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The Journal of biological chemistry, ISSN 1083-351X, 2018, Volume 293, Issue 21, pp. 7942 - 7968
In aortic vascular smooth muscle (VSM), the canonical Wnt receptor LRP6 inhibits protein arginine (Arg... 
atherosclerosis | Type 2 diabetes | BONE BIOLOGY | cardiovascular disease | TRANSCRIPTION FACTOR RUNX2 | SINGLETON-MERTEN SYNDROME | CARDIOVASCULAR CALCIFICATION | BIOCHEMISTRY & MOLECULAR BIOLOGY | INHIBITS VASCULAR CALCIFICATION | vascular biology | metabolic syndrome | DIABETES-MELLITUS | Wnt signaling | arteriosclerosis | protein methylation | ATHEROSCLEROTIC CALCIFICATION | IN-VIVO | calcification | ARGININE METHYLATION | vascular smooth muscle cells | CORONARY-ARTERY-DISEASE | Calcinosis - genetics | RNA Helicases - metabolism | Poly-ADP-Ribose Binding Proteins - metabolism | Calcium - metabolism | Humans | Myocytes, Smooth Muscle - pathology | Antiviral Agents - metabolism | Aorta - metabolism | Arteriosclerosis - genetics | Wnt Proteins - metabolism | Wnt Proteins - genetics | RNA Helicases - genetics | Calcinosis - metabolism | RNA Recognition Motif Proteins - metabolism | DNA Helicases - genetics | Myocytes, Smooth Muscle - metabolism | Low Density Lipoprotein Receptor-Related Protein-6 | Signal Transduction | Mice, Inbred C57BL | Cells, Cultured | Poly-ADP-Ribose Binding Proteins - genetics | beta Catenin - metabolism | beta Catenin - genetics | Mice, Knockout | Aorta - pathology | DNA Helicases - metabolism | Adaptor Proteins, Signal Transducing - physiology | Animals | Arteriosclerosis - metabolism | Mice | RNA Recognition Motif Proteins - genetics | Receptors, LDL - physiology | Calcinosis - pathology | Arteriosclerosis - pathology | Molecular Bases of Disease
Journal Article
The Journal of cell biology, ISSN 1540-8140, 2012, Volume 197, Issue 2, pp. 313 - 325
Centriole-to–basal body conversion, a complex process essential for ciliogenesis, involves the progressive addition of specific proteins to centrioles. CHIBBY (CBY... 
PROTEIN | CENTRIOLE | COMPARATIVE GENOMICS | JOHNSTONS ORGAN | CATENIN | DIFFERENTIATION | SENSORY CILIA | INTRAFLAGELLAR TRANSPORT | HEARING | REGULATORY FACTOR-X | CELL BIOLOGY | Molecular Sequence Data | Male | Wnt1 Protein - metabolism | Spermatozoa - metabolism | Drosophila Proteins - metabolism | Drosophila Proteins - biosynthesis | DNA-Binding Proteins - metabolism | Drosophila melanogaster - metabolism | Nuclear Proteins - biosynthesis | Infertility, Male | Carrier Proteins - chemistry | Sensory Receptor Cells - metabolism | Nuclear Proteins - genetics | Wnt Signaling Pathway | Amino Acid Sequence | Carrier Proteins - biosynthesis | Cells, Cultured | Nuclear Proteins - metabolism | Drosophila Proteins - chemistry | Nuclear Proteins - chemistry | Regulatory Factor X Transcription Factors | Cilia - metabolism | Protein Transport | Transcription Factors - metabolism | Carrier Proteins - genetics | Animals | Carrier Proteins - metabolism | Mice | Centrioles - metabolism | Drosophila Proteins - genetics | Proteins | Animal genetics | Drosophila | Physiological aspects | Genetic aspects | Research | Gene expression | Wnt1 Protein | Drosophila Proteins | Spermatozoa | Biochemistry, Molecular Biology | Nuclear Proteins | Sensory Receptor Cells | Life Sciences | Transcription Factors | Centrioles | Drosophila melanogaster | Carrier Proteins | Cilia | DNA-Binding Proteins
Journal Article
PloS one, ISSN 1932-6203, 2011, Volume 6, Issue 10, p. e25519
Background: Ankrd2 (also known as Arpp) together with Ankrd1/CARP and DARP are members of the MARP mechanosensing proteins that form a complex with titin (N2A... 
SKELETAL-MUSCLE | CARP | PDZ DOMAINS | MULTIDISCIPLINARY SCIENCES | GENE-EXPRESSION | ANKYRIN-REPEAT PROTEIN | NUCLEAR-PROTEIN | TIGHT JUNCTION | CELL | BINDING | FAMILY | Homeodomain Proteins - metabolism | Humans | Transcriptome | Muscle Proteins - deficiency | Muscle Fibers, Skeletal - metabolism | Promoter Regions, Genetic - genetics | RNA Interference | Repressor Proteins - deficiency | Nuclear Proteins - deficiency | Muscle Proteins - metabolism | Transcription, Genetic | Nuclear Proteins - genetics | Muscle, Striated - cytology | Repressor Proteins - metabolism | Cell Line | Tumor Suppressor Protein p53 - metabolism | Repressor Proteins - genetics | Nuclear Proteins - metabolism | MyoD Protein - metabolism | src Homology Domains | Muscle Proteins - genetics | Transcription Factors - metabolism | Homeobox Protein Nkx-2.5 | Mechanotransduction, Cellular | Animals | PDZ Domains | Muscle Fibers, Skeletal - cytology | Muscle, Striated - metabolism | Actin | Genes | Calpain | Bone morphogenetic proteins | Cellular signal transduction | DNA binding proteins | Genetic transcription | Transforming growth factors | Tumor proteins | Muscle proteins | Protein binding | Heart | Biotechnology | Transcription factors | Intercellular signalling | Connectin | Wnt protein | Calcium | Cardiomyopathy | p53 Protein | Homeostasis | Intracellular signalling | Feedback loops | Nuclei | Proteins | Signal transduction | Endocytosis | Pathways | Methyl-CpG binding protein | Rodents | DNA methylation | Localization | Nkx2.5 protein | Deoxyribonucleic acid--DNA | MyoD protein | Myotubes | Calcium (intracellular) | Carp | MAP kinase | Cardiomyocytes | Gene expression | Insulin | Skeletal muscle | Myoblasts | Pax6 protein | Musculoskeletal system | MeCP2 protein | Cytoskeleton | Genetic engineering | Mutation | Molecular biology | Cytoplasm | Apoptosis | Deoxyribonucleic acid | DNA
Journal Article
The EMBO Journal, ISSN 1460-2075, 2009, Volume 29, Issue 1, pp. 41 - 54
Journal Article
Science (American Association for the Advancement of Science), ISSN 1095-9203, 2012, Volume 337, Issue 6090, pp. 59 - 64
Journal Article
eLife, ISSN 2050-084X, 2013, Volume 2, p. e01340
The Hedgehog (Hh) signal is transduced across the membrane by the heptahelical protein Smoothened (Smo... 
oxysterol | Hedgehog signaling | Zebrafish | cysteine rich domain | smoothened | MAXIMUM-LIKELIHOOD | STEM-CELLS | PROTEIN | SONIC HEDGEHOG | CYSTEINE-RICH DOMAINS | CRYSTAL-STRUCTURE | PATHWAY ACTIVITY | BIOLOGY | N-TERMINAL DOMAIN | MAMMALIAN-CELLS | PRIMARY CILIUM | Hedgehog Proteins - chemistry | Receptors, G-Protein-Coupled - metabolism | Hedgehog Proteins - metabolism | Crystallography, X-Ray | Structure-Activity Relationship | Hedgehog Proteins - genetics | Gene Expression Regulation, Developmental | Smoothened Receptor | Escherichia coli - metabolism | Binding Sites | Protein Structure, Tertiary | Recombinant Proteins - metabolism | Protein Structure, Secondary | Signal Transduction | Zebrafish Proteins - chemistry | Sterols - chemistry | Zebrafish Proteins - metabolism | Zebrafish Proteins - antagonists & inhibitors | Models, Molecular | Recombinant Proteins - chemistry | Recombinant Proteins - genetics | Zebrafish - growth & development | Zebrafish - genetics | Animals | Escherichia coli - genetics | Zebrafish - metabolism | Embryo, Nonmammalian | Receptors, G-Protein-Coupled - antagonists & inhibitors | Protein Binding | Ligands | Mice | Receptors, G-Protein-Coupled - genetics | Zebrafish Proteins - genetics | Receptors, G-Protein-Coupled - chemistry | Wnt protein | Frizzled protein | Genes | Lipids | Biology | Hydrophobicity | Chromatography | Membrane proteins | Medicine | Proteins | Hedgehog protein | Binding sites | Crystal structure | Structure-function relationships
Journal Article
PLoS genetics, ISSN 1553-7404, 2018, Volume 14, Issue 4, p. e1007339
Wnt signaling provides a paradigm for cell-cell signals that regulate embryonic development and stem cell homeostasis and are inappropriately activated in... 
DISHEVELLED PROTEIN | PATHWAY ACTIVATION | AXIN | ADENOMATOUS POLYPOSIS-COLI | TUMOR-SUPPRESSOR APC | OVERLAPPING ROLES | DEP DOMAIN | NEGATIVE REGULATION | GENETICS & HEREDITY | DROSOPHILA APC2 | DIX DOMAIN | Wnt1 Protein - genetics | Drosophila melanogaster - embryology | Transcription Factors - chemistry | Axin Protein - genetics | Axin Protein - chemistry | Multiprotein Complexes - genetics | Wnt1 Protein - metabolism | Armadillo Domain Proteins - genetics | Drosophila Proteins - metabolism | RNA, Messenger - metabolism | Drosophila melanogaster - genetics | Recombinant Fusion Proteins - metabolism | Axin Protein - metabolism | Apc1 Subunit, Anaphase-Promoting Complex-Cyclosome - metabolism | Drosophila melanogaster - metabolism | Multiprotein Complexes - metabolism | Proteolysis | Tumor Suppressor Proteins - chemistry | Tumor Suppressor Proteins - genetics | Transcription, Genetic | Wnt Signaling Pathway | Axin Signaling Complex - chemistry | Cell Line | Tumor Suppressor Proteins - metabolism | Animals, Genetically Modified | RNA, Messenger - genetics | Apc1 Subunit, Anaphase-Promoting Complex-Cyclosome - genetics | Armadillo Domain Proteins - chemistry | Drosophila Proteins - chemistry | Recombinant Fusion Proteins - chemistry | Transcription Factors - genetics | Glycogen Synthase Kinase 3 - metabolism | Apc1 Subunit, Anaphase-Promoting Complex-Cyclosome - chemistry | Transcription Factors - metabolism | Multiprotein Complexes - chemistry | Animals | Axin Signaling Complex - metabolism | Glycogen Synthase Kinase 3 - genetics | Axin Signaling Complex - genetics | Armadillo Domain Proteins - metabolism | Recombinant Fusion Proteins - genetics | Drosophila Proteins - genetics | Binding proteins | Wnt proteins | Health aspects | Stoichiometry | Phosphorylation | Wnt protein | Funding | Glycogen synthase | Genes | Homeostasis | Kinases | Proteins | β-catenin | Embryogenesis | Ubiquitination | Localization | Dishevelled protein | Glycogen | Polymerization | Curricula | Embryos | Adenomatous polyposis coli | Microscopy | Insects | Stem cells | Regulation | Genetic engineering | Molecular biology | Cancer
Journal Article
PLoS biology, ISSN 1545-7885, 2006, Volume 4, Issue 6, pp. e187 - 1009
The genes encoding members of the wingless-related MMTV integration site ( WNT) and fibroblast growth factor ( FGF) families coordinate growth, morphogenesis,... 
DETERMINING REGION | NUCLEAR IMPORT | SERTOLI-CELL DIFFERENTIATION | TESTIS DIFFERENTIATION | FACTOR SOX9 | DEVELOPING GONAD | GERM-CELLS | BIOCHEMISTRY & MOLECULAR BIOLOGY | MOUSE | BIOLOGY | EXPRESSION | CHONDROCYTE DIFFERENTIATION | Gonads - embryology | Sex-Determining Region Y Protein - genetics | Fibroblast Growth Factor 9 - physiology | Male | Wnt Proteins - metabolism | Fibroblast Growth Factor 9 - genetics | Gonads - cytology | Sex Determination Processes | Wnt Proteins - genetics | Gene Expression Regulation, Developmental | Female | Proto-Oncogene Proteins - metabolism | High Mobility Group Proteins - metabolism | Signal Transduction | Proto-Oncogene Proteins - genetics | Transcription Factors - genetics | Fibroblast Growth Factor 9 - metabolism | Transcription Factors - metabolism | Gonads - metabolism | Animals | Proto-Oncogene Proteins - physiology | Sex-Determining Region Y Protein - metabolism | Mice | Wnt Proteins - physiology | Mutation | SOX9 Transcription Factor | Wnt4 Protein | High Mobility Group Proteins - genetics | Cell culture | Experiments | Insulin | Embryos | Rodents | Genes | High Mobility Group Proteins | Sex-Determining Region Y Protein | Biochemistry, Molecular Biology | Wnt Proteins | Life Sciences | Transcription Factors | Proto-Oncogene Proteins | Gonads | Fibroblast Growth Factor 9 | Development | Mus (Mouse) | Vertebrates | Mammals | Cell Biology
Journal Article