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The Journal of biological chemistry, ISSN 0021-9258, 01/2014, Volume 289, Issue 2, pp. 1128 - 1141
beta-Arrestin is a scaffold protein that regulates signal transduction by seven transmembrane-spanning receptors. Among other functions it is also critically... 
Life Sciences & Biomedicine | Biochemistry & Molecular Biology | Science & Technology | Wnt3A Protein - metabolism | Phosphorylation | Minor Histocompatibility Antigens | Humans | Arrestins - genetics | Phosphoproteins - metabolism | Arrestins - metabolism | Low Density Lipoprotein Receptor-Related Protein-6 - genetics | Phosphatidylinositol 4,5-Diphosphate - metabolism | RNA Interference | Tumor Suppressor Proteins - genetics | HEK293 Cells | Cell Membrane - metabolism | Dishevelled Proteins | Fibroblasts - metabolism | Tumor Suppressor Proteins - metabolism | Wnt3A Protein - genetics | Cells, Cultured | Phosphotransferases (Alcohol Group Acceptor) - genetics | Phosphoproteins - genetics | Blotting, Western | Mice, Knockout | Phosphotransferases (Alcohol Group Acceptor) - metabolism | Microscopy, Confocal | Low Density Lipoprotein Receptor-Related Protein-6 - metabolism | Animals | Embryo, Mammalian - cytology | beta-Arrestins | Adaptor Proteins, Signal Transducing - genetics | Protein Binding | Fibroblasts - cytology | Mice | Adaptor Proteins, Signal Transducing - metabolism | Index Medicus | Wnt Signaling | Lrp6 Phosphorylation | β-Arrestin | Phosphatidylinositol Signaling | Cell Biology | Phosphatidylinositol Kinase | FAM123B | Phosphatidylinositol Phosphate Kinase | β-Catenin | Membrane Lipids | WTX | Dvl | Amer1
Journal Article
Cell discovery, ISSN 2056-5968, 07/2015, Volume 1, Issue 1, pp. 15016 - 15016
The tumor suppressor APC employs its conserved armadillo repeat (ARM) domain to recognize many of its binding partners, including Amer1/WTX, which is mutated... 
Consensus recognition mode | WTX | APC | Amer1 | ARM domain | Crystal structure
Journal Article
Oncogene, ISSN 0950-9232, 02/2009, Volume 28, Issue 8, pp. 1063 - 1075
Wilms tumours (WTs) have two distinct types of histology with or without ectopic mesenchymal elements, suggesting that WTs arise from either the mesenchymal or... 
Mesenchymal stem cell | Cancer stem cell | Nephrogenic rest | WTX | Multiplex ligation-dependent probe amplification | Biochemistry & Molecular Biology | Oncology | Genetics & Heredity | Life Sciences & Biomedicine | Science & Technology | Cell Biology | Genomic Imprinting | Kidney Neoplasms - genetics | WT1 Proteins - metabolism | Oligonucleotide Array Sequence Analysis | Wilms Tumor - genetics | Humans | Gene Expression Regulation, Neoplastic | Male | Gene Expression Profiling | Kidney Neoplasms - metabolism | Mesoderm - cytology | Loss of Heterozygosity | Wnt Proteins - metabolism | Nephrons - cytology | Cell Nucleus - metabolism | Insulin-Like Growth Factor II - genetics | Wnt Proteins - genetics | Gene Deletion | Tumor Suppressor Proteins - genetics | Female | Cell Differentiation | Wilms Tumor - metabolism | WT1 Proteins - genetics | Epithelium - pathology | Tumor Suppressor Proteins - metabolism | Epithelium - metabolism | Signal Transduction | Chromosomes, Human, Pair 11 - genetics | Mutation - genetics | beta Catenin - metabolism | Insulin-Like Growth Factor II - metabolism | beta Catenin - genetics | Cell Lineage | Adaptor Proteins, Signal Transducing | Mesoderm - metabolism | Nephrons - metabolism | Cellular signal transduction | Genetic aspects | Research | Nephroblastoma | Health aspects | Cell lines | Signal transduction | Genetics | Histology | Tumors | Index Medicus
Journal Article
Journal of experimental & clinical cancer research, ISSN 1756-9966, 01/2020, Volume 39, Issue 1, pp. 1 - 212
Background The X-linked gene WTX (also called AMER1) has been reported to function as a tumour suppressor gene in Wilms’ tumour. In our previous study, WTX... 
Medical research | Wound healing | Statistical analysis | Mortality | Antibodies | X chromosomes | Gene expression | Kinases | Cancer therapies | Stomach cancer | Cell adhesion & migration | Proteins | Cell growth | MicroRNAs | Cell cycle | Tumorigenesis | Mutation | Thermal cycling | Index Medicus | WTX/AMER1 | Gastric cancer | miR-20a-5p | PI3K/AKT
Journal Article