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Annals of Dermatology, ISSN 1013-9087, 2016, Volume 28, Issue 1, p. 45
Background: Psoriasis is characterized by uncontrolled hyperproliferation, aberrant differentiation, and dermal infiltration of immune cells. Recent studies... 
Psoriasis | Wnt5a | Notch1
Journal Article
Biochemical and Biophysical Research Communications, ISSN 0006-291X, 01/2019, Volume 509, Issue 1, pp. 201 - 208
The human enhancer of filamentation 1 (HEF1) is a multi-domain docking protein of the p130 Cas family. Research reports on the mechanism of HEF1 in gastric... 
HEF1 | Cancer differentiation | Gastric cancer | Wnt5a/β-catenin signaling pathway | MIGRATION | APOPTOSIS | CELLS | METASTASIS | PROTEIN | BIOCHEMISTRY & MOLECULAR BIOLOGY | NEDD9 | INVASION | BIOPHYSICS | Wnt5a/beta-catenin signaling pathway | EXPRESSION | PROMOTES
Journal Article
Medical Journal of Chinese People's Liberation Army, ISSN 0577-7402, 2018, Volume 43, Issue 4, pp. 316 - 321
Journal Article
Cell Structure and Function, ISSN 0386-7196, 2017
The submandibular gland (SMG) is one of the major salivary glands that play important roles for variety of physiological functions, such as digestion of foods,... 
Wnt5a | inflammation | fibrosis | Ror2 | submandibular gland
Journal Article
Cell Stem Cell, ISSN 1934-5909, 06/2018, Volume 22, Issue 6, pp. 951 - 959.e3
Cirmtuzumab is a humanized monoclonal antibody (mAb) that targets ROR1, an oncoembryonic orphan receptor for Wnt5a found on cancer stem cells (CSCs). Aberrant... 
WNT5A INDUCES ROR1 | CHEMOTAXIS | RITUXIMAB | HS1 | C-MYC | SELF-RENEWAL | RECEPTOR | CELL | EXPRESSION | CANCER | CELL & TISSUE ENGINEERING | CELL BIOLOGY
Journal Article
BBA - Molecular and Cell Biology of Lipids, ISSN 1388-1981, 02/2020, Volume 1865, Issue 2, p. 158547
Atherosclerosis (AS) is characterized by lipids metabolism disorder and inflammatory response. Accumulating evidence has demonstrated that Wingless type 5a... 
Vascular smooth muscle cell | Cholesterol homeostasis,Inflammatory response | Wnt5a/Ror2 pathway | Atherosclerosis
Journal Article
Oncotarget, ISSN 1949-2553, 06/2018, Volume 9, Issue 43, pp. 27293 - 27304
Prostate cancer is the most common malignancy in men and has a high propensity to metastasize to bone. WNT5A has recently been implicated in the progression of... 
Wnt receptors | Frizzled | RYK | Prostate cancer | WNT5A
Journal Article
Lasers in Surgery and Medicine, ISSN 0196-8092, 12/2017, Volume 49, Issue 10, pp. 940 - 947
Background Outer root sheath cells (ORSCs) play important roles in maintaining hair follicle structure and provide support for the bulge area. The hair growth... 
photobiomodulation therapy | hair growth promoting effect | Wnt5a/β‐catenin pathway | ERK signaling pathway | outer root sheath cell | light‐emitting diode irradiation | light-emitting diode irradiation | Wnt5a/β-catenin pathway
Journal Article
Cell Structure and Function, ISSN 0386-7196, 2017, Volume 42, Issue 2, pp. 159 - 167
The submandibular gland (SMG) is one of the major salivary glands that play important roles for variety of physiological functions, such as digestion of foods,... 
fibrosis | Ror2 | Wnt5a | submandibular gland | inflammation | Submandibular gland | Inflammation | Fibrosis
Journal Article
CANCER RESEARCH, ISSN 0008-5472, 09/2019, Volume 79, Issue 18, pp. 4599 - 4611
Chemoresistance is driven by unique regulatory networks in the genome that are distinct from those necessary for cancer development. Here, we investigate the... 
TRANSFORMATION | SUPER-ENHANCERS | ONCOLOGY | WNT/BETA-CATENIN | PATHWAY | CELL IDENTITY | WNT5A | TUMOR | CISPLATIN RESISTANCE | GENOME-WIDE | SOX9
Journal Article
Journal of Bone and Mineral Research, ISSN 0884-0431, 03/2012, Volume 27, Issue 3, pp. 575 - 585
Journal Article
Oncology Letters, ISSN 1792-1074, 12/2017, Volume 14, Issue 6, pp. 7197 - 7200
The objective of this study was to investigate the mechanism of the function of Wnt signaling pathway in regulating autophagy and inflammatory response in... 
Inflammatory response | Autophagy | Glioma cells | Wnt5a/β-catenin signaling pathway | TARGET | CELLS | autophagy | inflammatory response | glioma cells | PROLIFERATION | TUMORS | MTOR | TRANSITION | ONCOLOGY | COLORECTAL-CANCER | Wnt5a/beta-catenin signaling pathway | STRESS | EXPRESSION | BRAIN
Journal Article
CARCINOGENESIS, ISSN 0143-3334, 04/2014, Volume 35, Issue 4, pp. 784 - 794
WNT5A has been identified as an important ligand in the malignant progression of a number of tumours. Although WNT5A signalling is often altered in cancer, the... 
GLYCOLYSIS | OXIDATIVE-PHOSPHORYLATION | INVASION | PROTEIN | METASTASIS | ONCOLOGY | WNT5A EXPRESSION | DISTINCT | TARGETS | MELANOMA PROGRESSION | TUMORS
Journal Article
by Luo, M and Zhou, L and Zhan, SJ and Cheng, LJ and Li, RN and Wang, H and Liu, B and Linghu, H
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, ISSN 0006-291X, 05/2019, Volume 513, Issue 2, pp. 528 - 533
The ALPL gene is linked to hypophosphatasia, a rare genetic disease. Owing to the inverse relationships between ALPL expression and both the International... 
WNT5A-FZD2-STAT3 axis | Motility | Prognosis | BIOPHYSICS | BIOCHEMISTRY & MOLECULAR BIOLOGY | GROWTH | ALPL | TARGETS | MESENCHYMAL TRANSITION | EMT | Ovarian cancer | PLASTICITY
Journal Article
Cell, ISSN 0092-8674, 11/2014, Volume 159, Issue 4, pp. 844 - 856
Wnt signaling plays a critical role in embryonic development, and genetic aberrations in this network have been bro