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PLoS ONE, ISSN 1932-6203, 01/2013, Volume 8, Issue 1, pp. e54261 - e54261
Cellular functions are regulated by complex networks of many different signaling pathways. The TGF beta and cAMP pathways are of particular importance in tumor... 
EPITHELIAL-MESENCHYMAL TRANSITION | GROWTH-FACTOR-BETA | STEM-CELLS | INHIBITION | HORMONE-RELATED PROTEIN | MESSENGER-RNA | BONE METASTASES | PATHWAY | MULTIDISCIPLINARY SCIENCES | BINDING PROTEIN | CAMP | Receptors, Transforming Growth Factor beta - genetics | Coculture Techniques | Humans | Smad3 Protein - metabolism | Phosphoproteins - metabolism | Breast Neoplasms - metabolism | Smad3 Protein - genetics | Mesenchymal Stromal Cells - cytology | Cyclin-Dependent Kinase Inhibitor p21 - genetics | RNA Interference | Mitogen-Activated Protein Kinase 1 - genetics | Cyclin-Dependent Kinase Inhibitor p21 - metabolism | Female | Cell Culture Techniques | Gene Expression Regulation, Neoplastic - drug effects | Phosphorylation - drug effects | Cyclic AMP - metabolism | Protein-Serine-Threonine Kinases - metabolism | Mitogen-Activated Protein Kinase 3 - genetics | Colforsin - pharmacology | Protein-Serine-Threonine Kinases - genetics | Mesenchymal Stromal Cells - metabolism | Phosphoproteins - genetics | Reverse Transcriptase Polymerase Chain Reaction | Blotting, Western | Transforming Growth Factor beta - pharmacology | Breast Neoplasms - genetics | Mitogen-Activated Protein Kinase 3 - metabolism | Receptors, Transforming Growth Factor beta - metabolism | Breast Neoplasms - pathology | Adaptor Proteins, Signal Transducing - genetics | Cell Line, Tumor | Cell Proliferation - drug effects | Adaptor Proteins, Signal Transducing - metabolism | Mitogen-Activated Protein Kinase 1 - metabolism | Cell proliferation | Phosphorylation | Mesenchyme | Smad3 protein | Metastasis | Kinases | Proteins | Signal transduction | Pathways | Cellular communication | Acetylation | Growth factors | Immunoglobulins | AMP | Cyclic AMP | Cultures | Breast cancer | Cyclic AMP response element-binding protein | Gene expression | Yes-associated protein | Signaling | Stem cells | Reagents | Biomarkers | Breast | Cancer | Index Medicus
Journal Article
Journal of Cellular and Molecular Medicine, ISSN 1582-1838, 01/2018, Volume 22, Issue 1, pp. 374 - 381
Journal Article
Oncogene, ISSN 0950-9232, 07/2015, Volume 34, Issue 31, pp. 4056 - 4068
Lung cancer is the leading cause of cancer death worldwide, with metastasis underlying majority of related deaths. Angiomotin (AMOT), a scaffold protein, has... 
YES-ASSOCIATED PROTEIN | BIOCHEMISTRY & MOLECULAR BIOLOGY | TRANSCRIPTION | HIPPO PATHWAY | YAP | PROLIFERATION | CELL BIOLOGY | BREAST-CANCER | OVEREXPRESSION | ONCOLOGY | CELL-MIGRATION | IN-VIVO | GROWTH | GENETICS & HEREDITY | Adenocarcinoma - pathology | Adenocarcinoma of Lung | Humans | Gene Expression Regulation, Neoplastic | Microfilament Proteins - physiology | Lung Neoplasms - pathology | Phosphoproteins - metabolism | Cysteine-Rich Protein 61 - metabolism | Intercellular Signaling Peptides and Proteins - physiology | Intercellular Signaling Peptides and Proteins - metabolism | Cell Transformation, Neoplastic - genetics | Membrane Proteins - physiology | HEK293 Cells | Adenocarcinoma - genetics | Membrane Proteins - metabolism | Microfilament Proteins - metabolism | Lung Neoplasms - genetics | Cysteine-Rich Protein 61 - genetics | Mice, Inbred C57BL | Cell Transformation, Neoplastic - metabolism | Disease Progression | Down-Regulation - genetics | Transcription Factors - metabolism | Animals | Mice, Nude | Cell Line, Tumor | Protein Binding | Mice | Mice, Inbred BALB C | Adaptor Proteins, Signal Transducing - metabolism | Usage | Lung cancer | Stem cells | Physiological aspects | Development and progression | Genetic aspects | Research | Drug therapy | Angiostatin | Health aspects | Signal transduction | Protein expression | Cell growth | Metastasis | Index Medicus
Journal Article
NATURE, ISSN 0028-0836, 07/2017, Volume 547, Issue 7662, pp. 179 - 179
Journal Article
Journal Article
Developmental Biology, ISSN 0012-1606, 09/2017, Volume 429, Issue 1, pp. 213 - 224
Journal Article
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 10/2018, Volume 115, Issue 42, pp. 10684 - 10689
The Hippo tumor-suppressor pathway regulates organ growth, cell proliferation, and stem cell biology. Defects in Hippo signaling and hyperactivation of its... 
APKC | RNA-binding proteins | Hippo pathway | HNRNP | Hrb27C | LOCALIZATION | hnRNP | MULTIDISCIPLINARY SCIENCES | DROSOPHILA HNRNPA/B HOMOLOG | aPKC | OVARIAN-CANCER | FAMILY | LUNG-CANCER | MESSENGER-RNA | YORKIE | HRP48 | SIZE-CONTROL | MELANOGASTER | RNA-Binding Proteins - genetics | Signal Transduction | Poly(A)-Binding Protein II - genetics | Heterogeneous-Nuclear Ribonucleoproteins - metabolism | Nuclear Proteins - metabolism | Drosophila Proteins - metabolism | Drosophila melanogaster - genetics | Heterogeneous-Nuclear Ribonucleoprotein Group F-H - genetics | Drosophila melanogaster - metabolism | Heterogeneous-Nuclear Ribonucleoprotein Group F-H - metabolism | Heterogeneous-Nuclear Ribonucleoproteins - genetics | Poly(A)-Binding Protein II - metabolism | Animals | Gene Expression Regulation, Developmental | Trans-Activators - genetics | Drosophila melanogaster - growth & development | Trans-Activators - metabolism | Drosophila Proteins - genetics | Nuclear Proteins - genetics | RNA-Binding Proteins - metabolism | Cell proliferation | Phosphorylation | Regulators | Protein kinase C | Downstream effects | Genes | Oocytes | Defects | Proteins | Cell growth | RNA transport | Polarity | Localization | RNA processing | Splicing | Drosophila | Organs | Ribonucleic acid--RNA | Gene expression | Progenitor cells | Suppressors | Yes-associated protein | RNA-binding protein | Stem cells | Cells (biology) | Mutation | Cancer | Index Medicus | Biological Sciences
Journal Article
Cell, ISSN 0092-8674, 2005, Volume 122, Issue 3, pp. 421 - 434
Journal Article
Journal Article
PLoS ONE, ISSN 1932-6203, 12/2016, Volume 11, Issue 12, pp. e0167080 - e0167080
S100A7 is expressed in many squamous cell carcinomas (SCCs). Our previous study revealed that S100A7 was dramatically induced in several SCC cells and... 
YES-ASSOCIATED PROTEIN | GROWTH-CONTROL | DOMAIN | MULTIDISCIPLINARY SCIENCES | TRANSCRIPTION | CONTACT INHIBITION | PROLIFERATION | PSORIASIN | DIFFERENTIATION | TAZ | ACTS | Phosphorylation | Cell Proliferation | Carcinoma, Squamous Cell - genetics | Carcinoma, Squamous Cell - metabolism | Carcinoma, Squamous Cell - pathology | Humans | Gene Expression Regulation, Neoplastic | Uterine Cervical Neoplasms - pathology | Phosphoproteins - metabolism | DNA-Binding Proteins - metabolism | S100 Proteins - genetics | Uterine Cervical Neoplasms - metabolism | Hepatocyte Growth Factor - genetics | Female | Cell Differentiation | Nuclear Proteins - genetics | Protein-Serine-Threonine Kinases - metabolism | Proto-Oncogene Proteins - metabolism | S100 Calcium Binding Protein A7 | Signal Transduction | Protein-Serine-Threonine Kinases - genetics | Nuclear Proteins - metabolism | Proto-Oncogene Proteins - genetics | S100 Proteins - metabolism | Phosphoproteins - genetics | Transcription Factors - genetics | DNA-Binding Proteins - genetics | Organ Specificity | Pharyngeal Neoplasms - metabolism | Uterine Cervical Neoplasms - genetics | Hepatocyte Growth Factor - metabolism | Transcription Factors - metabolism | Pharyngeal Neoplasms - genetics | Adaptor Proteins, Signal Transducing - genetics | Cell Line, Tumor | Protein Array Analysis | Pharyngeal Neoplasms - pathology | Adaptor Proteins, Signal Transducing - metabolism | Squamous cell carcinoma | Care and treatment | Genetic aspects | Research | Gene expression | Cell differentiation | Index Medicus | Cell culture | Laboratories | Activation | Biology | Tissue analysis | Cervix | Tissues | Kinases | Pharynx | Yes-associated protein | Studies | Proteins | Gene silencing | Cell growth | Education | Morphology | Cell adhesion | Cancer
Journal Article
Molecular Cell, ISSN 1097-2765, 2008, Volume 32, Issue 6, pp. 803 - 814
Journal Article
Journal Article