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01/2009
Our aim was to investigate the effect of Withaferin-A on bone marrow micronucleus frequency and buccal mucosa detoxication agents during 7,... 
Oral cancer | Micronucleus | DMBA | Detoxication | Withaferin-A
Web Resource
01/2009
The aim of the present study was to investigate the protective effect of Withaferin-A on red blood cell integrity during 7,12-dimethylbenz[a]anthracene (DMBA)... 
osmotic fragility | Oral cancer | glycoconjugates | DMBA | Withaferin-A
Web Resource
Experimental Cell Research, ISSN 0014-4827, 10/2019, Volume 383, Issue 2, p. 111564
Inflammasomes are cytoplasmic protein complexes that regulate the secretion of pro-inflammatory cytokines including IL-1β and IL18, thereby playing a crucial... 
Withaferin A | AIM2 inflammasome | THP-1 macrophage polarization
Journal Article
Natural Product Research, ISSN 1478-6419, 2018, Volume 33, Issue 21, pp. 3157 - 3160
Journal Article
ANTICANCER RESEARCH, ISSN 0250-7005, 07/2019, Volume 39, Issue 7, pp. 3423 - 3427
Current clinical failure to cure primary glioblastoma multiforme in virtually all adult patients is due to genetic aberrations, molecular heterogeneity, and... 
APOPTOSIS | AGENT WITHAFERIN | proliferation | withaferin A | MECHANISMS | Glioblastoma multiforme | TEMOZOLOMIDE | pleiotropic drugs | invasion | ONCOLOGY | review | migration | motility | TARGETS | INHIBITOR | GLIOMA-CELL MIGRATION | Cell proliferation | Heterogeneity | Chemotherapy | Therapeutic applications | Biological evolution | Glioblastoma | Drug resistance | Cell differentiation | Cell migration | Tumors
Journal Article
Experimental Eye Research, ISSN 0014-4835, 03/2019, Volume 180, pp. 155 - 163
The type III intermediate filament (IF) proteins vimentin and desmin are sequentially overexpressed in stromal myofibroblasts over the period when fibrosis... 
Vimentin | Cell proliferation | Withaferin A | Myofibroblast | Phosphorylated vimentin | Corneal fibrosis | Desmin | Keratin K8 | CELLS | DYNAMICS | ARCHITECTURE | OPHTHALMOLOGY | MICE | INHIBITOR | EXPRESSION | WITHAFERIN | Prevention | Keratin | Medical research | Analysis | Fibrosis | Medicine, Experimental | Muscle proteins
Journal Article
Journal of Ayurveda and Integrative Medicine, ISSN 0975-9476, 2019
Introduction: Withaferin-A (WA), an active principle obtained from a traditional Indian herb known as Ashwagandha or the Indian ginseng, has been shown to... 
Ashwagandha | Safety | Pharmacokinetics | Osteosarcoma | Withaferin-A
Journal Article
European Journal of Pharmacology, ISSN 0014-2999, 2008, Volume 599, Issue 1, pp. 11 - 17
Induction of inducible nitric oxide synthase (iNOS) expression and nitric oxide (NO) production is thought to have beneficial immunomodulatory effects in acute... 
Withaferin A | NF-κB | iNOS | Akt | Nitric oxide
Journal Article
Journal of Pharmacological Sciences, ISSN 1347-8613, 2014, Volume 125, Issue 1, pp. 83 - 90
Abstract. Increasing evidence supports the role of microRNAs (miRNA) in the regulation of inflammation in various human disorders. Several recent studies have... 
Journal Article
ISSN 0265-0568, 4/2015, Volume 32, Issue 5, pp. 75 - 722
Covering: 1970-2014 ER stress has been identified as a hallmark, and sometimes trigger, of several pathologies, notably cancer, inflammation and... 
Journal Article
Journal of Biological Chemistry, ISSN 0021-9258, 01/2014, Volume 289, Issue 3, pp. 1852 - 1865
Journal Article
Biochemical pharmacology, ISSN 0006-2952, 08/2019
Despite the recent successes of targeted cancer immuno-therapies, drug resistance and disease relapse remain a huge burden in cancer patient treatment. This... 
Journal Article
Journal of Proteomics, ISSN 1874-3919, 05/2018, Volume 179, pp. 17 - 29
Journal Article