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2015, 2015, ISBN 1482221349, xix, 530
Pharmacokinetics and Toxicokinetics provides an overview of pharmacokinetics and toxicokinetics in a comprehensible, interrelated, and applied manner. It... 
Drugs | Pharmacokinetics | Toxicology | Other branches of medicine | Mathematical Modeling | Pharmaceutical Science
Book
2005, ISBN 0471478148, xix, 420
Presents an overview of the underlying principles of PBPK model development. This book provides a compendium of PBPK modeling information, including historical... 
Chemistry | SCIENCE | Industrial & Technical | Pharmacokinetics | Xenobiotics | Toxicology
Book
Methods in Molecular Biology, ISSN 1064-3745, 2016, Volume 1425, pp. 37 - 62
Pharmacokinetics is the study of the fate of xenobiotics in a living organism. Physiologically based pharmacokinetic (PBPK) models provide realistic... 
PBPK | R software | Numerical integration | 1,3-Butadiene | Monte carlo simulations | Butadienes - pharmacology | Computational Biology - methods | Animals | Models, Biological | Humans | Butadienes - pharmacokinetics | Software | Monte Carlo Method | Life Sciences | Toxicology
Journal Article
Journal of Pharmacology and Experimental Therapeutics, ISSN 0022-3565, 06/2010, Volume 333, Issue 3, pp. 788 - 796
Journal Article
PLoS ONE, ISSN 1932-6203, 01/2014, Volume 9, Issue 1, p. e82331
Brain cancer is a devastating disease affecting many people worldwide. Effective treatment with chemotherapeutics is limited due to the presence of the... 
MALIGNANT GLIOMA | CELLS | TRANSPORT | MULTIDISCIPLINARY SCIENCES | BARRIER | METASTASES | ADRIAMYCIN | BIODISTRIBUTION | MODEL | CHEMOTHERAPY | PACLITAXEL | Doxorubicin - blood | Glutathione - pharmacokinetics | Doxorubicin - therapeutic use | Capillaries - pathology | Humans | Brain Neoplasms - pathology | Body Weight - drug effects | Polyethylene Glycols - therapeutic use | Drug Delivery Systems | Brain - blood supply | Glutathione - pharmacology | Time Factors | Doxorubicin - analogs & derivatives | Female | Polyethylene Glycols - pharmacology | Glutathione - therapeutic use | Tissue Distribution - drug effects | Glutathione - analogs & derivatives | Endothelial Cells - metabolism | Polyethylene Glycols - pharmacokinetics | Treatment Outcome | Brain Neoplasms - drug therapy | Doxorubicin - pharmacokinetics | Brain - drug effects | Animals | Mice, Nude | Glioblastoma - pathology | Survival Analysis | Brain - pathology | Cell Proliferation - drug effects | Mice | Brain Neoplasms - ultrastructure | Endothelial Cells - pathology | Glioblastoma - drug therapy | Doxorubicin - pharmacology | Glutathione - blood | Drugs | Plasma physics | Drug delivery systems | Anthracyclines | Thiols | Gliomas | Brain tumors | Drug therapy | Cancer | Vehicles | Nuclear medicine | Bioluminescence | Neurosciences | Brain cancer | Glioblastoma | Drug delivery | Metastasis | Cancer therapies | Doxorubicin | Antioxidants | Blood-brain barrier | Inhibition | Xenobiotics | Glutathione | Medical treatment | Pharmacology | Breast cancer | Disease control | Endothelial cells | Studies | Chemotherapy | Brain research | Diffusion barriers | Medical prognosis | Pharmacokinetics | Tumors
Journal Article
Environmental Health Perspectives, ISSN 0091-6765, 4/2011, Volume 119, Issue 4, pp. 422 - 430
Journal Article
Journal Article
Xenobiotica, ISSN 0049-8254, 10/2013, Volume 43, Issue 10, pp. 920 - 931
Journal Article
Journal Article