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Cancer Cell, ISSN 1535-6108, 02/2018, Volume 33, Issue 2, pp. 160 - 161
Current therapies for malignant peripheral nerve sheath tumors (MPNSTs) are ineffective. The study by Wu et al. in this issue of provides evidence that the... 
SCHWANN-CELLS | ONCOLOGY | YAP/TAZ | CELL BIOLOGY | Tumors | Index Medicus
Journal Article
Biomedicine and Pharmacotherapy, ISSN 0753-3322, 07/2019, Volume 115, p. 108860
EGFR tyrosine kinase inhibitors (EGFR-TKIs) improve the progression-free survival of patients with non-small cell lung cancer (NSCLC). However, most patients... 
YAP/TAZ | Gossypol | EGFR | Non-small cell lung cancer
Journal Article
Biomedicine & Pharmacotherapy, ISSN 0753-3322, 07/2019, Volume 115, pp. 108860 - 108860
EGFR tyrosine kinase inhibitors (EGFR-TKIs) improve the progression-free survival of patients with non-small cell lung cancer (NSCLC). However, most patients... 
EGFRL858R/T790M | YAP/TAZ | Gossypol | Non-small cell lung cancer
Journal Article
Science, ISSN 0036-8075, 05/2015, Volume 348, Issue 6238, pp. 1024 - 1027
Mechanical strain regulates the development, organization, and function of multicellular tissues, but mechanisms linking mechanical strain and cell-cell... 
COMPLEX | YAP/TAZ | SIGNALING-PATHWAY | ALPHA-CATENIN | MULTIDISCIPLINARY SCIENCES | GROWTH | TUMOR-SUPPRESSOR | PROLIFERATION | WNT | EXPRESSION | NEGATIVE REGULATOR | Progressions | Cellular | Regulators | Reentry | Organizations | Activation | Joining | Strain
Journal Article
Journal of Central South University (Medical Sciences), ISSN 1672-7347, 03/2018, Volume 43, Issue 3, pp. 313 - 319
Journal Article
Current Biology, ISSN 0960-9822, 05/2019, Volume 29, Issue 9, pp. R334 - R337
A new mechanism for the selection and differentiation of a single cell, based on mechanical competition with its neighbors and differential TAZ activity, is... 
YAP/TAZ | BIOCHEMISTRY & MOLECULAR BIOLOGY | GROWTH | HIPPO | CELL BIOLOGY | Medical colleges | Cell differentiation | Stem cells | Biomedical engineering
Journal Article
PLOS ONE, ISSN 1932-6203, 05/2019, Volume 14, Issue 5
We examined the impact of statins on Yes-associated Protein (YAP) localization, phosphorylation and transcriptional activity in human and mouse pancreatic... 
HIGH-FAT | INSULIN-RECEPTOR | PROTEIN-COUPLED RECEPTOR | PATHWAY | YAP/TAZ | MULTIDISCIPLINARY SCIENCES | HIPPO | MUTANT P53 | MEVALONATE | TAZ | SIGNALING SYSTEMS
Journal Article
MOLECULAR CANCER RESEARCH, ISSN 1541-7786, 08/2019, Volume 17, Issue 8, pp. 1735 - 1747
Progression of benign tumors to invasive, metastatic cancer is accompanied by the epithelial-to-mesenchymal transition (EMT), characterized by loss of the... 
SPCA2 | ADHESION | ONCOLOGY | CA2 | YAP/TAZ | SIGNALING-PATHWAY | CONTACT INHIBITION | DEGRADATION | PUMP | EXPRESSION | SECRETORY PATHWAY | CELL BIOLOGY | Index Medicus
Journal Article
Nature Cell Biology, ISSN 1465-7392, 2014, Volume 16, Issue 4, pp. 357 - 366
The YAP and TAZ mediators of the Hippo pathway ( hereafter called YAP/TAZ) promote tissue proliferation and organ growth. However, how their biological... 
ORGAN GROWTH | CHOLESTEROL | YAP/TAZ | TRANSCRIPTION | HIPPO PATHWAY | STATINS | CELL BIOLOGY | Phosphorylation - physiology | Cell Proliferation | Active Transport, Cell Nucleus - physiology | Humans | Intracellular Signaling Peptides and Proteins - metabolism | Drosophila Proteins - metabolism | Phosphoproteins - metabolism | Sterol Regulatory Element Binding Proteins - genetics | Breast Neoplasms - metabolism | Drosophila melanogaster - metabolism | RNA Interference | Tumor Suppressor Proteins - genetics | HEK293 Cells | Trans-Activators - genetics | Female | Transcription, Genetic | Hydroxymethylglutaryl-CoA Reductases, NAD-Dependent - metabolism | Nuclear Proteins - genetics | Protein-Serine-Threonine Kinases - metabolism | Signal Transduction | HCT116 Cells | Protein-Serine-Threonine Kinases - genetics | Nuclear Proteins - metabolism | Sterol Regulatory Element Binding Proteins - metabolism | Transcription Factors - genetics | Mevalonic Acid - metabolism | Polyisoprenyl Phosphates - metabolism | Transcription Factors - metabolism | Animals | Hydroxymethylglutaryl-CoA Reductase Inhibitors - pharmacology | rho GTP-Binding Proteins - metabolism | Trans-Activators - metabolism | Mice | Polyisoprenyl Phosphates - biosynthesis | Pyridines - pharmacology | RNA, Small Interfering | Drosophila Proteins - genetics | Adaptor Proteins, Signal Transducing - metabolism | Cell metabolism | Genetic research | Genetic aspects | Research | Cellular control mechanisms | Index Medicus
Journal Article
PLOS ONE, ISSN 1932-6203, 04/2018, Volume 13, Issue 4
Osteoblast differentiation is a highly regulated process that requires coordinated information from both soluble factors and the extracellular matrix. Among... 
OSTERIX | BONE-FORMATION | YAP/TAZ | ROLES | MULTIDISCIPLINARY SCIENCES | MINERALIZATION | FIBRONECTIN | EXTRACELLULAR-MATRIX | INTEGRIN RECEPTORS | SPECIFICATION | BETA
Journal Article
BMB Reports, ISSN 1976-6696, 2017, Volume 50, Issue 1, p. 1
Acquiring a selective growth advantage by breaking the proliferation barrier established by gatekeeper genes is a centrally important event in tumor formation.... 
Hippo | Wnt/β-catenin | Yap/Taz | HCC | Notch pathways
Journal Article
Biomedicine & Pharmacotherapy, ISSN 0753-3322, 06/2018, Volume 102, pp. 263 - 270
This work aims to study the roles and mechanisms of metformin in glioma cells stemness and epithelial-mesenchymal transition. Here, we found that metformin... 
Metformin | Glioma | YAP/TAZ | Hippo | CSCs | Transforming growth factors | Gliomas | Stem cells | Index Medicus
Journal Article
Journal of the American Chemical Society, ISSN 0002-7863, 09/2018, Volume 140, Issue 37, pp. 11585 - 11588
Muscle cells sense the mechanical properties of their microenvironment, and these properties can change in response to injury or disease. Hydrogels with... 
3-DIMENSIONAL HYDROGELS | STEM-CELL FATE | YAP/TAZ | CHEMISTRY | CULTURE | CHEMISTRY, MULTIDISCIPLINARY | MICROENVIRONMENTS
Journal Article
Oncotarget, ISSN 1949-2553, 02/2019, Volume 10, Issue 15, pp. 1525 - 1538
The Hippo pathway regulates cell proliferation, survival, apoptosis and differentiation. During carcinogenesis, members of the Hippo pathway are mutated to... 
Hippo pathway | Anchorage-independent growth | LATS1 kinase | YAP/TAZ | POPX2 phosphatase
Journal Article
Nature Communications, ISSN 2041-1723, 10/2015, Volume 6, Issue 1, pp. 8357 - 8357
Journal Article
Cellular Signalling, ISSN 0898-6568, 04/2017, Volume 32, pp. 93 - 103
Among the 10 Frizzled (FZD) isoforms belonging to the Class F of G protein-coupled receptors (GPCRs), FZD remains the most enigmatic. FZD shows homology to FZD... 
GNA13 | FZD | Angiogenesis | Endothelial cell | YAP/TAZ | GPCR | WNT | Index Medicus | Biological Sciences | Naturvetenskap | Biologiska vetenskaper | Natural Sciences
Journal Article
Oncotarget, ISSN 1949-2553, 12/2018, Volume 9, Issue 101, pp. 37468 - 37470
Journal Article
Genes & Diseases, ISSN 2352-3042, 06/2019
Journal Article
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