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Hypertension, ISSN 0194-911X, 05/2013, Volume 61, Issue 5, pp. 1091 - 1102
Journal Article
Journal Article
Advances in experimental medicine and biology, ISSN 0065-2598, 2019, Volume 1127, p. 59
Inhibition of xanthine oxidoreductase (XOR) has proven beneficial in a plethora of inflammatory disease processes due to a net reduction in pro-inflammatory... 
Nitrates - chemistry | Oxidants - chemistry | Xanthine Dehydrogenase - antagonists & inhibitors | Humans | Inflammation | Fatty Acids - pharmacology
Journal Article
PLoS ONE, ISSN 1932-6203, 05/2015, Volume 10, Issue 5, p. e0124150
Ectopic calcification is a driving force for a variety of diseases, including kidney stones and atherosclerosis, but initiating factors remain largely unknown.... 
MALPIGHIAN TUBULES | NANOBACTERIA | XANTHINE OXIDOREDUCTASE | MEDICAL-MANAGEMENT | MULTIDISCIPLINARY SCIENCES | CALCIUM | GROWTH | RISK | CALCIFICATION | PLAQUE | INSIGHTS | Xanthine Dehydrogenase - metabolism | RNA, Small Interfering - genetics | Cation Transport Proteins - antagonists & inhibitors | Kidney - pathology | Xanthine Dehydrogenase - antagonists & inhibitors | Zinc - metabolism | Humans | Xanthine Dehydrogenase - genetics | Drosophila Proteins - metabolism | Drosophila melanogaster - genetics | Malpighian Tubules - chemistry | Drosophila melanogaster - metabolism | Kidney - metabolism | Cation Transport Proteins - metabolism | Dietary Proteins - pharmacology | Cation Transport Proteins - genetics | Malpighian Tubules - drug effects | Drosophila Proteins - antagonists & inhibitors | Disease Models, Animal | X-Ray Absorption Spectroscopy | Gene Expression | Kidney - drug effects | Chelating Agents - pharmacology | Kidney Calculi - metabolism | Kidney Calculi - pathology | Ethylenediamines - pharmacology | Animals | Dogs | Allopurinol - pharmacology | Drosophila Proteins - genetics | Malpighian Tubules - pathology | Kidney Calculi - genetics | Kidney Calculi - prevention & control | RNA, Small Interfering - metabolism | Care and treatment | Drosophila | Fossilization | Diagnosis | Research | Risk factors | Zinc | Kidney stones | Calcification (ectopic) | Dehydrogenases | Disease | Xanthine dehydrogenase | Biology | Hydroxyapatite | Stone | Urology | Etiology | Mineralization | Rodents | Atherosclerosis | Aging | Physiology | Inhibition | Plaques | Spectroscopy | Kidneys | Pharmacology | Xanthine | Metabolism | Zinc transporter | Diet | Insects | Arteriosclerosis | Calcification | Lithiasis | Trace elements | Mutation | Transporter | Kidney transplantation
Journal Article
Free Radical Biology and Medicine, ISSN 0891-5849, 10/2016, Volume 99, pp. 472 - 484
Xanthine oxidoreductase (XOR) is generally known as the final enzyme in purine metabolism and as a source of reactive oxygen species (ROS). In addition, this... 
Hypertension | Oxidative stress | Endothelial nitric oxide synthase | Reactive oxygen species | Nitrate | Febuxostat | Nitric oxide | Xanthine oxidoreductase | Xanthine oxidase | Superoxide | Nitrite | Uric acid | NADPH OXIDASE | METABOLIC SYNDROME | OXIDASE INHIBITOR FEBUXOSTAT | BIOCHEMISTRY & MOLECULAR BIOLOGY | BLOOD-PRESSURE | REACTIVE SPECIES GENERATION | INDUCED HYPERTENSION | SYNTHASE ACTIVITY | ENDOCRINOLOGY & METABOLISM | DIETARY INORGANIC NITRATE | Xanthine Dehydrogenase - metabolism | Xanthine Dehydrogenase - antagonists & inhibitors | Xanthine Dehydrogenase - genetics | Nitrates - pharmacology | Male | Nitric Oxide Synthase Type III - deficiency | Febuxostat - pharmacology | Nitric Oxide Synthase Type II - antagonists & inhibitors | Nitric Oxide Synthase Type I - antagonists & inhibitors | Nitrites - blood | Superoxides - metabolism | Blood Pressure - drug effects | NG-Nitroarginine Methyl Ester - pharmacology | Nitrates - blood | Nitric Oxide - blood | Oxidation-Reduction | Signal Transduction | Nitric Oxide Synthase Type II - deficiency | Enzyme Inhibitors - pharmacology | Gene Expression Regulation | Nitric Oxide Synthase Type III - genetics | Nitrites - pharmacology | Mice, Knockout | Nitric Oxide Synthase Type I - deficiency | Nitric Oxide Synthase Type III - antagonists & inhibitors | Animals | Nitric Oxide Synthase Type II - genetics | Mice | Nitric Oxide Synthase Type I - genetics | Oxidases | Iron compounds | Homeostasis | Biological Sciences | Medical and Health Sciences | Medicin och hälsovetenskap | Klinisk medicin | Cell Biology | Clinical Medicine | Naturvetenskap | Endokrinologi och diabetes | Biologiska vetenskaper | Natural Sciences | Cellbiologi | Endocrinology and Diabetes
Journal Article
Circulation Research, ISSN 0009-7330, 10/2008, Volume 103, Issue 9, pp. 957 - 964
Reduction of nitrite (NO2) provides a major source of nitric oxide (NO) in the circulation, especially in hypoxemic conditions. Our previous studies suggest... 
Blood vessels | Hypoxia | Cardiovascular research | Nitric oxide | HEMOGLOBIN | hypoxia | nitric oxide | OXIDATIVE STRESS | CARDIAC & CARDIOVASCULAR SYSTEMS | blood vessels | INDUCED VASODILATION | cardiovascular research | ISCHEMIA-REPERFUSION INJURY | IN-VIVO | S-NITROSOTHIOLS | MEDIATED DECOMPOSITION | PERIPHERAL VASCULAR DISEASE | RED-BLOOD-CELLS | REDUCES NITRITE | HEMATOLOGY | Xanthine Dehydrogenase - metabolism | Rats, Wistar | Xanthine Dehydrogenase - antagonists & inhibitors | Humans | Nitrites - metabolism | Male | omega-N-Methylarginine - pharmacology | Fluorometry | Cell Hypoxia | Nitrite Reductases - antagonists & inhibitors | Nitrites - blood | Erythrocytes - enzymology | Nitric Oxide Synthase Type III - metabolism | Aorta - enzymology | NG-Nitroarginine Methyl Ester - pharmacology | Nitric Oxide - blood | Oxidation-Reduction | Cells, Cultured | Enzyme Inhibitors - pharmacology | Rats | Xanthine Dehydrogenase - blood | Erythrocytes - drug effects | Nitric Oxide Synthase Type III - antagonists & inhibitors | Xanthine - metabolism | Nitric Oxide Synthase Type III - blood | Animals | Allopurinol - pharmacology | Nitric Oxide - metabolism | Endothelial Cells - enzymology | Arginine - metabolism | Endothelial Cells - drug effects | Hydrogen-Ion Concentration | Nitric Oxide Synthase Type II - metabolism | Nitrite Reductases - metabolism
Journal Article
Journal of Pharmacology and Experimental Therapeutics, ISSN 0022-3565, 01/2011, Volume 336, Issue 1, pp. 95 - 103
Journal Article
British Journal of Pharmacology, ISSN 0007-1188, 07/2015, Volume 172, Issue 13, pp. 3341 - 3352
Journal Article
Arteriosclerosis, Thrombosis, and Vascular Biology, ISSN 1079-5642, 02/2012, Volume 32, Issue 2, pp. 291 - 298
Journal Article