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Nature, ISSN 0028-0836, 03/2012, Volume 483, Issue 7389, pp. 336 - 340
Journal Article
The Journal of Cell Biology, ISSN 0021-9525, 8/2009, Volume 186, Issue 4, pp. 571 - 587
Invadopodia are matrix-degrading membrane protrusions in invasive carcinoma cells. The mechanisms regulating invadopodium assembly and maturation are not... 
Phosphorylation | Quantification | Cell lines | Actin depolymerizing factors | Actins | Polymerization | Small interfering RNA | Antibodies | Protein precursors | Physiological regulation | CARCINOMA-CELLS | TYROSINE PHOSPHORYLATION | EGF | PATHWAY | ACTIN POLYMERIZATION | IN-VIVO | CANCER-CELL INVASION | EXTRACELLULAR-MATRIX DEGRADATION | ARP2/3 COMPLEX | PODOSOME FORMATION | CELL BIOLOGY | Oncogene Proteins - genetics | RNA, Small Interfering - genetics | Oncogene Protein pp60(v-src) - metabolism | Actin Depolymerizing Factors - genetics | Humans | Actins - metabolism | Extracellular Matrix - metabolism | Actin-Related Protein 2-3 Complex - genetics | Recombinant Fusion Proteins - metabolism | Actin Depolymerizing Factors - metabolism | Actin-Related Protein 2-3 Complex - metabolism | Wiskott-Aldrich Syndrome Protein, Neuronal - metabolism | Protein Structure, Tertiary | Neoplasm Invasiveness | Oncogene Proteins - metabolism | Rats | Epidermal Growth Factor - metabolism | Oncogene Protein pp60(v-src) - genetics | Cortactin - metabolism | Matrix Metalloproteinase 14 - metabolism | Mammary Neoplasms, Animal - pathology | Tyrosine - metabolism | Animals | Cortactin - genetics | Mammary Neoplasms, Animal - metabolism | Adaptor Proteins, Signal Transducing - genetics | Matrix Metalloproteinase 14 - genetics | Cell Line, Tumor | Recombinant Fusion Proteins - genetics | Adaptor Proteins, Signal Transducing - metabolism | Wiskott-Aldrich Syndrome Protein, Neuronal - genetics | RNA, Small Interfering - metabolism | Metastasis | Properties | Observations | Actin | Cancer cells | Membrane proteins | Cell growth | Biochemistry | Cells | Cell cycle | Cancer | Index Medicus
Journal Article
Journal of Cell Biology, ISSN 0021-9525, 10/2012, Volume 199, Issue 3, pp. 527 - 544
Metastasizing tumor cells use matrix metalloproteases, such as the transmembrane collagenase MT1-MMP, together with actin-based protrusions, to break through... 
CARCINOMA-CELLS | PERICELLULAR PROTEOLYSIS | CANCER INVASION | CORTACTIN | DYNAMICS | INVADOPODIUM FORMATION | MEMBRANE-TYPE-1 MATRIX-METALLOPROTEINASE | EXTRACELLULAR-MATRIX | TUMOR-CELLS | E-CADHERIN | CELL BIOLOGY | RNA, Small Interfering - genetics | Adenocarcinoma - pathology | Humans | Protein Multimerization | Actins - metabolism | Carcinoma, Intraductal, Noninfiltrating - metabolism | Extracellular Matrix - metabolism | Pseudopodia - pathology | Breast - metabolism | Cell Movement - physiology | Immunoenzyme Techniques | Breast Neoplasms - metabolism | Adenocarcinoma - metabolism | Wiskott-Aldrich Syndrome Protein, Neuronal - antagonists & inhibitors | Fluorescence Resonance Energy Transfer | Carcinoma, Ductal, Breast - pathology | Female | Cell Membrane - metabolism | Tumor Cells, Cultured | Wiskott-Aldrich Syndrome Protein, Neuronal - metabolism | Carcinoma, Ductal, Breast - metabolism | Actin Cytoskeleton - metabolism | Neoplasm Invasiveness | RNA, Messenger - genetics | Matrix Metalloproteinase 14 - metabolism | Blotting, Western | Protein Transport | Animals | Carcinoma, Intraductal, Noninfiltrating - pathology | Pseudopodia - metabolism | Breast Neoplasms - pathology | Fluorescent Antibody Technique | Mice | Wiskott-Aldrich Syndrome Protein, Neuronal - genetics | Physiological aspects | Pseudopodia | Actin | Health aspects | Tumors | Proteins | Eukaryotes | Membranes | Matrix | Cellular biology | Cytoskeleton | Index Medicus
Journal Article
Journal of Clinical Investigation, ISSN 0021-9738, 04/2013, Volume 123, Issue 4, pp. 1501 - 1512
Mycolactone is a diffusible lipid secreted by the human pathogen Mycobacterium ulcerans, which induces the formation of open skin lesions referred to as Buruli... 
CDC42 | MEDICINE, RESEARCH & EXPERIMENTAL | COMPLEX | CYTOKINE PRODUCTION | INHIBITION | ACTIN POLYMERIZATION | TOXIN | COLOCALIZATION | MYCOBACTERIUM-ULCERANS | N-WASP | GTPASE-BINDING | Humans | Protein Multimerization | Actins - metabolism | Molecular Sequence Data | Actin-Related Protein 2-3 Complex - metabolism | Mycobacterium ulcerans | Cell Nucleus - metabolism | Buruli Ulcer - microbiology | Wiskott-Aldrich Syndrome Protein, Neuronal - antagonists & inhibitors | Actins - chemistry | Macrolides - pharmacology | Buruli Ulcer - pathology | Wiskott-Aldrich Syndrome Protein, Neuronal - metabolism | Amino Acid Sequence | Epidermis - pathology | Actin Cytoskeleton - metabolism | Wiskott-Aldrich Syndrome Protein Family - metabolism | Epidermis - drug effects | Mice, Inbred C57BL | Wiskott-Aldrich Syndrome Protein Family - antagonists & inhibitors | Cell Adhesion | Protein Transport | Animals | Keratinocytes - drug effects | Bacterial Toxins - pharmacology | Keratinocytes - metabolism | Mice | HeLa Cells | Carbazoles - pharmacology | Propanolamines - pharmacology | Buruli Ulcer - metabolism | Cell Movement | Wiskott-Aldrich syndrome | Physiological aspects | Development and progression | Buruli ulcer | Health aspects | Mycotoxins | Index Medicus | Abridged Index Medicus | Cellular Biology | Life Sciences | Bacterial Toxins | Wiskott-Aldrich Syndrome Protein Family | Actin Cytoskeleton | Wiskott-Aldrich Syndrome Protein, Neuronal | Macrolides | Keratinocytes | Actins | Epidermis | Actin-Related Protein 2-3 Complex | Carbazoles | Buruli Ulcer | Cell Nucleus | Propanolamines
Journal Article
eLife, ISSN 2050-084X, 2014, Volume 3
Clustering of proteins into micrometer-sized structures at membranes is observed in many signaling pathways. Most models of clustering are specific to... 
polymerization | phase separation | cell biology | actin regulation | signal transduction | structural biology | membrane clustering | biophysics | human | multivalency | WASP FAMILY | TYROSINE PHOSPHORYLATION | ACTIN POLYMERIZATION | Polymerization | NCK ADAPTER PROTEINS | CELL-SURFACE | ARP2/3 COMPLEX | PLASMA-MEMBRANE | Signal transduction | Multivalency | QUANTITATIVE FLUORESCENCE MICROSCOPY | Phase separation | Membrane clustering | Membrane organization | BIOLOGY | Actin regulation | T-CELLS | GPI-ANCHORED PROTEINS | Adaptor Proteins, Signal Transducing - chemistry | Amino Acid Sequence | Oncogene Proteins - chemistry | Actins - metabolism | Oncogene Proteins - metabolism | Molecular Sequence Data | Rats | Receptors, Cell Surface - metabolism | Wiskott-Aldrich Syndrome Protein, Neuronal - chemistry | Phase Transition | Amino Acid Motifs | Actin-Related Protein 2-3 Complex - metabolism | Animals | Peptides - metabolism | Membrane Proteins - chemistry | Protein Binding | Cell Membrane - metabolism | Membrane Proteins - metabolism | Lipid Bilayers - metabolism | Wiskott-Aldrich Syndrome Protein, Neuronal - metabolism | Adaptor Proteins, Signal Transducing - metabolism | Cluster Analysis | Adaptor proteins | Studies | Proteins | Medical research | Hypotheses | Filaments | Actin | Lipids | Phase transitions | Lipid bilayers | Index Medicus
Journal Article
Journal of Biological Chemistry, ISSN 0021-9258, 02/2013, Volume 288, Issue 6, pp. 4241 - 4250
Journal Article
Journal Article
Journal of Cell Biology, ISSN 0021-9525, 11/2017, Volume 216, Issue 11, pp. 3745 - 3765
The conditional use of actin during clathrin-mediated endocytosis in mammalian cells suggests that the cell controls whether and how actin is used. Using a... 
RECRUITMENT | ENDOSOMES | SELECTIVE INHIBITOR | LOWE | BAR PROTEINS | CYTOSKELETON | MEDIATED ENDOCYTOSIS | DYNAMIN | OCRL | MULTIPLE | CELL BIOLOGY | Oculocerebrorenal Syndrome - genetics | Retinal Pigment Epithelium - metabolism | Sorting Nexins - genetics | Phosphatidylinositol Phosphates - metabolism | Cytoskeletal Proteins - genetics | Humans | Protein Multimerization | Actins - metabolism | Actin-Related Protein 2-3 Complex - genetics | cdc42 GTP-Binding Protein - metabolism | Intracellular Signaling Peptides and Proteins - metabolism | Clathrin-Coated Vesicles - metabolism | Phosphatidylinositol 4,5-Diphosphate - metabolism | Actin-Related Protein 2-3 Complex - metabolism | Endocytosis | Transfection | RNA Interference | Time Factors | Cytoskeletal Proteins - metabolism | Phosphatidylinositols - metabolism | Sorting Nexins - metabolism | Wiskott-Aldrich Syndrome Protein, Neuronal - metabolism | Intracellular Signaling Peptides and Proteins - genetics | Coated Pits, Cell-Membrane - metabolism | Phosphoric Monoester Hydrolases - genetics | Signal Transduction | Xenopus laevis | Clathrin - metabolism | Hydrolysis | Animals | cdc42 GTP-Binding Protein - genetics | CRISPR-Cas Systems | Oculocerebrorenal Syndrome - metabolism | HeLa Cells | Phosphoric Monoester Hydrolases - metabolism | Wiskott-Aldrich Syndrome Protein, Neuronal - genetics | Coated pits | Cdc42 protein | Comets | Cell culture | Clathrin | Phosphoinositides | Guanosine | Polymerization | Biochemistry | Mammals | Cells | Polyimide resins | Mammalian cells | Signaling | Actin | Cytoskeleton | Curvature | Index Medicus | Biological Sciences | Naturvetenskap | Natural Sciences | Cellbiologi | Biologiska vetenskaper | Cell Biology
Journal Article
PLoS ONE, ISSN 1932-6203, 09/2013, Volume 8, Issue 9, pp. e75436 - e75436
Journal Article