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hemophagocytic lymphohistiocytosis (42) 42
protein (42) 42
genetic diseases, x-linked - genetics (41) 41
kinases (41) 41
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x-linked adrenoleukodystrophy (32) 32
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Immunity, ISSN 1074-7613, 02/2012, Volume 36, Issue 2, pp. 215 - 227
Interleukin-1β (IL-1β) is a potent inflammatory cytokine that is usually cleaved and activated by inflammasome-associated caspase-1. To determine whether IL-1β... 
STERILE INFLAMMATORY RESPONSE | PROGRAMMED NECROSIS | CASPASE-8 | IL-1-BETA | NLRP3 INFLAMMASOME | TNF-ALPHA | IMMUNOLOGY | NF-KAPPA-B | CIAP1 | NALP3 INFLAMMASOME | CELL-DEATH | Receptor-Interacting Protein Serine-Threonine Kinases - metabolism | X-Linked Inhibitor of Apoptosis Protein - deficiency | Inflammasomes - metabolism | Reactive Oxygen Species - metabolism | Inhibitor of Apoptosis Proteins - genetics | NLR Family, Pyrin Domain-Containing 3 Protein | Caspase 1 - metabolism | Baculoviral IAP Repeat-Containing 3 Protein | Mitochondrial Proteins - agonists | Carrier Proteins - agonists | Inhibitor of Apoptosis Proteins - deficiency | Molecular Mimicry | Interleukin-1beta - metabolism | Inhibitor of Apoptosis Proteins - antagonists & inhibitors | Inhibitor of Apoptosis Proteins - metabolism | Macrophages - immunology | Macrophages - cytology | X-Linked Inhibitor of Apoptosis Protein - genetics | Mice, Knockout | Ubiquitin-Protein Ligases | Macrophages - metabolism | Animals | Carrier Proteins - metabolism | Inflammasomes - immunology | X-Linked Inhibitor of Apoptosis Protein - metabolism | Macrophages - drug effects | Mice | Apoptosis | Proteins | Interleukins | Genes | Membranes | Mammals | Immune system | Caspase-8 | DIABLO protein | Cell activation | IAP protein | Reactive oxygen species | Interleukin 1 | Toll-like receptors | XIAP protein | Inflammation | Macrophages | Caspase-1 | Index Medicus
Journal Article
Journal Article
Nature, ISSN 0028-0836, 08/2009, Volume 460, Issue 7258, pp. 1035 - 1039
Journal Article
Journal Article
Gut, ISSN 0017-5749, 06/2017, Volume 66, Issue 6, pp. 1060 - 1073
ObjectivePatients with Niemann–Pick disease type C1 (NPC1), a lysosomal lipid storage disorder that causes neurodegeneration and liver damage, can present with... 
IBD-GENETICS | IBD CLINICAL | IMMUNODEFICIENCY | IBD BASIC RESEARCH | Crohn'S DISEASE | MIGLUSTAT THERAPY | PATHOGENESIS | APOPTOSIS | DENDRITIC CELLS | MACROPHAGES | SUSCEPTIBILITY | ILEAL MUCOSA | PHAGOSOME PROTEOME | GASTROENTEROLOGY & HEPATOLOGY | BOWEL-DISEASE | INNATE IMMUNITY | Tumor Necrosis Factor-alpha - metabolism | Crohn Disease - genetics | X-Linked Inhibitor of Apoptosis Protein - deficiency | Humans | Child, Preschool | Lysosomes | Male | Nod2 Signaling Adaptor Protein - genetics | Leukocytes, Mononuclear | Pyridazines - pharmacology | Niemann-Pick Disease, Type C - physiopathology | Autophagy - drug effects | Crohn Disease - complications | Receptor-Interacting Protein Serine-Threonine Kinase 2 - metabolism | Young Adult | Gentamicins - pharmacology | Adult | Bacteria | Female | Genetic Diseases, X-Linked - genetics | Autophagy - genetics | Child | Receptor-Interacting Protein Serine-Threonine Kinase 2 - antagonists & inhibitors | Macrophages - physiology | Granuloma - genetics | Cells, Cultured | Chlorpromazine - pharmacology | Imidazoles - pharmacology | Acetylmuramyl-Alanyl-Isoglutamine - metabolism | X-Linked Inhibitor of Apoptosis Protein - genetics | Acetylmuramyl-Alanyl-Isoglutamine - pharmacology | Granuloma - pathology | Nod2 Signaling Adaptor Protein - metabolism | Crohn Disease - pathology | Dopamine Antagonists - pharmacology | Adolescent | X-Linked Inhibitor of Apoptosis Protein - metabolism | Macrophages - drug effects | Anti-Bacterial Agents - pharmacology | Protein Kinase Inhibitors - pharmacology | Mutation | Niemann-Pick Disease, Type C - complications | Niemann-Pick Disease, Type C - genetics | Autophagy (Cytology) | Inflammatory bowel diseases | Gastrointestinal diseases | Causes of | Colorectal diseases | Crohn's disease | Research | Niemann-Pick disease | Salmonella | Granuloma | Muramyl dipeptide | Liver | XIAP protein | Kinases | Macrophages | Autophagy | Defects | Genotype & phenotype | Cell activation | Intestine | Neurodegeneration | Npc1 protein | Age | NOD2 protein | Oligomerization | Dendritic cells | Cytokines | Blood & organ donations | Inflammation | Patients | Crohns disease | Studies | Inflammatory bowel disease | Monocytes | Proteomics | Colitis | Adapter proteins | Phagocytosis | Apoptosis | Index Medicus | Abridged Index Medicus | IBD - GENETICS | CROHN'S DISEASE | Inflammatory Bowel Disease | 1506
Journal Article
Journal of Clinical Immunology, ISSN 0271-9142, 6/2012, Volume 32, Issue 3, pp. 411 - 420
Deficiency of X-linked inhibitor of apoptosis (XIAP) caused by XIAP/BIRC4 gene mutations is an inherited immune defect recognized as X-linked... 
Medical Microbiology | Biomedicine | Immunology | Internal Medicine | Infectious Diseases | hemophagocytic lymphohistiocytosis | invariant natural killer T cell | X-linked lymphoproliferative syndrome | X-linked inhibitor of apoptosis | Epstein–Barr virus | Epstein-Barr virus | APOPTOSIS | SEVERE COMBINED IMMUNODEFICIENCY | FAMILIAL HEMOPHAGOCYTIC LYMPHOHISTIOCYTOSIS | ENCODING GENE | IMMUNOLOGY | LINKED LYMPHOPROLIFERATIVE-DISEASE | NKT-CELL-DEVELOPMENT | FLOW-CYTOMETRY | MUTATIONS | T-LYMPHOCYTES | GRANZYME-B | T-Lymphocytes, Cytotoxic - immunology | X-Linked Inhibitor of Apoptosis Protein - deficiency | Humans | Japan | Child, Preschool | Lymphohistiocytosis, Hemophagocytic - diagnosis | Infant | Male | Lymphoproliferative Disorders - genetics | Lymphoproliferative Disorders - immunology | X-Linked Inhibitor of Apoptosis Protein - immunology | X-Linked Inhibitor of Apoptosis Protein - genetics | Lymphoproliferative Disorders - diagnosis | Leukocytes, Mononuclear - immunology | Adolescent | Lymphocyte Count | Mutation | Lymphohistiocytosis, Hemophagocytic - genetics | Child | Lymphohistiocytosis, Hemophagocytic - immunology | Natural Killer T-Cells - immunology | Virus diseases | Medical colleges | Anopheles | Gene mutations | Lymphocytes | Genes | Genetic research | Universities and colleges | Colitis | T cells | Health aspects | Apoptosis | Index Medicus | CD8 antigen | Recurrent infection | X chromosome | Cytotoxicity | XIAP protein | Lymphocytes T | Histiocytosis | Cord blood | Point mutation | Children | Natural killer cells | Lymphocytosis
Journal Article
INTERNATIONAL JOURNAL OF COLORECTAL DISEASE, ISSN 0179-1958, 06/2016, Volume 31, Issue 6, pp. 1235 - 1236
Journal Article
Journal Article
Journal Article