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Journal of Biological Chemistry, ISSN 0021-9258, 10/1998, Volume 273, Issue 42, pp. 27587 - 27592
Journal Article
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 1/2011, Volume 108, Issue 4, pp. 1525 - 1530
Modulation of DNA repair proteins by small molecules has attracted great interest. An in vitro helicase activity screen was used to identify molecules that... 
Molecules | Cell growth | DNA | DNA damage | Cell nucleus | Cell lines | HeLa cells | Werner syndrome | DNA repair | Apoptosis | Human disease | Genomic instability | POLY(ADP-RIBOSE) POLYMERASE | CELLS | FORK | RECQ HELICASES | human disease | TELOMESTATIN | MULTIDISCIPLINARY SCIENCES | CANCER-THERAPY | SUBSTRATE-SPECIFICITY | IN-VITRO | REPAIR | DISSOCIATION | genomic instability | Apoptosis - drug effects | DNA Replication - drug effects | RecQ Helicases - metabolism | Humans | Werner Syndrome Helicase | Maleimides - pharmacology | Exodeoxyribonucleases - antagonists & inhibitors | Immunoblotting | RecQ Helicases - genetics | Dose-Response Relationship, Drug | Topoisomerase I Inhibitors - pharmacology | Time Factors | Enzyme Inhibitors - chemistry | Molecular Structure | Stress, Physiological - drug effects | Exodeoxyribonucleases - genetics | DNA Damage - drug effects | Cell Line | Cell Survival - drug effects | Topotecan - pharmacology | Enzyme Inhibitors - pharmacology | Adenosine Triphosphatases - metabolism | Drug Synergism | Adenosine Triphosphatases - antagonists & inhibitors | RecQ Helicases - antagonists & inhibitors | Exodeoxyribonucleases - metabolism | Cell Line, Tumor | Cell Proliferation - drug effects | Oxazoles - pharmacology | S Phase - drug effects | HeLa Cells | Histones - metabolism | Maleimides - chemistry | Proliferating Cell Nuclear Antigen - metabolism | DNA replication | Research | Helicases | Biological Sciences
Journal Article
2001, Gann monograph on cancer research, ISBN 9783805571586, Volume no. 49., x, 168
Book
Nucleic Acids Research, ISSN 0305-1048, 2006, Volume 34, Issue 8, pp. 2269 - 2279
Journal Article
Cancer Research, ISSN 0008-5472, 09/2013, Volume 73, Issue 17, pp. 5497 - 5507
Journal Article
PLoS ONE, ISSN 1932-6203, 10/2015, Volume 10, Issue 10, p. e0140292
Werner syndrome (WS) is a premature aging disorder caused by mutations in a RecQ-family DNA helicase, WRN. Mice lacking part of the helicase domain of the WRN... 
CELLS | OXIDATIVE STRESS | INSULIN-RESISTANCE | INFLAMMATION | MULTIDISCIPLINARY SCIENCES | POLY(ADP-RIBOSE) POLYMERASE-1 | SYNDROME GENE | ASCORBIC-ACID | EXPRESSION | PLASMINOGEN-ACTIVATOR INHIBITOR | FIBROBLASTS | Endoplasmic Reticulum - enzymology | Reactive Oxygen Species - metabolism | Oxidative Stress | Mice, Inbred C57BL | Werner Syndrome Helicase | Cells, Cultured | Werner Syndrome - blood | Male | RecQ Helicases - genetics | Werner Syndrome - enzymology | Autophagy | Mice, Knockout | Protein Transport | Phenotype | Animals | Werner Syndrome - genetics | Female | Mutation | Cytokines | Metabolites | Gene mutations | Analysis | Genetic aspects | Werner syndrome | Risk factors | Liver | Cardiovascular disease | Tissue analysis | Blood | Proteins | Genotype & phenotype | Fibroblasts | Aging | Physiology | Deoxyribonucleic acid--DNA | Abnormalities | Mass spectroscopy | Metabolism | Organelles | Embryos | RecQ protein | Interleukin 18 | Werner's syndrome | Morphology | Interleukin 10 | Mice | Cardiovascular diseases | Mass spectrometry | Endoplasmic reticulum | Phagocytosis | Oxidative stress | Hydroxyproline | Chains | Amino acids | DNA helicase | Rodents | DNA methylation | Extracellular matrix | Age | Phenotypes | WRN protein | Markers | Health risks | Inflammation | Embryo fibroblasts | Vascular system | Mutants | Medicine | Life span | Plasminogen activator inhibitors | Epigenetics | Diabetes | Laboratory animals | Deoxyribonucleic acid | DNA
Journal Article