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Molecular cancer therapeutics, ISSN 1535-7163, 2/2018, Volume 17, Issue 2, pp. 443 - 454
Mounting evidence suggests that the Hippo co-activator Yes-associated protein 1 (YAP1) is a major mediator of cancer stem cell (CSC) properties, tumor... 
YAP1 | Hippo signaling | YAP1 inhibitor | EAC | radiation resistance
Journal Article
Biomedicine & Pharmacotherapy, ISSN 0753-3322, 10/2019, Volume 118
Hypoxia has been suggested to be both beneficial and harmful to the proliferation of cardiomyocytes. This controversy remains unresolved, and the underlying... 
YAP1 | Cardiomyocyte | Hypoxia | Proliferation | Sarcomere
Journal Article
Stem cells (Dayton, Ohio), ISSN 1066-5099, 5/2016, Volume 34, Issue 5, pp. 1284 - 1296
MicroRNA expression profiling in human liver progenitor cells following hepatocytic differentiation identified miR-122 and miR-194 as the microRNAs most... 
YAP1 | miR-194 | progenitor cells | differentiation | hepatocytes
Journal Article
Oncotarget, ISSN 1949-2553, 11/2017, Volume 8, Issue 55, pp. 93729 - 93740
Most malignant mesotheliomas (MPMs) frequently show activated forms of Yes-associated protein 1 (YAP1) and transcriptional co-activator with PDZ-binding motif... 
Mesothelioma | YAP1/TAZ | Migration | Invasion | RHAMM | TRANSCRIPTION | HIPPO PATHWAY | YAP | PROLIFERATION | RECEPTORS CD44 | TAZ | CELL BIOLOGY | BREAST-CANCER CELLS | ORGAN SIZE | invasion | YAP/TAZ | migration | mesothelioma
Journal Article
Oncotarget, ISSN 1949-2553, 03/2019, Volume 10, Issue 20, pp. 1874 - 1886
Lung cancer is the leading cause of cancer mortality in the United States, with an overall five-year survival rate of ~16%. Non-small cell lung cancer (NSCLC)... 
Journal Article
by Lee, BS and Park, DI and Lee, DH and Lee, JE and Yeo, MK and Park, YH and Lim, DS and Choi, W and Yoo, G and Kim, HB and Kang, D and Moon, JY and Jung, SS and Kim, JO and Cho, SY and Park, HS and Chung, C
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, ISSN 0006-291X, 09/2017, Volume 491, Issue 2, pp. 493 - 499
Developments of EGFR-TKI and immunotherapy targeting the PD1/13D-L1 pathway are considered most important medical breakthroughs in lung cancer treatment.... 
PD-Li | YAP1 | Adenocarcinoma | SURVIVAL | TARGET | BIOPHYSICS | SIGNALING PATHWAY | ROLES | Immunotherapy | BIOCHEMISTRY & MOLECULAR BIOLOGY | CANCER | EGFR
Journal Article
Biochemical and Biophysical Research Communications, ISSN 0006-291X, 09/2019, Volume 517, Issue 2, pp. 253 - 259
Gastric cancer (GC) is a common malignant tumor, and many studies have shown that circular RNAs (circRNAs) play important roles in the progress of GC. This... 
YAP1 | KDM4A | circRNA | Gastric cancer | miR-526b | Genetic research | Growth | Stomach cancer | Cancer cells | Cancer | Index Medicus
Journal Article
Oncotarget, ISSN 1949-2553, 08/2018, Volume 9, Issue 67, pp. 32736 - 32750
Pancreatic ductal adenocarcinoma (PDAC) is a fatal malignant disease with 5-year survival rate of less than 6%. Activating mutations of ( ) are often detected... 
YAP1 | Kras | PDAC | PKCΙ | Survival
Journal Article
Journal of Cellular Biochemistry, ISSN 0730-2312, 03/2018, Volume 119, Issue 3, pp. 2492 - 2500
This study indicates a negative link between miR‐622 and YAP1 and further confirm that YAP1 is a direct target of miR‐622, suggesting that miR‐622 could be a... 
YAP1 | glioma | proliferation | miR‐622 | miR-622 | INVASION | METASTASIS | MECHANISM | BIOCHEMISTRY & MOLECULAR BIOLOGY | GROWTH | TUMOR-SUPPRESSOR | EXPRESSION | CELL BIOLOGY | Gliomas | Analysis | MicroRNA | Cell proliferation | Brain | MiRNA | Tissues | Yap1 protein | 3' Untranslated regions | Clonal deletion | Ribonucleic acids | Glioma cells | Cell cycle | Deletion | Bioinformatics | Binding sites | G1 phase | Index Medicus
Journal Article
Biochemical and Biophysical Research Communications, ISSN 0006-291X, 02/2018, Volume 496, Issue 4, pp. 1308 - 1313
Breast cancer resistance to the monoclonal erbB2/HER2 antibody trastuzumab (or herceptin) has become a significant obstacle in clinical targeted therapy of... 
YAP1 | Trastuzumab resistance | UCA1 | Breast cancer | Drug sensitivity | miR-18a | BIOPHYSICS | BIOCHEMISTRY & MOLECULAR BIOLOGY | RESISTANCE | Index Medicus
Journal Article
Histopathology, ISSN 0309-0167, 05/2019
We aimed to characterize unclassifiable sarcomas by a combined histological and molecular approach. Using RNA sequencing, we have identified in-frame fusions... 
fusion | YAP1 | EPITHELIOID HEMANGIOMA | sarcoma | KMT2A | MARKER | VIM | FOS | PATHOLOGY | CELL BIOLOGY | Index Medicus
Journal Article
Fetal and Pediatric Pathology, ISSN 1551-3815, 2019, pp. 1 - 11
Epithelioid sarcoma is a malignant mesenchymal tumor exhibiting epithelioid cytomorphology and epithelial phenotype. Its histogenesis is unknown, but its... 
YAP1 | heel tumor | Epithelioid sarcoma | infant | SMARCB1/INI1 | BIRC3
Journal Article
Autophagy, ISSN 1554-8627, 12/2014, Volume 10, Issue 12, pp. 2122 - 2142
The triple-negative breast cancer (TN BC) subtype is the most aggressive form of invasive BC. Despite intensive efforts to improve BC treatments, patients with... 
YAP1 | PDX, patient-derived xenografted tumor | Ctrl, control | TGI, tumor growth inhibition | LC3B | MAP1LC3B/LC3B, microtubule-associated protein one light chain 3 β | ATG, autophagy-related | BECN1, Beclin 1, autophagy related | YAP1, Yes-associated protein 1 | sem, standard error of mean | breast cancers | BafA1, bafilomycin A | TN BC, triple-negative breast cancer | 3-dimensional culture | IHC, immunohistochemistry | BC, breast cancer | GAPDH, glyceraldehyde-3-phosphate dehydrogenase | three-MA, 3-methyladenine | autophagy | ACTB, actin, β | EBSS, Earle's balanced salt solution | TCGA, The Cancer Genome Atlas | 3D, 3-dimensions | prognosis | OS, overall survival | 1 | i.p., intra-peritoneal | AP2A1/adaptin, adaptor-related protein complex 2, α 1 subunit | AC, adriamycin and cyclophosphamide | response to treatment | ERBB2/HER2, v-erb-b2 avian erythroblastic leukemia viral oncogene homolog 2 | HScore, histological scoring | Lum, Luminal | DFS, disease-free survival | Prognosis | Breast cancers | Response to treatment | Autophagy | STEM-CELLS | INDUCED APOPTOSIS | TARGETING AUTOPHAGY | LIGHT-CHAIN 3A | DRUG-RESISTANCE | CELL BIOLOGY | PRECLINICAL MODELS | GENE-EXPRESSION | TUMOR-SUPPRESSOR | METABOLIC STRESS | TUMORIGENESIS | Receptors, Estrogen - metabolism | Microtubule-Associated Proteins - metabolism | Humans | Receptor, ErbB-2 - metabolism | Treatment Outcome | Antineoplastic Agents - therapeutic use | Autophagy - drug effects | Triple Negative Breast Neoplasms - therapy | Receptors, Estrogen - drug effects | Animals | Triple Negative Breast Neoplasms - diagnosis | Biomarkers, Tumor - metabolism | Female | Mice | Index Medicus
Journal Article
Oncotarget, 2017, Volume 8, Issue 64, pp. 107907 - 107919
Journal Article
Journal of Crohn's and Colitis, ISSN 1873-9946, 2018, Volume 12, Issue 8, pp. 993 - 1004
Journal Article
Cancer Cell, ISSN 1535-6108, 06/2019, Volume 35, Issue 6, pp. 868 - 884.e6
Heterotypic interactions across diverse cell types can enable tumor progression and hold the potential to expand therapeutic interventions. Here, combined... 
macrophages | glioblastoma | PYK2 | recruitment | SPP1 and YAP1 | PTEN | lysyl oxidase | Oxidases | Medical colleges | Gliomas | Analysis | Development and progression | Macrophages | Integrins
Journal Article
NATURE CHEMICAL BIOLOGY, ISSN 1552-4450, 08/2017, Volume 13, Issue 8, pp. 818 - 819
Peroxidases, rather than simply reducing H2O2 to water, also convey oxidation signals to proteins such as transcription factors. A new study reveals how a... 
YAP1 | YBP1 | TRANSCRIPTION FACTOR | BIOCHEMISTRY & MOLECULAR BIOLOGY | PEROXIDE-INDUCED OXIDATION
Journal Article
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