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Experimental Cell Research, ISSN 0014-4827, 01/2018, Volume 362, Issue 2, pp. 450 - 460
X-ray repair cross-complementing group 4 (XRCC4), a repair protein for DNA double-strand breaks, is cleaved by caspases during apoptosis. In this study, we... 
XRCC4 | CAD | SRSF1 | Apoptosis | ICAD | SRPK1 | SPLICING FACTORS | CANCER-CELLS | STRAND BREAK REPAIR | SR PROTEIN | ICAD-S | PHOSPHORYLATION | XRCC4 PROTEIN | FRAGMENTATION | MAMMALIAN-CELLS | CELL BIOLOGY | ONCOLOGY | LIGASE IV | Proteins | RNA | Cells
Journal Article
Journal of Veterinary Medical Science, ISSN 0916-7250, 2016
Various chemotherapies and radiation therapies are useful for killing cancer cells mainly by inducing DNA double-strand breaks (DSBs). Uncovering the molecular... 
XRCC4 | DNA damage | canine | companion animal
Journal Article
by Jaafar, L and Li, ZT and Li, SY and Dynan, WS
NUCLEIC ACIDS RESEARCH, ISSN 0305-1048, 02/2017, Volume 45, Issue 4, pp. 1848 - 1859
A complex of two related mammalian proteins, SFPQ and NONO, promotes DNA double-strand break repair via the canonical nonhomologous end joining (c-NHEJ)... 
COMPLEX | PSF | PROTEIN | XRCC4 | BIOCHEMISTRY & MOLECULAR BIOLOGY | LIGATION | P54(NRB) | SPLICING-FACTOR | LIGASE-IV | BINDING
Journal Article
Journal of Allergy and Clinical Immunology, The, ISSN 0091-6749, 2015, Volume 136, Issue 4, pp. 1007 - 1017
Journal Article
NATURE COMMUNICATIONS, ISSN 2041-1723, 09/2018, Volume 9
PAXX is a recently identified component of the nonhomologous end joining (NHEJ) DNA repair pathway. The molecular mechanisms of PAXX action remain largely... 
XLF | XRCC4 | CHROMATIN | INTERACTS | MULTIDISCIPLINARY SCIENCES | ESCHERICHIA-COLI | POL-MU | ENDS | DEPENDENT PROTEIN-KINASE | DOUBLE-STRAND BREAKS
Journal Article
Asian Pacific Journal of Cancer Prevention, ISSN 1513-7368, 2013, Volume 14, Issue 1, pp. 449 - 452
Polymorphisms in DNA repair genes have been shown to influence DNA repair processes and to modify cancer susceptibility. Here we conducted a case-control study... 
Glioma | DNA repair gene | Meningiomas | Polymorphism | XRCC4 GENE | POPULATION | meningiomas | VARIANTS | ONCOLOGY | CANCER SUSCEPTIBILITY | glioma | polymorphism | ASSOCIATION | RADIATION
Journal Article
Translational Cancer Research, ISSN 2218-676X, 06/2013, Volume 2, Issue 3, pp. 130 - 143
DNA double-stranded breaks (DSB) are among the most dangerous forms of DNA damage. Unrepaired DSBs results in cells undergoing apoptosis or senescence whereas... 
DNA-Ligase IV | DNA-PKcs | Ku70/80 | XLF | XRCC4 | Non-homologous end-joining | DNA double strand breaks | non-homologous end-joining | ONCOLOGY | Ku70
Journal Article