X
Search Filters
Format Format
Subjects Subjects
Subjects Subjects
X
Sort by Item Count (A-Z)
Filter by Count
index medicus (100) 100
wdr5 (96) 96
humans (67) 67
methylation (59) 59
biochemistry & molecular biology (54) 54
histones - metabolism (50) 50
histone-lysine n-methyltransferase - metabolism (45) 45
animals (44) 44
chromatin (43) 43
cell biology (42) 42
histone h3 (33) 33
protein binding (33) 33
structural basis (33) 33
histone-lysine n-methyltransferase - genetics (31) 31
gene-expression (29) 29
mice (26) 26
molecular recognition (26) 26
proteins (26) 26
complex (24) 24
protein wdr5 (23) 23
histones (22) 22
gene expression (21) 21
myeloid-lymphoid leukemia protein - metabolism (21) 21
research (20) 20
recognition (19) 19
cancer (18) 18
histone-lysine n-methyltransferase - chemistry (18) 18
leukemia (18) 18
epigenetics (17) 17
histones - chemistry (17) 17
transcription factors - metabolism (17) 17
article (16) 16
cell line, tumor (16) 16
mll (16) 16
myeloid-lymphoid leukemia protein - genetics (16) 16
transcription (16) 16
analysis (15) 15
epigenesis, genetic (15) 15
binding (14) 14
nuclear proteins - metabolism (14) 14
chromatin - metabolism (13) 13
dna methylation (13) 13
dna-binding proteins - metabolism (13) 13
genetic aspects (13) 13
lysine - metabolism (13) 13
myeloid-lymphoid leukemia protein - chemistry (13) 13
binding sites (12) 12
gene expression regulation (12) 12
histone-lysine n-methyltransferase - antagonists & inhibitors (12) 12
histones - genetics (12) 12
lysine (12) 12
mixed-lineage leukemia (12) 12
mll1 (12) 12
models, molecular (12) 12
proteins - metabolism (12) 12
stem cells (12) 12
biophysics (11) 11
h3k4 methylation (11) 11
histone methylation (11) 11
methyltransferases (11) 11
nuclear proteins - genetics (11) 11
physiological aspects (11) 11
promoter regions, genetic (11) 11
transcription factors - genetics (11) 11
biology (10) 10
cells (10) 10
h3k4 methyltransferase activity (10) 10
h3k4me3 (10) 10
molecular biology (10) 10
molecular regulation (10) 10
protein (10) 10
saccharomyces-cerevisiae (10) 10
self-renewal (10) 10
cell proliferation (9) 9
crystal structure (9) 9
crystallography, x-ray (9) 9
differentiation (9) 9
hek293 cells (9) 9
hela cells (9) 9
peptides (9) 9
rbbp5 (9) 9
rna interference (9) 9
ash2l (8) 8
developmental biology (8) 8
dna-binding proteins - genetics (8) 8
expression (8) 8
gene regulation (8) 8
genes (8) 8
genetics & heredity (8) 8
methyltransferase (8) 8
methyltransferase activity (8) 8
models, biological (8) 8
protein structure, tertiary (8) 8
structure (8) 8
transcription, genetic (8) 8
amino acid sequence (7) 7
chemistry, medicinal (7) 7
chromatin immunoprecipitation (7) 7
embryonic stem-cells (7) 7
enzymes (7) 7
more...
Language Language
Publication Date Publication Date
Click on a bar to filter by decade
Slide to change publication date range


Cancer Epidemiology Biomarkers and Prevention, ISSN 1055-9965, 09/2018, Volume 27, Issue 9, pp. 1091 - 1100
Background: Hepatocellular carcinoma (HCC) is the second leading cause of cancer-related death worldwide. There is an urgent demand for prognostic biomarkers... 
TARGET | PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH | METASTASIS | EXOCYTOSIS | ONCOLOGY | GROWTH | WDR5 | GENOMIC CHARACTERIZATION | CANCER | PROGRESSION
Journal Article
Biochemical Journal, ISSN 0264-6021, 01/2013, Volume 449, Issue 1, pp. 151 - 159
Journal Article
Autophagy, ISSN 1554-8627, 06/2015, Volume 11, Issue 6, pp. 881 - 890
WDR45/WIPI4, encoding a WD40 repeat-containing PtdIns(3)P binding protein, is essential for the basal autophagy pathway. Mutations in WDR45 cause the... 
fEPSP, field excitatory postsynaptic potential | SQSTM1, sequestosome-1 | epg, ectopic P granule | neurodegeneration | SENDA, static encephalopathy of childhood with neurodegeneration in adulthood | BPAN, β-propeller protein-associated neurodegeneration | axon swelling | H&E, hematoxylin and eosin | AMC, aminomethylcoumarin | LC3, microtubule-associated protein 1 light chain 3 | NBIA, neurodegeneration with brain iron accumulation | Atg, autophagy-related | rpm, rotations per min | autophagy | ACTB, β-actin | CALB, calbindin | WT, wild type | LTP, long-term potentiation | GFAP, glial fibrillary acid protein | CNS, central nervous system | Ei24, etoposide-induced gene 24 | MBP, myelin basic protein | learning and memory | KO, knockout | RBFOX3, RNA binding protein, fox-1 homolog (C. elegans) 3 | Wdr45/Wipi4 | WDR5/WIPI4, WD repeat domain 45 | DCN, deep cerebellar nuclei | Learning and memory | Axon swelling | Neurodegeneration | Autophagy | BRAIN IRON ACCUMULATION | DEGENERATION | CELL BIOLOGY | TRANSPORT | DISEASE | BASAL AUTOPHAGY | MICE | MUTATIONS | Carrier Proteins - genetics | Learning - physiology | Animals | Axons - metabolism | Mice, Transgenic | Autophagy - physiology | Autophagy - genetics | Neurodegenerative Diseases - metabolism | Mutation - genetics | Homeostasis - genetics | Memory - physiology | Index Medicus
Journal Article
Journal Article
FRONTIERS IN IMMUNOLOGY, ISSN 1664-3224, 07/2019, Volume 10, pp. 1661 - 1661
Myeloid-derived suppressor cells (MDSCs), which play an important role in tumor and inflammatory diseases, are divided into two subsets CD11b(+)Ly6C(hi)Ly6G(-)... 
MDSC | lncRNA | DENDRITIC CELLS | H3K4me3 | WDR5 | SUPPRESSOR-CELLS | IMMUNOLOGY | IL4il | MYELOID CELLS | Index Medicus
Journal Article
Journal Article
Molecular Cell, ISSN 1097-2765, 01/2014, Volume 53, Issue 2, pp. 247 - 261
Journal Article
Journal Article
Journal Article
Nucleic Acids Research, ISSN 0305-1048, 04/2018, Volume 46, Issue 7, pp. 3802 - 3812
Abstract The multi-protein complex WRAD, formed by WDR5, RbBP5, Ash2L and Dpy30, binds to the MLL SET domain to stabilize the catalytically active conformation... 
SET DOMAIN | LINEAGE LEUKEMIA PROTEIN-1 | LONG NONCODING RNAS | CHROMATIN | RECOGNITION | BIOCHEMISTRY & MOLECULAR BIOLOGY | H3K4 METHYLATION | GENE-EXPRESSION | WDR5 | HISTONE MODIFICATIONS | METHYLTRANSFERASE COMPLEXES | Index Medicus | Structural Biology
Journal Article
Journal of Cellular Physiology, ISSN 0021-9541, 05/2019, Volume 234, Issue 5, pp. 6244 - 6253
Expression of Runx2/p57 is a hallmark of the osteoblast‐lineage identity. Although several regulators that control the expression of Runx2/p57 during... 
epigenetic control of osteoblast gene transcription | osteoblast differentiation | Runx2 | LINEAGE COMMITMENT | PHYSIOLOGY | WD-40 REPEAT PROTEIN | PROMOTERS | WDR5 | DIFFERENTIATION | FAMILY | CELL BIOLOGY | Proteins | Enrichment | Cbfa-1 protein | Regulators | Chromatin | Mesenchyme | Transcription | Epigenetics | Biocompatibility | Gene expression | Osteoblasts
Journal Article