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The Journal of Cell Biology, ISSN 0021-9525, 8/2009, Volume 186, Issue 4, pp. 571 - 587
Invadopodia are matrix-degrading membrane protrusions in invasive carcinoma cells. The mechanisms regulating invadopodium assembly and maturation are not... 
Phosphorylation | Quantification | Cell lines | Actin depolymerizing factors | Actins | Polymerization | Small interfering RNA | Antibodies | Protein precursors | Physiological regulation | CARCINOMA-CELLS | TYROSINE PHOSPHORYLATION | EGF | PATHWAY | ACTIN POLYMERIZATION | IN-VIVO | CANCER-CELL INVASION | EXTRACELLULAR-MATRIX DEGRADATION | ARP2/3 COMPLEX | PODOSOME FORMATION | CELL BIOLOGY | Oncogene Proteins - genetics | RNA, Small Interfering - genetics | Oncogene Protein pp60(v-src) - metabolism | Actin Depolymerizing Factors - genetics | Humans | Actins - metabolism | Extracellular Matrix - metabolism | Actin-Related Protein 2-3 Complex - genetics | Recombinant Fusion Proteins - metabolism | Actin Depolymerizing Factors - metabolism | Actin-Related Protein 2-3 Complex - metabolism | Wiskott-Aldrich Syndrome Protein, Neuronal - metabolism | Protein Structure, Tertiary | Neoplasm Invasiveness | Oncogene Proteins - metabolism | Rats | Epidermal Growth Factor - metabolism | Oncogene Protein pp60(v-src) - genetics | Cortactin - metabolism | Matrix Metalloproteinase 14 - metabolism | Mammary Neoplasms, Animal - pathology | Tyrosine - metabolism | Animals | Cortactin - genetics | Mammary Neoplasms, Animal - metabolism | Adaptor Proteins, Signal Transducing - genetics | Matrix Metalloproteinase 14 - genetics | Cell Line, Tumor | Recombinant Fusion Proteins - genetics | Adaptor Proteins, Signal Transducing - metabolism | Wiskott-Aldrich Syndrome Protein, Neuronal - genetics | RNA, Small Interfering - metabolism | Metastasis | Properties | Observations | Actin | Cancer cells | Membrane proteins
Journal Article
Journal Article
Journal of Biological Chemistry, ISSN 0021-9258, 02/2013, Volume 288, Issue 6, pp. 4241 - 4250
Journal Article
Journal of Cell Biology, ISSN 0021-9525, 11/2017, Volume 216, Issue 11, pp. 3745 - 3765
The conditional use of actin during clathrin-mediated endocytosis in mammalian cells suggests that the cell controls whether and how actin is used. Using a... 
RECRUITMENT | ENDOSOMES | SELECTIVE INHIBITOR | LOWE | BAR PROTEINS | CYTOSKELETON | MEDIATED ENDOCYTOSIS | DYNAMIN | OCRL | MULTIPLE | CELL BIOLOGY | Oculocerebrorenal Syndrome - genetics | Retinal Pigment Epithelium - metabolism | Sorting Nexins - genetics | Phosphatidylinositol Phosphates - metabolism | Cytoskeletal Proteins - genetics | Humans | Protein Multimerization | Actins - metabolism | Actin-Related Protein 2-3 Complex - genetics | cdc42 GTP-Binding Protein - metabolism | Intracellular Signaling Peptides and Proteins - metabolism | Clathrin-Coated Vesicles - metabolism | Phosphatidylinositol 4,5-Diphosphate - metabolism | Actin-Related Protein 2-3 Complex - metabolism | Endocytosis | Transfection | RNA Interference | Time Factors | Cytoskeletal Proteins - metabolism | Phosphatidylinositols - metabolism | Sorting Nexins - metabolism | Wiskott-Aldrich Syndrome Protein, Neuronal - metabolism | Intracellular Signaling Peptides and Proteins - genetics | Coated Pits, Cell-Membrane - metabolism | Phosphoric Monoester Hydrolases - genetics | Signal Transduction | Xenopus laevis | Clathrin - metabolism | Hydrolysis | Animals | cdc42 GTP-Binding Protein - genetics | CRISPR-Cas Systems | Oculocerebrorenal Syndrome - metabolism | HeLa Cells | Phosphoric Monoester Hydrolases - metabolism | Wiskott-Aldrich Syndrome Protein, Neuronal - genetics | Biological Sciences | Naturvetenskap | Natural Sciences | Cellbiologi | Biologiska vetenskaper | Cell Biology
Journal Article
PLoS ONE, ISSN 1932-6203, 09/2013, Volume 8, Issue 9, p. e75436
Journal Article
Journal Article
PLoS ONE, ISSN 1932-6203, 12/2015, Volume 10, Issue 12, p. e0143993
MicroRNAs (miRNAs, micro ribonucleic acids) are pivotal post-transcriptional regulators of gene expression. These endogenous small non-coding RNAs play... 
EPITHELIAL-MESENCHYMAL TRANSITION | HEPATOCELLULAR-CARCINOMA | PLASMINOGEN-ACTIVATOR | MULTIDISCIPLINARY SCIENCES | JUNCTIONAL ADHESION MOLECULE | ESTROGEN-RECEPTOR-ALPHA | ALPHA-V-BETA-3 INTEGRIN | INVADOPODIUM FORMATION | N-WASP | TUMOR-CELLS | ACTIN CYTOSKELETON | Integrin alphaV - chemistry | Cell Proliferation | Humans | Actins - metabolism | MicroRNAs - metabolism | MCF-7 Cells | RNA Interference | Wiskott-Aldrich Syndrome Protein, Neuronal - antagonists & inhibitors | Base Sequence | Female | Wiskott-Aldrich Syndrome Protein, Neuronal - metabolism | 3' Untranslated Regions | Integrin alphaV - genetics | Integrin alphaV - metabolism | Down-Regulation | Cell Size | Sequence Alignment | Breast Neoplasms - genetics | Breast Neoplasms - pathology | Cell Line, Tumor | Cytoskeleton - metabolism | MicroRNAs - genetics | MicroRNAs - chemistry | Wiskott-Aldrich Syndrome Protein, Neuronal - genetics | Cell Movement | RNA, Small Interfering - metabolism | MicroRNA | Breast cancer | Genetic aspects | Cytoskeletal proteins | Genetic regulation | Health aspects | Integrins | Atomic force microscopy | Post-transcription | Regulators | Target recognition | Motility | Cytology | Biochemistry | Confocal | Kinases | Cell morphology | Cell adhesion & migration | Interleukin 6 | KLF4 protein | Actin | Tumorigenesis | Growth factors | Wiskott-Aldrich syndrome | Invasiveness | Gynecology | Cortex | MiRNA | Rac1 protein | siRNA | Gene expression | Obstetrics | Ribonucleic acids | Microscopy | MicroRNAs | Cell lines | Breast | Cytoskeleton | Cell size | Immunofluorescence | Cancer
Journal Article
Journal of Cell Biology, ISSN 0021-9525, 10/2012, Volume 199, Issue 3, pp. 527 - 544
Metastasizing tumor cells use matrix metalloproteases, such as the transmembrane collagenase MT1-MMP, together with actin-based protrusions, to break through... 
CARCINOMA-CELLS | PERICELLULAR PROTEOLYSIS | CANCER INVASION | CORTACTIN | DYNAMICS | INVADOPODIUM FORMATION | MEMBRANE-TYPE-1 MATRIX-METALLOPROTEINASE | EXTRACELLULAR-MATRIX | TUMOR-CELLS | E-CADHERIN | CELL BIOLOGY | RNA, Small Interfering - genetics | Adenocarcinoma - pathology | Humans | Protein Multimerization | Actins - metabolism | Carcinoma, Intraductal, Noninfiltrating - metabolism | Extracellular Matrix - metabolism | Pseudopodia - pathology | Breast - metabolism | Cell Movement - physiology | Immunoenzyme Techniques | Breast Neoplasms - metabolism | Adenocarcinoma - metabolism | Wiskott-Aldrich Syndrome Protein, Neuronal - antagonists & inhibitors | Fluorescence Resonance Energy Transfer | Carcinoma, Ductal, Breast - pathology | Female | Cell Membrane - metabolism | Tumor Cells, Cultured | Wiskott-Aldrich Syndrome Protein, Neuronal - metabolism | Carcinoma, Ductal, Breast - metabolism | Actin Cytoskeleton - metabolism | Neoplasm Invasiveness | RNA, Messenger - genetics | Matrix Metalloproteinase 14 - metabolism | Blotting, Western | Protein Transport | Animals | Carcinoma, Intraductal, Noninfiltrating - pathology | Pseudopodia - metabolism | Breast Neoplasms - pathology | Fluorescent Antibody Technique | Mice | Wiskott-Aldrich Syndrome Protein, Neuronal - genetics | Physiological aspects | Pseudopodia | Actin | Health aspects | Tumors
Journal Article