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Cell (Cambridge), ISSN 0092-8674, 11/2001, Volume 107, Issue 4, pp. 513 - 523
In humans, low peak bone mass is a significant risk factor for osteoporosis. We report that LRP5, encoding the low-density lipoprotein receptor-related protein 5, affects bone mass accrual during growth... 
Biochemistry & Molecular Biology | Life Sciences & Biomedicine | Science & Technology | Cell Biology | Wnt2 Protein | Humans | Child, Preschool | Male | Bone Density - genetics | Wnt Proteins | Mesoderm - cytology | Wnt-5a Protein | Eye - embryology | Osteoporosis - genetics | Animals, Outbred Strains | Dishevelled Proteins | Bone Morphogenetic Proteins - pharmacology | Child | Organ Culture Techniques | Transforming Growth Factor beta | Signal Transduction | Chromosomes, Human, Pair 11 - genetics | Adaptor Proteins, Signal Transducing | Skull - cytology | Wnt3 Protein | Mice | Receptors, LDL - physiology | COS Cells | Species Specificity | LDL-Receptor Related Proteins | DNA, Complementary - genetics | Recombinant Fusion Proteins - physiology | Cercopithecus aethiops | Culture Media, Conditioned - pharmacology | Recombinant Proteins | Transfection | Receptors, LDL - deficiency | Stromal Cells - drug effects | Adult | Female | Phosphoproteins - physiology | Proteins - physiology | Receptors, LDL - genetics | Bone Morphogenetic Protein 2 | Low Density Lipoprotein Receptor-Related Protein-5 | Mice, Inbred C57BL | Zebrafish Proteins | Proto-Oncogene Proteins - genetics | Phosphoproteins - genetics | Eye Abnormalities - genetics | Genes, Recessive | Syndrome | Proteins - genetics | Animals | Proto-Oncogene Proteins - physiology | Heterozygote | Osteoblasts - metabolism | Stromal Cells - cytology | Wnt4 Protein | Osteoporosis | Bones | Density | Low density lipoproteins | Proteins | Cell research | Lipoproteins | Growth | Analysis | Physiological aspects | LDL receptor-related protein 5 | LRP5 protein | low density lipoprotein receptor-related protein 5 | osteoporosis-pseudoglioma syndrome | Index Medicus | Receptors, LDL | Mesoderm | Osteoblasts | Recombinant Fusion Proteins | Eye | Life Sciences | Stromal Cells | Eye Abnormalities | Phosphoproteins | Proto-Oncogene Proteins | Bone Density | Biochemistry, Molecular Biology | Culture Media, Conditioned | Skull | Chromosomes, Human, Pair 11 | Bone Morphogenetic Proteins | DNA, Complementary
Journal Article
PLoS biology, ISSN 1545-7885, 05/2006, Volume 4, Issue 6, pp. e187 - 1009
Journal Article
PloS one, ISSN 1932-6203, 01/2012, Volume 7, Issue 1, pp. e29976 - e29976
Neuromuscular junction (NMJ) formation requires the highly coordinated communication of several reciprocal signaling processes between motoneurons and their... 
Science & Technology - Other Topics | Multidisciplinary Sciences | Science & Technology | Phosphorylation | Wnt4 Protein - metabolism | Vertebrates - genetics | Neuromuscular Junction - metabolism | Humans | Vertebrates - embryology | Cercopithecus aethiops | Wnt4 Protein - deficiency | Muscles - pathology | Embryo, Mammalian - metabolism | Neuromuscular Junction - embryology | Wnt4 Protein - genetics | Gene Expression Regulation, Developmental | HEK293 Cells | Neuromuscular Junction - pathology | Biomarkers - metabolism | Muscle Cells - pathology | Muscles - ultrastructure | Receptors, Cholinergic - metabolism | Muscles - embryology | Muscle Cells - metabolism | Receptor Protein-Tyrosine Kinases - metabolism | Neuromuscular Junction - ultrastructure | Animals | Muscles - innervation | Protein Binding | Mice | Body Patterning - genetics | COS Cells | Cluster Analysis | Proteins | Cell differentiation | Analysis | Target recognition | Wnt protein | Synaptogenesis | Innervation | Differentiation (biology) | Kinases | Acetylcholinesterase | Signal transduction | Immunology | Rodents | Clusters | Localization | Rapsyn | Cues | Nerve endings | Motor neurons | Phenotypes | Myotubes | Muscles | Polymerase chain reaction | Vertebrates | Axons | Signaling | Microscopy | Neural networks | Acetylcholine receptors | Low density lipoprotein receptors | Neuromuscular junctions | Receptor density | Index Medicus | Biological Markers | Embryo, Mammalian | Biochemistry, Molecular Biology | Receptor Protein-Tyrosine Kinases | Life Sciences | Neuromuscular Junction | Body Patterning | Muscle Cells | Molecular biology | Receptors, Cholinergic | Wnt4 Protein
Journal Article
Journal Article
Journal Article
PloS one, ISSN 1932-6203, 04/2013, Volume 8, Issue 4, pp. e60244 - e60244
Endocardial to mesenchymal transformation (EMT) is a fundamental cellular process required for heart valve formation. Notch, Wnt and Bmp pathways are known to... 
Science & Technology - Other Topics | Multidisciplinary Sciences | Science & Technology | Wnt4 Protein - metabolism | Embryo, Mammalian | Heart Valves - metabolism | Epithelial-Mesenchymal Transition - genetics | Endocardium - metabolism | Wnt4 Protein - genetics | Intercellular Signaling Peptides and Proteins - metabolism | Gene Expression Regulation, Developmental | Serrate-Jagged Proteins | Bone Morphogenetic Protein 2 - metabolism | Myocardium - metabolism | Membrane Proteins - metabolism | Heart Valves - embryology | Extracellular Matrix Proteins - metabolism | Jagged-1 Protein | Calcium-Binding Proteins - metabolism | Bone Morphogenetic Protein 2 - genetics | Signal Transduction | Endocardium - embryology | Membrane Proteins - genetics | Extracellular Matrix Proteins - genetics | Intercellular Signaling Peptides and Proteins - genetics | Mice, Transgenic | Receptor, Notch1 - metabolism | Animals | Organogenesis - genetics | Mice | Receptor, Notch1 - genetics | Calcium-Binding Proteins - genetics | Cellular signal transduction | Research | Wnt proteins | Heart valves | Heart | Transformation | Immunoglobulins | Bone morphogenetic protein 2 | Wnt protein | Mesenchyme | Laboratories | Paracrine signalling | Histology | Ribonucleic acid--RNA | Embryos | Defects | Morphogenesis | Medicine | Signal transduction | Cell growth | Hospitals | Pathways | Rodents | Myocardium | Notch protein | Jagged1 protein | Cardiology | Index Medicus | RNA | Ribonucleic acid
Journal Article
Journal Article