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Journal Article
European Journal of Dermatology, ISSN 1167-1122, 05/2012, Volume 22, Issue 3, pp. 299 - 309
Basal cell carcinoma (BCC) is the commonest cancer in humans. Predisposing factors reflect common genetic variations and environmental influences in most... 
Xeroderma pigmentosum | Folliculo-sebaceus unit | Basal cell carcinoma | Gorlin syndrome | Bazex-Dupré-Christol syndrome | Epidermal nevus syndrome | epidermal nevus syndrome | EPIDERMODYSPLASIA-VERRUCIFORMIS | CARTILAGE-HAIR HYPOPLASIA | xeroderma pigmentosum | DUPRE-CHRISTOL-SYNDROME | COARSE SPARSE HAIR | Bazex-Dupre-Christol syndrome | folliculo-sebaceus unit | SCHULZ-PASSARGE SYNDROME | DERMATOLOGY | FOLLICULAR HAMARTOMA SYNDROME | XERODERMA-PIGMENTOSUM | NEVUS SEBACEUS | basal cell carcinoma | ROTHMUND-THOMSON-SYNDROME | PHAKOMATOSIS-PIGMENTOKERATOTICA | Genetic Testing | Carcinoma, Basal Cell - genetics | Xeroderma Pigmentosum - genetics | Humans | Hypotrichosis - genetics | Rothmund-Thomson Syndrome - epidemiology | Carcinoma, Basal Cell - epidemiology | Carcinoma, Skin Appendage - genetics | Skin Diseases, Genetic - genetics | Nevus, Sebaceous of Jadassohn - epidemiology | Skin Diseases, Genetic - epidemiology | Werner Syndrome - genetics | Histiocytoma, Benign Fibrous - epidemiology | Facial Dermatoses - epidemiology | Histiocytoma, Benign Fibrous - genetics | Hamartoma Syndrome, Multiple - genetics | Facial Dermatoses - genetics | Hypotrichosis - epidemiology | Comorbidity | Cyanosis - epidemiology | Cyanosis - genetics | Basal Cell Nevus Syndrome - epidemiology | Xeroderma Pigmentosum - epidemiology | DNA Replication | Skin Neoplasms - epidemiology | Werner Syndrome - epidemiology | Hamartoma Syndrome, Multiple - epidemiology | Rothmund-Thomson Syndrome - genetics | Skin Neoplasms - genetics | Carcinoma, Skin Appendage - epidemiology | Nevus, Sebaceous of Jadassohn - genetics | Basal Cell Nevus Syndrome - genetics | Mutation
Journal Article
Nature Reviews Cancer, ISSN 1474-175X, 03/2003, Volume 3, Issue 3, pp. 169 - 178
RecQ helicases are highly conserved from bacteria to man. Germline mutations in three of the five known family members in humans give rise to debilitating... 
BLOOMS-SYNDROME GENE | TOPOISOMERASE-III-ALPHA | SYNDROME DNA HELICASE | FUNCTIONAL INTERACTION | ONCOLOGY | ROTHMUND-THOMSON-SYNDROME | STALLED REPLICATION FORKS | MISMATCH REPAIR | HOLLIDAY JUNCTIONS | WERNER-SYNDROME PROTEIN | SISTER-CHROMATID EXCHANGES | Species Specificity | Humans | Rothmund-Thomson Syndrome - enzymology | Werner Syndrome Helicase | DNA Repair - physiology | DNA Repair - genetics | Escherichia coli Proteins - physiology | RecQ Helicases | Cell Transformation, Neoplastic - genetics | Werner Syndrome - genetics | DNA Helicases - genetics | Genes, Tumor Suppressor | Protein Structure, Tertiary | Adenosine Triphosphatases - deficiency | Bloom Syndrome - enzymology | DNA Helicases - chemistry | Genetic Predisposition to Disease | Mutagenesis - genetics | DNA Helicases - deficiency | Bloom Syndrome - genetics | Werner Syndrome - enzymology | Mice, Knockout | Protein Interaction Mapping | Rothmund-Thomson Syndrome - genetics | Animals | DNA Replication - physiology | Multienzyme Complexes - physiology | DNA Replication - genetics | Escherichia coli Proteins - genetics | Adenosine Triphosphatases - chemistry | Adenosine Triphosphatases - genetics | Mice | Exodeoxyribonucleases | Adenosine Triphosphatases - physiology | DNA Helicases - physiology | Gene mutations | Physiological aspects | Genetic aspects | Research | Health aspects | Helicases | Cancer
Journal Article
NATURE COMMUNICATIONS, ISSN 2041-1723, 11/2019, Volume 10, Issue 1, pp. 5284 - 18
Journal Article
Journal Article
The Lancet, ISSN 0140-6736, 08/2003, Volume 362, Issue 9382, pp. 440 - 445
Journal Article
Science, ISSN 0036-8075, 06/2015, Volume 348, Issue 6239, pp. 1160 - 1163
Werner syndrome (WS) is a premature aging disorder caused by WRN protein deficiency. Here, we report on the generation of a human WS model in human embryonic... 
DEFECTS | COMPLEX | WRN | GENE | IPSCS | MULTIDISCIPLINARY SCIENCES | DISEASE | Physiological aspects | Aging | Chromatin | Werner syndrome | Health aspects | Stem cells | Proteins | Genetic disorders | Cellular | Alterations | Disorders | Determinants | Maintenance | Anchoring
Journal Article
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