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Journal Article
Journal Article
Gastroenterology, ISSN 0016-5085, 2008, Volume 134, Issue 5, pp. 1424 - 1435
Background & Aims: The isolation and culture of primary enteric neurons is a difficult process and yields a small number of neurons. We developed fetal and... 
Gastroenterology and Hepatology | SURVIVAL | NERVOUS-SYSTEM | SEROTONIN TRANSPORTER | SMOOTH-MUSCLE | GDNF | PATHWAY | NEUROTROPHIC FACTOR | TRANSGENIC MOUSE | RECEPTORS | GASTROENTEROLOGY & HEPATOLOGY | MICE LACKING | Immunohistochemistry | Neuroglia - transplantation | ELAV-Like Protein 4 | Proto-Oncogene Proteins c-ret - biosynthesis | Serotonin - genetics | Membrane Glycoproteins - biosynthesis | Colon - innervation | Synaptophysin - genetics | S100 Proteins - genetics | Muscle, Smooth - physiology | Neurons - metabolism | S100 Proteins - biosynthesis | Serotonin - biosynthesis | Peripherins | Muscle, Smooth - innervation | S100 Calcium Binding Protein beta Subunit | Enteric Nervous System - metabolism | Glial Cell Line-Derived Neurotrophic Factor - biosynthesis | Glial Cell Line-Derived Neurotrophic Factor - genetics | Mice, Transgenic | Xenopus Proteins | Reverse Transcriptase Polymerase Chain Reaction | Ubiquitin Thiolesterase - genetics | Blotting, Western | Nerve Growth Factors - genetics | Synaptophysin - biosynthesis | Mice | ELAV Proteins - genetics | Nestin | Colon - embryology | Gastrointestinal Motility - physiology | Neurons - cytology | Actins - genetics | RNA - genetics | tau Proteins - biosynthesis | Neuroglia - cytology | tau Proteins - genetics | Gene Expression Regulation, Developmental | Intermediate Filament Proteins - genetics | Nerve Tissue Proteins - biosynthesis | Female | Isometric Contraction - physiology | Cell Line | Actins - biosynthesis | ELAV Proteins - biosynthesis | Mice, Inbred C57BL | Enteric Nervous System - embryology | Intermediate Filament Proteins - biosynthesis | Nerve Growth Factors - biosynthesis | Nerve Tissue Proteins - genetics | Colon - surgery | Membrane Glycoproteins - genetics | Pregnancy | Animals | Neuroglia - metabolism | Ubiquitin Thiolesterase - biosynthesis | Proto-Oncogene Proteins c-ret - genetics | Polymerase chain reaction | Physiological aspects | Biological response modifiers | Neurons | differentiation | Enteric neurons | proliferation | nNOS | Immorto | Piebald
Journal Article
Nature, ISSN 0028-0836, 02/2018, Volume 554, Issue 7690, pp. 112 - 117
Many craniofacial disorders are caused by heterozygous mutations in general regulators of housekeeping cellular functions such as transcription or ribosome... 
PATHOGENESIS | CELLS | PROTEIN | ENDONUCLEASE | RNA HELICASE DDX21 | DNA | MULTIDISCIPLINARY SCIENCES | PREVENTION | TREACHER-COLLINS-SYNDROME | NEURAL CREST | P53 | Xenopus | Chromatin - metabolism | Cell Nucleolus - pathology | Embryonic Stem Cells - cytology | Mandibulofacial Dysostosis - embryology | Humans | Protein Transport - drug effects | DNA-Directed RNA Polymerases - deficiency | RNA, Ribosomal - genetics | RNA Polymerase I - antagonists & inhibitors | Mandibulofacial Dysostosis - genetics | Cell Nucleus - metabolism | Skull - pathology | Nuclear Proteins - deficiency | Cell Nucleolus - drug effects | Stress, Physiological - drug effects | Neural Crest - enzymology | Benzothiazoles - pharmacology | Phenotype | Zebrafish Proteins - deficiency | Ribosomes - genetics | Mice | DNA Damage | HeLa Cells | Embryonic Stem Cells - metabolism | RNA Helicases - metabolism | Mandibulofacial Dysostosis - pathology | Neural Crest - pathology | Ribosomal Proteins - biosynthesis | Ribosomes - metabolism | DNA, Ribosomal - metabolism | Phosphoproteins - metabolism | Zebrafish - embryology | Cell Nucleus - pathology | Cell Nucleolus - metabolism | DEAD-box RNA Helicases - deficiency | DEAD-box RNA Helicases - metabolism | Nuclear Proteins - genetics | DNA, Ribosomal - genetics | Cell Nucleolus - genetics | Ribosomal Proteins - genetics | Tumor Suppressor Protein p53 - metabolism | RNA, Ribosomal - metabolism | Nuclear Proteins - metabolism | Phosphoproteins - genetics | Organ Specificity | DEAD-box RNA Helicases - genetics | Animals | Phosphoproteins - deficiency | RNA, Ribosomal - biosynthesis | Cell Nucleus - drug effects | Naphthyridines - pharmacology | Apoptosis | Nucleolus organizer region | Genetic aspects | Gene mutations | Observations | Neural crest | Craniofacial dysostosis | Chromatin | Transcription | Genomics | p53 Protein | Genes | DNA damage | Ribosomal DNA | Disorders | Homeostasis | Biosynthesis | Genomes | DNA-directed RNA polymerase | Proteins | DNA helicase | Nucleoli | Embryogenesis | Cell activation | RNA processing | Chemical synthesis | Deoxyribonucleic acid--DNA | Anemia | rRNA | RNA polymerase | Embryonic growth stage | Polymerase | DNA biosynthesis | Craniofacial growth | Ribonucleic acids | Stem cells | Mutation | Developmental disabilities | Tumors | RNA helicase
Journal Article
Developmental Biology, ISSN 0012-1606, 08/2014, Volume 392, Issue 1, pp. 15 - 25
During the early vertebrate body plan formation, convergent extension (CE) of dorsal mesoderm and neurectoderm is coordinated by the evolutionarily conserved... 
Convergent-extension | NEDD4L | Dishevelled | PROTEIN | POLARITY | FGF | DEVELOPMENTAL BIOLOGY | GASTRULATION | CELL-MIGRATION | BRACHYURY | RHO | UBIQUITIN LIGASE NEDD4L | MESODERM INDUCTION | PCP PATHWAY | Xenopus Proteins - genetics | Humans | Embryo, Nonmammalian - metabolism | T-Box Domain Proteins - biosynthesis | Endosomal Sorting Complexes Required for Transport - genetics | rhoA GTP-Binding Protein - metabolism | Mesoderm - cytology | Ubiquitin-Protein Ligases - physiology | RNA, Messenger - biosynthesis | Gastrulation - physiology | Gene Expression Regulation, Developmental | HEK293 Cells | Nedd4 Ubiquitin Protein Ligases | Xenopus Proteins - biosynthesis | Xenopus laevis - genetics | Dishevelled Proteins | Wnt Signaling Pathway | Cell Line | Phosphoproteins - biosynthesis | Xenopus laevis - embryology | Mesoderm - embryology | Morpholinos - genetics | Gene Silencing | Phosphoproteins - genetics | Fetal Proteins - biosynthesis | T-Box Domain Proteins - genetics | Animals | Adaptor Proteins, Signal Transducing - genetics | Cell Polarity - physiology | Adaptor Proteins, Signal Transducing - biosynthesis | Ubiquitin-Protein Ligases - genetics | Body Patterning - genetics | Endosomal Sorting Complexes Required for Transport - physiology | rac1 GTP-Binding Protein - metabolism | Embryonic development | Ligases | Amphibians
Journal Article
Development, ISSN 0950-1991, 08/2001, Volume 128, Issue 16, pp. 3179 - 3188
Journal Article
Journal Article
Science, ISSN 0036-8075, 10/2001, Volume 294, Issue 5542, pp. 564 - 567
Blood vessels supply developing organs with metabolic sustenance. Here, we demonstrate a role for blood vessels as a source of developmental signals during... 
Transgenic animals | Blood vessels | Aorta | Research Articles | Pancreas | Insulin | Embryos | Endoderm | Endothelial cells | Endocrine cells | Endothelium | XENOPUS | GENE | LETHALITY | MULTIDISCIPLINARY SCIENCES | FLK-1 | ENDODERM | FLT-1 | VASCULAR ENDOTHELIUM | EXPRESSION | ENDOTHELIAL GROWTH-FACTOR | PDX-1 | Endothelium, Vascular - cytology | Culture Techniques | Vascular Endothelial Growth Factors | Pancreas - cytology | Repressor Proteins | Insulin - biosynthesis | Islets of Langerhans - cytology | Cell Differentiation | Lymphokines - biosynthesis | Insulin - genetics | Basic Helix-Loop-Helix Transcription Factors | Islets of Langerhans - blood supply | Signal Transduction | Paired Box Transcription Factors | Stomach - blood supply | Embryonic Induction | Mice, Transgenic | Endothelial Growth Factors - biosynthesis | Mice | Aorta - cytology | Aorta - physiology | Vascular Endothelial Growth Factor A | Stomach - embryology | Endoderm - physiology | Pancreas - blood supply | Stomach - metabolism | Endothelium, Vascular - physiology | Morphogenesis | Lymphokines - genetics | Gene Expression Regulation, Developmental | Islets of Langerhans - metabolism | Nerve Tissue Proteins - biosynthesis | Trans-Activators - genetics | Trans-Activators - biosynthesis | Endothelium, Vascular - embryology | Homeodomain Proteins - biosynthesis | Xenopus laevis | Aorta - embryology | PAX6 Transcription Factor | Islets of Langerhans - embryology | Nerve Tissue Proteins - genetics | Pancreas - embryology | Homeodomain Proteins - genetics | Mice, Inbred ICR | Animals | Endothelial Growth Factors - genetics | Stomach - cytology | Mesoderm - physiology | Eye Proteins | Usage | Growth | Physiological aspects | Organs (Anatomy) | Mice as laboratory animals | Metabolism | Experiments
Journal Article