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1. Full Text XIAP discriminates between type I and type II FAS-induced apoptosis
by Jost, Philipp J and Gray, Daniel and Borner, Christoph and Thomas, Helen E and McKenzie, Mark D and Silke, John and Nachbur, Ueli and Strasser, Andreas and Huang, David C. S and Kaufmann, Thomas and Grabow, Stephanie and Bouillet, Philippe
Nature, ISSN 0028-0836, 08/2009, Volume 460, Issue 7258, pp. 1035 - 1039
FAS (also called APO-1 and CD95) and its physiological ligand, FASL, regulate apoptosis of unwanted or dangerous cells, functioning as a guardian against... 
CYTOCHROME-C | ACTIVATION | IMMUNE-SYSTEM | PROTEIN | MULTIDISCIPLINARY SCIENCES | ALPHA-DEPENDENT APOPTOSIS | RECEPTOR | SMAC | DEFICIENT MICE | T-LYMPHOCYTES | CELL-DEATH | BH3 Interacting Domain Death Agonist Protein - deficiency | X-Linked Inhibitor of Apoptosis Protein - deficiency | Fas Ligand Protein - metabolism | Male | BH3 Interacting Domain Death Agonist Protein - genetics | Hepatocytes - metabolism | fas Receptor - metabolism | X-Linked Inhibitor of Apoptosis Protein - antagonists & inhibitors | fas Receptor - immunology | Hepatocytes - cytology | Hepatitis - metabolism | Female | Hepatocytes - drug effects | Signal Transduction | Mice, Inbred C57BL | Thymus Gland - cytology | Hepatitis - pathology | fas Receptor - antagonists & inhibitors | Thymus Gland - drug effects | Caspase Inhibitors | X-Linked Inhibitor of Apoptosis Protein - genetics | Biomimetic Materials - pharmacology | Animals | X-Linked Inhibitor of Apoptosis Protein - metabolism | Mice | Enzyme Activation | Apoptosis | Cellular proteins | Enzyme inhibitors | Physiological aspects | Cellular signal transduction | Research | Drug therapy | Health aspects | Cancer | Hepatitis | Rodents | Cancer therapies | Cells | Substrates | Index Medicus
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2. Full Text miR-23a regulation of X-linked inhibitor of apoptosis (XIAP) contributes to sex differences in the response to cerebral ischemia
by Chad Siegel and Jun Li and Fudong Liu and Sharon E. Benashski and Louise D. McCullough
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 7/2011, Volume 108, Issue 28, pp. 11662 - 11667
It is increasingly recognized that the mechanisms underlying ischemic cell death are sexually dimorphic. Stroke-induced cell death in males is initiated by the... 
Messenger RNA | MicroRNA | Ischemia | Cell death | Sex linked differences | Brain ischemia | Strokes | Gene expression regulation | Female animals | Apoptosis | Second mitochondria-derived activator of caspases/direct inhibitor of apoptosis binding protein with low Pi | Spectrin cleavage | Ovariectomy | Middle cerebral artery occlusion | Estrogen | estrogen | OXIDATIVE STRESS | BRAIN-INJURY | spectrin cleavage | MULTIDISCIPLINARY SCIENCES | EXPERIMENTAL STROKE | NEUROPROTECTION | CELL-DEATH | HYPOXIA-ISCHEMIA | IN-VIVO | GENDER | MICE | MICRORNA EXPRESSION | middle cerebral artery occlusion | ovariectomy | second mitochondria-derived activator of caspases/direct inhibitor of apoptosis binding protein with low Pi | Brain Ischemia - genetics | Caspase 3 - metabolism | Brain Ischemia - metabolism | Male | MicroRNAs - metabolism | Mitochondrial Proteins - genetics | RNA, Messenger - metabolism | Brain - metabolism | X-Linked Inhibitor of Apoptosis Protein - antagonists & inhibitors | Mitochondrial Proteins - metabolism | Base Sequence | Female | 3' Untranslated Regions | Mice, Inbred C57BL | RNA, Messenger - genetics | Estradiol - administration & dosage | Binding Sites - genetics | Sex Characteristics | X-Linked Inhibitor of Apoptosis Protein - genetics | Benzoquinones - pharmacology | Brain - drug effects | Carrier Proteins - genetics | Animals | Carrier Proteins - metabolism | Brain Ischemia - pathology | X-Linked Inhibitor of Apoptosis Protein - metabolism | Brain - pathology | Mice | MicroRNAs - genetics | Models, Neurological | Physiological aspects | Cerebral ischemia | Genetic aspects | Health aspects | Proteins | Ribonucleic acid--RNA | Cells | Index Medicus | Brain | Stroke | Translation | Apoptosis-inducing factor | Sex | X chromosome | Sex differences | XIAP protein | mRNA | Caspase-3 | Cytochrome c | Mitochondria | miRNA | Sexual dimorphism | Injuries | Biological Sciences | direct inhibitor of apoptosis binding protein with low Pi | second mitochondria-derived activator of caspases
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3. Full Text A Smac mimetic rescue screen reveals roles for inhibitor of apoptosis proteins in tumor necrosis factor-α signaling
by Gaither, Alex and Porter, Dale and Yao, Yao and Borawski, Jason and Yang, Guang and Donovan, Jerry and Sage, David and Slisz, Joanna and Tran, Mary and Straub, Christopher and Ramsey, Tim and Iourgenko, Vadim and Huang, Alan and Chen, Yan and Schlegel, Robert and Labow, Mark and Fawell, Stephen and Sellers, William R and Zawel, Leigh
Cancer Research, ISSN 0008-5472, 12/2007, Volume 67, Issue 24, pp. 11493 - 11498
Smac mimetic compounds targeting the inhibitor of apoptosis proteins (UP) baculoviral LAP repeat-3 domain are presumed to reduce the threshold for apoptotic... 
SMAC/DIABLO | ACTIVATION | C-IAP1 | EVENTS | ONCOLOGY | CASPASES | BIOLOGY | IAPS | XIAP | CHEMORESISTANCE | CANCER | RNA, Small Interfering - genetics | Signal Transduction | Apoptosis - drug effects | Humans | Mitochondrial Proteins - physiology | Inhibitor of Apoptosis Proteins - physiology | X-Linked Inhibitor of Apoptosis Protein - genetics | Cell Death | Tumor Necrosis Factor-alpha - physiology | Cell Line, Tumor | Conserved Sequence | RNA, Neoplasm - genetics | Female | Apoptosis - physiology | Ovarian Neoplasms | Intracellular Signaling Peptides and Proteins - physiology | Oligopeptides - pharmacology | RNA Interference - physiology | X-Linked Inhibitor of Apoptosis Protein - physiology | Index Medicus
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4. Full Text Quantitative Analysis of Pathways Controlling Extrinsic Apoptosis in Single Cells
by Albeck, John G and Burke, John M and Aldridge, Bree B and Zhang, Mingsheng and Lauffenburger, Douglas A and Sorger, Peter K
Molecular Cell, ISSN 1097-2765, 04/2008, Volume 30, Issue 1, pp. 11 - 25
Apoptosis in response to TRAIL or TNF requires the activation of initiator caspases, which then activate the effector caspases that dismantle cells and cause... 
SYSBIO | CELLCYCLE | DEATH RECEPTORS | EFFECTOR-CASPASE ACTIVATION | PROTEIN | X-LINKED INHIBITOR | BIOCHEMISTRY & MOLECULAR BIOLOGY | SURVIVING APOPTOSIS | SMAC/DIABLO RELEASE | RESONANCE ENERGY-TRANSFER | MITOCHONDRIAL-MEMBRANE | CYTOCHROME-C RELEASE | OLIGOMERIZATION | CELL BIOLOGY | Humans | Intracellular Signaling Peptides and Proteins - metabolism | Mathematics | Mitochondrial Proteins - genetics | Recombinant Fusion Proteins - metabolism | Proto-Oncogene Proteins c-bcl-2 - metabolism | Caspases - metabolism | RNA Interference | Mitochondrial Proteins - metabolism | Intracellular Signaling Peptides and Proteins - genetics | Models, Theoretical | Mitochondria - metabolism | Membrane Potentials - physiology | TNF-Related Apoptosis-Inducing Ligand - metabolism | X-Linked Inhibitor of Apoptosis Protein - genetics | Poly(ADP-ribose) Polymerases - metabolism | Poly(ADP-ribose) Polymerases - genetics | X-Linked Inhibitor of Apoptosis Protein - metabolism | Recombinant Fusion Proteins - genetics | Luminescent Proteins - genetics | Signal Transduction - physiology | Apoptosis - physiology | Enzyme Activation | HeLa Cells | Proto-Oncogene Proteins c-bcl-2 - genetics | TNF-Related Apoptosis-Inducing Ligand - genetics | Luminescent Proteins - metabolism | Analysis | Apoptosis | Index Medicus | Bcl-2 | proteasome | TRAIL | biological modeling | FRET reporter | apoptosis | XIAP | TNF | caspase | computational
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5. Full Text Circular RNA VMA21 protects against intervertebral disc degeneration through targeting miR-200c and X linked inhibitor-of-apoptosis protein
by Cheng, Xiaofei and Zhang, Liang and Zhang, Kai and Zhang, Guoying and Hu, Ying and Sun, Xiaojiang and Zhao, Changqing and Li, Hua and Li, Yan Michael and Zhao, Jie
Annals of the Rheumatic Diseases, ISSN 0003-4967, 05/2018, Volume 77, Issue 5, pp. 770 - 779
ObjectivesCircular RNAs (circRNAs) have been proven to function as competing endogenous RNAs to interact with microRNAs (miRNAs) and influence the expression... 
cytokines | inflammation | TNF-alpha | low back pain | osteoarthritis | INTERLEUKIN-1 | CYTOKINES | NUCLEUS PULPOSUS CELLS | INFLAMMASOME ACTIVATION | DEGRADATION | DEATH | IL-1-BETA | TNF-ALPHA | RHEUMATOLOGY | CANCER | EXPRESSION | Vacuolar Proton-Translocating ATPases - genetics | Nucleus Pulposus - metabolism | Humans | Cell Survival - genetics | Extracellular Matrix - metabolism | Rats | Apoptosis - genetics | Signal Transduction - genetics | X-Linked Inhibitor of Apoptosis Protein - genetics | RNA - genetics | Animals | MicroRNAs - genetics | Intervertebral Disc Degeneration - genetics | Animal models | Back pain | Cytokines | MiRNA | XIAP protein | Inflammation | Arthritis | mRNA | Nucleus pulposus | Kinases | Intervertebral discs | Gene expression | Nuclei | Proteins | Rodents | Collagen | Circular RNA | Extracellular matrix | TNF inhibitors | Tumor necrosis factor-TNF | Degeneration | Binding sites | Apoptosis | Index Medicus | 2311 | Basic and Translational Research | 1506 | tnf-alpha
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6. Full Text Characterization of Crohn disease in X-linked inhibitor of apoptosis–deficient male patients and female symptomatic carriers
by Aguilar, Claire, MD and Lenoir, Christelle, MS and Lambert, Nathalie, AS and Bègue, Bernadette, MS and Brousse, Nicole, MD and Canioni, Danielle, MD and Berrebi, Dominique, MD, PhD and Roy, Maryline, MS and Gérart, Stéphane, ME, PhD and Chapel, Helen, MA, MD and Schwerd, Tobias, MD and Siproudhis, Laurent, MD, PhD and Schäppi, Michela, MD, PhD and Al-Ahmari, Ali, MD and Mori, Masaaki, MD, PhD and Yamaide, Akiko, MD and Galicier, Lionel, MD and Neven, Bénédicte, MD, PhD and Routes, John, MD and Uhlig, Holm H., MD, PhD and Koletzko, Sibylle, MD and Patel, Smita, MD, PhD and Kanegane, Hirokazu, MD, PhD and Picard, Capucine, MD, PhD and Fischer, Alain, MD, PhD and Bensussan, Nadine Cerf, MD, PhD and Ruemmele, Frank, MD, PhD and Hugot, Jean-Pierre, MD, PhD and Latour, Sylvain, PhD
Journal of Allergy and Clinical Immunology, The, ISSN 0091-6749, 2014, Volume 134, Issue 5, pp. 1131 - 1141.e9
Background Crohn disease is an inflammatory bowel disease (IBD) with a complex mode of inheritance. Although nucleotide binding and oligomerization domain... 
Allergy and Immunology | Inflammatory bowel disease | Crohn disease | monocytes | NOD receptors | X-linked inhibitor of apoptosis immunodeficiency | PATHWAYS | VARIANTS | SUSCEPTIBILITY | NOD2 | AUTOPHAGY | IMMUNOLOGY | INFLAMMATORY-BOWEL-DISEASE | ALLERGY | MUTATION | XIAP DEFICIENCY | ASSOCIATION | IMMUNODEFICIENCY | Crohn Disease - genetics | Humans | Child, Preschool | Infant | Male | Nod2 Signaling Adaptor Protein - genetics | Adult | Female | Genetic Diseases, X-Linked - genetics | Child | Cytokines - genetics | Cytokines - blood | Genetic Diseases, X-Linked - blood | Chromosomes, Human, X - genetics | Lymphoproliferative Disorders - genetics | Lymphoproliferative Disorders - pathology | Lymphoproliferative Disorders - blood | X-Linked Inhibitor of Apoptosis Protein - genetics | Hemizygote | Nod2 Signaling Adaptor Protein - metabolism | Crohn Disease - pathology | Crohn Disease - blood | Adolescent | Age of Onset | Genetic Diseases, X-Linked - pathology | Heterozygote | Chromosomes, Human, X - metabolism | Cohort Studies | Women | Oligomers | Crohn's disease | Health aspects | Risk factors | Apoptosis | Proteins | Signal transduction | Cytokines | Biopsy | Boys | Mutation | Patients | Age | Immune system | Index Medicus | Abridged Index Medicus
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7. Full Text X-linked inhibitor of apoptosis (XIAP) deficiency: The spectrum of presenting manifestations beyond hemophagocytic lymphohistiocytosis
by Speckmann, C and Lehmberg, K and Albert, M.H and Damgaard, R.B and Fritsch, M and Gyrd-Hansen, M and Rensing-Ehl, A and Vraetz, T and Grimbacher, B and Salzer, U and Fuchs, I and Ufheil, H and Belohradsky, B.H and Hassan, A and Cale, C.M and Elawad, M and Strahm, B and Schibli, S and Lauten, M and Kohl, M and Meerpohl, J.J and Rodeck, B and Kolb, R and Eberl, W and Soerensen, J and von Bernuth, H and Lorenz, M and Schwarz, K and zur Stadt, U and Ehl, S
Clinical Immunology, ISSN 1521-6616, 2013, Volume 149, Issue 1, pp. 133 - 141
Abstract X-linked inhibitor of apoptosis (XIAP) deficiency caused by mutations in BIRC4 was initially described in patients with X-linked lymphoproliferative... 
Allergy and Immunology | Inflammatory bowel disease | BIRC4 | Hemophagocytic lymphohistiocytosis | XIAP | Hematopoietic stem cell transplantation | IL10 | GENE | INFLAMMATION | DISEASE | MUTATIONS | IMMUNOLOGY | X-Linked Inhibitor of Apoptosis Protein - deficiency | Humans | Child, Preschool | Genotype | Male | X-Linked Inhibitor of Apoptosis Protein - immunology | X-Linked Inhibitor of Apoptosis Protein - genetics | Young Adult | Phenotype | Adolescent | Immunologic Deficiency Syndromes - genetics | Adult | Mutation | Immunologic Deficiency Syndromes - immunology | Lymphohistiocytosis, Hemophagocytic - genetics | Child | Lymphohistiocytosis, Hemophagocytic - immunology | Natural Killer T-Cells - immunology | Gastrointestinal diseases | Analysis | Apoptosis | Index Medicus
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8. Full Text The Ubiquitin Ligase XIAP Recruits LUBAC for NOD2 Signaling in Inflammation and Innate Immunity
by Damgaard, Rune Busk and Nachbur, Ueli and Yabal, Monica and Wong, Wendy Wei-Lynn and Fiil, Berthe Katrine and Kastirr, Mischa and Rieser, Eva and Rickard, James Arthur and Bankovacki, Aleksandra and Peschel, Christian and Ruland, Juergen and Bekker-Jensen, Simon and Mailand, Niels and Kaufmann, Thomas and Strasser, Andreas and Walczak, Henning and Silke, John and Jost, Philipp J and Gyrd-Hansen, Mads
Molecular Cell, ISSN 1097-2765, 06/2012, Volume 46, Issue 6, pp. 746 - 758
Nucleotide-binding and oligomerization domain (NOD)-like receptors constitute a first line of defense against invading bacteria. X-linked Inhibitor of... 
APOPTOSIS | ACTIVATION | SHARPIN | BIOCHEMISTRY & MOLECULAR BIOLOGY | DYSREGULATION | INFECTION | PROTEINS | POLYUBIQUITINATION | INHIBITOR | NF-KAPPA-B | DEFICIENCY | CELL BIOLOGY | Signal Transduction | Mice, Inbred C57BL | Ubiquitin - metabolism | Ubiquitin-Protein Ligases - metabolism | Mice, Transgenic | Nod2 Signaling Adaptor Protein - genetics | Inflammation - immunology | Immunity, Innate | Receptor-Interacting Protein Serine-Threonine Kinase 2 - genetics | X-Linked Inhibitor of Apoptosis Protein - genetics | Receptor-Interacting Protein Serine-Threonine Kinase 2 - metabolism | Animals | Nod2 Signaling Adaptor Protein - metabolism | X-Linked Inhibitor of Apoptosis Protein - metabolism | Female | Mice | Ubiquitin-Protein Ligases - genetics | Ubiquitin | Oligomers | Hepatitis | Bacterial infections | Ligases | Immunodeficiency | Bacteria | Inflammation | Universities and colleges | Apoptosis | Index Medicus
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9. Full Text The Akt/Mcl-1 pathway plays a prominent role in mediating antiapoptotic signals downstream of the B-cell receptor in chronic lymphocytic leukemia B cells
by Longo, Pablo G and Laurenti, Luca and Gobessi, Stefania and Sica, Simona and Leone, Giuseppe and Efremov, Dimitar G
Blood, ISSN 0006-4971, 01/2008, Volume 111, Issue 2, pp. 846 - 855
Sustained engagement of the B-cell receptor (BCR) increases apoptosis resistance in chronic lymphocytic leukemia (CLL) B cells, whereas transient stimulation... 
ACTIVATION | AKT PHOSPHORYLATION | BCL-2/BAX RATIO | X-LINKED INHIBITOR | MCL-1 | ANTI-IGM | SURVIVAL SIGNALS | CD38 EXPRESSION | HEMATOLOGY | APOPTOSIS PROTEIN | GENE MUTATION STATUS | RNA, Small Interfering - genetics | Humans | bcl-X Protein - genetics | Cell Survival - genetics | Male | Neoplasm Proteins - antagonists & inhibitors | Phosphatidylinositol 3-Kinases - metabolism | Extracellular Signal-Regulated MAP Kinases - metabolism | Leukemia, Lymphocytic, Chronic, B-Cell - genetics | Receptors, Antigen, B-Cell - metabolism | Neoplasm Proteins - metabolism | Extracellular Signal-Regulated MAP Kinases - genetics | Proto-Oncogene Proteins c-akt - genetics | Proto-Oncogene Proteins c-bcl-2 - metabolism | MAP Kinase Signaling System - genetics | Female | B-Lymphocytes - pathology | Neoplasm Proteins - genetics | Proto-Oncogene Proteins c-akt - metabolism | MAP Kinase Kinase 2 - genetics | B-Lymphocytes - metabolism | Cell Survival - drug effects | RNA, Small Interfering - pharmacology | MAP Kinase Kinase 2 - metabolism | Down-Regulation - drug effects | Down-Regulation - genetics | Leukemia, Lymphocytic, Chronic, B-Cell - pathology | X-Linked Inhibitor of Apoptosis Protein - genetics | Phosphatidylinositol 3-Kinases - genetics | MAP Kinase Signaling System - drug effects | Leukemia, Lymphocytic, Chronic, B-Cell - metabolism | Myeloid Cell Leukemia Sequence 1 Protein | X-Linked Inhibitor of Apoptosis Protein - metabolism | Cell Line, Tumor | Proto-Oncogene Proteins c-bcl-2 - antagonists & inhibitors | Receptors, Antigen, B-Cell - genetics | bcl-X Protein - metabolism | Proto-Oncogene Proteins c-bcl-2 - genetics | Apoptosis | Index Medicus | Abridged Index Medicus
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10. Full Text XIAP Mediates NOD Signaling via Interaction with RIP2
by Andreas Krieg and Ricardo G. Correa and Jason B. Garrison and Gaëlle Le Negrate and Kate Welsh and Ziwei Huang and Wolfram T. Knoefel and John C. Reed and Erkki Ruoslahti
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 8/2009, Volume 106, Issue 34, pp. 14524 - 14529
NOD1 and NOD2 are members of the NOD-like receptor (NLR) protein family that are involved in sensing the presence of pathogens and are a component of the... 
Proteins | HEK293 cells | HCT116 cells | Plasmids | Cell lines | Antibodies | Reporter genes | Ligands | Immunoblotting | Apoptosis | CYTOCHROME-C | NEGATIVE BACTERIAL-INFECTION | ACTIVATION | HOST RECOGNITION | MULTIDISCIPLINARY SCIENCES | ALPHA-DEPENDENT APOPTOSIS | IAP | CELL-SURVIVAL | PROTEIN XIAP | NF-KAPPA-B | DROSOPHILA INHIBITOR | RNA, Small Interfering - genetics | Immunoprecipitation | Luciferases - metabolism | Humans | NF-kappa B - metabolism | Nod2 Signaling Adaptor Protein - genetics | Green Fluorescent Proteins - genetics | Receptor-Interacting Protein Serine-Threonine Kinase 2 - genetics | Nod1 Signaling Adaptor Protein - metabolism | Recombinant Fusion Proteins - metabolism | Luciferases - genetics | Receptor-Interacting Protein Serine-Threonine Kinase 2 - metabolism | Transfection | Interleukin-8 - metabolism | Cell Line | Green Fluorescent Proteins - metabolism | Gene Expression | Enzyme-Linked Immunosorbent Assay | Signal Transduction | HCT116 Cells | Reverse Transcriptase Polymerase Chain Reaction | X-Linked Inhibitor of Apoptosis Protein - genetics | NF-kappa B - genetics | Nod2 Signaling Adaptor Protein - metabolism | X-Linked Inhibitor of Apoptosis Protein - metabolism | Cell Line, Tumor | Protein Binding | Recombinant Fusion Proteins - genetics | Mutation | Nod1 Signaling Adaptor Protein - genetics | Research | Immunity | Bacteria | Peptides | Kinases | Immune system | Index Medicus | Biological Sciences
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11. Full Text Overcoming resistance to TRAIL-induced apoptosis in solid tumor cells by simultaneously targeting death receptors, c-FLIP and IAPs
by HUANG, YING and YANG, XIANG and XU, TIANRUI and KONG, QINGHONG and ZHANG, YAPING and SHEN, YUEHAI and WEI, YUNLIN and WANG, GUANLIN and CHANG, KWEN-JEN
International Journal of Oncology, ISSN 1019-6439, 07/2016, Volume 49, Issue 1, pp. 153 - 163
The discovery of the TRAIL protein and its death receptors DR4/5 changed the horizon of cancer research because TRAIL specifically kills cancer cells. However,... 
IAPs | apoptosis | cancer therapy | TRAIL | c-FLIP | drug combination | C-FLIP | Drug combination | Cancer therapy | Apoptosis | LIGAND TRAIL | CASPASE-8 EXPRESSION | ANTITUMOR-ACTIVITY | NEUROBLASTOMA-CELLS | CANCER-THERAPY | DRUG-INDUCED APOPTOSIS | GENE | ONCOLOGY | ANTICANCER THERAPY | IN-VIVO | SENSITIZES | Antineoplastic Combined Chemotherapy Protocols - administration & dosage | Benzhydryl Compounds - administration & dosage | Apoptosis - drug effects | CASP8 and FADD-Like Apoptosis Regulating Protein - genetics | CASP8 and FADD-Like Apoptosis Regulating Protein - antagonists & inhibitors | Humans | Benzofurans - administration & dosage | CASP8 and FADD-Like Apoptosis Regulating Protein - biosynthesis | TNF-Related Apoptosis-Inducing Ligand - therapeutic use | X-Linked Inhibitor of Apoptosis Protein - genetics | Neoplasms - drug therapy | X-Linked Inhibitor of Apoptosis Protein - antagonists & inhibitors | Drug Resistance, Neoplasm - genetics | Neoplasms - genetics | Signal Transduction - drug effects | Cell Line, Tumor | Azocines - administration & dosage | Gene Expression Regulation, Neoplastic - drug effects | Neoplasms - pathology | RNA, Small Interfering - administration & dosage | TNF-Related Apoptosis-Inducing Ligand - genetics | X-Linked Inhibitor of Apoptosis Protein - biosynthesis | Transcription factors | Care and treatment | Innovations | Genetic aspects | Drug resistance | Gene expression | Health aspects | Cancer | Studies | Proteins | Immunoglobulins | Chemotherapy | Brain cancer | Rodents | Cytotoxicity | Kinases | Cancer therapies | Tumors
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