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Clinical Cancer Research, ISSN 1078-0432, 08/2014, Volume 20, Issue 16, pp. 4228 - 4239
Purpose: We performed a phase I trial to investigate the safety, clinical responses, and Wilms' tumor 1 (WT1)-specific immune responses following treatment... 
PROTEIN | ONCOLOGY | WT1 PEPTIDE VACCINE | CD4(+) T-CELLS | ANTIGENS | INDUCTION | IDENTIFICATION | HELPER PEPTIDE | EXPRESSION | GENE WT1 | GEMCITABINE | Carcinoma, Pancreatic Ductal - secondary | Prognosis | Follow-Up Studies | Dendritic Cells - immunology | Humans | Middle Aged | Vaccination | Male | Epitopes - immunology | Bile Duct Neoplasms - immunology | Deoxycytidine - therapeutic use | Peptide Fragments - immunology | WT1 Proteins - immunology | Adult | Carcinoma, Pancreatic Ductal - mortality | Female | Pancreatic Neoplasms - mortality | Carcinoma, Pancreatic Ductal - immunology | T-Lymphocytes, Cytotoxic - immunology | Cholangiocarcinoma - therapy | Biomarkers, Tumor - analysis | Cholangiocarcinoma - secondary | Adenocarcinoma - immunology | Bile Duct Neoplasms - secondary | Pancreatic Neoplasms - pathology | Cholangiocarcinoma - mortality | Histocompatibility Antigens Class I - immunology | Cholangiocarcinoma - immunology | Survival Rate | Carcinoma, Pancreatic Ductal - therapy | Combined Modality Therapy | Adenocarcinoma - secondary | Antimetabolites, Antineoplastic - therapeutic use | Bile Duct Neoplasms - therapy | Histocompatibility Antigens Class II - immunology | Adenocarcinoma - therapy | Bile Duct Neoplasms - mortality | Pancreatic Neoplasms - immunology | Aged | CD8-Positive T-Lymphocytes - immunology | Neoplasm Staging | Bile Ducts, Intrahepatic - immunology | Deoxycytidine - analogs & derivatives | Adenocarcinoma - mortality | Pancreatic Neoplasms - therapy
Journal Article
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 8/2010, Volume 107, Issue 31, pp. 13824 - 13829
Journal Article
Blood, ISSN 0006-4971, 07/2010, Volume 116, Issue 2, pp. 171 - 179
Journal Article
Clinical Immunology, ISSN 1521-6616, 2015, Volume 168, pp. 6 - 15
Abstract In the present study, the combined adjuvant effect of 7DW8-5, a potent α-GalCer-analog, and MPLA, a TLR4 agonist, on the induction of vaccine-induced... 
Allergy and Immunology | Cancer vaccine | NKT cells | Malaria vaccine | Memory-like effector NKT cells | WT-1 | Adjuvant | CD1d | TLR4 | Circumsporozoite protein | Glycolipid | GENE WT1 PRODUCT | DENDRITIC CELLS | IMMUNOLOGY | CANCER | TUMOR-IMMUNITY | PROTECTIVE IMMUNITY | IMMUNE-RESPONSES | IN-VIVO | TOLL-LIKE RECEPTORS | MICE | HLA-A2 Antigen - genetics | Humans | Lipid A - analogs & derivatives | Interferon-gamma - metabolism | Galactosylceramides - administration & dosage | Galactosylceramides - pharmacology | Protective Agents - pharmacology | WT1 Proteins - immunology | CD8-Positive T-Lymphocytes - metabolism | Killer Cells, Natural - immunology | Toll-Like Receptor 4 - agonists | Protozoan Proteins - chemistry | Epitopes, T-Lymphocyte - immunology | WT1 Proteins - genetics | Immunologic Memory - immunology | Amino Acid Sequence | Lipid A - administration & dosage | Plasmodium yoelii - physiology | HLA-A2 Antigen - immunology | Immunization - methods | Malaria - immunology | Mice, Inbred C57BL | Peptides - immunology | Mice, Transgenic | Plasmodium yoelii - immunology | Toll-Like Receptor 4 - metabolism | Drug Synergism | Malaria - prevention & control | Models, Immunological | Animals | CD8-Positive T-Lymphocytes - drug effects | Interferon-gamma - immunology | Lipid A - pharmacology | Malaria - parasitology | Cell Line, Tumor | Killer Cells, Natural - drug effects | Mice, Inbred BALB C | Killer Cells, Natural - metabolism | Protective Agents - administration & dosage | CD8-Positive T-Lymphocytes - immunology | Protozoan Proteins - immunology
Journal Article
Blood, ISSN 0006-4971, 2009, Volume 113, Issue 26, pp. 6541 - 6548
Journal Article
Nature Communications, ISSN 2041-1723, 2014, Volume 5, Issue 1, p. 5852
Angiogenesis, activation of metastasis and avoidance of immune destruction are important for cancer progression. These biological capabilities are, apart from... 
MIGRATION | CELLS | IN-VITRO | ACTIVATION | METASTASIS | GENE | LUNG-CARCINOMA | MULTIDISCIPLINARY SCIENCES | TRANSCRIPTION | EXPRESSION | ENDOTHELIAL GROWTH-FACTOR | Neoplasm Transplantation | RNA, Small Interfering - genetics | Platelet Endothelial Cell Adhesion Molecule-1 - genetics | Humans | Gene Expression Regulation, Neoplastic | WT1 Proteins - antagonists & inhibitors | Hematopoietic Stem Cells - pathology | Proto-Oncogene Proteins c-kit - immunology | Platelet Endothelial Cell Adhesion Molecule-1 - immunology | Neovascularization, Pathologic - pathology | Hematopoietic Stem Cells - immunology | Melanoma, Experimental - immunology | Myeloid Cells - immunology | Skin Neoplasms - mortality | WT1 Proteins - immunology | Female | Proto-Oncogene Proteins c-kit - genetics | Neovascularization, Pathologic - immunology | Skin Neoplasms - blood supply | Tumor Cells, Cultured | WT1 Proteins - genetics | Melanoma, Experimental - blood supply | Melanoma, Experimental - mortality | Signal Transduction | Skin Neoplasms - immunology | Mice, Transgenic | Tumor Burden | Gene Knockout Techniques | Immunity, Innate | Disease Progression | Endothelial Cells - immunology | Animals | Melanoma, Experimental - genetics | Skin Neoplasms - genetics | Survival Analysis | Neovascularization, Pathologic - genetics | Mice | Myeloid Cells - pathology | Endothelial Cells - pathology | RNA, Small Interfering - metabolism
Journal Article
Journal Article
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 9/2004, Volume 101, Issue 38, pp. 13885 - 13890
Journal Article
Journal Article
Blood, ISSN 0006-4971, 03/2011, Volume 117, Issue 9, pp. 2691 - 2699
Journal Article
Journal Article
Haematologica, ISSN 0390-6078, 03/2011, Volume 96, Issue 3, pp. 432 - 440
Journal Article