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Veterinary Microbiology, ISSN 0378-1135, 11/2019, Volume 238, p. 108431
The infection by porcine reproductive and respiratory syndrome virus (PRRSV) has a severe impact on the world swine industry. However, commercially available... 
Xanthohumol | PRRSV | Antiviral activity
Journal Article
Free Radical Biology and Medicine, ISSN 0891-5849, 11/2015, Volume 88, Issue Pt B, pp. 417 - 426
In light of the emerging interplay between redox and metabolic signaling pathways we investigated the potential cross talk between nuclear factor E2-related... 
Xanthohumol | Nrf2 | ER stress | AMPK | HO-1 | PERK | LKB1 | MEF | PHOSPHORYLATION | BIOCHEMISTRY & MOLECULAR BIOLOGY | KINASE | MECHANISMS | ENERGY SENSOR | CELL DEFENSE PATHWAY | ENDOTHELIAL-CELLS | ENDOCRINOLOGY & METABOLISM | NRF2-MEDIATED INDUCTION | HEME OXYGENASE-1 | STRESS | AMP-Activated Protein Kinases - metabolism | Heme Oxygenase-1 - metabolism | Reactive Oxygen Species - metabolism | Oxidation-Reduction | Oxidative Stress - physiology | Propiophenones - pharmacology | Mitochondria - metabolism | Mitochondria - drug effects | Receptor Cross-Talk - physiology | Blotting, Western | Animals | Flow Cytometry | Fibroblasts - drug effects | NF-E2-Related Factor 2 - metabolism | Signal Transduction - physiology | Flavonoids - pharmacology | Membrane Proteins - metabolism | Mice | Real-Time Polymerase Chain Reaction | Unfolded Protein Response - physiology | Fibroblasts - metabolism | RNA | Glycogen | Synthesis | ACC, acetyl-CoA carboxylase | CHO, Chinese hamster ovary | GSH, glutathione (reduced) | OCR, oxygen consumption rate | HO-1, heme oxygenase 1 | CaMKK, calcium calmodulin-dependent kinase kinase | Maf, small musculoaponeurotic fibrosarcoma | PERK, protein kinase RNA-like endoplasmic reticulum kinase | Xn, xanthohumol | Hrd1, synoviolin | TAK, transforming growth factor β-activated kinase | UPR, unfolded protein response | Hrd1 (HMG-CoA reductase degradation)-ubiquitin ligase | MEF, mouse embryonic fibroblasts | βTrcP1, β-transducin-repeat containing protein 1 | mTOR, mammalian target of rapamycin | ROS, reactive oxygen species | LKB1, liver kinase B1 | Keap1, Kelch-like ECH-associated protein | GSSG, oxidized glutathione | ARE, antioxidant response element | WT, wild type | GSK3β, glycogen synthase kinase 3β | Nrf2, nuclear factor E2-related factor 2 | AMPK, AMP-activated kinase | DCF, dichlorofluorescein | NADPH, nicotinamide adenine dinucleotide phosphate | DMSO, dimethyl sulfoxide | ER, endoplasmic reticulum | FCS, fetal calf serum
Journal Article
Asian Pacific Journal of Cancer Prevention, ISSN 1513-7368, 2012, Volume 13, Issue 1, pp. 47 - 51
Journal Article
Journal of Chromatography B, ISSN 1570-0232, 09/2018, Volume 1095, pp. 39 - 49
Journal Article
Chinese Journal of Cancer Prevention and Treatment, ISSN 1673-5269, 07/2017, Volume 24, Issue 14, pp. 960 - 965
Journal Article
by Lu and Geng and Zhang and Miao and Liu
Antioxidants, ISSN 2076-3921, 09/2019, Volume 8, Issue 9, p. 402
BCR-ABL oncoprotein drives the initiation, promotion, and progression of chronic myelogenous leukemia (CML). Tyrosine kinase inhibitors are the first choice... 
degradation | autophagy | K562 | xanthohumol | BCR-ABL | caspase
Journal Article
Analytical Chemistry, ISSN 0003-2700, 03/2018, Volume 90, Issue 5, pp. 3156 - 3164
METLIN originated as a database to characterize known metabolites and has since expanded into a technology platform for the identification of known and unknown... 
CHEMISTRY, ANALYTICAL | TANDEM MASS-SPECTRA | POWERFUL TOOL | DATABASE | CELL EXTRACT | METABOLITE IDENTIFICATION | UNTARGETED METABOLOMICS | XANTHOHUMOL | CANCER | SPECTROMETRY | WORKFLOW | Usage | Chemistry, Analytic | Research | Mass spectrometry | Isotopes
Journal Article
Oncotarget, ISSN 1949-2553, 2018, Volume 9, Issue 1, pp. 866 - 880
Xanthohumol (XN), a prenylated chalcone isolated from the hop plant, has been reported to exhibit multiple biological functions including anti-inflammation.... 
NF-κB | Colitis | IKKβ | Xanthohumol | DSS
Journal Article
Innovative Food Science and Emerging Technologies, ISSN 1466-8564, 10/2012, Volume 16, pp. 54 - 60
Hop ( ) is one of the richest natural sources of a prenylfalvonoids such as xanthohumol (XN), desmetylxanthohumol (DMX), isoxanthohumol (IX) or... 
Prenylflavonoids | Pressurized hot water extraction (PHWE) | Isoxanthohumol (IX) | Anti-inflammatory | Xanthohumol (XN) | APOPTOSIS | HUMULUS-LUPULUS L | PHYTOESTROGEN 8-PRENYLNARINGENIN | FOOD SCIENCE & TECHNOLOGY | XANTHOHUMOL | BEER
Journal Article
Molecular nutrition & food research, ISSN 1613-4125, 2/2014, Volume 58, Issue 2, pp. 248 - 255
Journal Article
Journal of Natural Products, ISSN 0163-3864, 12/2017, Volume 80, Issue 12, pp. 3081 - 3092
Twenty compounds, including 14 new a-acid derivatives, a new chromone, and five known compounds, were identified from the pistillate inflorescence of Humulus... 
CHEMISTRY, MEDICINAL | CIRCULAR-DICHROISM | FUNGUS | ABSOLUTE-CONFIGURATION | PHARMACOLOGY & PHARMACY | XANTHOHUMOL | AGENTS | HOPS | PRENYLATED CHALCONE | L | PLANT SCIENCES
Journal Article
Journal of Functional Foods, ISSN 1756-4646, 06/2019, Volume 57, pp. 95 - 102
The present work aims to characterize and investigate the anti-inflammatory activity of hop extracts (cv. Cascade) in an model of gastric inflammation. The... 
Hop | Gastric inflammation | AGS cells | Humulus lupulus L | Xanthohumol | IL-8
Journal Article
Chemical Communications, ISSN 1359-7345, 2016, Volume 52, Issue 81, pp. 12060 - 12063
The first red emission off-on probe, TRFS-red, for thioredoxin reductase was reported. Compared to the previous green emission probe TRFS-green,... 
STRESS-MEDIATED APOPTOSIS | OXIDATIVE STRESS | PROTECTION | ON FLUORESCENT-PROBE | ENZYMES | XANTHOHUMOL | PC12 CELLS | INHIBITOR | DERIVATIVES | CHEMISTRY, MULTIDISCIPLINARY | LIVING CELLS | Emission | Reductases | Enzymes | Emissions control | Selectivity | Mammals
Journal Article
Journal Article
by Sun, H and Wang, D and Song, XT and Zhang, YZ and Ding, WN and Peng, XL and Zhang, XT and Li, YS and Ma, Y and Wang, RL and Yu, P
JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY, ISSN 0021-8561, 03/2017, Volume 65, Issue 8, pp. 1574 - 1581
Inhibition of alpha-glucosidase and alpha-amylase decreases postprandial blood glucose levels and delays glucose absorption, making it a treatment strategy for... 
VITRO | PRENYLFLAVONOIDS | HUMULUS-LUPULUS L | FOOD SCIENCE & TECHNOLOGY | prenylnaringenin | PRENYLATED FLAVONOIDS | XANTHOHUMOL | MOLECULAR DOCKING | prenylchalconaringenin | ANTIOXIDATIVE ACTIVITY | BEER HOPS | docking | alpha-glucosidase | alpha-amylase | METABOLISM | AGRICULTURE, MULTIDISCIPLINARY | TETRACYCLIC OXINDOLE DERIVATIVES | CHEMISTRY, APPLIED | diabetes
Journal Article
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 05/2018, Volume 115, Issue 22, p. E5223
Xanthohumol (XN) and demethylxanthohumol (DMX) are specialized prenylated chalconoids with multiple pharmaceutical applications that accumulate to high levels... 
Binding | Plants (botany) | Yeast | Naringenin | Xanthohumol | Hops | Biosynthesis | Fatty acids | Chalcone synthase | Proteins | Flavonoids | Plant growth | Protein folding | Chalcone isomerase | Docking | Trichomes
Journal Article
Food and Feed Research, ISSN 2217-5369, 2019, Volume 46, Issue 1, pp. 23 - 35
Recently, the consciousness of consumers about the food impact on health is continuously increasing. In response to that, nowadays there is a worldwide... 
specialty beer | xanthohumol | Ganoderma | brewed beverage | herbs | probiotics
Journal Article
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