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index medicus (136) 136
animals (124) 124
mice (109) 109
immunology (102) 102
xid mice (64) 64
humans (56) 56
x-linked agammaglobulinemia (50) 50
b-lymphocytes - immunology (49) 49
protein-tyrosine kinases - genetics (45) 45
male (42) 42
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brutons tyrosine kinase (36) 36
xid (34) 34
mice, inbred cba (32) 32
mice, inbred balb c (28) 28
btk (26) 26
mice, inbred c57bl (26) 26
expression (25) 25
signal transduction (25) 25
mutation (24) 24
b-cells (23) 23
biochemistry & molecular biology (23) 23
immunodeficient xid mice (23) 23
mice, mutant strains (23) 23
b-lymphocyte subsets - immunology (21) 21
protein-tyrosine kinases - metabolism (20) 20
x chromosome (20) 20
agammaglobulinaemia tyrosine kinase (19) 19
agammaglobulinemia - genetics (19) 19
b-lymphocytes - cytology (19) 19
cell biology (18) 18
xid-like immunodeficiency (18) 18
bruton's tyrosine kinase (17) 17
genetic linkage (17) 17
protein-tyrosine kinases - physiology (17) 17
abridged index medicus (16) 16
b cells (16) 16
lymphocytes (16) 16
mouse (16) 16
protein-tyrosine kinases - deficiency (16) 16
b-lymphocytes - enzymology (15) 15
b-lymphocytes - physiology (15) 15
deficient mice (15) 15
immunodeficiency (15) 15
immunologic deficiency syndromes - immunology (15) 15
mice, knockout (15) 15
signal-transduction (15) 15
activation (14) 14
cell differentiation (14) 14
lymphocyte activation (14) 14
receptors, antigen, b-cell - physiology (13) 13
bone-marrow (12) 12
cells, cultured (12) 12
immunologic deficiency syndromes - genetics (12) 12
molecular sequence data (12) 12
t-lymphocytes - immunology (12) 12
b-1 cells (11) 11
mice, transgenic (11) 11
phosphoinositide 3-kinase (11) 11
phospholipase c-gamma-2 (11) 11
spleen - immunology (11) 11
agammaglobulinemia - immunology (10) 10
disease models, animal (10) 10
factor-kappa-b (10) 10
immune-response (10) 10
tyrosine kinase (10) 10
x-linked immunodeficiency (10) 10
autoimmunity (9) 9
b-lymphocytes - metabolism (9) 9
gene expression (9) 9
medicine, research & experimental (9) 9
nf-kappa-b (9) 9
phosphatidylinositol 3-kinase (9) 9
receptor (9) 9
signal transduction - immunology (9) 9
agammaglobulinemia (8) 8
amino acid sequence (8) 8
antigen receptor (8) 8
base sequence (8) 8
cba-n mice (8) 8
cell differentiation - immunology (8) 8
child (8) 8
flow cytometry (8) 8
hemic and lymphatic diseases (8) 8
in-vivo (8) 8
inflammation (8) 8
ph domain (8) 8
phosphorylation (8) 8
protein-tyrosine kinases - immunology (8) 8
receptors, antigen, b-cell - metabolism (8) 8
t-cell (8) 8
t-cells (8) 8
tyrosine (8) 8
x chromosome - genetics (8) 8
adoptive transfer (7) 7
agammaglobulinemia - enzymology (7) 7
allergy and immunology (7) 7
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antigens (7) 7
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Journal Article
Journal Article
Journal Article
Journal Article
Journal of Immunology, ISSN 0022-1767, 06/2004, Volume 172, Issue 11, pp. 6615 - 6625
Phosphoinositide 3-kinase activation is important for lymphocyte proliferation and survival. Disrupting the gene that encodes the major phosphoinositide... 
BRUTONS TYROSINE KINASE | IMPAIRED B-CELL | PHOSPHATIDYLINOSITOL 3-KINASE | MEDIATED ACTIVATION | DEFICIENT | DEATH | IMMUNOLOGY | EXPRESSION | P85-ALPHA | XID-LIKE IMMUNODEFICIENCY | LYMPHOCYTES
Journal Article
The Journal of Immunology, ISSN 0022-1767, 03/2002, Volume 168, Issue 6, pp. 2695 - 2703
textabstractBruton's tyrosine kinase (Btk) is a cytoplasmic signaling molecule that is crucial for precursor (pre-B) cell differentiation in humans. In this... 
XID MUTATION | BONE-MARROW | LIGHT-CHAIN | X-LINKED AGAMMAGLOBULINEMIA | V(D)J RECOMBINATION | LYMPHOCYTES-B | IMMUNOLOGY | MU-HEAVY-CHAIN | EXPRESSION | IMMUNODEFICIENCY | ANTIGEN | Mice, Knockout - genetics | Mice, Knockout - immunology | Cell Cycle - genetics | Agammaglobulinemia - immunology | Immunoglobulin Heavy Chains - biosynthesis | Agammaglobulinemia - genetics | Bone Marrow Cells - enzymology | Hematopoietic Stem Cells - pathology | Interleukin-7 - physiology | Protein-Tyrosine Kinases - deficiency | Cell Differentiation - genetics | Agammaglobulinemia - pathology | Hematopoietic Stem Cells - immunology | Protein-Tyrosine Kinases - genetics | Cell Division - immunology | Bone Marrow Cells - immunology | Cell Cycle - immunology | B-Lymphocyte Subsets - immunology | Protein-Tyrosine Kinases - biosynthesis | Antigens, Differentiation, B-Lymphocyte - genetics | Cell Division - genetics | Cytoplasm - enzymology | B-Lymphocyte Subsets - pathology | Mice, Inbred C57BL | Bone Marrow Cells - pathology | Cells, Cultured | Immunophenotyping | B-Lymphocyte Subsets - enzymology | Cell Differentiation - immunology | Immunoglobulin mu-Chains - genetics | Animals | Cytoplasm - immunology | Agammaglobulinaemia Tyrosine Kinase | Antigens, Differentiation, B-Lymphocyte - biosynthesis | Immunoglobulin mu-Chains - biosynthesis | Mice | Hematopoietic Stem Cells - enzymology | Immunoglobulin Heavy Chains - genetics | CD25 antigen | Bruton's tyrosine kinase | CD2 antigen | Index Medicus | Abridged Index Medicus
Journal Article
Journal Article
European Journal of Immunology, ISSN 0014-2980, 2002, Volume 32, Issue 7, pp. 1939 - 1946
We have investigated the role of B cells in myelin oligodendrocyte glycoprotein (MOG)-induced experimental autoimmune encephalomyelitis (EAE) using B... 
B lymphocyte | Experimental autoimmune encephalomyelitis | Xid | Myelin oligodendrocyte glycoprotein | μMT
Journal Article
Journal Article