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Nature Methods, ISSN 1548-7091, 03/2013, Volume 10, Issue 3, pp. 249 - 252
We report an optogenetic method based on Arabidopsis thaliana cryptochrome 2 for rapid and reversible protein oligomerization in response to blue light. We... 
SYSTEM | SPATIOTEMPORAL CONTROL | LIGHT | BIOLOGY | BIOCHEMICAL RESEARCH METHODS | INDUCTION | LIVING CELLS | Wnt3A Protein - metabolism | NIH 3T3 Cells | Cryptochromes - radiation effects | Fluorescence Recovery After Photobleaching | Humans | Cryptochromes - genetics | Cytoplasm - metabolism | rhoA GTP-Binding Protein - metabolism | beta Catenin - radiation effects | rhoA GTP-Binding Protein - genetics | Recombinant Fusion Proteins - metabolism | Arabidopsis Proteins - metabolism | Cell Nucleus - metabolism | Light Signal Transduction | Transfection | Luminescent Proteins - radiation effects | Cell Nucleus - radiation effects | Recombinant Fusion Proteins - radiation effects | Light | HEK293 Cells | Wnt3A Protein - radiation effects | Transcription, Genetic | rhoA GTP-Binding Protein - radiation effects | Cell Culture Techniques | Wnt Signaling Pathway - radiation effects | Cryptochromes - metabolism | Protein Multimerization - radiation effects | Arabidopsis Proteins - genetics | Cytoplasm - radiation effects | Wnt3A Protein - genetics | Enzyme-Linked Immunosorbent Assay | beta Catenin - metabolism | Blotting, Western | beta Catenin - genetics | Arabidopsis Proteins - radiation effects | Animals | Mice | Luminescent Proteins - metabolism | Arabidopsis thaliana | Plant genetics | Physiological aspects | Protein biosynthesis | Genetic aspects | Research | Genetic transcription | Biochemistry | Mammals | Photobiology | Protein synthesis
Journal Article
Journal Article
Nature Medicine, ISSN 1078-8956, 2012, Volume 18, Issue 4, pp. 572 - 579
Nat Med. 2012 Mar 4;18(4):572-9. doi: 10.1038/nm.2667. Macrophage-derived Wnt opposes Notch signaling to specify hepatic progenitor cell fate in chronic liver... 
MEDICINE, RESEARCH & EXPERIMENTAL | BIOCHEMISTRY & MOLECULAR BIOLOGY | HUMAN JAGGED1 | CELL BIOLOGY | ALAGILLE-SYNDROME | BILE-DUCT DEVELOPMENT | REGULATES FORMATION | MOUSE MODEL | CHOLINE-DEFICIENT | GENE-EXPRESSION | NUMB | OVAL CELLS | DIFFERENTIATION | Wnt3A Protein - metabolism | Ethionine - administration & dosage | Keratins, Hair-Specific - genetics | Receptors, Notch - metabolism | Humans | Middle Aged | Liver Diseases - pathology | Cell Communication - physiology | Male | RNA, Messenger - metabolism | Young Adult | Cell Differentiation - genetics | Intercellular Signaling Peptides and Proteins - metabolism | Liver Regeneration - genetics | Biliary Tract - metabolism | Serrate-Jagged Proteins | Adult | Antigens, Differentiation - metabolism | Female | Membrane Proteins - metabolism | Cell Differentiation - physiology | Hepatocytes - physiology | Jagged-1 Protein | Calcium-Binding Proteins - metabolism | Mice, Inbred C57BL | Cells, Cultured | Gene Expression Regulation - physiology | Mice, Transgenic | gamma-Glutamyltransferase - metabolism | Biliary Tract - physiopathology | Cell Communication - genetics | Liver Regeneration - physiology | beta Catenin - genetics | Biliary Tract - pathology | Nerve Tissue Proteins - metabolism | Macrophages - metabolism | Animals | Creatine Kinase - metabolism | Signal Transduction - physiology | Stem Cell Niche - physiology | Stem Cells - physiology | Aged | Mice | Chronic Disease | Liver diseases | Physiological aspects | Development and progression | Genetic aspects | Research | Macrophages | Cell differentiation | Wnt proteins | Signal transduction | Cellular biology | Gene expression
Journal Article
Neuron, ISSN 0896-6273, 02/2013, Volume 77, Issue 3, pp. 472 - 484
Major outputs of the neocortex are conveyed by corticothalamic axons (CTAs), which form reciprocal connections with thalamocortical axons, and... 
MUTANT MICE | CORTICAL AXONS | THALAMOCORTICAL AXONS | GROWTH | SEMAPHORIN 3E | CENTRAL-NERVOUS-SYSTEM | GUIDANCE | CHICK HINDLIMB | CAJAL-RETZIUS CELLS | NEUROSCIENCES | CEREBRAL-CORTEX | Thyroid Nuclear Factor 1 | Age Factors | Embryo, Mammalian | Leukocyte L1 Antigen Complex - metabolism | Gene Expression Regulation, Developmental - genetics | Axons - physiology | Cerebral Cortex - cytology | Neural Pathways - physiology | DNA-Binding Proteins - metabolism | POU Domain Factors - genetics | tau Proteins - genetics | Thalamus - physiology | Contactin 2 - metabolism | Repressor Proteins - metabolism | Glycoproteins - genetics | Tumor Suppressor Proteins - metabolism | Wnt3A Protein - genetics | Membrane Proteins - genetics | Mice, Inbred C57BL | Mice, Transgenic | Nuclear Proteins - metabolism | Transcription Factors - genetics | Nerve Tissue Proteins - genetics | Homeodomain Proteins - genetics | Membrane Glycoproteins - genetics | Nerve Tissue Proteins - metabolism | S100 Calcium Binding Protein G - metabolism | Transcription Factors - metabolism | Animals | Calbindin 2 | Thalamus - cytology | Cerebral Cortex - physiology | Luminescent Proteins - genetics | Mice | Body Patterning - genetics | Luminescent Proteins - metabolism | Developmental biology | Neurons | Studies | Laboratories | Experiments | Repressor Proteins | Cerebral Cortex | Cellular Biology | Neural Pathways | tau Proteins | Life Sciences | Contactin 2 | Gene Expression Regulation, Developmental | Body Patterning | Thalamus | Membrane Glycoproteins | Luminescent Proteins | DNA-Binding Proteins | POU Domain Factors | Calcium-Binding Protein, Vitamin D-Dependent | Glycoproteins | Nerve Tissue Proteins | Nuclear Proteins | Membrane Proteins | Axons | Homeodomain Proteins | Leukocyte L1 Antigen Complex | Transcription Factors | Wnt3A Protein | Tumor Suppressor Proteins | reciprocal connections | handshake | waiting period | PlexinD1 | axon guidance | Sema3E | thalamocortical | corticothalamic
Journal Article
The EMBO Journal, ISSN 0261-4189, 01/2010, Volume 29, Issue 1, pp. 41 - 54
Journal Article
Circulation Research, ISSN 0009-7330, 03/2009, Volume 104, Issue 6, pp. 733 - 741
Vascular calcification is a major risk factor for cardiovascular morbidity and mortality. To develop appropriate prevention and/or therapeutic strategies for... 
Vascular calcification | Smooth muscle cells | Genetic fate mapping | Lineage reprogramming | Runx2/Cbfa1 | WALL | CARDIAC & CARDIOVASCULAR SYSTEMS | vascular calcification | ATHEROSCLEROSIS | lineage reprogramming | genetic fate mapping | CARTILAGE | smooth muscle cells | IN-VITRO | DEFICIENT | CALCIFICATION | PERIPHERAL VASCULAR DISEASE | MICE | MUTATIONS | MATRIX-GLA-PROTEIN | HEMATOLOGY | EXPRESSION | Calcinosis - genetics | Vascular Diseases - pathology | Homeodomain Proteins - metabolism | Humans | Myocytes, Smooth Muscle - pathology | Extracellular Signal-Regulated MAP Kinases - metabolism | RNA, Messenger - metabolism | Stem Cells - metabolism | Wnt Proteins - metabolism | Core Binding Factor Alpha 1 Subunit - metabolism | Extracellular Signal-Regulated MAP Kinases - genetics | Arteries - metabolism | MAP Kinase Signaling System - genetics | Wnt Proteins - genetics | Mice, Mutant Strains | Bone Morphogenetic Protein 2 - metabolism | Calcinosis - metabolism | Myocytes, Smooth Muscle - metabolism | Chondrocytes - metabolism | SOX9 Transcription Factor - metabolism | Bone Morphogenetic Protein 2 - genetics | Chondrocytes - pathology | RNA, Messenger - genetics | Vascular Diseases - genetics | Arteries - pathology | Transcription Factors - genetics | Down-Regulation - genetics | Homeodomain Proteins - genetics | Mice, Knockout | Proteins - genetics | Transcription Factors - metabolism | Animals | Proteins - metabolism | Sp7 Transcription Factor | Stem Cells - pathology | Wnt3 Protein | Mice | Calcinosis - pathology | Vascular Diseases - metabolism | Wnt3A Protein | Cell Dedifferentiation - genetics | SOX9 Transcription Factor - genetics | Core Binding Factor Alpha 1 Subunit - genetics | Cbfa1 | Runx2
Journal Article
Journal of Clinical Investigation, ISSN 0021-9738, 07/2012, Volume 122, Issue 7, pp. 2405 - 2416
Journal Article
Oncogene, ISSN 0950-9232, 2017, Volume 36, Issue 32, pp. 4573 - 4584
Recent evidences suggest that stearoyl-CoA-desaturase 1 (SCD1), the enzyme involved in monounsaturated fatty acids synthesis, has a role in several cancers. We... 
BIOCHEMISTRY & MOLECULAR BIOLOGY | CENTER STAGE | YAP | FATTY-ACIDS | TAZ | CELL-DEATH | CELL BIOLOGY | HEPATOCELLULAR-CARCINOMA | ONCOLOGY | PATHWAY | THERAPEUTIC TARGET | GENETICS & HEREDITY | EXPRESSION | TUMORIGENESIS | Immunohistochemistry | Wnt3A Protein - metabolism | Adenocarcinoma - pathology | Prognosis | Adenocarcinoma of Lung | Lung Neoplasms - mortality | Humans | Lung Neoplasms - metabolism | Lung Neoplasms - pathology | Male | Intracellular Signaling Peptides and Proteins - metabolism | Neoplasm Proteins - metabolism | Phosphoproteins - metabolism | RNA, Messenger - metabolism | Adenocarcinoma - metabolism | Cell Nucleus - metabolism | Neoplastic Stem Cells - metabolism | HEK293 Cells | Female | Inhibitor of Apoptosis Proteins - metabolism | Protein Stability | Fatty Acids - metabolism | Protein-Serine-Threonine Kinases - metabolism | Down-Regulation | Stearoyl-CoA Desaturase - antagonists & inhibitors | Survivin | Stearoyl-CoA Desaturase - genetics | Axin Signaling Complex - metabolism | Stearoyl-CoA Desaturase - metabolism | Primary Cell Culture | Adaptor Proteins, Signal Transducing - metabolism | Adenocarcinoma - mortality | Care and treatment | Monounsaturated fatty acids | Research | Gene expression | Lung cancer | Stem cells | Adenocarcinoma | Cell survival | Transcription | Data processing | Desaturase | Fatty acids | Survival | Yes-associated protein | β-catenin | Localization | Bioinformatics | Index Medicus
Journal Article
Cell, ISSN 0092-8674, 2004, Volume 119, Issue 1, pp. 97 - 108
The Ryk receptor belongs to the atypical receptor tyrosine kinase family. It is a new member of the family of Wnt receptor proteins. However, the molecular... 
GENE LINOTTE | DROSOPHILA DERAILED RECEPTOR | NEURAL CREST DEVELOPMENT | PROTEIN | WNT/BETA-CATENIN | BIOCHEMISTRY & MOLECULAR BIOLOGY | NEURONAL PATHWAY SELECTION | XENOPUS EMBRYOS | TRANSCRIPTION FACTOR LEF-1 | BETA-CATENIN | INT-1 PROTOONCOGENE | CELL BIOLOGY | Wnt1 Protein | Protein Binding - genetics | Central Nervous System - metabolism | Humans | Wnt Proteins | Receptors, Neurotransmitter - genetics | Central Nervous System - embryology | Embryo, Mammalian - metabolism | DNA-Binding Proteins - metabolism | Lymphoid Enhancer-Binding Factor 1 | Cell Differentiation - genetics | Genes, Regulator - genetics | Phosphoproteins | Dishevelled Proteins | Frizzled Receptors | Proto-Oncogene Proteins - metabolism | Cell Line | Drosophila Proteins | Receptors, G-Protein-Coupled | Mice, Transgenic | Proto-Oncogene Proteins - genetics | Protein Structure, Tertiary - genetics | Transcription Factors - genetics | DNA-Binding Proteins - genetics | Receptor Protein-Tyrosine Kinases - metabolism | Macromolecular Substances | Proteins - genetics | Transcription Factors - metabolism | Adaptor Proteins, Signal Transducing | Animals | Growth Cones - metabolism | Proteins - metabolism | Central Nervous System - cytology | Embryo, Mammalian - embryology | Growth Cones - ultrastructure | Receptor Protein-Tyrosine Kinases - genetics | Embryo, Mammalian - cytology | Wnt3 Protein | Mice | RNA, Small Interfering | Receptors, Neurotransmitter - metabolism | Wnt3A Protein | Homology (Biology) | Genetic aspects | Research | Drosophila | Tyrosine metabolism
Journal Article
Nature Cell Biology, ISSN 1465-7392, 09/2011, Volume 13, Issue 9, pp. 1070 - 1077
Journal Article