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1. Metabolism of drugs and other xenobiotics
by Anzenbacher, Pavel and Zanger, Ulrich M
2012, ISBN 9783527329038, xxix, 724
A practice-oriented desktop reference for medical professionals, toxicologists and pharmaceutical researchers, this handbook provides systematic coverage of... 
Toxicology | Biotransformation (Metabolism) | Xenobiotics | Metabolism | Medical | Drugs
Book
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2. Xenobiotica
Xenobiotica, ISSN 0049-8254, 1971
Drugs | Periodicals | Metabolism | Physiological effect | Food additives | Chemicals
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3. Human drug metabolism
: an introduction
by Coleman, Michael D
2010, 2nd ed., ISBN 9780470742167, xiv, 346
Human Drug Metabolism, An Introduction, Second Edition provides an accessible introduction to the subject and will be particularly invaluable to those who... 
Drugs | Psychological aspects | toxicity | Pharmaceutical Preparations | Xenobiotics | Metabolism | Physiological effect
Book
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4. Full Text Dietary polyunsaturated fatty acids and heme iron induce oxidative stress biomarkers and a cancer promoting environment in the colon of rats
by Guéraud, Françoise and Taché, Sylviane and Steghens, Jean-Paul and Milkovic, Lidija and Borovic-Sunjic, Suzana and Zarkovic, Neven and Gaultier, Eric and Naud, Nathalie and Héliès-Toussaint, Cécile and Pierre, Fabrice and Priymenko, Nathalie
Free Radical Biology and Medicine, ISSN 0891-5849, 06/2015, Volume 83, pp. 192 - 200
The end products of polyunsaturated fatty acid (PUFA) peroxidation, such as malondialdehyde (MDA), 4-hydroxynonenal (HNE), and isoprostanes (8-iso-PGF ), are... 
4-Hydroxynonenal | Polyunsaturated fatty acids | Colorectal cancer | Lipid peroxidation | Biomarkers | Heme iron | Malondialdehyde | LIPID-PEROXIDATION | COLORECTAL CARCINOGENESIS | HUMAN PLASMA | SOYBEAN OIL | TOXIC ALDEHYDE | BIOCHEMISTRY & MOLECULAR BIOLOGY | MERCAPTURIC ACID | URINARY METABOLITE | ANIMAL-TISSUES | IN-VIVO | ENDOCRINOLOGY & METABOLISM | BEEF MEAT | Biomarkers - urine | Heme - metabolism | Reactive Oxygen Species - metabolism | Oxidative Stress | Diet - adverse effects | Antioxidants - metabolism | Rats, Inbred F344 | Colon - drug effects | Tumor Microenvironment | Colonic Neoplasms - metabolism | Lipid Peroxidation - drug effects | Female | Rectal Neoplasms - pathology | Tumor Cells, Cultured | Rectal Neoplasms - etiology | Colonic Neoplasms - etiology | Malondialdehyde - metabolism | Colon - pathology | Rats | Thiobarbituric Acid Reactive Substances - metabolism | Iron - metabolism | Colon - metabolism | Animals | Colonic Neoplasms - pathology | Fatty Acids, Unsaturated - adverse effects | Mice | Rectal Neoplasms - metabolism | Oxidative stress | Unsaturated fatty acids | Metabolites | Heme | Xenobiotics | Biological markers | Meat | Index Medicus | Life Sciences
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5. Hydrolysis in drug and prodrug metabolism
: chemistry, biochemistry, and enzymology
by Testa, Bernard and Mayer, Joachim M
2003, ISBN 9783906390253, xx, 780
Drugs | Hydrolysis | Médicaments | Xénobiotiques | Hydrolyse | Xenobiotics | Metabolism | Métabolisme
Book
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6. Pesticide metabolism
: extrapolation from animals to man
by Miyamoto, J. (Junshi) and International Union of Pure and Applied Chemistry
1988, ISBN 9780632022564, vi, 120
Metabolism | Physiological effect | Pesticides
Book
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7. Full Text Coordinate transcriptional regulation of bile acid homeostasis and drug metabolism
by Eloranta, Jyrki J and Kullak-Ublick, Gerd A
Archives of Biochemistry and Biophysics, ISSN 0003-9861, 2005, Volume 433, Issue 2, pp. 397 - 412
Drugs and bile acids are taken up into hepatocytes by specialized transport proteins localized at the basolateral membrane, e.g., organic anion transporting... 
Coactivators and corepressors | Gene regulation | Drug metabolism | Xenobiotics | Nuclear receptors | Bile acids and salts | Hepatocyte nuclear factors | SMALL HETERODIMER PARTNER | xenobiotics | NEGATIVE FEEDBACK-REGULATION | SALT EXPORT PUMP | BIOCHEMISTRY & MOLECULAR BIOLOGY | VITAMIN-D-RECEPTOR | hepatocyte nuclear factors | coactivators and corepressors | ORPHAN NUCLEAR RECEPTOR | nuclear receptors | BIOPHYSICS | gene regulation | CONSTITUTIVE ANDROSTANE RECEPTOR | drug metabolism | bile acids and salts | FARNESOID-X-RECEPTOR | CHOLESTEROL 7-ALPHA-HYDROXYLASE GENE | STEROL 27-HYDROXYLASE GENE | FAMILIAL INTRAHEPATIC CHOLESTASIS | Steroid 12-alpha-Hydroxylase - metabolism | Steroid Hydroxylases - metabolism | Histone Acetyltransferases | Receptors, Steroid - metabolism | Receptors, Virus - metabolism | Humans | Cytochrome P-450 Enzyme System - metabolism | Homeostasis | Receptors, Glucocorticoid - metabolism | Coxsackie and Adenovirus Receptor-Like Membrane Protein | Phosphoproteins - metabolism | DNA-Binding Proteins - metabolism | Transcription, Genetic | Heat-Shock Proteins - metabolism | Bile Acids and Salts - metabolism | Receptors, Calcitriol - metabolism | Forecasting | Transcription Factors - metabolism | Feedback, Physiological | Pharmaceutical Preparations - metabolism | Animals | Cholesterol 7-alpha-Hydroxylase - metabolism | Models, Biological | Nuclear Receptor Coactivator 1 | Ligands | Trans-Activators - metabolism | Cholestanetriol 26-Monooxygenase | Hepatocyte Nuclear Factor 4 | Multidrug Resistance-Associated Proteins - metabolism | Receptors, Cytoplasmic and Nuclear - metabolism
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8. Full Text The SLC22 family with transporters of organic cations, anions and zwitterions
by Koepsell, Hermann
Molecular Aspects of Medicine, ISSN 0098-2997, 04/2013, Volume 34, Issue 2-3, pp. 413 - 435
The SLC22 family contains 13 functionally characterized human plasma membrane proteins each with 12 predicted α-helical transmembrane domains. The family... 
Cation transporter | Drug transporter | Anion transporter | Urate transporter | SLC22 | Drug excretion | MEDICINE, RESEARCH & EXPERIMENTAL | CARNITINE TRANSPORTER | MESSENGER-RNA EXPRESSION | BIOCHEMISTRY & MOLECULAR BIOLOGY | DRUG UPTAKE TRANSPORTERS | BLOOD-BRAIN-BARRIER | KIDNEY-SPECIFIC EXPRESSION | GENETIC-VARIATION | OCTN1 SLC22A4 | CATION/CARNITINE TRANSPORTERS | MOLECULAR-CLONING | URIC-ACID | Multigene Family - genetics | Nucleotides, Cyclic - metabolism | Uric Acid - metabolism | Organic Cation Transport Proteins - metabolism | Humans | Liver - metabolism | Neurotransmitter Agents - metabolism | Models, Molecular | Ion Pumps - genetics | Organic Cation Transporter 1 - metabolism | Carnitine - metabolism | Ion Pumps - metabolism | Organic Cation Transporter 2 | Brain - metabolism | Kidney - metabolism | Absorption | Protein Conformation | Intestine, Small - metabolism | Ion Pumps - physiology | Ketoglutaric Acids - metabolism | Prostaglandins - metabolism | Levocarnitine | Xenobiotics | Cells | Membrane proteins | Index Medicus
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9. Full Text Metabolic Hydrolysis of Aromatic Amides in Selected Rat, Minipig, and Human in Vitro Systems
by Bradshaw, Peter R and Wilson, Ian D and Gill, Rachel Upcott and Butler, Philip J and Dilworth, Clive and Athersuch, Toby J
Scientific Reports, ISSN 2045-2322, 12/2018, Volume 8, Issue 1, pp. 2405 - 8
The release of aromatic amines from drugs and other xenobiotics resulting from the hydrolysis of metabolically labile amide bonds presents a safety risk... 
ACTIVATION | PRILOCAINE | PHARMACOKINETICS | CARBOXYLESTERASE | MULTIDISCIPLINARY SCIENCES | FLUTAMIDE | ARYLACETAMIDE DEACETYLASE | HUMAN-LIVER | DRUG-METABOLISM | Acetanilides - metabolism | Nitriles - metabolism | Acetaminophen - metabolism | Humans | Microsomes, Liver - metabolism | Anilides - metabolism | Rats | Male | Niclosamide - metabolism | Hepatocytes - metabolism | Carboxylesterase - metabolism | Rats, Sprague-Dawley | Subcellular Fractions - metabolism | Flutamide - metabolism | Hydrolysis | Lidocaine - metabolism | Animals | Swine | Swine, Miniature | Tosyl Compounds - metabolism | Amides - metabolism | Propanil - metabolism | Primary Cell Culture | Prilocaine - metabolism | Animal models | Amines | Hydrolase | Serine | Liver | Genotoxicity | Amides | Serine hydrolase | Metabolism | Carboxylesterase | Microsomes | Ames test | Metabolites | Hepatocytes | Rodents | Mutagenicity | Xenobiotics
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10. Cytochromes P450
: role in the metabolism and toxicity of drugs and other xenobiotics
by Ioannides, Costas
2008, Issues in toxicology, ISBN 0854042741, xviii, 521
During half a century, cytochrome P450 in its original uniqueness as an optically "wrong" cytochrome has attracted many investigators, who have contributed to... 
Cytochrome P-450 -- Physiological effect | Xenobiotics -- Metabolism | Biology, life sciences | Cytochrome P-450 | Chemistry | Organic | SCIENCE | Xenobiotics | Metabolism
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11. Full Text AMPK: A nutrient and energy sensor that maintains energy homeostasis
by Hardie, D. Grahame and Ross, Fiona A and Hawley, Simon A
Nature Reviews Molecular Cell Biology, ISSN 1471-0072, 04/2012, Volume 13, Issue 4, pp. 251 - 262
AMP-activated protein kinase (AMPK) is a crucial cellular energy sensor. Once activated by falling energy status, it promotes ATP production by increasing the... 
SKELETAL-MUSCLE | STRUCTURAL INSIGHT | ACTIVATED PROTEIN-KINASE | FATTY-ACID OXIDATION | 14-3-3 BINDING | UPSTREAM KINASE | ACETYL-COA CARBOXYLASE | DIETARY RESTRICTION | GLUCOSE-UPTAKE | DIRECT PHOSPHORYLATION | CELL BIOLOGY | Mammals - metabolism | AMP-Activated Protein Kinases - metabolism | Glucose Transporter Type 4 - metabolism | Oxidative Stress | Humans | Circadian Rhythm - physiology | Mitochondria - metabolism | Xenobiotics - pharmacology | AMP-Activated Protein Kinases - chemistry | Animals | Hypothalamus - metabolism | Adenosine Triphosphate - metabolism | Glucose - metabolism | Appetite - physiology | Adenosine Diphosphate - metabolism | Energy Metabolism - physiology | Energy Metabolism - drug effects | Physiological aspects | Research | Adenylic acid | Neurons | Protein kinases | Adenosine triphosphate
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