACTOR | CANCER | RENAL-CELL CARCINOMA | CELL BIOLOGY | INACTIVATION | INHIBITION | ONCOLOGY | GENETICS & HEREDITY | HIF-ALPHA | Insulin-Like Growth Factor Binding Protein 3 - genetics | Kidney Neoplasms - genetics | Oxidoreductases, N-Demethylating - genetics | Cell Proliferation | Humans | Collagen Type VI - metabolism | Gene Expression Regulation, Neoplastic | Carcinoma, Renal Cell - genetics | Transplantation, Heterologous | Kidney Neoplasms - metabolism | Collagen Type VI - genetics | Basic Helix-Loop-Helix Transcription Factors - metabolism | Insulin-Like Growth Factor Binding Protein 3 - metabolism | RNA Interference | Hypoxia-Inducible Factor 1, alpha Subunit - metabolism | HEK293 Cells | Lysine - metabolism | Von Hippel-Lindau Tumor Suppressor Protein - genetics | Oxidoreductases, N-Demethylating - metabolism | Von Hippel-Lindau Tumor Suppressor Protein - metabolism | Basic Helix-Loop-Helix Transcription Factors - genetics | Carcinoma, Renal Cell - pathology | Hypoxia-Inducible Factor 1, alpha Subunit - genetics | Tumor Burden | Reverse Transcriptase Polymerase Chain Reaction | Blotting, Western | Carcinoma, Renal Cell - metabolism | Animals | Histone Demethylases | Mice, Nude | Cell Line, Tumor | Kidney Neoplasms - pathology | Mice | Histones - metabolism | Mutation | Methylation | Histones | Physiological aspects | Tumor suppressor genes | Genetic aspects | Research | Carcinoma, Renal cell | Gene expression | Proteins | Kidney diseases | Cellular biology | Cancer | Hypoxia-inducible factors | Enzymes | RNA | Promoters | renal cell carcinoma | Lysine | Xenografts | Insulin-like growth factor-binding protein 3 | genomics | Tumorigenesis | VHL protein | Differentiation | Neoplasia | Histone H3 | Oncogenes | Index Medicus | KDM5C | JARID1C | hypoxia inducible factor | SMCX
Journal Article
Journal Article
Cancer Research, ISSN 0008-5472, 03/2006, Volume 66, Issue 5, pp. 2725 - 2731
A critical event in the pathogenesis of invasive and metastatic cancer is E-cadherin loss of function. Renal clear cell carcinoma (RCC) is characterized by... 
BREAST-CANCER | INVASION | PROTEIN | FACTOR-1 | THERAPY | GENE | ONCOLOGY | TRANSCRIPTION FACTOR SNAIL | EPITHELIAL-MESENCHYMAL TRANSITIONS | HIF-ALPHA | EXPRESSION | Immunohistochemistry | RNA, Small Interfering - genetics | Kidney Neoplasms - genetics | Humans | Gene Expression Regulation, Neoplastic | Carcinoma, Renal Cell - genetics | Kidney Neoplasms - metabolism | Zinc Finger E-box Binding Homeobox 2 | Cadherins - biosynthesis | Hypoxia-Inducible Factor 1 - genetics | Repressor Proteins - physiology | RNA, Messenger - biosynthesis | Basic Helix-Loop-Helix Transcription Factors - biosynthesis | Transcription, Genetic | Von Hippel-Lindau Tumor Suppressor Protein - genetics | Cadherins - genetics | Hypoxia-Inducible Factor 1 - biosynthesis | Basic Helix-Loop-Helix Transcription Factors - physiology | Transcription Factors - physiology | Basic Helix-Loop-Helix Transcription Factors - genetics | Homeodomain Proteins - biosynthesis | Carcinoma, Renal Cell - pathology | Down-Regulation | Hypoxia-Inducible Factor 1 - physiology | RNA, Messenger - genetics | Von Hippel-Lindau Tumor Suppressor Protein - biosynthesis | Repressor Proteins - genetics | Von Hippel-Lindau Tumor Suppressor Protein - physiology | Epithelial Cells - pathology | Transcription Factors - biosynthesis | Transcription Factors - genetics | Homeodomain Proteins - genetics | Carcinoma, Renal Cell - metabolism | Repressor Proteins - biosynthesis | Biopsy | Cell Adhesion - physiology | Kidney Neoplasms - pathology | Homeodomain Proteins - physiology | Mesoderm - pathology | Zinc Finger E-box-Binding Homeobox 1 | Index Medicus
Journal Article
PLoS Genetics, ISSN 1553-7390, 10/2011, Volume 7, Issue 10, pp. e1002312 - e1002312
Journal Article
Nature Genetics, ISSN 1061-4036, 2014, Volume 46, Issue 3, pp. 225 - 233
Journal Article
Blood, ISSN 0006-4971, 2009, Volume 113, Issue 25, pp. 6449 - 6460
Journal Article
Journal Article
Journal Article
Oncogene, ISSN 0950-9232, 02/2015, Volume 34, Issue 6, pp. 771 - 9
Journal Article