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1. Full Text Mechanisms and consequences of Jak-STAT signaling in the immune system
by Villarino, Alejandro V and Kanno, Yuka and O'Shea, John J
Nature immunology, ISSN 1529-2908, 03/2017, Volume 18, Issue 4, pp. 374 - 384
Life Sciences & Biomedicine | Immunology | Science & Technology | Genome-Wide Association Study | Multigene Family | Janus Kinases - genetics | Humans | Translational Medical Research | Gene Expression Regulation | STAT Transcription Factors - metabolism | Janus Kinases - metabolism | Molecular Targeted Therapy | STAT Transcription Factors - genetics | Animals | Signal Transduction - drug effects | Immune System - metabolism | Immune System - drug effects | Immune System - immunology | Protein Binding | Physiological aspects | Transcription factors | Research | Gene expression | Immune system | STAT proteins | Index Medicus
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2. Full Text A molecular mechanism of artemisinin resistance in Plasmodium falciparum malaria
by Mbengue, Alassane and Bhattacharjee, Souvik and Pandharkar, Trupti and Liu, Haining and Estiu, Guillermina and Stahelin, Robert V and Rizk, Shahir S and Njimoh, Dieudonne L and Ryan, Yana and Chotivanich, Kesinee and Nguon, Chea and Ghorbal, Mehdi and Lopez-Rubio, Jose-Juan and Pfrender, Michael and Emrich, Scott and Mohandas, Narla and Dondorp, Arjen M and Wiest, Olaf and Haldar, Kasturi
Nature (London), ISSN 0028-0836, 04/2015, Volume 520, Issue 7549, pp. 683 - 687
Science & Technology - Other Topics | Multidisciplinary Sciences | Science & Technology | Plasmodium falciparum - enzymology | Malaria, Falciparum - drug therapy | Genome-Wide Association Study | Phosphatidylinositol Phosphates - metabolism | Phosphatidylinositol 3-Kinase - antagonists & inhibitors | Protozoan Proteins - antagonists & inhibitors | Models, Molecular | Drug Resistance - drug effects | Plasmodium falciparum - drug effects | Protozoan Proteins - genetics | Antimalarials - pharmacology | Phosphatidylinositol 3-Kinase - chemistry | Drug Resistance - genetics | Malaria, Falciparum - parasitology | Artemisinins - pharmacology | Protozoan Proteins - metabolism | Mutation | Phosphatidylinositol 3-Kinase - metabolism | Malaria | Lipids | Parasites | Kinases | Drug resistance | DNA repair | Binding sites | Crystal structure | Index Medicus | Life Sciences | Cellular Biology | Subcellular Processes
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3. Full Text Alzheimer’s Disease Risk Genes and Mechanisms of Disease Pathogenesis
by Karch, Celeste M and Goate, Alison M
Biological psychiatry (1969), ISSN 0006-3223, 2015, Volume 77, Issue 1, pp. 43 - 51
Psychiatry | Amyloid Precursor Protein | Endocytosis | Alzheimer’s Disease | Cholesterol Metabolism | Immune Response | Genome-Wide Association Studies | Alzheimers Disease | Neurosciences | Neurosciences & Neurology | Life Sciences & Biomedicine | Science & Technology | Genetic Predisposition to Disease | Genome-Wide Association Study | Humans | Risk Factors | Presenilin-1 - genetics | Cholesterol - metabolism | Phenotype | Amyloid beta-Protein Precursor - genetics | Presenilin-2 - genetics | Alzheimer Disease - metabolism | Alzheimer Disease - genetics | Alzheimer Disease - immunology | Genetic research | Alzheimer's disease | Genes | Genomics | Risk factors | Genetic polymorphisms | Index Medicus | endocytosis | amyloid precursor protein | immune response | genome wide association studies | cholesterol metabolism
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4. Full Text Elucidating Compound Mechanism of Action by Network Perturbation Analysis
by Woo, Jung Hoon and Shimoni, Yishai and Yang, Wan Seok and Subramaniam, Prem and Iyer, Archana and Nicoletti, Paola and Rodríguez Martínez, María and López, Gonzalo and Mattioli, Michela and Realubit, Ronald and Karan, Charles and Stockwell, Brent R and Bansal, Mukesh and Califano, Andrea
Cell (Cambridge), ISSN 0092-8674, 07/2015, Volume 162, Issue 2, pp. 441 - 451
Biochemistry & Molecular Biology | Life Sciences & Biomedicine | Science & Technology | Cell Biology | Genome-Wide Association Study | Algorithms | Epistasis, Genetic | Small Molecule Libraries | Antineoplastic Agents - pharmacology | Antineoplastic Agents - chemistry | Molecular Targeted Therapy | Neoplasms - drug therapy | Proteins | Analysis | Genomics | Protein binding | Index Medicus
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5. Full Text Mechanisms of change in gene copy number
by Rosenberg, Susan M and Hastings, P. J and Lupski, James R and Ira, Grzegorz
Nature reviews. Genetics, ISSN 1471-0056, 08/2009, Volume 10, Issue 8, pp. 551 - 564
Life Sciences & Biomedicine | Genetics & Heredity | Science & Technology | Fundamental and applied biological sciences. Psychology | Biological and medical sciences | Molecular and cellular biology | Genetics of eukaryotes. Biological and molecular evolution | Molecular genetics | Genes. Genome | Genome-Wide Association Study | Gene Dosage | Models, Genetic | Recombination, Genetic | Humans | DNA replication | Research | Gene mutations | DNA repair | Health aspects | Index Medicus
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