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Antimicrobial Agents and Chemotherapy, ISSN 0066-4804, 12/2014, Volume 58, Issue 12, pp. 7121 - 7127
Journal Article
Journal Article
Journal Article
Journal of Biological Chemistry, ISSN 0021-9258, 10/2010, Volume 285, Issue 41, pp. 31783 - 31795
Journal Article
Journal Article
Chemical research in toxicology, ISSN 0893-228X, 09/2012, Volume 25, Issue 9, pp. 1938 - 1947
Journal Article
PloS one, ISSN 1932-6203, 2016, Volume 11, Issue 12, p. e0167961
Voriconazole (VRC) incorporated in composited polyvinyl alcohol (PVA)/hydroxypropyl-beta cyclodextrin (HP beta CD) blended nanofibers were produced via... 
OCULAR INSERTS | VITRO | ANTIFUNGAL DRUGS | CYCLOSPORINE-A | STABILITY | MULTIDISCIPLINARY SCIENCES | DRUG-RELEASE | FORMULATION | IN-VIVO EVALUATION | SUSTAINED-RELEASE | SOLUBILITY | 2-Hydroxypropyl-beta-cyclodextrin | Nanofibers - chemistry | Polyvinyl Alcohol - chemistry | Rabbits | Microscopy, Electron, Scanning | Magnetic Resonance Spectroscopy | Area Under Curve | Solubility | Male | Antifungal Agents - chemistry | Spectroscopy, Fourier Transform Infrared | Drug Carriers | Voriconazole - pharmacokinetics | Animals | beta-Cyclodextrins - chemistry | X-Ray Diffraction | Antifungal Agents - pharmacokinetics | Drug Design | Electrochemistry | Ophthalmic Solutions | Calorimetry, Differential Scanning | Voriconazole - chemistry | Tears | Infrared spectroscopy | Fourier transformation | Cornea | Drug delivery systems | Nuclear magnetic resonance--NMR | Electrospinning | Alcohol | Drug delivery | Cyclodextrins | Fungal infections | Infrared analysis | Polymer melts | Voriconazole | Biocompatibility | Polyvinyl alcohol | Bearing strength | Irritation | Scanning electron microscopy | Differential scanning calorimetry | Pharmacodynamics | Thermogravimetric analysis | Pharmacology | Bioavailability | Electron microscopy | Differential thermogravimetric analysis | Cyclodextrin | Pharmacy | Calorimetry | Thermal analysis | Nanofibers | Nuclear magnetic resonance | NMR
Journal Article
Journal Article
ANTIMICROBIAL AGENTS AND CHEMOTHERAPY, ISSN 0066-4804, 03/2018, Volume 62, Issue 3
Fungal infections frequently affect immunodeficient individuals and are estimated to kill 1.35 million people per annum. Azole antifungals target the... 
lanosterol 14 alpha-demethylase | CYTOCHROME-P450 | SUBSTITUTION | ASPERGILLUS-FUMIGATUS | REDUCED SUSCEPTIBILITY | voriconazole | CROSS-RESISTANCE | MICROBIOLOGY | itraconazole | CYP51A | antifungal resistance | CYP51 | fungal infections | X-ray crystallography | fluconazole | AMINO-ACID | drug resistance mechanisms | AZOLE RESISTANCE | PHARMACOLOGY & PHARMACY | BINDING | Fungal Proteins - chemistry | Fluconazole - pharmacology | Fluconazole - chemistry | Saccharomyces cerevisiae - genetics | Sterol 14-Demethylase - genetics | Aspergillus fumigatus - enzymology | Substrate Specificity | Crystallography, X-Ray | Saccharomyces cerevisiae - drug effects | Antifungal Agents - chemistry | Histidine - metabolism | Recombinant Fusion Proteins - metabolism | Itraconazole - pharmacology | Candida albicans - genetics | Fluconazole - metabolism | Microbial Sensitivity Tests | Antifungal Agents - metabolism | Cloning, Molecular | Protein Interaction Domains and Motifs | Antifungal Agents - pharmacology | Itraconazole - metabolism | Recombinant Proteins - metabolism | Protein Conformation, alpha-Helical | Catalytic Domain | Gene Expression | Genetic Vectors - chemistry | Oligopeptides - genetics | Genetic Vectors - metabolism | Histidine - genetics | Models, Molecular | Recombinant Proteins - chemistry | Recombinant Proteins - genetics | Drug Resistance, Fungal - genetics | Fungal Proteins - genetics | Itraconazole - chemistry | Oligopeptides - metabolism | Recombinant Fusion Proteins - chemistry | Aspergillus fumigatus - genetics | Protein Binding | Recombinant Fusion Proteins - genetics | Saccharomyces cerevisiae - enzymology | Sterol 14-Demethylase - metabolism | Kinetics | Mutation | Sterol 14-Demethylase - chemistry | Candida albicans - enzymology | Fungal Proteins - metabolism
Journal Article
ACS Nano, ISSN 1936-0851, 01/2011, Volume 5, Issue 1, pp. 199 - 208
Journal Article
FEMS Yeast Research, ISSN 1567-1356, 05/2017, Volume 17, Issue 3
The increasing prevalence of azole resistance in Candida albicans poses a growing problem for clinical treatment. Amino acid substitution of the 14... 
Candida albicans | Azole resistance | The amino acid substitution T123I | Homology modeling | Heterologous expression | azole resistance | SUSCEPTIBILITY | MICROBIOLOGY | heterologous expression | MECHANISMS | DRUG-RESISTANCE | SACCHAROMYCES-CEREVISIAE | homology modeling | CLONING | BIOTECHNOLOGY & APPLIED MICROBIOLOGY | the amino acid substitution T123I | MUTATIONS | MYCOLOGY | Fungal Proteins - chemistry | Fluconazole - pharmacology | Phosphorylation | Threonine - chemistry | Fluconazole - chemistry | Voriconazole - pharmacology | Saccharomyces cerevisiae - genetics | Open Reading Frames | Cytochrome P-450 Enzyme System - metabolism | Saccharomyces cerevisiae - drug effects | Antifungal Agents - chemistry | Threonine - metabolism | Itraconazole - pharmacology | Candida albicans - genetics | Microbial Sensitivity Tests | Candida albicans - drug effects | Isoleucine - chemistry | Protein Interaction Domains and Motifs | Binding Sites | Antifungal Agents - pharmacology | Gene Expression Regulation, Fungal | Protein Conformation, alpha-Helical | Models, Molecular | Drug Resistance, Fungal - genetics | Fungal Proteins - genetics | Itraconazole - chemistry | Isoleucine - metabolism | Cytochrome P-450 Enzyme System - chemistry | Cytochrome P-450 Enzyme System - genetics | Protein Binding | Saccharomyces cerevisiae - enzymology | Voriconazole - chemistry | Amino Acid Substitution | Candida albicans - enzymology | Fungal Proteins - metabolism
Journal Article