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PLoS ONE, ISSN 1932-6203, 11/2013, Volume 8, Issue 11, pp. e78508 - e78508
CD4(+) T cells are essential to pathogenesis of ocular surface disease in dry eye. Two subtypes of CD4(+) T cells, Th1 and Th17 cells, function concurrently in... 
PATHOGENESIS | EXPERIMENTAL AUTOIMMUNE ENCEPHALOMYELITIS | DESICCATING STRESS | INTERFERON-GAMMA | INFLAMMATION | MULTIDISCIPLINARY SCIENCES | DISTINCT | PREVALENCE | LACRIMAL KERATOCONJUNCTIVITIS | EXPRESSION | TH17 CELLS | Receptors, CCR6 - immunology | Th1 Cells - pathology | Matrix Metalloproteinases - genetics | Lymph Nodes - pathology | Cornea - immunology | Interleukin-17 - immunology | Adoptive Transfer | Th1 Cells - immunology | Xerophthalmia - genetics | Goblet Cells - immunology | Conjunctiva - pathology | Matrix Metalloproteinases - immunology | Scopolamine Hydrobromide | Female | Cornea - pathology | Interferon-gamma - genetics | Receptors, CXCR3 - deficiency | Disease Models, Animal | Th17 Cells - pathology | Xerophthalmia - pathology | Conjunctiva - immunology | Interleukin-17 - genetics | Epithelial Cells - pathology | Receptors, CCR6 - deficiency | Lymph Nodes - immunology | Mice, Knockout | Animals | Epithelial Cells - immunology | Interferon-gamma - immunology | Receptors, CXCR3 - genetics | Receptors, CCR6 - genetics | Receptors, CXCR3 - immunology | Th17 Cells - immunology | Mice | Goblet Cells - pathology | Xerophthalmia - chemically induced | Xerophthalmia - immunology | Cell Movement | Animal models | Cornea | Pathogenesis | Epithelial cells | Trafficking | Helper cells | Lymphocytes T | Matrix metalloproteinase | Cell surface | Lymph nodes | Eye | Receptors | Lymphocytes | Rodents | Animal tissues | Metalloproteinase | Localization | Lymphatic system | Immune response | Psoriasis | Cytokines | Desiccants | Therapeutic applications | Inflammation | T cell receptors | CXCR3 protein | Conjunctiva | Chemokine receptors | CCR6 protein | Crohns disease | CD4 antigen | Immune systems | Medicine | γ-Interferon | Ligands | Eye diseases | Infiltration | Cell migration | Chemokines | Index Medicus
Journal Article
Biology of Blood and Marrow Transplantation, ISSN 1083-8791, 2010, Volume 16, Issue 10, pp. 1362 - 1369
Journal Article
PLoS ONE, ISSN 1932-6203, 09/2012, Volume 7, Issue 9, pp. e43688 - e43688
Journal Article
Journal of Immunology, ISSN 0022-1767, 11/2014, Volume 193, Issue 10, pp. 5264 - 5272
The Th1-associated chemokines CXCL9, CXCL10, and CXCL11 coordinate migration of CXCR3(+) Th1 cells. The objective of this study was to evaluate the role of the... 
OCULAR SURFACE | MATRIX METALLOPROTEINASES | ACTIVATION | INTERFERON-GAMMA | NK CELLS | TOLL-LIKE RECEPTOR | CORNEAL EPITHELIUM | IMMUNOLOGY | INFLAMMATORY CYTOKINES | LACRIMAL KERATOCONJUNCTIVITIS | T-CELLS | Chemokine CXCL11 - genetics | Antigens, Ly - genetics | NK Cell Lectin-Like Receptor Subfamily K - immunology | Homeodomain Proteins - immunology | Adoptive Transfer | Epithelium, Corneal - pathology | Xerophthalmia - genetics | T-Lymphocytes - transplantation | Conjunctiva - pathology | Gene Deletion | Chemokine CXCL10 - immunology | Female | Chemokine CXCL11 - immunology | Interferon-gamma - genetics | T-Lymphocytes - pathology | Epithelium, Corneal - immunology | Disease Models, Animal | Xerophthalmia - pathology | Conjunctiva - immunology | Membrane Proteins - genetics | Desiccation | Mice, Inbred C57BL | Gene Expression Regulation | Membrane Proteins - immunology | Chemokine CXCL9 - immunology | Immunity, Innate | NK Cell Lectin-Like Receptor Subfamily K - genetics | Chemokine CXCL9 - genetics | NK Cell Lectin-Like Receptor Subfamily B - immunology | Homeodomain Proteins - genetics | Mice, Knockout | Antibodies - pharmacology | Animals | NK Cell Lectin-Like Receptor Subfamily B - antagonists & inhibitors | Antigens, Ly - immunology | NK Cell Lectin-Like Receptor Subfamily B - genetics | Chemokine CXCL10 - genetics | Interferon-gamma - immunology | T-Lymphocytes - immunology | Mice | Xerophthalmia - immunology | Index Medicus | Abridged Index Medicus | NK cell receptor ligands | NK cells | chemokines | Dry eye
Journal Article
Journal Article
Journal Article
Journal Article
PLoS ONE, ISSN 1932-6203, 06/2013, Volume 8, Issue 6, pp. e65797 - e65797
Dry eye disease can cause ocular surface inflammation that disrupts the corneal epithelial barrier. While dry eye patients are known to have an increased risk... 
CYTOKINE PROFILES | DESICCATING STRESS | INFECTIVE KERATITIS | MULTIDISCIPLINARY SCIENCES | MOUSE MODEL | CORNEAL EPITHELIAL-CELLS | SJOGRENS-SYNDROME | MICROBIAL KERATITIS | BACTERIAL KERATITIS | HUMAN TEAR FLUID | CONJUNCTIVAL EPITHELIUM | Cornea - microbiology | Pseudomonas aeruginosa - immunology | Pulmonary Surfactant-Associated Protein D - deficiency | Gene Expression | Humans | Mice, Inbred C57BL | Cornea - immunology | Permeability | Pseudomonas Infections - chemically induced | Pulmonary Surfactant-Associated Protein D - genetics | Pulmonary Surfactant-Associated Protein D - immunology | Mice, Knockout | Pseudomonas Infections - immunology | Animals | Scopolamine Hydrobromide | Fluorescein | Pseudomonas Infections - pathology | Female | Cornea - pathology | Mice | Xerophthalmia - chemically induced | Xerophthalmia - immunology | Fluorescent Dyes | Xerophthalmia - pathology | Surface active agents | Bacteria | Pseudomonas aeruginosa | Health aspects | Risk factors | Diseases | Animal models | Cornea | Pathogenesis | Infections | D gene | Streptococcus infections | Eye | Proteins | Tearing | Inoculation | Humidity | Anesthesia | Scopolamine | Cytokines | Health risks | Protein D | Optometry | Surfactants | Patients | Studies | Pathology | Surfactant protein D | Contact lenses | Pharmacy | Eye diseases | Colonization | Index Medicus
Journal Article
Molecular Vision, ISSN 1090-0535, 04/2012, Volume 18, Issue 90-91, pp. 851 - 863
Purpose: Benzalkonium chloride (BAK), the most commonly used preservative in eye drops, is known to induce ocular irritation symptoms and dry eye in long-term... 
OCULAR SURFACE | APOPTOSIS-INDUCING FACTOR | CHANG CONJUNCTIVAL | KERATOCONJUNCTIVITIS SICCA | BIOCHEMISTRY & MOLECULAR BIOLOGY | PRESERVATIVE-FREE TAFLUPROST | SJOGRENS-SYNDROME | GLAUCOMA PATIENTS | OPHTHALMOLOGY | FLOW-CYTOMETRIC ANALYSIS | DRY EYE MODEL | INFLAMMATORY MARKERS | Cell Line | Cell Survival - drug effects | Chromatin - metabolism | Preservatives, Pharmaceutical - adverse effects | Oxidative Stress | Apoptosis - drug effects | Microscopy, Phase-Contrast | Benzalkonium Compounds - adverse effects | Epithelial Cells - drug effects | Humans | Ophthalmic Solutions - adverse effects | Cytochromes c - analysis | Mitochondria - drug effects | Xerophthalmia - drug therapy | Conjunctiva - pathology | Osmolar Concentration | Conjunctiva - drug effects | Apoptosis Inducing Factor - analysis | Cell Membrane Permeability - drug effects | Caspase 3 - analysis | Epithelial Cells - cytology | Sodium Chloride - chemistry | Xerophthalmia - pathology | Index Medicus | Oxidative stress | Chromatin | Epithelial cells | Mitochondrial permeability transition pore | Apoptosis-inducing factor | Membrane permeability | Benzalkonium chloride | Cytotoxicity | Cell membranes | BAK protein | Caspase-3 | Condensation | imaging | Atrophy | Cytochrome c | Eye | Osmotic pressure | Tears | Apoptosis | Life Sciences | Human health and pathology | Sensory Organs | Pharmaceutical sciences
Journal Article
Journal Article
Molecular Vision, ISSN 1090-0535, 10/2015, Volume 21, pp. 1210 - 1223
Purpose: The occurrence of repetitive dry eye is accompanied by inflammation. This study investigated the anti-inflammatory effects of chondrocyte-derived... 
OCULAR SURFACE | BARRIER DISRUPTION | STEM-CELLS | MEMBRANE | BIOCHEMISTRY & MOLECULAR BIOLOGY | IN-VIVO | DISEASE | CORNEAL EPITHELIAL-CELLS | OPHTHALMOLOGY | EXPRESSION | ESSENTIAL FATTY-ACIDS | CARTILAGE | Tumor Necrosis Factor-alpha - metabolism | Chondrocytes - chemistry | Humans | Tumor Necrosis Factor-alpha - genetics | Anti-Inflammatory Agents, Non-Steroidal - chemistry | Male | Xerophthalmia - genetics | Extracellular Matrix - chemistry | Anti-Inflammatory Agents, Non-Steroidal - pharmacology | Conjunctiva - metabolism | Conjunctiva - pathology | Matrix Metalloproteinase 9 - metabolism | Cornea - drug effects | Complex Mixtures - pharmacology | Matrix Metalloproteinase 9 - genetics | Xerophthalmia - therapy | Injections, Subcutaneous | Scopolamine Hydrobromide | Ophthalmic Solutions | Xerophthalmia - metabolism | Vascular Cell Adhesion Molecule-1 - genetics | Cornea - pathology | Disease Models, Animal | Tears - drug effects | Xerophthalmia - pathology | Signal Transduction | Matrix Metalloproteinase 2 - metabolism | Desiccation | Gene Expression Regulation | Complex Mixtures - chemistry | Cornea - metabolism | Matrix Metalloproteinase 2 - genetics | Intercellular Adhesion Molecule-1 - metabolism | Animals | Conjunctiva - drug effects | Intercellular Adhesion Molecule-1 - genetics | Tears - secretion | Mice, Inbred NOD | Mice | Vascular Cell Adhesion Molecule-1 - metabolism | Xerophthalmia - chemically induced | Index Medicus
Journal Article
Journal of Neurosurgery, ISSN 0022-3085, 11/2010, Volume 113, Issue 5, pp. 1093 - 1098
Journal Article