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1. Pillars Article: Isolation of a Novel Gene Mutated in Wiskott-Aldrich Syndrome. Cell. 1994. 78: 635–644
by Derry Jonathan M J and Ochs Hans D and Francke Uta
The Journal of Immunology, ISSN 0022-1767, 06/2018, Volume 200, Issue 11, pp. 3671 - 3680
Wiskott-Aldrich syndrome
Journal Article
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2. Full Text Outcomes following hematopoietic cell transplantation for WiskottAldrich syndrome
by Shin, C.R and Kim, M.-O and Li, D and Bleesing, J.J and Harris, R and Mehta, P and Jodele, S and Jordan, M.B and Marsh, R.A and Davies, S.M and Filipovich, A.H
Bone Marrow Transplantation, ISSN 0268-3369, 11/2012, Volume 47, Issue 11, pp. 1428 - 1435
long term outcomes | hematopoietic cell transplantation | Wiskott-Aldrich syndrome(s)
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3. Full Text A male infant with eczema and persistent thrombocytopenia, without micro-platelets: an atypical Wiskott-Aldrich syndrome?
by De Castro, Maria Eduarda Pontes Cunha and Poli, Juliana Leticia and Jr, Persio Roxo and De Albuquerque, Paula Danielle Santa Maria
World Allergy Organization Journal, ISSN 1939-4551, 04/2015, Volume 8, Issue 135
Wiskott-Aldrich syndrome
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4. Full Text Gene therapy returns to centre stage
by Naldini, Luigi
Nature, ISSN 0028-0836, 10/2015, Volume 526, Issue 7573, pp. 351 - 360
Recent clinical trials of gene therapy have shown remarkable therapeutic benefits and an excellent safety record. They provide evidence for the long-sought... 
SEVERE COMBINED IMMUNODEFICIENCY | CHRONIC GRANULOMATOUS-DISEASE | MULTIDISCIPLINARY SCIENCES | CHIMERIC-ANTIGEN-RECEPTOR | LONG-TERM SAFETY | WISKOTT-ALDRICH SYNDROME | X-LINKED ADRENOLEUKODYSTROPHY | STEM-CELL TRANSPLANTATION | PHASE I/II TRIAL | LEBERS CONGENITAL AMAUROSIS | ZINC-FINGER NUCLEASES | Gene Targeting | Humans | Liver - metabolism | Clinical Trials as Topic | Hematopoietic Stem Cells - metabolism | Genetic Therapy - trends | Organ Specificity | T-Lymphocytes - transplantation | Neoplasms - therapy | Neoplasms - immunology | Immunotherapy | T-Lymphocytes - immunology | Neoplasms - pathology | Genetic Therapy - methods | Gene therapy | Forecasts and trends | Methods | Immunology | Biological products | Disease | Cytokines | Stem cells | Bone marrow | Genetic engineering | Vectors (Biology) | Morbidity | Immune system
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5. Full Text Cracking the platelet WIP
by Poole, Alastair W
Blood, ISSN 0006-4971, 11/2009, Volume 114, Issue 21, pp. 4611 - 4612
HEMATOLOGY | WISKOTT-ALDRICH-SYNDROME
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6. Full Text Lentiviral Hematopoietic Stem Cell Gene Therapy in Patients with Wiskott-Aldrich Syndrome
by Alessandro Aiuti and Luca Biasco and Samantha Scaramuzza and Francesca Ferrua and Maria Pia Cicalese and Cristina Baricordi and Francesca Dionisio and Andrea Calabria and Stefania Giannelli and Maria Carmina Castiello and Marita Bosticardo and Costanza Evangelio and Andrea Assanelli and Miriam Casiraghi and Sara Di Nunzio and Luciano Callegaro and Claudia Benati and Paolo Rizzardi and Danilo Pellin and Clelia Di Serio and Manfred Schmidt and Christof Von Kalle and Jason Gardner and Nalini Mehta and Victor Neduva and David J. Dow and Anne Galy and Roberto Miniero and Andrea Finocchi and Ayse Metin and Pinaki P. Banerjee and Jordan S. Orange and Stefania Galimberti and Maria Grazia Valsecchi and Alessandra Biffi and Eugenio Montini and Anna Villa and Fabio Ciceri and Maria Grazia Roncarolo and Luigi Naldini
Science, ISSN 0036-8075, 8/2013, Volume 341, Issue 6148, pp. 865 - 865
Wiskott-Aldrich syndrome (WAS) is an inherited immunodeficiency caused by mutations in the gene encoding WASP, a protein regulating the cytoskeleton.... 
RESEARCH ARTICLE SUMMARY | EFFICACY | RETROVIRAL INTEGRATION SITES | MULTIDISCIPLINARY SCIENCES | MOUSE MODEL | SYNDROME PROTEIN | IMMUNODEFICIENCIES | EXPRESSION | T-CELLS | VECTOR | TRANSPLANTATION | WASP | Wiskott-Aldrich Syndrome - therapy | Wiskott-Aldrich Syndrome Protein - genetics | Transduction, Genetic | Humans | Hematopoietic Stem Cell Transplantation | Male | Hematopoietic Stem Cells - metabolism | Genetic Vectors | Virus Integration | Child | Lentivirus | Genetic Therapy - methods | Mathematical analysis | Genes | Stem cells | Disorders | Vectors (mathematics) | Gene therapy | Online | Patients
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7. Full Text Mutation in VPS35 associated with Parkinson's disease impairs WASH complex association and inhibits autophagy
by Zavodszky, Eszter and Seaman, Matthew N.J and Moreau, Kevin and Jimenez-Sanchez, Maria and Breusegem, Sophia Y and Harbour, Michael E and Rubinsztein, David C
Nature Communications, ISSN 2041-1723, 05/2014, Volume 5, p. 3828
Endosomal protein sorting controls the localization of many physiologically important proteins and is linked to several neurodegenerative diseases. VPS35 is a... 
ATG9 TRAFFICKING | RECRUITMENT | OVEREXPRESSION | POLYGLUTAMINE | PROTEIN | ACTIN | INTERACTS | MULTIDISCIPLINARY SCIENCES | RETROMER COMPLEX | ALPHA-SYNUCLEIN | IDENTIFICATION | Autophagy-Related Proteins | Wiskott-Aldrich Syndrome Protein Family - metabolism | Vesicular Transport Proteins - metabolism | Humans | Vesicular Transport Proteins - genetics | Parkinson Disease - genetics | Endosomes - metabolism | Protein Transport - genetics | Cell Line, Tumor | Golgi Apparatus - metabolism | Membrane Proteins - metabolism | Autophagy - genetics | HeLa Cells
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8. Full Text New insights into the regulation and cellular functions of the ARP2/3 complex
by Rotty, Jeremy D and Wu, Congying and Bear, James E
Nature Reviews Molecular Cell Biology, ISSN 1471-0072, 01/2013, Volume 14, Issue 1, pp. 7 - 12
The actin-related protein 2/3 (ARP2/3) complex nucleates branched actin filament networks, but requires nucleation promoting factors (NPFs) to stimulate this... 
MIGRATION | CYTOSKELETON | ACTIN POLYMERIZATION | CORTACTIN | LAMELLIPODIA | N-WASP | NETWORKS | NUCLEATION | ALDRICH-SYNDROME PROTEIN | BINDING | CELL BIOLOGY | Actin-Related Protein 2-3 Complex - metabolism | Wiskott-Aldrich Syndrome Protein Family - metabolism | Humans | Wiskott-Aldrich Syndrome Protein - metabolism | Cytoskeletal Proteins - metabolism | Protein Conformation | Microfilament Proteins - metabolism | Wiskott-Aldrich Syndrome Protein, Neuronal - metabolism | Cell Movement | Protein Transport | Motility | Actin | Physiological aspects | Research | Health aspects | Cells | Membrane proteins
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9. Full Text The 'ins' and 'outs' of podosomes and invadopodia: characteristics, formation and function
by Murphy, Danielle A and Courtneidge, Sara A
Nature Reviews Molecular Cell Biology, ISSN 1471-0072, 07/2011, Volume 12, Issue 7, pp. 413 - 426
Podosomes and invadopodia are actin-based dynamic protrusions of the plasma membrane of metazoan cells that represent sites of attachment to-and degradation... 
TYROSINE KINASE | 3-DIMENSIONAL MIGRATION | WISKOTT-ALDRICH-SYNDROME | TUMOR-CELL INVASION | EXTRACELLULAR-MATRIX DEGRADATION | FOCAL ADHESION KINASE | ALPHA(V)BETA INTEGRIN | MASTER REGULATOR | C-SRC | MICRORNA CONTROL | CELL BIOLOGY | Neoplasms - metabolism | Cell Surface Extensions - ultrastructure | Cell Surface Extensions - metabolism | Neoplasm Invasiveness | Humans | Actins - metabolism | Cortactin - metabolism | Cell Movement - physiology | Microscopy, Immunoelectron | Animals | Wiskott-Aldrich Syndrome Protein - metabolism | Neoplasms - pathology | Cell Surface Extensions - physiology | Physiological aspects | Phosphorylation | Research | Gene expression | Actin | Integrins
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10. Full Text Resistant widespread facial impetigo in a healthy infant with atopic dermatitis
by Nabavizadeh, Seyed Hesamedin and Fazel, Ali and Alyasin, Soheila and Bahadoram, Mohammad and Houshmand, Gholamreza
Journal of Clinical and Diagnostic Research, ISSN 2249-782X, 03/2018, Volume 12, Issue 3, pp. SD01 - SD03
Infant | Hypogammaglobulinemia | Wiskott-aldrich syndrome | Clindamycin | Immunodeficiency
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11. Full Text Steering cell migration: Lamellipodium dynamics and the regulation of directional persistence
by Krause, Matthias and Gautreau, Alexis
Nature Reviews Molecular Cell Biology, ISSN 1471-0072, 2014, Volume 15, Issue 9, pp. 577 - 590
Membrane protrusions at the leading edge of cells, known as lamellipodia, drive cell migration in many normal and pathological situations. Lamellipodial... 
BREAST-CANCER CELLS | ABL-MEDIATED PHOSPHORYLATION | MATURATION FACTOR-GAMMA | LEADING-EDGE | ACTIN-BASED MOTILITY | WAVE2 SIGNALING COMPLEX | ARP2/3 COMPLEX | ALDRICH-SYNDROME PROTEIN | CAPPING PROTEIN | VASODILATOR-STIMULATED PHOSPHOPROTEIN | CELL BIOLOGY | Actin-Related Protein 2-3 Complex - metabolism | Animals | Pseudopodia - metabolism | Wiskott-Aldrich Syndrome Protein Family - metabolism | Humans | Actins - metabolism | Pseudopodia - genetics | Actin-Related Protein 2-3 Complex - genetics | Wiskott-Aldrich Syndrome Protein Family - genetics | Cell Movement - physiology | Actins - genetics | Physiological aspects | Research | Muscle proteins | Structure | Lamellipodia | Cell migration
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12. Full Text WHAMM initiates autolysosome tubulation by promoting actin polymerization on autolysosomes
by Dai, Anbang and Yu, Li and Wang, Hong-Wei
Nature communications, ISSN 2041-1723, 08/2019, Volume 10, Issue 1, pp. 3699 - 14
WHAMM, a member of the Wiskott-Aldrich syndrome protein (WASP) family, is an actin nucleation promoting factor (NPF) that also associates with membranes and... 
Wiskott-Aldrich syndrome | Membranes | Starvation | Nucleation | Actin | Microtubules | Polymerization | Scaffolds | Polyimide resins
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13. Full Text A nucleator arms race: cellular control of actin assembly
by Campellone, Kenneth G and Welch, Matthew D
Nature Reviews Molecular Cell Biology, ISSN 1471-0072, 04/2010, Volume 11, Issue 4, pp. 237 - 251
For over a decade, the actin-related protein 2/3 (ARP2/3) complex, a handful of nucleation-promoting factors and formins were the only molecules known to... 
DOMAIN-CONTAINING PROTEIN | STRUCTURAL BASIS | WISKOTT-ALDRICH-SYNDROME | CLATHRIN-COATED PITS | X-RAY-SCATTERING | DIAPHANOUS-RELATED FORMIN | WASP-WIP COMPLEX | ARP2/3 COMPLEX | N-WASP | BINDING PROTEIN | CELL BIOLOGY | Actin-Related Protein 2-3 Complex - metabolism | Actin Cytoskeleton - metabolism | Animals | Humans | Actins - metabolism | Nuclear Proteins - physiology | Wiskott-Aldrich Syndrome Protein Family - physiology | Trans-Activators - physiology | Physiological aspects | Polymerization | Research | Muscle proteins | Actin | Adenosine triphosphate
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