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Eye (Basingstoke), ISSN 0950-222X, 05/2017, Volume 31, Issue 5, pp. 810 - 813
Purpose To investigate complement activation in aqueous humor and in plasma of patients with neovascular age-related macular degeneration (nAMD). Patients and... 
DRUSEN | HYPOTHESIS | COMPONENTS | OPHTHALMOLOGY | FACTOR-H POLYMORPHISM | RISK | VARIANT | DEFICIENCY | Aqueous Humor - metabolism | Complement Factor H - metabolism | Prospective Studies | Complement Activation | Enzyme-Linked Immunosorbent Assay | Macular Degeneration - genetics | Wet Macular Degeneration - metabolism | Humans | Female | Male | Aged | Index Medicus | Laboratory Study
Journal Article
Journal Article
Investigative Ophthalmology and Visual Science, ISSN 0146-0404, 10/2017, Volume 58, Issue 12, pp. 5065 - 5075
PURPOSE. This study was designed to evaluate effects of fenofibric acid (Feno-FA), a peroxisome proliferator-activated receptor-alpha (PPAR alpha) agonist, on... 
Fenofibrate | Retina | Inflammation | Neovascularization | PPARα | Age-related macular degeneration | WNT SIGNALING PATHWAY | DIABETIC-RETINOPATHY | SUBRETINAL NEOVASCULARIZATION | neovascularization | PPAR alpha | RETINAL ANGIOMATOUS PROLIFERATION | ACTIVATED RECEPTORS | PATHOGENIC ROLE | DENSITY LIPOPROTEIN RECEPTOR | inflammation | retina | TISSUE DISTRIBUTION | OPHTHALMOLOGY | fenofibrate | age-related macular degeneration | EXPRESSION | Tumor Necrosis Factor-alpha - metabolism | Capillary Permeability | Male | Vascular Endothelial Growth Factor A - metabolism | Fenofibrate - therapeutic use | Rats, Inbred BN | Choroidal Neovascularization - drug therapy | Choroidal Neovascularization - pathology | Wet Macular Degeneration - metabolism | Disease Models, Animal | Fluorescein Angiography | Receptors, LDL - genetics | Tomography, Optical Coherence | Wet Macular Degeneration - pathology | Mice, Inbred C57BL | Injections, Intraperitoneal | Fenofibrate - analogs & derivatives | Rats | Receptors, LDL - metabolism | PPAR alpha - genetics | Blotting, Western | Mice, Knockout | Intercellular Adhesion Molecule-1 - metabolism | Animals | Choroidal Neovascularization - metabolism | Wet Macular Degeneration - drug therapy | Leukostasis | PPAR alpha - agonists | Hypolipidemic Agents - therapeutic use | Mice | PPAR alpha - metabolism | Index Medicus | Physiology and Pharmacology
Journal Article
Journal Article
Journal Article
PLoS ONE, ISSN 1932-6203, 05/2014, Volume 9, Issue 5, pp. e96895 - e96895
Background: There is absence of specific biomarkers and an incomplete understanding of the pathophysiology of exudative age-related macular degeneration (AMD).... 
TRANSFERRIN | PROLIFERATIVE DIABETIC-RETINOPATHY | MULTIDISCIPLINARY SCIENCES | AQUEOUS-HUMOR | OPHTHALMOLOGY | RHEOPHERESIS | DISORDERS | CHOROIDAL NEOVASCULARIZATION | PROTEINS | EXPRESSION | DISCOVERY | Humans | Middle Aged | Male | Wet Macular Degeneration - genetics | Case-Control Studies | Bevacizumab | Vitreous Body - chemistry | Wet Macular Degeneration - metabolism | Lipocalins - genetics | Aged, 80 and over | Female | Vitrectomy | Steroids - therapeutic use | Intramolecular Oxidoreductases - metabolism | Peptide Fragments - genetics | Biomarkers - metabolism | Lipocalins - metabolism | Peptide Fragments - metabolism | Antibodies, Monoclonal, Humanized - therapeutic use | alpha 1-Antitrypsin - genetics | Gene Expression Regulation | Fibrinogen - genetics | Wet Macular Degeneration - diagnosis | Intramolecular Oxidoreductases - genetics | Fibrinogen - metabolism | Proteomics | Wet Macular Degeneration - therapy | Aged | alpha 1-Antitrypsin - metabolism | Macular degeneration | Fibrin | Care and treatment | Fibrinogen | Cataracts | Floaters | Glaucoma | Diabetic retinopathy | Blood coagulation | Vitreous humor | Nephrology | Disease | Proteins | Tomography | Degeneration | Bioindicators | Vascular endothelial growth factor | Age | Urine | Immune response | Medical imaging | Capillary electrophoresis | Prostaglandin H2 | Mass spectroscopy | Data processing | Inflammation | Patients | Immune systems | Medicine | Studies | Biomarkers | Scientific imaging | Exudation | Diabetes | Mass spectrometry | Endocrinology | Steroid hormones | Steroids | Index Medicus
Journal Article
Investigative Ophthalmology and Visual Science, ISSN 0146-0404, 01/2017, Volume 58, Issue 1, pp. 292 - 298
Journal Article
Journal Article
Journal Article
Journal Article
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