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1. Full Text Physiologically based pharmacokinetic modeling
: science and applications
by Reddy, Micaela B
2005, ISBN 0471478148, 443
Pharmacokinetics | Xenobiotics | Toxicology | Chemistry | SCIENCE | Industrial & Technical
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2. Pharmacokinetics and toxicokinetics
by Boroujerdi, Mehdi
2015, ISBN 1482221349, xix, 530
Drugs | Pharmacokinetics | Toxicology | Mathematical Modeling | Pharmaceutical Science
Book
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3. Kinetic analysis of the cooperation of P-glycoprotein (P-gp/Abcb1) and breast cancer resistance protein (Bcrp/Abcg2) in limiting the brain and testis penetration of erlotinib, flavopiridol, and mitoxantrone
by Kodaira, Hiroshi and Kusuhara, Hiroyuki and Ushiki, Junko and Fuse, Eiichi and Sugiyama, Yuichi
The Journal of pharmacology and experimental therapeutics, ISSN 0022-3565, 06/2010, Volume 333, Issue 3, pp. 788 - 796
Life Sciences & Biomedicine | Pharmacology & Pharmacy | Science & Technology | ATP Binding Cassette Transporter, Sub-Family G, Member 2 | Erlotinib Hydrochloride | Testis - metabolism | ATP-Binding Cassette, Sub-Family B, Member 1 - metabolism | Quinazolines - pharmacokinetics | Male | Neoplasm Proteins - metabolism | Brain - metabolism | Tissue Distribution | Dantrolene - pharmacokinetics | ATP-Binding Cassette Transporters - genetics | Quinidine - pharmacokinetics | ATP-Binding Cassette Transporters - metabolism | Piperidines - pharmacokinetics | Antineoplastic Agents - pharmacokinetics | Xenobiotics - metabolism | Neoplasm Proteins - genetics | Protein Kinase Inhibitors - pharmacokinetics | Antimalarials - pharmacokinetics | Blood-Brain Barrier - drug effects | Flavonoids - pharmacokinetics | Mice, Knockout | Muscle Relaxants, Central - pharmacokinetics | Algorithms | Animals | ATP-Binding Cassette, Sub-Family B, Member 1 - genetics | ATP Binding Cassette Transporter, Sub-Family B | Mice | Kinetics | Mitoxantrone - pharmacokinetics
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4. Full Text Separating host and microbiome contributions to drug pharmacokinetics and toxicity
by Zimmermann, Michael and Zimmermann-Kogadeeva, Maria and Wegmann, Rebekka and Goodman, Andrew L
Science (American Association for the Advancement of Science), ISSN 0036-8075, 02/2019, Volume 363, Issue 6427, p. 600
Science & Technology - Other Topics | Multidisciplinary Sciences | Science & Technology | Bromodeoxyuridine - analogs & derivatives | Animals | Bacteroides thetaiotaomicron - enzymology | Biotransformation | Bromodeoxyuridine - pharmacokinetics | Gastrointestinal Microbiome | Germ-Free Life | Biological Availability | Bromodeoxyuridine - toxicity | Mice | Clonazepam - pharmacokinetics | Bacteroides thetaiotaomicron - genetics | Drug metabolism | Pharmacokinetics | Analysis | Drugs | Transformation | Animal models | Physiological effects | Toxicity | Health services | Microbiomes | Microorganisms | Microbiota | Absorption | Metabolites | Antidepressants | Intestine | Compartments | Animal tissues | Genetics | Biocompatibility | Oxidation | Intestinal microflora | Xenobiotics | Digestive tract | Food | Enzymes | Gnotobiotics | Effectiveness | Computer simulation | Digestive system | Exposure | Pharmacology | Bioavailability | Clonazepam | Metabolism | Conversion | Benzodiazepines | Organic chemistry | Computer applications | Nucleosides | In vivo methods and tests | Kinetics | Variation | Nucleoside analogs
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5. Full Text Similarity of Bisphenol A Pharmacokinetics in Rhesus Monkeys and Mice: Relevance for Human Exposure
by Julia A. Taylor and Frederick S. vom Saal and Wade V. Welshons and Bertram Drury and George Rottinghaus and Patricia A. Hunt and Pierre-Louis Toutain and Céline M. Laffont and Catherine A. VandeVoort
Environmental health perspectives, ISSN 0091-6765, 4/2011, Volume 119, Issue 4, pp. 422 - 430
Business publications audits | Reviews | Bisphenols | Rodents | Oral administration | Administered dose | Adults | Mice | Dosage | Female animals | Human resources | Endocrine disruption | Bisphenol A | Xenobiotic metabolism | Biomonitoring | Pharmacokinetics | Public, Environmental & Occupational Health | Environmental Sciences & Ecology | Toxicology | Life Sciences & Biomedicine | Science & Technology | Environmental Sciences | Public health. Hygiene-occupational medicine | Public health. Hygiene | Various organic compounds | Environment. Living conditions | Biological and medical sciences | Medical sciences | Chemical and industrial products toxicology. Toxic occupational diseases | Endocrine Disruptors - metabolism | Benzhydryl Compounds | Species Specificity | Humans | Liver - metabolism | Endocrine Disruptors - blood | Macaca mulatta | Environmental Exposure - analysis | Environmental Pollutants - metabolism | Phenols - metabolism | Environmental Pollutants - blood | Animals | Phenols - blood | Environmental Exposure - statistics & numerical data | Usage | Bisphenol-A | Primates | Physiological aspects | Research | Health aspects | Biological monitoring | Human | Cadmium | Monkeys | Females | Serums | Index Medicus | Life Sciences | pharmacokinetics | bisphenol A | biomonitoring | Review | xenobiotic metabolism | endocrine disruption
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6. Full Text Relevance of UDP-glucuronosyltransferase polymorphisms for drug dosing: A quantitative systematic review
by Stingl, J.C and Bartels, H and Viviani, R and Lehmann, M.L and Brockmöller, J
Pharmacology & therapeutics (Oxford), ISSN 0163-7258, 01/2014, Volume 141, Issue 1, pp. 92 - 116
Drug metabolism | UDP-glucuronosyltransferases | Pharmacogenetics | Pharmacogenetics-based dose adjustments | UGT1A1 | Polymorphism | Life Sciences & Biomedicine | Pharmacology & Pharmacy | Science & Technology | Biological and medical sciences | Medical sciences | General pharmacology | Pharmacology. Drug treatments | Pharmacokinetics. Pharmacogenetics. Drug-receptor interactions | Psychotropic Drugs - pharmacokinetics | Humans | Analgesics - metabolism | Analgesics - pharmacokinetics | Antihypertensive Agents - metabolism | Antihypertensive Agents - pharmacokinetics | Uridine Diphosphate - metabolism | Polymorphism, Genetic | Antineoplastic Agents - metabolism | Glucuronosyltransferase - genetics | Pharmaceutical Preparations - metabolism | Glucuronosyltransferase - metabolism | Anti-HIV Agents - pharmacokinetics | Antineoplastic Agents - pharmacokinetics | Psychotropic Drugs - metabolism | Anti-HIV Agents - metabolism | Pharmaceutical Preparations - administration & dosage | Pharmacokinetics | Physiological aspects | Xenobiotics | Index Medicus
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7. Full Text Metabolism and pharmacokinetics of pharmaceuticals in cats (Felix sylvestris catus) and implications for the risk assessment of feed additives and contaminants
by Lautz, L.S and Jeddi, M.Z and Girolami, F and Nebbia, C and Dorne, J.L.C.M
Toxicology letters, ISSN 0378-4274, 03/2021, Volume 338, pp. 114 - 127
Uncertainty factor | Chemical risk assessment | Feed additives | Cats | Contaminants | Rats | Pharmacokinetics | Life Sciences & Biomedicine | Toxicology | Science & Technology | Uncertainty | Xenobiotics - administration & dosage | Metabolic Detoxication, Phase II | Risk Assessment | Species Specificity | Food Contamination | Cytochrome P-450 Enzyme System - metabolism | Substrate Specificity | Animal Feed - toxicity | Xenobiotics - toxicity | Xenobiotics - pharmacokinetics | No-Observed-Adverse-Effect Level | Animals | Glucuronosyltransferase - metabolism | Metabolic Detoxication, Phase I | Enzymes | Animal feeding and feeds | Risk assessment | Alfentanil | Physiological aspects | Glycine | Xenobiotics | Index Medicus
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8. Full Text Anatomical, Physiological and Metabolic Changes with Gestational Age during Normal Pregnancy
: A Database for Parameters Required in Physiologically Based Pharmacokinetic Modelling
by Abduljalil, Khaled and Furness, Penny and Johnson, Trevor N and Rostami-Hodjegan, Amin and Soltani, Hora
Clinical pharmacokinetics, ISSN 0312-5963, 6/2012, Volume 51, Issue 6, pp. 365 - 396
Pharmacotherapy | Internal Medicine | Medicine & Public Health | Pharmacology/Toxicology | Pregnancy | Population-pharmacokinetics | Pharmacokinetics | Pharmacokinetic- modelling | Life Sciences & Biomedicine | Pharmacology & Pharmacy | Science & Technology | Biological and medical sciences | Medical sciences | General pharmacology | Pharmacology. Drug treatments | Pharmacokinetics. Pharmacogenetics. Drug-receptor interactions | Inactivation, Metabolic | Body Weight | Glomerular Filtration Rate | Humans | Organ Size | Reference Values | Xenobiotics - pharmacokinetics | Gestational Age | Regional Blood Flow | Algorithms | Pregnancy - metabolism | Models, Biological | Female | Pregnancy - physiology | Databases, Factual | Demographic aspects | Physiological aspects | Reports | Models | Research | Xenobiotics | Health aspects | Index Medicus
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