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1994, Literatura e crítica, ISBN 8478242104, Volume 1, 94
Book
Optics Express, ISSN 1094-4087, 2019, Volume 27, Issue 13, pp. 18282 - 18295
Simultaneous linear unmixing of excitation-emission spectra (ExEm-unmixing)-based fluorescence resonance energy transfer (FRET) two-hybrid assay method, named... 
BCL-2 | BAX | OPTICS | PROTEINS | BCL-X(L) | BH3 DOMAIN
Journal Article
NATURE REVIEWS CANCER, ISSN 1474-175X, 12/2008, Volume 8, Issue 12, pp. 976 - 990
Just over 25 years ago, MYC, the human homologue of a retroviral oncogene, was identified. Since that time, MYC research has been intense and the advances... 
PLURIPOTENT STEM-CELLS | BCL-X-L | RNA-POLYMERASE-I | AVIAN MYELOCYTOMATOSIS VIRUS | ONCOLOGY | INDUCED APOPTOSIS | TRANSCRIPTION FACTOR NETWORK | DNA-DAMAGE RESPONSE | HUMAN C-MYC | MOUSE ERYTHROLEUKEMIA-CELLS | TRANSGENIC MICE
Journal Article
BLOOD, ISSN 0006-4971, 12/2016, Volume 128, Issue 23, pp. 2655 - 2665
The intercellular crosstalk between hematological malignancies and the tumor microenvironment is mediated by cell-to-cell interactions and soluble factors. One... 
PROTEIN | CASPASE-3 | BAX | DEATH | SORAFENIB | HEMATOLOGY | BCL-X(L) | MODULATION
Journal Article
AUTOPHAGY, ISSN 1554-8627, 07/2009, Volume 5, Issue 5, pp. 720 - 722
Beclin 1, an essential autophagic protein, is a BH3-only protein that binds Bcl-2 anti-apoptotic family members. The dissociation of Beclin I from the Bcl-2... 
Bcl-2 | COMPLEX | autophagy | PROTEIN | Bcl-X-L | DAP-kinase | beclin 1 | BH3 DOMAIN | CELL BIOLOGY
Journal Article
NATURE CELL BIOLOGY, ISSN 1465-7392, 07/2013, Volume 15, Issue 7, pp. 773 - 773
Following exocytosis, the rate of recovery of neurotransmitter release is determined by vesicle retrieval from the plasma membrane and by recruitment of... 
CENTRAL SYNAPSES | CYTOCHROME-C | BCL-X-L | APOPTOSIS | TRANSMISSION | TERMINALS | POOL | PROTEINS | HIPPOCAMPAL-NEURONS | MITOCHONDRIAL FISSION | CELL BIOLOGY
Journal Article
CELL DEATH & DISEASE, ISSN 2041-4889, 10/2014, Volume 5
We sought to identify miRNAs that can efficiently induce apoptosis in ovarian cancer cells by overcoming BCL-X-L and MCL1 anti-apoptotic activity, using... 
CELLS | INVASION | THERAPY | MCL-1 | TARGETS | MICRORNA EXPRESSION | CANCER | BCL-X(L) | STRATEGIES | CELL BIOLOGY
Journal Article
Book
Nature Immunology, ISSN 1529-2908, 03/2002, Volume 3, Issue 3, pp. 221 - 227
The choice between life and death is one of the major events in regulation of the immune system. T cells that specifically recognize viral or bacterial... 
INDUCED CELL-DEATH | ALPHA-INDUCED APOPTOSIS | NECROSIS-FACTOR ALPHA | CYTOKINE PRODUCTION | IKK-BETA SUBUNIT | NEGATIVE REGULATION | LIVER DEGENERATION | EMBRYONIC LETHALITY | IMMUNOLOGY | MICE LACKING | BCL-X(L) EXPRESSION
Journal Article
Current Opinion in Cell Biology, ISSN 0955-0674, 2010, Volume 22, Issue 2, pp. 140 - 149
Journal Article
GENES & DEVELOPMENT, ISSN 0890-9369, 06/2005, Volume 19, Issue 11, pp. 1294 - 1305
Commitment of cells to apoptosis is governed largely by the interaction between members of the Bcl-2 protein family. its three subfamilies have distinct roles:... 
Bcl-2 | MITOCHONDRIAL APOPTOSIS | MEMBRANE | apoptosis | DEVELOPMENTAL BIOLOGY | Bak | INITIATE APOPTOSIS | BH3-only | CELL-DEATH | BH3 DOMAIN | FAMILY | CYTOCHROME-C | Mcl-1 | IN-VIVO | GENETICS & HEREDITY | X-DEFICIENT MICE | ADENOVIRUS E1B 19K | Bcl-x(L) | Genetic research | DNA binding proteins | Research | Apoptosis
Journal Article
MOLECULAR THERAPY, ISSN 1525-0016, 02/2010, Volume 18, Issue 2, pp. 413 - 420
To enhance the strength of activation afforded by tumor antigen-specific receptors, we investigated the effect of adding combined CD28 and 4-1BB costimulatory... 
MEDICINE, RESEARCH & EXPERIMENTAL | BCL-X-L | IMMUNITY | EFFECTOR FUNCTION | PROTEIN-KINASE B | BIOTECHNOLOGY & APPLIED MICROBIOLOGY | IN-VIVO | GENETICS & HEREDITY | COSTIMULATION | LIGAND | ADOPTIVE IMMUNOTHERAPY | ANTITUMOR EFFICACY | LYMPHOCYTES
Journal Article
JOURNAL OF BIOENERGETICS AND BIOMEMBRANES, ISSN 0145-479X, 06/2016, Volume 48, Issue 3, pp. 211 - 225
Bcl-2 family proteins are known to competitively regulate Ca2+; however, the specific inter-organelle signaling pathways and related cellular functions are not... 
Mitochondria | BIOPHYSICS | Bioenergetics | MAM | IPR3 | Bcl-x(L) | Calicum signaling | CELL BIOLOGY
Journal Article
SCIENTIFIC REPORTS, ISSN 2045-2322, 06/2016, Volume 6
ABT-199, a potent and selective small-molecule antagonist of BCL-2, is being clinically vetted as pharmacotherapy for the treatment of acute myeloid leukemia... 
BCL-X-L | CELLS | POTENT | ACTIVATION | MCL-1 | MULTIDISCIPLINARY SCIENCES | ABT-737 | CHRONIC LYMPHOCYTIC-LEUKEMIA | MEK INHIBITORS | NAVITOCLAX | COMBINED BRAF
Journal Article
ONCOGENE, ISSN 0950-9232, 06/2007, Volume 26, Issue 27, pp. 3972 - 3979
ABT-737 is a subnanomolar inhibitor of the antiapoptotic proteins Bcl-2, Bcl-XL and Bcl-w. Although ABT-737 triggers extensive cell death in many small-cell... 
CELLS | off-target | seed | RNA | BIOCHEMISTRY & MOLECULAR BIOLOGY | Bcl-X-L | ABT-737 | siRNA | CELL BIOLOGY | Mcl-1 | ONCOLOGY | GENETICS & HEREDITY | PROTEINS | EXPRESSION
Journal Article
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