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1. Full Text Effects of xanthine oxidase inhibition in hyperuricemic heart failure patients: The xanthine oxidase inhibition for hyperuricemic heart failure patients (EXACT-HF) study
by Givertz, Michael M and Anstrom, Kevin J and Redfield, Margaret M and Deswal, Anita and Haddad, Haissam and Butler, Javed and Tang, W.H. Wilson and Dunlap, Mark E and LeWinter, Martin M and Mann, Douglas L and Felker, G. Michael and O'Connor, Christopher M and Goldsmith, Steven R and Ofili, Elizabeth O and Saltzberg, Mitchell T and Margulies, Kenneth B and Cappola, Thomas P and Konstam, Marvin A and Semigran, Marc J and McNulty, Steven E and Lee, Kerry L and Shah, Monica R and Hernandez, Adrian F and NHLBI Heart Failure Clinical Res and NHLBI Heart Failure Clinical Research Network
Circulation (New York, N.Y.), ISSN 0009-7322, 2015, Volume 131, Issue 20, pp. 1763 - 1771
Heart failure | Clinical trial | Xanthine oxidase | Allopurinol | Cardiac & Cardiovascular Systems | Peripheral Vascular Disease | Life Sciences & Biomedicine | Cardiovascular System & Cardiology | Science & Technology | Oxidative Stress | Humans | Middle Aged | Gout - drug therapy | Hospitalization - statistics & numerical data | Male | Heart Failure - blood | Exercise Test | Endpoint Determination | Ultrasonography | Female | Surveys and Questionnaires | Heart Failure - diagnostic imaging | Hyperuricemia - complications | Xanthine Oxidase - antagonists & inhibitors | Heart Failure - complications | Double-Blind Method | Treatment Outcome | Biomarkers - blood | Hyperuricemia - drug therapy | Stroke Volume | Gout Suppressants - therapeutic use | Allopurinol - therapeutic use | Allopurinol - adverse effects | Exercise Tolerance | Quality of Life | Diuretics - therapeutic use | Aged | Index Medicus | Abridged Index Medicus
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2. Full Text Nitric oxide production from nitrite occurs primarily in tissues not in the blood: Critical role of xanthine oxidase and aldehyde oxidase
by Li, Haitao and Cui, Hongmei and Kundu, Tapan Kumar and Alzawahra, Wael and Zweier, Jay L
The Journal of biological chemistry, ISSN 0021-9258, 06/2008, Volume 283, Issue 26, pp. 17855 - 17863
Life Sciences & Biomedicine | Biochemistry & Molecular Biology | Science & Technology | Electron Spin Resonance Spectroscopy | Liver - metabolism | Nitrites - metabolism | Rats | Substrate Specificity | Male | Rats, Sprague-Dawley | Xanthine Oxidase - chemistry | Gene Expression Regulation, Enzymologic | Animals | Aldehyde Oxidase - chemistry | Models, Biological | Myocardium - metabolism | Nitric Oxide - metabolism | Hydrogen-Ion Concentration | Index Medicus | Enzyme Catalysis and Regulation
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3. Full Text Utilization of quercetin and quercetin glycosides from onion (Allium cepa L.) solid waste as an antioxidant, urease and xanthine oxidase inhibitors
by Nile, Shivraj Hariram and Nile, Arti Shivraj and Keum, Young Soo and Sharma, Kavita
Food chemistry, ISSN 0308-8146, 11/2017, Volume 235, pp. 119 - 126
Antioxidants | Solid waste | Xanthine oxidase | Urease | Onion | HPLC | Physical Sciences | Chemistry | Life Sciences & Biomedicine | Chemistry, Applied | Nutrition & Dietetics | Food Science & Technology | Science & Technology | Urease - analysis | Plant Extracts | Quercetin - analysis | Onions - chemistry | Glycosides | Urease - antagonists & inhibitors | Xanthine Oxidase - analysis | Xanthine Oxidase - antagonists & inhibitors | Solid Waste | Oxidases | Enzymes | Iron compounds | Refuse and refuse disposal | Hydrolases | Xanthine | Care and treatment | Flavones | Bioflavonoids | Gout | Esters | Purines | Flavonoids | Analysis | High performance liquid chromatography | Index Medicus
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4. Full Text Angiotensin II Induces Endothelial Xanthine Oxidase Activation: Role for Endothelial Dysfunction in Patients With Coronary Disease
by Landmesser, Ulf and Spiekermann, Stephan and Preuss, Christoph and Sorrentino, Sajoscha and Fischer, Dieter and Manes, Costantina and Mueller, Maja and Drexler, Helmut
Arteriosclerosis, thrombosis, and vascular biology, ISSN 1079-5642, 04/2007, Volume 27, Issue 4, pp. 943 - 948
Xanthine oxidase | Free radicals | Angiotensin II | Coronary disease | Endothelium | Peripheral Vascular Disease | Life Sciences & Biomedicine | Hematology | Cardiovascular System & Cardiology | Science & Technology | Cardiology. Vascular system | Heart | Sarcoidosis. Granulomatous diseases of unproved etiology. Connective tissue diseases. Elastic tissue diseases. Vasculitis | Diseases of the peripheral vessels. Diseases of the vena cava. Miscellaneous | Atherosclerosis (general aspects, experimental research) | Biological and medical sciences | Medical sciences | Coronary heart disease | Blood and lymphatic vessels | Humans | Middle Aged | NADPH Oxidases - metabolism | Coronary Disease - physiopathology | Male | Endothelium, Vascular - enzymology | Angiotensin II Type 1 Receptor Blockers - pharmacology | Cattle | Oxypurinol - pharmacology | Superoxides - metabolism | Female | Xanthine Oxidase - antagonists & inhibitors | Coronary Circulation | Xanthine Oxidase - metabolism | Angiotensin II - pharmacology | Endothelial Cells - metabolism | Cells, Cultured | Endothelium, Vascular - physiopathology | Enzyme Inhibitors - pharmacology | Losartan - pharmacology | Enzyme Activation - drug effects | Animals | Coronary Disease - enzymology | Allopurinol - pharmacology | Aged | Vasodilation - drug effects | Endothelial Cells - drug effects | Index Medicus
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5. Full Text Cross talk between mitochondria and NADPH oxidases
by Dikalov, Sergey
Free radical biology & medicine, ISSN 0891-5849, 10/2011, Volume 51, Issue 7, pp. 1289 - 1301
Mitochondria | Free radicals | Mitochondria-targeted antioxidant | NADPH oxidase | Feed-forward regulation | Superoxide | ATP-sensitive potassium channel | Biochemistry & Molecular Biology | Endocrinology & Metabolism | Life Sciences & Biomedicine | Science & Technology | Reactive Oxygen Species - metabolism | Humans | NADPH Oxidases - metabolism | Hypertension - drug therapy | Neurodegenerative Diseases - drug therapy | Piperidines - pharmacology | Oxidation-Reduction - drug effects | Organophosphorus Compounds - pharmacology | Nitric Oxide Synthase Type III - metabolism | Superoxide Dismutase - metabolism | Rabbits | Xanthine Oxidase - metabolism | Angiotensin II - pharmacology | Atherosclerosis - drug therapy | Signal Transduction | Atherosclerosis - physiopathology | Diabetes Mellitus - drug therapy | Diabetes Mellitus - metabolism | Rats | Mitochondria - metabolism | Antioxidants - pharmacology | Mitochondria - drug effects | Neurodegenerative Diseases - metabolism | Atherosclerosis - metabolism | Hypertension - physiopathology | Hypertension - metabolism | Reactive Oxygen Species - antagonists & inhibitors | Animals | Neurodegenerative Diseases - physiopathology | Diabetes Mellitus - physiopathology | Mice | Oxidative Stress - drug effects | Aging - metabolism | Antioxidants | Oxidases | Mitochondrial DNA | Atherosclerosis | Index Medicus
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6. Full Text Coumarin derivatives as promising xanthine oxidase inhibitors
by Fais, Antonella and Era, Benedetta and Asthana, Shailendra and Sogos, Valeria and Medda, Rosaria and Santana, Lourdes and Uriarte, Eugenio and Matos, Maria João and Delogu, Francesco and Kumar, Amit
International journal of biological macromolecules, ISSN 0141-8130, 12/2018, Volume 120, Issue Pt A, pp. 1286 - 1293
Coumarin derivatives | Molecular docking | Xanthine oxidase inhibition | Biochemistry & Molecular Biology | Physical Sciences | Chemistry | Life Sciences & Biomedicine | Chemistry, Applied | Polymer Science | Science & Technology | Catalytic Domain | Enzyme Inhibitors - chemistry | Coumarins - chemistry | Molecular Docking Simulation | Molecular Structure | Structure-Activity Relationship | Allopurinol - chemistry | Xanthine Oxidase - antagonists & inhibitors | Oxidases | Purines | Iron compounds | Drug discovery | Analysis | Index Medicus
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7. Full Text Synthesis, characterization and xanthine oxidase inhibition of Cu(II)–chrysin complex
by Lin, Suyun and Zeng, Li and Zhang, Guowen and Liao, Yijing and Gong, Deming
Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy, ISSN 1386-1425, 05/2017, Volume 178, pp. 71 - 78
Molecular simulation | Xanthine oxidase | Inhibition | Cu(II)-chrysin complex | Spectroscopy | Technology | Science & Technology | Copper - pharmacology | Enzyme Inhibitors - pharmacology | Spectrometry, Fluorescence | Enzyme Inhibitors - chemical synthesis | Xanthine Oxidase - chemistry | Animals | Copper - chemistry | Flavonoids - chemical synthesis | Cattle | Enzyme Inhibitors - chemistry | Protein Conformation | Flavonoids - pharmacology | Molecular Docking Simulation | Kinetics | Binding Sites | Circular Dichroism | Flavonoids - chemistry | Xanthine Oxidase - antagonists & inhibitors | Oxidases | Iron compounds | Molybdenum compounds | Hydrogen | Analysis | Nuclear magnetic resonance spectroscopy | Uric acid | Mass spectrometry
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8. Full Text Uric acid and xanthine oxidase in heart failure — Emerging data and therapeutic implications
by Doehner, Wolfram and Jankowska, Ewa A and Springer, Jochen and Lainscak, Mitja and Anker, Stefan D
International journal of cardiology, ISSN 0167-5273, 2015, Volume 213, pp. 15 - 19
Cardiovascular | Sarcopenia | Cachexia | Muscle | MCAO model | Ischemic stroke | Xanthine Oxidase - metabolism | Prognosis | Reactive Oxygen Species - metabolism | Uric Acid - metabolism | Heart Failure - enzymology | Humans | Risk Factors | Heart Failure - metabolism | Heart Failure - pathology | Oxidases | Heart failure | Iron compounds | Molybdenum compounds | Uric acid | Health aspects | Risk factors | Stroke (Disease) | Mortality | Index Medicus
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