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1. Full Text Simultaneous extraction and depolymerization of fucoidan from Sargassum muticum in aqueous media
by Balboa, Elena M and Rivas, Sandra and Moure, Andrés and Domínguez, Herminia and Parajó, Juan Carlos
Marine Drugs, ISSN 1660-3397, 11/2013, Volume 11, Issue 11, pp. 4612 - 4627
The biomass components of the invasive seaweed Sargassum muticum were fractionated to allow their separate valorization. S. muticum (Sm) and the solid residue... 
Sargassum muticum | Alginate | Hydrothermal treatment | Fucoidan | alginate | BROWN-ALGAE | FUCANS | CHEMISTRY, MEDICINAL | SULFATE ESTERS | POLYSACCHARIDES | ANTICOAGULANT | hydrothermal treatment | LIGNOCELLULOSIC MATERIALS | fucoidan | WATER | Fucose - chemistry | Antioxidants - chemistry | Galactose - pharmacology | Freeze Drying - methods | Glucose - pharmacology | Antioxidants - pharmacology | Xylose - chemistry | Polysaccharides - pharmacology | Galactose - chemistry | Sargassum - chemistry | Glucose - chemistry | Water - chemistry | Polysaccharides - chemistry | Fucose - pharmacology | Mannose - pharmacology | Seaweed - chemistry | Mannose - chemistry | Xylose - pharmacology
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2. Full Text Hydroxyl distribution in sugar structure and its contributory role in the inhibition of Stachybotrys microspora β-glucosidase (bglG)
by Saibi, Walid and Gargouri, Ali
Carbohydrate Research, ISSN 0008-6215, 09/2011, Volume 346, Issue 13, pp. 1848 - 1854
is a filamentous fungus that produces various β-glucosidases, of which two have already been characterized. The present study reports on the production of a... 
d-Glucose | β-Glucosidase | Inhibition efficiency | Inhibition | Hydroxyl-group contribution | Stachybotrysmicrospora | D-Glucose | Stachybotrys microspora | GLYCOSIDASE | BIOCHEMISTRY & MOLECULAR BIOLOGY | PHENOTYPE | CHEMISTRY, ORGANIC | DRIED BLOOD SPOTS | CELLULASE | beta-Glucosidase | CHEMISTRY, APPLIED | STRAIN | Galactose - pharmacology | Fungal Proteins - antagonists & inhibitors | Structure-Activity Relationship | Xylose - chemistry | Maltose - chemistry | beta-Glucosidase - antagonists & inhibitors | Cellobiose - pharmacology | Fructose - pharmacology | Deoxyglucose - pharmacology | Enzyme Inhibitors - chemistry | beta-Glucosidase - metabolism | Mannose - chemistry | Enzyme Inhibitors - pharmacology | Sorbitol - chemistry | Glucose - pharmacology | Deoxyglucose - chemistry | Galactose - chemistry | Cellobiose - chemistry | Maltose - pharmacology | Glucose - chemistry | Mannose - pharmacology | Stachybotrys - enzymology | Fructose - chemistry | Sorbitol - pharmacology | Fungal Proteins - metabolism | Xylose - pharmacology
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3. Full Text The influence of chemical chaperones on enzymatic activity under thermal and chemical stresses: Common features and variation among diverse chemical families
by Levy-Sakin, Michal and Berger, Or and Feibish, Nir and Sharon, Noa and Schnaider, Lee and Shmul, Guy and Amir, Yaniv and Buzhansky, Ludmila and Gazit, Ehud
PLoS ONE, ISSN 1932-6203, 02/2014, Volume 9, Issue 2, p. e88541
Molecular and chemical chaperones are key components of the two main mechanisms that ensure structural stability and activity under environmental stresses.... 
TRIMETHYLAMINE-N-OXIDE | MOLECULAR CHAPERONES | STABILIZATION | MULTIDISCIPLINARY SCIENCES | ORGANIC OSMOLYTES | DENATURATION | LYSOZYME | AQUEOUS POLYOL SOLUTIONS | SURFACE-TENSION | AFFECT PROTEIN STABILITY | WATER | Protein Denaturation - drug effects | Temperature | Protein Structure, Secondary | Stress, Physiological | Enzyme Stability - drug effects | Molecular Chaperones - chemistry | Trypsin - metabolism | Solvents - pharmacology | Ethanol - pharmacology | Xylitol - pharmacology | Animals | Cattle | Choline - pharmacology | Polymers - pharmacology | Trypsin - chemistry | Molecular Chaperones - pharmacology | Xylose - pharmacology | Enzymes | Amino acids | Polyols | Thermal stress | Carbohydrates | Biotechnology | Trifluoroethanol | Enzyme activity | Ethanol | Structural stability | Chaperones | Alcohols | Environmental stress | Proteins | Enzymatic activity | Physiology | Sugar | Sugars | Functional groups
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4. Full Text Stringent response factors PPX1 and PPK2 play an important role in Mycobacterium tuberculosis metabolism, biofilm formation, and sensitivity to isoniazid In Vivo
by Chuang, Yu-Min and Dutta, Noton K and Hung, Chien-Fu and Wu, T.-C and Rubin, Harvey and Karakousis, Petros C
Antimicrobial Agents and Chemotherapy, ISSN 0066-4804, 11/2016, Volume 60, Issue 11, pp. 6460 - 6470
Mycobacterium tuberculosis remains a global health threat largely due to the lengthy duration of curative antibiotic treatment, contributing to medical... 
INORGANIC POLYPHOSPHATE | STOCHASTIC INDUCTION | PERSISTER CELLS | PSEUDOMONAS-AERUGINOSA | GROWTH | POLYPHOSPHATE KINASE | MICROBIOLOGY | PHARMACOLOGY & PHARMACY | INFECTION | DRUG-RESISTANCE | ANTIBIOTIC TOLERANCE | EXPRESSION | Tuberculosis, Multidrug-Resistant - immunology | Isoniazid - pharmacology | Phosphotransferases (Phosphate Group Acceptor) - genetics | Biofilms - growth & development | Glycerophosphates - metabolism | Clofazimine - pharmacology | Mycobacterium tuberculosis - drug effects | Vaccines, DNA - administration & dosage | Phosphotransferases (Phosphate Group Acceptor) - deficiency | Tuberculosis, Multidrug-Resistant - microbiology | Tuberculosis, Multidrug-Resistant - prevention & control | Acid Anhydride Hydrolases - genetics | Xylose - analogs & derivatives | Drug Resistance, Bacterial - genetics | Disease Models, Animal | Acid Anhydride Hydrolases - deficiency | Biofilms - drug effects | Gene Expression | Xylose - metabolism | Isoenzymes - genetics | Tuberculosis Vaccines - administration & dosage | Antitubercular Agents - pharmacology | Naphthoquinones - pharmacology | Isoenzymes - deficiency | Thienamycins - pharmacology | Polyphosphates - metabolism | Citric Acid Cycle - genetics | Animals | Mycobacterium tuberculosis - enzymology | Mice | Mycobacterium tuberculosis - genetics | Mycobacterium tuberculosis - growth & development | Tuberculosis, Multidrug-Resistant - drug therapy
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5. Full Text Sterol Regulatory Element-binding Protein-1 Is Regulated by Glucose at the Transcriptional Level
by Alyssa H. Hasty and Hitoshi Shimano and Naoya Yahagi and Michiyo Amemiya-Kudo and Stéphane Perrey and Tomohiro Yoshikawa and Jun-ichi Osuga and Hiroaki Okazaki and Yoshiaki Tamura and Yoko Iizuka and Futoshi Shionoiri and Ken Ohashi and Kenji Harada and Takanari Gotoda and Ryozo Nagai and Shun Ishibashi and Nobuhiro Yamada
Journal of Biological Chemistry, ISSN 0021-9258, 10/2000, Volume 275, Issue 40, pp. 31069 - 31077
In vivo studies suggest that sterol regulatory element-binding protein (SREBP)-1 plays a key role in the up-regulation of lipogenic genes in the livers of... 
SYNTHASE PROMOTER | INSULIN | LIVERS | DIFFERENTIATION FACTOR-1 | ACTIVATION | BIOCHEMISTRY & MOLECULAR BIOLOGY | POLYUNSATURATED FATTY-ACIDS | LIPOGENIC GENE-EXPRESSION | LIPOPROTEIN RECEPTOR PROMOTER | SREBP-1C MESSENGER-RNA | CULTURED-CELLS | Up-Regulation | Temperature | Transcription Factors - chemistry | Fatty Acid Synthases - metabolism | Galactose - pharmacology | Glucose - analogs & derivatives | Immunoblotting | Phosphatidylinositol 3-Kinases - antagonists & inhibitors | RNA, Messenger - metabolism | Ribonucleases - metabolism | DNA-Binding Proteins - metabolism | Dose-Response Relationship, Drug | Cell Nucleus - metabolism | Transfection | Fructosephosphates - antagonists & inhibitors | Time Factors | Fructose - pharmacology | Antimetabolites, Antineoplastic - pharmacology | Transcription, Genetic | Cell Differentiation | Cell Membrane - metabolism | Chromones - pharmacology | Genes, Reporter | CCAAT-Enhancer-Binding Proteins - metabolism | Cell Line | Colforsin - pharmacology | Liver - metabolism | Enzyme Inhibitors - pharmacology | Morpholines - pharmacology | Glucose - pharmacology | DNA-Binding Proteins - chemistry | Transcription Factors - metabolism | Blotting, Northern | Animals | Glucose - physiology | Protein Isoforms | Glucose - metabolism | Liver - cytology | Mice | Sterol Regulatory Element Binding Protein 1 | Sterol Regulatory Element Binding Protein 2 | Azaserine - pharmacology | Xylose - pharmacology
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6. Full Text Design, synthesis, cholinesterase inhibition and molecular modelling study of novel tacrine hybrids with carbohydrate derivatives
by Lopes, João Paulo Bizarro and Silva, Luana and da Costa Franarin, Gabriela and Antonio Ceschi, Marco and Seibert Lüdtke, Diogo and Ferreira Dantas, Rafael and de Salles, Cristiane Martins Cardoso and Paes Silva-Jr, Floriano and Roberto Senger, Mario and Alvim Guedes, Isabella and Emmanuel Dardenne, Laurent
Bioorganic & Medicinal Chemistry, ISSN 0968-0896, 11/2018, Volume 26, Issue 20, pp. 5566 - 5577
A series of hybrids containing tacrine linked to carbohydrate-based moieties, such as -xylose, -ribose, and -galactose derivatives, were synthesized by the... 
Xylose | Ribose | Molecular modeling | Cholinesterases | Carbohydrate | Galactose | Alzheimer | Tacrine | TORPEDO-CALIFORNICA | CHEMISTRY, MEDICINAL | ALZHEIMERS-DISEASE | BIOCHEMISTRY & MOLECULAR BIOLOGY | ACTIVE-SITE GORGE | CHEMISTRY, ORGANIC | BUTYRYLCHOLINESTERASE INHIBITORS | PREDICTION | ACETYLCHOLINESTERASE | ACID HYBRIDS | BIOLOGICAL EVALUATION | GENERATION | BINDING | Ribose - chemical synthesis | Xylose - chemical synthesis | Galactose - pharmacology | Humans | Cholinesterase Inhibitors - chemistry | Torpedo | Cholinesterase Inhibitors - chemical synthesis | Structure-Activity Relationship | Tacrine - chemical synthesis | Galactose - analogs & derivatives | Galactose - chemical synthesis | Ribose - pharmacology | Tacrine - pharmacology | Animals | Cholinesterase Inhibitors - pharmacology | Butyrylcholinesterase - metabolism | Drug Design | Ribose - analogs & derivatives | Mice | Molecular Docking Simulation | Xylose - analogs & derivatives | Tacrine - analogs & derivatives | Acetylcholinesterase - metabolism | Xylose - pharmacology | Enzymes | Analysis | Models | Derivatives (Financial instruments) | Alzheimer's disease | Sugars | Monosaccharides
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7. Full Text Analysis of the chemotactic behaviour of Leptospira using microscopic agar-drop assay
by Islam, Md. Shafiqul and Takabe, Kyosuke and Kudo, Seishi and Nakamura, Shuichi
FEMS Microbiology Letters, ISSN 0378-1097, 07/2014, Volume 356, Issue 1, pp. 39 - 44
Abstract Chemotaxis allows bacterial cells to migrate towards or away from chemical compounds. In the present study, we developed a microscopic agar-drop assay... 
agar‐drop assay | Leptospira | chemotaxis | Agar-drop assay | BACTERIA | SPIROCHAETA-AURANTIA | ESCHERICHIA-COLI | MICROBIOLOGY | VIRULENCE | FLAGELLUM | MUTANTS | CHEMORECEPTORS | MOTION | SAPROPHYTIC LEPTOSPIRA | agar-drop assay | MOTILITY | Plankton - physiology | Agar - chemistry | Leptospira - physiology | Sucrose - pharmacology | Glucose - pharmacology | Plankton - cytology | Chemotaxis | Mannitol - pharmacology | Chemotactic Factors - pharmacology | Lactose | Fructose - pharmacology | Leptospira - cytology | Xylose - pharmacology | Glucose metabolism | Analysis | Gram-negative bacteria
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8. Full Text Sea cucumber glycosides: Chemical structures, producing species and important biological properties
by Mondol, Muhammad Abdul Mojid and Shin, Hee Jae and Rahman, M. Aminur and Islam, Mohamad Tofazzal
Marine Drugs, ISSN 1660-3397, 10/2017, Volume 15, Issue 10, p. 317
Sea cucumbers belonging to echinoderm are traditionally used as tonic food in China and other Asian countries. They produce abundant biologically active... 
Cucumarioside | Glycosides | Holostane | Antifungal | Cytotoxic | Nonholostane | MINOR NONSULFATED TETRAOSIDES | CHEMISTRY, MEDICINAL | PENTACTA-QUADRANGULARIS | holostane | glycosides | cucumarioside | MARINE NATURAL-PRODUCTS | antifungal | nonholostane | CUCUMARIA-FRONDOSA | STAUROCUCUMIS-LIOUVILLEI | BOHADSCHIA-ARGUS JAEGER | MONOSULFATED TRITERPENE GLYCOSIDES | PSEUDOCOLOCHIRUS-VIOLACEUS | MENSAMARIA-INTERCEDENS LAMPERT | cytotoxic | EUPENTACTA FRAUDATRIX. STRUCTURE | Sea Cucumbers - chemistry | Hemolytic Agents - pharmacology | Triterpenes - pharmacology | Nutritive Value | Antifungal Agents - chemistry | Structure-Activity Relationship | Hemolytic Agents - isolation & purification | Triterpenes - chemistry | Antineoplastic Agents - isolation & purification | Antiviral Agents - chemistry | Glycosides - isolation & purification | Sea Cucumbers - metabolism | Antineoplastic Agents - pharmacology | Molecular Structure | Glycosides - chemistry | Antifungal Agents - pharmacology | Hemolytic Agents - chemistry | Antiviral Agents - pharmacology | Antineoplastic Agents - chemistry | Glycosides - pharmacology | Antifungal Agents - isolation & purification | Animals | Triterpenes - isolation & purification | Sea Cucumbers - classification | Antiviral Agents - isolation & purification | Biological properties | Antiviral agents | Carbohydrates | Fungicides | Toxicity | Countries | Cytotoxicity | Glucose | Biological activity | Monosaccharides | Xylose | Marine invertebrates | Species classification | Structures | Invertebrates | Species
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9. Full Text Pretreatment of empty fruit bunch from oil palm for fuel ethanol production and proposed biorefinery process
by Tan, Liping and Yu, Yongcheng and Li, Xuezhi and Zhao, Jian and Qu, Yinbo and Choo, Yuen May and Loh, Soh Kheang
Bioresource Technology, ISSN 0960-8524, 05/2013, Volume 135, pp. 275 - 282
This study evaluates the effects of some pretreatment processes to improve the enzymatic hydrolysis of oil palm empty fruit bunch (EFB) for ethanol production.... 
EFB | Biorefinery | Pretreatment | Ethanol | Enzymatic hydrolysis | SACCHARIFICATION | DILUTE-ACID | ENERGY & FUELS | ENZYMATIC-HYDROLYSIS | STEAM PRETREATMENT | AGRICULTURAL ENGINEERING | BIOTECHNOLOGY & APPLIED MICROBIOLOGY | BIOMASS | FERMENTATION | OPTIMIZATION | SPORL | CELLULOSE | WATER | Carbohydrate Metabolism - drug effects | Oxygen - pharmacology | Ethanol - metabolism | Fermentation - drug effects | Fruit - chemistry | Fruit - drug effects | Hydrogen Peroxide - pharmacology | Biofuels | Sulfites - pharmacology | Biotechnology - methods | Palm Oil | Arecaceae - drug effects | Biocatalysis - drug effects | Oxidation-Reduction - drug effects | Glucose - metabolism | Sulfuric Acids - pharmacology | Alkalies - pharmacology | Plant Oils - chemistry | Arecaceae - chemistry | Hydrolysis | Enzymes | Sulfites | Alcohol, Denatured | Alcohol | Production processes | Production data | Xylose | Refining | Palm | Ethyl alcohol | Optimization | Fruits
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10. Full Text Cyclopentyl methyl ether: A green co-solvent for the selective dehydration of lignocellulosic pentoses to furfural
by Campos Molina, M.J and Mariscal, R and Ojeda, M and López Granados, M
Bioresource Technology, ISSN 0960-8524, 12/2012, Volume 126, pp. 321 - 327
► First report on the CPME utilization for furfural production from lignocellulose. ► CPME is a green solvent, in contrast to other tested solvents. ► Study... 
Xylose | Furfural | Lignocellulose | Cynara cardunculus | Catalytic dehydration | D-XYLOSE | CONVERSION | ENERGY & FUELS | ACID-CATALYZED HYDROLYSIS | AGRICULTURAL ENGINEERING | BIOTECHNOLOGY & APPLIED MICROBIOLOGY | GLUCOSE | BIOMASS | Solvents | Temperature | Xylose - metabolism | Sodium Chloride - pharmacology | Methyl Ethers - pharmacology | Biomass | Cyclopentanes - pharmacology | Hexoses - metabolism | Ethers - pharmacology | Furaldehyde - metabolism | Lignin - metabolism | Green Chemistry Technology - methods | Cynara - metabolism | Cynara - drug effects | Methyl ether | Sugars | Monosaccharides | Aqueous solutions | Pentose | Mass ratios | Ethers | Dehydration
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11. Full Text Simultaneous saccharification and co-fermentation of dry diluted acid pretreated corn stover at high dry matter loading: Overcoming the inhibitors by non-tolerant yeast
by Zhu, Jia-Qing and Qin, Lei and Li, Wen-Chao and Li, Bing-Zhi and Zhang, Jian and Bao, Jie and Huang, Yao-Dong and Yuan, Ying-Jin
Bioresource Technology, ISSN 0960-8524, 12/2015, Volume 198, pp. 39 - 46
Dry dilute acid pretreatment (DDAP) is a promising method for lignocellulose bioconversion, although inhibitors generated during the pretreatment impede the... 
Simultaneous saccharification and co-fermentation | Xylose utilization | High solid loading | Inhibitor tolerance | Fed-batch fermentation | XYLOSE | PHENOL | ENERGY & FUELS | HIGH-TEMPERATURE | ENZYMATIC-HYDROLYSIS | SACCHAROMYCES-CEREVISIAE | ACETIC-ACID | HIGH-SOLIDS LOADINGS | BIOETHANOL PRODUCTION | MULTIPLE INHIBITORS | AGRICULTURAL ENGINEERING | BIOTECHNOLOGY & APPLIED MICROBIOLOGY | ETHANOL | Lignin | Ethanol - pharmacology | Time Factors | Bioreactors | Desiccation | Zea mays - drug effects | Saccharomyces cerevisiae - drug effects | Biomass | Fermentation | Acids - pharmacology | Solvents - pharmacology | Xylose - pharmacology | Corn | Yuan (China) | Sugars | Monosaccharides
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12. Full Text Screening of oleaginous yeast strains tolerant to lignocellulose degradation compounds
by Chen, Xi and Li, Zihui and Zhang, Xiaoxi and Hu, Fengxian and Ryu, Dewey D.Y and Bao, Jie
Applied Biochemistry and Biotechnology, ISSN 0273-2289, 12/2009, Volume 159, Issue 3, pp. 591 - 604
High cost of triacylglycerol lipid feedstock is the major barrier for commercial production of biodiesel. The fermentation of oleaginous yeasts for lipid... 
Screening | Triacylglycerol lipid | Trichosporon cutaneum | Lignocellulose degradation compounds | Oleaginous yeasts | BIOCHEMISTRY & MOLECULAR BIOLOGY | SACCHAROMYCES-CEREVISIAE | INHIBITION | OIL | BIOTECHNOLOGY & APPLIED MICROBIOLOGY | BIOMASS | BIODIESEL FUEL | FERMENTATION | Fermentation - drug effects | Furaldehyde - analogs & derivatives | Levulinic Acids - pharmacology | Trichosporon - drug effects | Trichosporon - metabolism | Acetic Acid - pharmacology | Benzaldehydes - pharmacology | Biofuels | Rhodotorula - drug effects | Lignin - metabolism | Rhodotorula - metabolism | Formates - pharmacology | Furaldehyde - pharmacology | Hydrolysis | Heterocyclic compounds | Formic acid | Analysis | Triglycerides | Thiophene | Acetic acid | Organic acids | Sulfuric acid | Biodegradation | Biochemistry | Yeast | Fermentation | Biodiesel fuels
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13. Full Text Improvement of multiple stress tolerance in yeast strain by sequential mutagenesis for enhanced bioethanol production
by Kumari, Rajni and Pramanik, Krishna
Journal of Bioscience and Bioengineering, ISSN 1389-1723, 12/2012, Volume 114, Issue 6, pp. 622 - 629
The present work deals with the improvement of multiple stress tolerance in a glucose–xylose co-fermenting hybrid yeast strain RPR39 by sequential mutagenesis... 
Fermentation inhibitors | Ethanol fermentation | Mutagenesis | Stress tolerance | Mutants | MUTANT | XYLOSE | ACID | THERMOTOLERANT | FOOD SCIENCE & TECHNOLOGY | ETHANOL-PRODUCTION | PICHIA-STIPITIS | SACCHAROMYCES-CEREVISIAE | BIOTECHNOLOGY & APPLIED MICROBIOLOGY | GLUCOSE | FERMENTATION | SELECTION | Fermentation - radiation effects | Saccharomyces cerevisiae - genetics | Saccharomyces cerevisiae - drug effects | Mutagenesis - drug effects | Saccharomyces cerevisiae - metabolism | Methylnitronitrosoguanidine - pharmacology | Mutagenesis - radiation effects | Ultraviolet Rays | Fermentation - genetics | Stress, Physiological - drug effects | Ethanol - supply & distribution | Xylose - metabolism | Ethanol - metabolism | Fermentation - drug effects | Saccharomyces cerevisiae - radiation effects | Stress, Physiological - genetics | Mutagenesis - genetics | Mutagens - pharmacology | Acetic Acid - pharmacology | Glucose - pharmacology | Hot Temperature | Ethanol - pharmacology | Bioreactors | Furaldehyde - pharmacology | Glucose - metabolism | Xylose - pharmacology | Acetic acid | Organic acids | Alcohols | Index Medicus
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14. Full Text Acetaldehyde production by major oral microbes
by Moritani, K and Takeshita, T and Shibata, Y and Ninomiya, T and Kiyohara, Y and Yamashita, Y
Oral Diseases, ISSN 1354-523X, 09/2015, Volume 21, Issue 6, pp. 748 - 754
Objectives To assess acetaldehyde (ACH) production by bacteria constituting the oral microbiota and the inhibitory effects of sugar alcohols on ACH production.... 
acetaldehyde | oral microbiota | upper aerodigestive tract cancer | sugar alcohol | Oral microbiota | Sugar alcohol | Upper aerodigestive tract cancer | Acetaldehyde | CAVITY | INDIGENOUS MICROBIOTA | UPPER AERODIGESTIVE TRACT | NECK-CANCER | STREPTOCOCCI | DENTISTRY, ORAL SURGERY & MEDICINE | CANCER-RISK | ETHANOL | SALIVARY ACETALDEHYDE | ALCOHOL-DRINKING | EPIDEMIOLOGY | Bacteria - metabolism | Acetaldehyde - metabolism | Humans | Middle Aged | Bacteria - drug effects | Sucrose - pharmacology | Male | Glucose - pharmacology | Sugar Alcohols - pharmacology | Bacteria - isolation & purification | Microbiota | Fructose - pharmacology | Saliva - microbiology | Adult | Bacteriological Techniques | Female | Xylose - pharmacology | Xylitol | Microbiota (Symbiotic organisms) | RNA | Analysis | Bacteria | Glucose | Chromatography | Dextrose | Body fluids | Microbiology | Aldehydes | Sugar | Dentistry
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