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1. Full Text Overcoming chemotherapy drug resistance by targeting inhibitors of apoptosis proteins (IAPs)
by Rathore, Rama and McCallum, Jennifer E and Varghese, Elizabeth and Florea, Ana-Maria and Büsselberg, Dietrich
Apoptosis (London), ISSN 1360-8185, 07/2017, Volume 22, Issue 7, pp. 898 - 919
Chemotherapy resistance | Intrinsic apoptotic pathway | Combination therapy | Extrinsic apoptotic pathway | Inhibitors of apoptosis proteins | Biochemistry & Molecular Biology | Life Sciences & Biomedicine | Science & Technology | Cell Biology | Apoptosis - drug effects | Inhibitor of Apoptosis Proteins - genetics | Humans | Intracellular Signaling Peptides and Proteins - antagonists & inhibitors | Mitochondrial Proteins - antagonists & inhibitors | Apoptosis - genetics | Mitochondrial Proteins - genetics | X-Linked Inhibitor of Apoptosis Protein - genetics | Neoplasms - drug therapy | Drug Resistance, Neoplasm - genetics | Neoplasms - genetics | Inhibitor of Apoptosis Proteins - antagonists & inhibitors | Neoplasms - pathology | Intracellular Signaling Peptides and Proteins - genetics | TNF-Related Apoptosis-Inducing Ligand - genetics | Proteins | Viral antibodies | Chemotherapy | Antibodies | Metastasis | Drug resistance | Cancer | Apoptosis | Biotechnology | XIAP protein | Infections | Metastases | Anticancer properties | Analogs | Mitochondria | Antagonism | Cell cycle | Cell survival | Mortality | Caspase | Survivin | Tumor cell lines | Survival | DIABLO protein | Inhibitors | Reviews | Cell death | TRAIL protein | Index Medicus | Review
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2. Full Text Inhibitor of Apoptosis Proteins Limit RIP3 Kinase-Dependent Interleukin-1 Activation
by Vince, James E and Wong, W. Wei-Lynn and Gentle, Ian and Lawlor, Kate E and Allam, Ramanjaneyulu and O'Reilly, Lorraine and Mason, Kylie and Gross, Olaf and Ma, Stephen and Guarda, Greta and Anderton, Holly and Castillo, Rosa and Häcker, Georg and Silke, John and Tschopp, Jürg
Immunity (Cambridge, Mass.), ISSN 1074-7613, 02/2012, Volume 36, Issue 2, pp. 215 - 227
Life Sciences & Biomedicine | Immunology | Science & Technology | Receptor-Interacting Protein Serine-Threonine Kinases - metabolism | X-Linked Inhibitor of Apoptosis Protein - deficiency | Inflammasomes - metabolism | Reactive Oxygen Species - metabolism | Inhibitor of Apoptosis Proteins - genetics | NLR Family, Pyrin Domain-Containing 3 Protein | Caspase 1 - metabolism | Baculoviral IAP Repeat-Containing 3 Protein | Mitochondrial Proteins - agonists | Carrier Proteins - agonists | Inhibitor of Apoptosis Proteins - deficiency | Molecular Mimicry | Interleukin-1beta - metabolism | Inhibitor of Apoptosis Proteins - antagonists & inhibitors | Inhibitor of Apoptosis Proteins - metabolism | Macrophages - immunology | Macrophages - cytology | X-Linked Inhibitor of Apoptosis Protein - genetics | Mice, Knockout | Ubiquitin-Protein Ligases | Macrophages - metabolism | Animals | Carrier Proteins - metabolism | Inflammasomes - immunology | X-Linked Inhibitor of Apoptosis Protein - metabolism | Macrophages - drug effects | Mice | Apoptosis | Proteins | Interleukins | Genes | Membranes | Mammals | Immune system | Caspase-8 | DIABLO protein | Cell activation | IAP protein | Reactive oxygen species | Interleukin 1 | Toll-like receptors | XIAP protein | Inflammation | Macrophages | Caspase-1 | Index Medicus
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3. Full Text Inhibitors of apoptosis proteins (IAPs) expression and their prognostic significance in hepatocellular carcinoma
by Augello, Claudia and Caruso, Luca and Maggioni, Marco and Donadon, Matteo and Montorsi, Marco and Santambrogio, Roberto and Torzilli, Guido and Vaira, Valentina and Pellegrini, Caterina and Roncalli, Massimo and Coggi, Guido and Bosari, Silvano
BMC cancer, ISSN 1471-2407, 04/2009, Volume 9, Issue 1, pp. 125 - 125
Life Sciences & Biomedicine | Oncology | Science & Technology | Immunohistochemistry | Prognosis | Follow-Up Studies | Microtubule-Associated Proteins - genetics | Inhibitor of Apoptosis Proteins - genetics | Microtubule-Associated Proteins - metabolism | Humans | Middle Aged | Gene Expression Regulation, Neoplastic | Male | Intracellular Signaling Peptides and Proteins - metabolism | Mitochondrial Proteins - genetics | Neoplasm Proteins - metabolism | Mitochondrial Proteins - metabolism | Carcinoma, Hepatocellular - genetics | Aged, 80 and over | Adult | Female | Liver Neoplasms - pathology | Inhibitor of Apoptosis Proteins - metabolism | Neoplasm Proteins - genetics | Intracellular Signaling Peptides and Proteins - genetics | Liver Neoplasms - genetics | Kaplan-Meier Estimate | Chi-Square Distribution | Reverse Transcriptase Polymerase Chain Reaction | X-Linked Inhibitor of Apoptosis Protein - genetics | Analysis of Variance | Adaptor Proteins, Signal Transducing - genetics | Carcinoma, Hepatocellular - pathology | Liver Neoplasms - metabolism | X-Linked Inhibitor of Apoptosis Protein - metabolism | Aged | Adaptor Proteins, Signal Transducing - metabolism | Apoptosis | Carcinoma, Hepatocellular - metabolism | Control | Care and treatment | Usage | Genetic aspects | Research | Hepatoma | Gene expression | Health aspects | Index Medicus
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4. Full Text Circular RNA VMA21 protects against intervertebral disc degeneration through targeting miR-200c and X linked inhibitor-of-apoptosis protein
by Cheng, Xiaofei and Zhang, Liang and Zhang, Kai and Zhang, Guoying and Hu, Ying and Sun, Xiaojiang and Zhao, Changqing and Li, Hua and Li, Yan Michael and Zhao, Jie
Annals of the rheumatic diseases, ISSN 0003-4967, 05/2018, Volume 77, Issue 5, pp. 770 - 779
cytokines | inflammation | TNF-alpha | low back pain | osteoarthritis | Life Sciences & Biomedicine | Rheumatology | Science & Technology | Vacuolar Proton-Translocating ATPases - genetics | Nucleus Pulposus - metabolism | Humans | Cell Survival - genetics | Extracellular Matrix - metabolism | Rats | Apoptosis - genetics | Signal Transduction - genetics | X-Linked Inhibitor of Apoptosis Protein - genetics | RNA - genetics | Animals | MicroRNAs - genetics | Intervertebral Disc Degeneration - genetics | Animal models | Back pain | Cytokines | XIAP protein | Inflammation | Arthritis | mRNA | Nucleus pulposus | Kinases | Intervertebral discs | Gene expression | Nuclei | Proteins | Rodents | Collagen | Circular RNA | Extracellular matrix | TNF inhibitors | Tumor necrosis factor-TNF | miRNA | Degeneration | Binding sites | Apoptosis | Index Medicus | 2311 | Basic and Translational Research | 1506 | tnf-alpha
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5. Full Text The inhibitors of apoptosis (IAPs) as cancer targets
by Hunter, Allison M and LaCasse, Eric C and Korneluk, Robert G
Apoptosis (London), ISSN 1360-8185, 9/2007, Volume 12, Issue 9, pp. 1543 - 1568
Biochemistry, general | TNFR | TRAF | Oncology | NFkB | Virology | Cell Biology | Biomedicine | Cancer Research | IAPs | Caspases | Smac | Knock out mice | Apoptosis | Cancer | Biochemistry & Molecular Biology | Life Sciences & Biomedicine | Science & Technology | Caspases - physiology | Proto-Oncogene Proteins c-bcl-2 - physiology | Apoptosis - drug effects | Inhibitor of Apoptosis Proteins - genetics | Humans | Neoplasm Proteins - physiology | Serine Endopeptidases - physiology | Neoplasm Proteins - antagonists & inhibitors | Inhibitor of Apoptosis Proteins - physiology | X-Linked Inhibitor of Apoptosis Protein - antagonists & inhibitors | Neoplasms - genetics | Inhibitor of Apoptosis Proteins - antagonists & inhibitors | Oligonucleotides, Antisense - therapeutic use | Intracellular Signaling Peptides and Proteins - therapeutic use | Mitochondrial Proteins - therapeutic use | Peptide Termination Factors - physiology | Mitochondrial Proteins - physiology | Neoplasm Proteins - therapeutic use | Microtubule-Associated Proteins - antagonists & inhibitors | Caspase Inhibitors | High-Temperature Requirement A Serine Peptidase 2 | Neoplasms - drug therapy | Animals | Protein Kinases - physiology | Checkpoint Kinase 1 | Enzyme Activation | Genetic Vectors | Intracellular Signaling Peptides and Proteins - physiology | Proteins | Cancer therapies | Index Medicus
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6. Full Text Degradation of Survivin by the X-linked Inhibitor of Apoptosis (XIAP)-XAF1 Complex
by Vinay Arora and Herman H. Cheung and Stéphanie Plenchette and O. Cristina Micali and Peter Liston and Robert G. Korneluk
The Journal of biological chemistry, ISSN 0021-9258, 09/2007, Volume 282, Issue 36, pp. 26202 - 26209
Life Sciences & Biomedicine | Biochemistry & Molecular Biology | Science & Technology | Microtubule-Associated Proteins - genetics | Apoptosis - drug effects | Inhibitor of Apoptosis Proteins - genetics | Microtubule-Associated Proteins - metabolism | Humans | Neuronal Apoptosis-Inhibitory Protein - genetics | Ubiquitin - metabolism | Multiprotein Complexes - genetics | Baculoviral IAP Repeat-Containing 3 Protein | Neoplasm Proteins - metabolism | Multiprotein Complexes - metabolism | Tumor Suppressor Proteins - genetics | Inhibitor of Apoptosis Proteins - metabolism | Neoplasm Proteins - genetics | Antiviral Agents - pharmacology | Tumor Suppressor Proteins - metabolism | Ubiquitin-Protein Ligases - metabolism | Intracellular Signaling Peptides and Proteins | Ubiquitin - genetics | Down-Regulation - drug effects | Neuronal Apoptosis-Inhibitory Protein - metabolism | X-Linked Inhibitor of Apoptosis Protein - genetics | Down-Regulation - physiology | Leupeptins - pharmacology | Mitosis - drug effects | Interferon-beta - pharmacology | Mitosis - physiology | Cysteine Proteinase Inhibitors - pharmacology | Adaptor Proteins, Signal Transducing - genetics | X-Linked Inhibitor of Apoptosis Protein - metabolism | Cell Line, Tumor | Apoptosis - physiology | Adaptor Proteins, Signal Transducing - metabolism | Ubiquitin-Protein Ligases - genetics |