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Oncogene, ISSN 0950-9232, 01/2016, Volume 35, Issue 1, pp. 12 - 21
Journal Article
The EMBO Journal, ISSN 0261-4189, 01/2010, Volume 29, Issue 1, pp. 41 - 54
Journal Article
Cold Spring Harbor Perspectives in Biology, ISSN 1943-0264, 09/2012, Volume 4, Issue 9, pp. a007864 - a007864
Journal Article
Nature, ISSN 0028-0836, 05/2012, Volume 484, Issue 7397, pp. 195 - 202
Journal Article
PLoS Biology, ISSN 1544-9173, 2006, Volume 4, Issue 6, pp. 1000 - 1009
The genes encoding members of the wingless-related MMTV integration site ( WNT) and fibroblast growth factor ( FGF) families coordinate growth, morphogenesis,... 
DETERMINING REGION | NUCLEAR IMPORT | SERTOLI-CELL DIFFERENTIATION | TESTIS DIFFERENTIATION | FACTOR SOX9 | DEVELOPING GONAD | GERM-CELLS | BIOCHEMISTRY & MOLECULAR BIOLOGY | MOUSE | BIOLOGY | EXPRESSION | CHONDROCYTE DIFFERENTIATION | Gonads - embryology | Sex-Determining Region Y Protein - genetics | Fibroblast Growth Factor 9 - physiology | Male | Wnt Proteins - metabolism | Fibroblast Growth Factor 9 - genetics | Gonads - cytology | Sex Determination Processes | Wnt Proteins - genetics | Gene Expression Regulation, Developmental | Female | Proto-Oncogene Proteins - metabolism | High Mobility Group Proteins - metabolism | Signal Transduction | Proto-Oncogene Proteins - genetics | Transcription Factors - genetics | Fibroblast Growth Factor 9 - metabolism | Transcription Factors - metabolism | Gonads - metabolism | Animals | Proto-Oncogene Proteins - physiology | Sex-Determining Region Y Protein - metabolism | Mice | Wnt Proteins - physiology | Mutation | SOX9 Transcription Factor | Wnt4 Protein | High Mobility Group Proteins - genetics | High Mobility Group Proteins | Sex-Determining Region Y Protein | Biochemistry, Molecular Biology | Wnt Proteins | Life Sciences | Transcription Factors | Proto-Oncogene Proteins | Gonads | Fibroblast Growth Factor 9 | Development | Mus (Mouse) | Vertebrates | Mammals | Cell Biology | Cell culture | Experiments | Insulin | Embryos | Rodents | Genes
Journal Article
Science, ISSN 0036-8075, 7/2012, Volume 337, Issue 6090, pp. 59 - 64
Journal Article
Nucleic Acids Research, ISSN 0305-1048, 03/2011, Volume 39, Issue 5, pp. 1880 - 1893
The Epstein-Barr virus (EBV) is an oncogenic human Herpes virus found in similar to 15% of diffuse large B-cell lymphoma (DLBCL). EBV encodes miRNAs and... 
TRANSCRIPTION FACTORS | MIR-155 | ACTIVATION | MESSENGER-RNA | GENE | INDUCED CYTIDINE DEAMINASE | BIOCHEMISTRY & MOLECULAR BIOLOGY | ACUTE LYMPHOBLASTIC-LEUKEMIA | EXPRESSION PROFILES | BETA-CATENIN | C-MYB PROTOONCOGENE | Herpesvirus 4, Human - genetics | Humans | Gene Expression Regulation, Neoplastic | Proto-Oncogene Proteins c-myb - genetics | MicroRNAs - metabolism | Gene Expression Profiling | Wnt Proteins - metabolism | Epstein-Barr Virus Infections - genetics | RNA, Small Untranslated - genetics | Nuclear Proteins - genetics | Binding Sites | Cell Line | Epstein-Barr Virus Infections - virology | Gene Library | Molecular Sequence Annotation | Ubiquitin-Protein Ligases - metabolism | Nuclear Proteins - metabolism | Proto-Oncogene Proteins - genetics | DNA-Binding Proteins - genetics | Reverse Transcriptase Polymerase Chain Reaction | beta Catenin - metabolism | Lymphoma, Large B-Cell, Diffuse - virology | Proto-Oncogene Proteins c-myb - metabolism | MicroRNAs - genetics | Herpesvirus 4, Human - metabolism | Ubiquitin-Protein Ligases - genetics | Lymphoma, Large B-Cell, Diffuse - genetics | Lymphoma, Large B-Cell, Diffuse | beta Catenin | Wnt Proteins | Proto-Oncogene Proteins c-myb | Herpesvirus 4, Human | Nuclear Proteins | Ubiquitin-Protein Ligases | Life Sciences | MicroRNAs | Proto-Oncogene Proteins | RNA, Small Untranslated | Epstein-Barr Virus Infections | DNA-Binding Proteins | Cancer | RNA
Journal Article
Nature, ISSN 0028-0836, 2012, Volume 488, Issue 7413, pp. 665 - 669
LGR5+ stem cells reside at crypt bottoms, intermingled with Paneth cells that provide Wnt, Notch and epidermal growth factor signals. Here we find that the... 
IN-VITRO | INHIBITION | MULTIDISCIPLINARY SCIENCES | TRANSCRIPTION | UBIQUITYLATION | SMALL-INTESTINE | COLON | BETA-CATENIN | LGR5 | CANCER | NEGATIVE REGULATOR | Oncogene Proteins - genetics | Receptors, Wnt - antagonists & inhibitors | Cell Proliferation | Receptors, G-Protein-Coupled - metabolism | Humans | Ubiquitin - metabolism | Paneth Cells - pathology | Stem Cells - cytology | Receptors, Wnt - metabolism | Stem Cells - metabolism | DNA-Binding Proteins - deficiency | Adenoma - metabolism | DNA-Binding Proteins - metabolism | Endocytosis | Ubiquitination | Lysosomes - metabolism | Stem Cells - enzymology | Tumor Suppressor Proteins - deficiency | Organoids - metabolism | Tumor Suppressor Proteins - genetics | HEK293 Cells | Colorectal Neoplasms - metabolism | Paneth Cells - metabolism | Tumor Suppressor Proteins - metabolism | Organoids - pathology | Oncogene Proteins - metabolism | Organoids - cytology | Ubiquitin-Protein Ligases - metabolism | Frizzled Receptors - metabolism | DNA-Binding Proteins - genetics | beta Catenin - metabolism | Animals | Wnt Signaling Pathway - drug effects | Adenoma - pathology | Ubiquitin-Protein Ligases - deficiency | Oncogene Proteins - deficiency | Mice | Receptors, G-Protein-Coupled - genetics | Colorectal Neoplasms - pathology | Ubiquitin-Protein Ligases - genetics | Ubiquitin | Colorectal cancer | Physiological aspects | Development and progression | Research | Gene expression | Risk factors | Proteins | Epidermal growth factor | Mutation | Kinases | Rodents | Stem cells
Journal Article
Cell, ISSN 0092-8674, 2001, Volume 107, Issue 4, pp. 513 - 523
In humans, low peak bone mass is a significant risk factor for osteoporosis. We report that LRP5, encoding the low-density lipoprotein receptor-related protein... 
MINERAL DENSITY | BIOCHEMISTRY & MOLECULAR BIOLOGY | MOUSE | OSTEOBLAST LINEAGE | MOLECULAR-CLONING | MICE | DIFFERENTIATION | BETA-CATENIN | OSTEOPOROSIS | CELL-DEATH | FAMILY | CELL BIOLOGY | Wnt2 Protein | Humans | Child, Preschool | Male | Bone Density - genetics | Wnt Proteins | Mesoderm - cytology | Wnt-5a Protein | Eye - embryology | Osteoporosis - genetics | Animals, Outbred Strains | Dishevelled Proteins | Bone Morphogenetic Proteins - pharmacology | Child | Organ Culture Techniques | Transforming Growth Factor beta | Signal Transduction | Chromosomes, Human, Pair 11 - genetics | Adaptor Proteins, Signal Transducing | Skull - cytology | Wnt3 Protein | Mice | Receptors, LDL - physiology | COS Cells | Species Specificity | LDL-Receptor Related Proteins | DNA, Complementary - genetics | Recombinant Fusion Proteins - physiology | Cercopithecus aethiops | Culture Media, Conditioned - pharmacology | Recombinant Proteins | Transfection | Receptors, LDL - deficiency | Stromal Cells - drug effects | Adult | Female | Phosphoproteins - physiology | Proteins - physiology | Receptors, LDL - genetics | Bone Morphogenetic Protein 2 | Low Density Lipoprotein Receptor-Related Protein-5 | Mice, Inbred C57BL | Zebrafish Proteins | Proto-Oncogene Proteins - genetics | Phosphoproteins - genetics | Eye Abnormalities - genetics | Genes, Recessive | Syndrome | Proteins - genetics | Animals | Proto-Oncogene Proteins - physiology | Heterozygote | Osteoblasts - metabolism | Stromal Cells - cytology | Wnt4 Protein | Osteoporosis | Bones | Density | Low density lipoproteins | Proteins | Cell research | Lipoproteins | Growth | Analysis | Physiological aspects | Receptors, LDL | Mesoderm | Osteoblasts | Recombinant Fusion Proteins | Eye | Life Sciences | Stromal Cells | Eye Abnormalities | Phosphoproteins | Proto-Oncogene Proteins | Bone Density | Biochemistry, Molecular Biology | Culture Media, Conditioned | Skull | Chromosomes, Human, Pair 11 | Bone Morphogenetic Proteins | DNA, Complementary
Journal Article
Molecular Cell, ISSN 1097-2765, 2003, Volume 12, Issue 5, pp. 1251 - 1260
The cytoplasmic protein Dishevelled (Dvl) and the associated membrane-bound receptor Frizzled (Fz) are essential in canonical and noncanonical Wnt signaling... 
PATHWAYS | COMPLEX | PROTEIN | RECOGNITION | SPECIFICITY | STRUCTURAL BASIS | BIOCHEMISTRY & MOLECULAR BIOLOGY | WNT SIGNAL-TRANSDUCTION | BETA-CATENIN | DROSOPHILA | PLANAR CELL-POLARITY | CELL BIOLOGY
Journal Article
Genes and Development, ISSN 0890-9369, 01/2003, Volume 17, Issue 2, pp. 295 - 309
Wnt/Frizzled (Fz) signaling controls cell polarity/movements during vertebrate gastrulation via incompletely defined mechanisms. We demonstrated previously... 
Rho | Vertebrates | Gastrulation | Frizzled | Wnt | Rac | HUMAN NEUTROPHILS | TISSUE POLARITY | PLANAR CELL POLARITY | DEVELOPMENTAL BIOLOGY | MAMMALIAN-CELLS | vertebrates | DROSOPHILA EYE | XENOPUS-LAEVIS | CONVERGENT EXTENSION MOVEMENTS | MAMMARY ONCOGENE | GENETICS & HEREDITY | ACTIN CYTOSKELETON | gastrulation | Xenopus - genetics | Humans | rac GTP-Binding Proteins - metabolism | Wnt Proteins | Phosphoproteins - metabolism | Xenopus - embryology | Cell Movement - genetics | Cell Movement - physiology | RNA - genetics | rac GTP-Binding Proteins - genetics | JNK Mitogen-Activated Protein Kinases | Drosophila - embryology | Dishevelled Proteins | Drosophila - genetics | RNA - metabolism | Frizzled Receptors | Proto-Oncogene Proteins - metabolism | Cell Line | Drosophila Proteins | Signal Transduction | rho GTP-Binding Proteins - genetics | Zebrafish Proteins | Proto-Oncogene Proteins - genetics | Gastrula - cytology | Phosphoproteins - genetics | Xenopus Proteins | Proteins - genetics | Cell Polarity - genetics | Adaptor Proteins, Signal Transducing | Animals | Proteins - metabolism | Xenopus - metabolism | Models, Biological | rho GTP-Binding Proteins - metabolism | Cell Polarity - physiology | Gastrula - metabolism | Drosophila - metabolism | Mitogen-Activated Protein Kinases - metabolism | Morphogenesis | Analysis | Genetic research | Physiological aspects | Genetic aspects | Genetic regulation | Cells | rac protein | Wnt protein | Frizzled protein | Dishevelled protein | Research Paper
Journal Article