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Proceedings of the National Academy of Sciences - PNAS, ISSN 1091-6490, 12/2017, Volume 114, Issue 49, pp. E10578 - E10585
Journal Article
Journal Article
Nature medicine, ISSN 1546-170X, 10/2009, Volume 15, Issue 11, pp. 1327 - 1332
Journal Article
Proceedings of the National Academy of Sciences - PNAS, ISSN 0027-8424, 1/2013, Volume 110, Issue 5, pp. 1863 - 1868
.... This polyamide demonstrates antitumor activity in a prostate tumor xenograft model with limited host toxicity. 
Cell culture techniques | RNA | DNA | DNA damage | Genes | Cytotoxicity | Heterologous transplantation | Tumors | Vehicles | Apoptosis | Minor groove binder | Small molecule transcription inhibitor | ChIP-Seq | Science & Technology - Other Topics | Multidisciplinary Sciences | Science & Technology | Prostatic Neoplasms - metabolism | Transcription, Genetic - drug effects | Humans | Imidazoles - chemistry | Immunoblotting | Male | RNA Polymerase II - metabolism | Protein Subunits - metabolism | Antineoplastic Agents - metabolism | Dose-Response Relationship, Drug | Time Factors | Antineoplastic Agents - pharmacology | Prostatic Neoplasms - prevention & control | Prostatic Neoplasms - pathology | RNA Polymerase II - antagonists & inhibitors | Proteasome Inhibitors - pharmacology | Mice, Inbred C57BL | Tumor Suppressor Protein p53 - metabolism | Nylons - chemistry | Antineoplastic Agents - chemistry | Mice, SCID | Interleukin Receptor Common gamma Subunit - genetics | Nylons - pharmacology | Mice, Knockout | Interleukin Receptor Common gamma Subunit - deficiency | Xenograft Model Antitumor Assays | Animals | Signal Transduction - drug effects | Cell Line, Tumor | Pyrroles - chemistry | Mice, Inbred NOD | Mice | Protein Subunits - antagonists & inhibitors | Nylons - metabolism | Care and treatment | Polyamides | Genetic aspects | Research | Properties | Prostate cancer | RNA polymerases | Methods | Cancer | Index Medicus | Biological Sciences | minor groove binder | small molecule transcription inhibitor
Journal Article
Molecular therapy, ISSN 1525-0016, 10/2018, Volume 26, Issue 10, pp. 2476 - 2486
Journal Article
Nature communications, ISSN 2041-1723, 05/2019, Volume 10, Issue 1, pp. 2235 - 2235
Journal Article
Molecular therapy, ISSN 1525-0016, 04/2018, Volume 26, Issue 4, pp. 976 - 985
Several recent clinical trials have successfully incorporated a costimulatory domain derived from either CD28 or 4-1BB with the original CD3ζ T cell activating... 
CD28 signaling domain | 4-1BB signaling domain | chimeric antigen receptor | Genetics & Heredity | Life Sciences & Biomedicine | Biotechnology & Applied Microbiology | Medicine, Research & Experimental | Science & Technology | Research & Experimental Medicine | Humans | Middle Aged | Antineoplastic Combined Chemotherapy Protocols - adverse effects | Child, Preschool | Male | Leukemia, Lymphocytic, Chronic, B-Cell - genetics | CD28 Antigens - metabolism | Young Adult | Retroviridae - genetics | T-Lymphocytes - metabolism | Adult | Female | Child | Leukemia, Lymphocytic, Chronic, B-Cell - immunology | Receptors, Chimeric Antigen - metabolism | Disease Models, Animal | Immunotherapy, Adoptive - adverse effects | Immunotherapy, Adoptive - methods | Receptors, Antigen, T-Cell - metabolism | Tumor Necrosis Factor Receptor Superfamily, Member 9 - immunology | Mice, Transgenic | Treatment Outcome | CD28 Antigens - immunology | Combined Modality Therapy | Tumor Necrosis Factor Receptor Superfamily, Member 9 - metabolism | Genetic Vectors - genetics | Xenograft Model Antitumor Assays | Leukemia, Lymphocytic, Chronic, B-Cell - therapy | Animals | Antineoplastic Combined Chemotherapy Protocols - therapeutic use | Leukemia, Lymphocytic, Chronic, B-Cell - metabolism | Adolescent | Receptors, Chimeric Antigen - genetics | T-Lymphocytes - immunology | Aged | Receptors, Antigen, T-Cell - genetics | Index Medicus | Original
Journal Article
Macromolecular bioscience, ISSN 1616-5187, 12/2018, Volume 18, Issue 12, pp. 1800240 - n/a
Journal Article