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1. Metabolism of drugs and other xenobiotics
by Anzenbacher, Pavel and Zanger, Ulrich M
2012, ISBN 9783527329038, xxix, 724
Toxicology | Biotransformation (Metabolism) | Xenobiotics | Metabolism | Medical | Drugs
Book
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2. Xenobiotica
Xenobiotica, ISSN 0049-8254, 1971
Drugs | Periodicals | Metabolism | Physiological effect | Food additives | Chemicals
Journal
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3. Full Text Dietary polyunsaturated fatty acids and heme iron induce oxidative stress biomarkers and a cancer promoting environment in the colon of rats
by Guéraud, Françoise and Taché, Sylviane and Steghens, Jean-Paul and Milkovic, Lidija and Borovic-Sunjic, Suzana and Zarkovic, Neven and Gaultier, Eric and Naud, Nathalie and Héliès-Toussaint, Cécile and Pierre, Fabrice and Priymenko, Nathalie
Free radical biology & medicine, ISSN 0891-5849, 06/2015, Volume 83, pp. 192 - 200
4-Hydroxynonenal | Polyunsaturated fatty acids | Colorectal cancer | Lipid peroxidation | Biomarkers | Heme iron | Malondialdehyde | Biochemistry & Molecular Biology | Endocrinology & Metabolism | Life Sciences & Biomedicine | Science & Technology | Biomarkers - urine | Heme - metabolism | Reactive Oxygen Species - metabolism | Oxidative Stress | Diet - adverse effects | Antioxidants - metabolism | Rats, Inbred F344 | Colon - drug effects | Tumor Microenvironment | Colonic Neoplasms - metabolism | Lipid Peroxidation - drug effects | Female | Rectal Neoplasms - pathology | Tumor Cells, Cultured | Rectal Neoplasms - etiology | Colonic Neoplasms - etiology | Malondialdehyde - metabolism | Colon - pathology | Rats | Thiobarbituric Acid Reactive Substances - metabolism | Iron - metabolism | Colon - metabolism | Animals | Colonic Neoplasms - pathology | Fatty Acids, Unsaturated - adverse effects | Mice | Rectal Neoplasms - metabolism | Oxidative stress | Unsaturated fatty acids | Metabolites | Heme | Xenobiotics | Biological markers | Meat | Index Medicus | Life Sciences
Journal Article
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4. Biodegradation
1990
Biodegradation | Periodicals | Refuse and refuse disposal | Déchets | Biodégradation | Élimination
Newspaper
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5. Full Text Coordinate transcriptional regulation of bile acid homeostasis and drug metabolism
by Eloranta, Jyrki J and Kullak-Ublick, Gerd A
Archives of biochemistry and biophysics, ISSN 0003-9861, 2005, Volume 433, Issue 2, pp. 397 - 412
Coactivators and corepressors | Gene regulation | Drug metabolism | Xenobiotics | Nuclear receptors | Bile acids and salts | Hepatocyte nuclear factors | Steroid 12-alpha-Hydroxylase - metabolism | Steroid Hydroxylases - metabolism | Histone Acetyltransferases | Receptors, Steroid - metabolism | Receptors, Virus - metabolism | Humans | Cytochrome P-450 Enzyme System - metabolism | Homeostasis | Receptors, Glucocorticoid - metabolism | Coxsackie and Adenovirus Receptor-Like Membrane Protein | Phosphoproteins - metabolism | DNA-Binding Proteins - metabolism | Transcription, Genetic | Heat-Shock Proteins - metabolism | Bile Acids and Salts - metabolism | Receptors, Calcitriol - metabolism | Forecasting | Transcription Factors - metabolism | Feedback, Physiological | Pharmaceutical Preparations - metabolism | Animals | Cholesterol 7-alpha-Hydroxylase - metabolism | Models, Biological | Nuclear Receptor Coactivator 1 | Ligands | Trans-Activators - metabolism | Cholestanetriol 26-Monooxygenase | Hepatocyte Nuclear Factor 4 | Multidrug Resistance-Associated Proteins - metabolism | Receptors, Cytoplasmic and Nuclear - metabolism | Index Medicus
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6. Full Text The SLC22 family with transporters of organic cations, anions and zwitterions
by Koepsell, Hermann
Molecular aspects of medicine, ISSN 0098-2997, 04/2013, Volume 34, Issue 2-3, pp. 413 - 435
Cation transporter | Drug transporter | Anion transporter | Urate transporter | SLC22 | Drug excretion | Biochemistry & Molecular Biology | Life Sciences & Biomedicine | Medicine, Research & Experimental | Science & Technology | Research & Experimental Medicine | Multigene Family - genetics | Nucleotides, Cyclic - metabolism | Uric Acid - metabolism | Organic Cation Transport Proteins - metabolism | Humans | Liver - metabolism | Neurotransmitter Agents - metabolism | Models, Molecular | Ion Pumps - genetics | Organic Cation Transporter 1 - metabolism | Carnitine - metabolism | Ion Pumps - metabolism | Organic Cation Transporter 2 | Brain - metabolism | Kidney - metabolism | Absorption | Protein Conformation | Intestine, Small - metabolism | Ion Pumps - physiology | Ketoglutaric Acids - metabolism | Prostaglandins - metabolism | Levocarnitine | Xenobiotics | Cells | Membrane proteins | Index Medicus
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7. Full Text AMPK: A nutrient and energy sensor that maintains energy homeostasis
by Hardie, D. Grahame and Ross, Fiona A and Hawley, Simon A
Nature reviews. Molecular cell biology, ISSN 1471-0072, 04/2012, Volume 13, Issue 4, pp. 251 - 262
Life Sciences & Biomedicine | Science & Technology | Cell Biology | Mammals - metabolism | AMP-Activated Protein Kinases - metabolism | Glucose Transporter Type 4 - metabolism | Oxidative Stress | Humans | Circadian Rhythm - physiology | Mitochondria - metabolism | Xenobiotics - pharmacology | AMP-Activated Protein Kinases - chemistry | Animals | Hypothalamus - metabolism | Adenosine Triphosphate - metabolism | Glucose - metabolism | Appetite - physiology | Adenosine Diphosphate - metabolism | Energy Metabolism - physiology | Energy Metabolism - drug effects | Physiological aspects | Research | Adenylic acid | Neurons | Protein kinases | Adenosine triphosphate | Index Medicus
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8. Full Text An in vitro approach to detect metabolite toxicity due to CYP3A4-dependent bioactivation of xenobiotics
by Vignati, Luisella and Turlizzi, Elisa and Monaci, Sonia and Grossi, Pietro and Kanter, Ruben de and Monshouwer, Mario
Toxicology (Amsterdam), ISSN 0300-483X, 2005, Volume 216, Issue 2, pp. 154 - 167
Reactive metabolites | Cytotoxicity | Metabolism-mediated toxicity | CYP3A4 | In vitro screening | Adverse drug reactions (ADRs) | Pharmacology & Pharmacy | Toxicology | Life Sciences & Biomedicine | Science & Technology | Biological and medical sciences | Medical sciences | Microsomes - metabolism | Thiazoles - metabolism | Cytochrome P-450 Enzyme Inhibitors | Cytochrome P-450 CYP3A | Coculture Techniques | Humans | Thiazolidinediones - toxicity | Cytochrome P-450 Enzyme System - metabolism | Isoniazid - toxicity | Xenobiotics - toxicity | Chromans - metabolism | Flutamide - metabolism | Triazolam - toxicity | Microsomes - drug effects | Triazolam - metabolism | Adenosine Triphosphate - metabolism | Carbamazepine - toxicity | Toxicity Tests - methods | Xenobiotics - metabolism | Cell Culture Techniques | Cell Survival - drug effects | Albendazole - toxicity | Tamoxifen - toxicity | Dapsone - metabolism | Dapsone - toxicity | Cell Line, Tumor | Glutathione - chemistry | Troglitazone | Buthionine Sulfoximine - pharmacology | Quinidine - toxicity | Amitriptyline - toxicity | Glutathione - metabolism | Flutamide - toxicity | Substrate Specificity | Piperazines - metabolism | Piperazines - toxicity | Ochratoxins - metabolism | Xenobiotics - chemistry | Tetrazolium Salts - metabolism | Carbamazepine - metabolism | Quinidine - metabolism | Tamoxifen - metabolism | Amitriptyline - metabolism | Glutathione - antagonists & inhibitors | Enzyme Activation - drug effects | Thiazolidinediones - metabolism | Ochratoxins - toxicity | Thiazoles - toxicity | Animals | Albendazole - metabolism | Chromans - toxicity | Isoniazid - metabolism | Phosphates | Metabolites | Ketoconazole | Cytochrome P-450 | Control systems | Xenobiotics | Glutathione | Index Medicus
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