X
Search Filters
Format Format
Format Format
X
Sort by Item Count (A-Z)
Filter by Count
Journal Article (1716) 1716
Book Review (234) 234
Publication (210) 210
Book Chapter (11) 11
Conference Proceeding (2) 2
Dissertation (2) 2
Government Document (1) 1
Newspaper Article (1) 1
more...
Subjects Subjects
Subjects Subjects
X
Sort by Item Count (A-Z)
Filter by Count
yes-associated protein (1646) 1646
index medicus (1153) 1153
humans (729) 729
cancer (559) 559
animals (556) 556
hippo pathway (536) 536
yap (524) 524
cell biology (522) 522
signal transduction (498) 498
proteins (488) 488
oncology (406) 406
gene expression (392) 392
cell proliferation (377) 377
adaptor proteins, signal transducing - metabolism (364) 364
phosphoproteins - metabolism (360) 360
kinases (348) 348
biochemistry & molecular biology (343) 343
mice (342) 342
apoptosis (337) 337
transcription (299) 299
expression (293) 293
phosphorylation (288) 288
phosphoproteins - genetics (265) 265
adaptor proteins, signal transducing - genetics (261) 261
tumors (261) 261
protein-serine-threonine kinases - metabolism (248) 248
growth (247) 247
multidisciplinary sciences (243) 243
stem cells (242) 242
transcription factors (239) 239
female (238) 238
cell line, tumor (224) 224
proliferation (220) 220
transcription factors - metabolism (217) 217
research (216) 216
cell growth (215) 215
tumorigenesis (202) 202
article (189) 189
organ size control (189) 189
male (188) 188
genetic aspects (187) 187
metastasis (182) 182
activation (179) 179
tumor-suppressor (174) 174
taz (171) 171
signaling (164) 164
cell-proliferation (163) 163
analysis (159) 159
nuclear proteins - metabolism (150) 150
pathway (146) 146
genes (142) 142
localization (138) 138
medicine (135) 135
organ size (135) 135
research article (135) 135
differentiation (133) 133
cell cycle (132) 132
inhibition (130) 130
health aspects (129) 129
mutation (129) 129
transcription factors - genetics (129) 129
homeostasis (128) 128
biology (126) 126
cell migration (125) 125
gene expression regulation, neoplastic (123) 123
cells (122) 122
breast cancer (121) 121
hippo signaling pathway (121) 121
protein-serine-threonine kinases - genetics (121) 121
liver cancer (120) 120
development and progression (118) 118
immunohistochemistry (118) 118
signaling pathway (118) 118
hippo (117) 117
growth-control (116) 116
epithelial-mesenchymal transition (113) 113
science (113) 113
yap/taz (111) 111
metastases (110) 110
genetics & heredity (109) 109
medicine, research & experimental (108) 108
drosophila (105) 105
regeneration (104) 104
prognosis (103) 103
nuclear proteins - genetics (102) 102
rodents (102) 102
tumor suppressor genes (102) 102
developmental biology (101) 101
studies (101) 101
care and treatment (100) 100
hepatocellular-carcinoma (100) 100
protein binding (100) 100
contact inhibition (99) 99
liver (99) 99
middle aged (98) 98
size-control (98) 98
yap1 (98) 98
breast-cancer (97) 97
medical prognosis (97) 97
cell adhesion & migration (96) 96
more...
Language Language
Publication Date Publication Date
Click on a bar to filter by decade
Slide to change publication date range


Journal of Biological Chemistry, ISSN 0021-9258, 1768, Volume 289, Issue 19, pp. 13461 - 13474
Journal Article
Journal Article
PLoS ONE, ISSN 1932-6203, 10/2014, Volume 9, Issue 10, pp. e109811 - e109811
The extracellular environment possesses a rich milieu of biophysical and biochemical signaling cues that are simultaneously integrated by cells and influence... 
STEM-CELLS | TGF-BETA | TRABECULAR MESHWORK | MULTIDISCIPLINARY SCIENCES | SUBSTRATUM TOPOGRAPHY | EXTRACELLULAR-MATRIX | MECHANOTRANSDUCERS YAP | E-CADHERIN | MESENCHYMAL TRANSITION | NANOSCALE TOPOGRAPHY | BASEMENT-MEMBRANE | RNA, Small Interfering - genetics | Epithelial Cells - metabolism | Cadherins - metabolism | Transforming Growth Factor beta2 - metabolism | Epithelial Cells - drug effects | Humans | Intracellular Signaling Peptides and Proteins - metabolism | Phosphoproteins - antagonists & inhibitors | Phosphoproteins - metabolism | Wnt Proteins - metabolism | Cornea - drug effects | Wnt Proteins - genetics | Adaptor Proteins, Signal Transducing - antagonists & inhibitors | Cornea - cytology | HSP90 Heat-Shock Proteins - genetics | Cadherins - genetics | Epithelial Cells - cytology | Intracellular Signaling Peptides and Proteins - genetics | Intracellular Signaling Peptides and Proteins - antagonists & inhibitors | Gene Expression Regulation | Phosphoproteins - genetics | Lactams, Macrocyclic - pharmacology | beta Catenin - metabolism | beta Catenin - genetics | Benzoquinones - pharmacology | Cornea - metabolism | Mechanotransduction, Cellular | HSP90 Heat-Shock Proteins - antagonists & inhibitors | Intercellular Junctions - drug effects | Adaptor Proteins, Signal Transducing - genetics | HSP90 Heat-Shock Proteins - metabolism | Primary Cell Culture | Transforming Growth Factor beta2 - genetics | Adaptor Proteins, Signal Transducing - metabolism | Intercellular Junctions - ultrastructure | RNA, Small Interfering - metabolism | Heat shock proteins | Transforming growth factors | Veterinary colleges | Hsp90 protein | Cornea | Transcription factors | Phosphorylation | Wnt protein | Epithelial cells | Cytology | Science | Cell junctions | Intracellular signalling | Biology | Rigidity | Kinases | Veterinary medicine | E-cadherin | Cell morphology | Cell adhesion & migration | Proteins | β-catenin | Signal transduction | Immunology | Topography | Transcription activation | Extracellular matrix | Inhibition | Localization | Growth factors | Medical research | Phenotypes | Stroma | Connective tissue growth factor | Adherens junctions | Gene expression | Yes-associated protein | Cytoskeleton | Mechanotransduction | Position (location) | Heat shock | Index Medicus
Journal Article
Journal Article
Journal of Biological Chemistry, ISSN 0021-9258, 2017, Volume 292, Issue 47, pp. 19179 - 19197
Cell adhesion to the extracellular matrix or to surrounding cells plays a key role in cell proliferation and differentiation and is critical for proper tissue... 
Index Medicus | Life Sciences | Biochemistry, Molecular Biology | adhesion | cell proliferation | yes-associated protein (YAP) | integrin | Rac (Rac GTPase) | Cell Biology
Journal Article
Journal Article
Journal of Cellular and Molecular Medicine, ISSN 1582-1838, 11/2017, Volume 21, Issue 11, pp. 2663 - 2676
Malignant mesothelioma is an aggressive cancer that is resistant to current therapy. The poor prognosis of mesothelioma has been associated with elevated... 
YAP | therapeutic target | Hippo pathway | mesothelioma | MEDICINE, RESEARCH & EXPERIMENTAL | HIPPO SIGNALING CASCADE | CANCER STEM-CELLS | CELL BIOLOGY | TISSUE GROWTH-FACTOR | MELANOMA | TEAD | GENE | PATHWAY | DYSREGULATION | MUTATIONS | PROGRESSION | RNA, Small Interfering - genetics | Phosphorylation | Epithelial Cells - metabolism | Prognosis | Mesothelioma - pathology | Epithelial Cells - drug effects | Humans | Lung Neoplasms - metabolism | Gene Expression Regulation, Neoplastic | Spheroids, Cellular - pathology | Lung Neoplasms - pathology | rhoA GTP-Binding Protein - metabolism | Phosphoproteins - antagonists & inhibitors | rhoA GTP-Binding Protein - genetics | Phosphoproteins - metabolism | RNA, Messenger - metabolism | DNA-Binding Proteins - metabolism | rho-Associated Kinases - metabolism | Adaptor Proteins, Signal Transducing - antagonists & inhibitors | RNA, Messenger - antagonists & inhibitors | Antineoplastic Agents - pharmacology | Spheroids, Cellular - drug effects | 3' Untranslated Regions | Nuclear Proteins - genetics | Genes, Reporter | Lung Neoplasms - genetics | DNA-Binding Proteins - antagonists & inhibitors | Signal Transduction | RNA, Messenger - genetics | Spheroids, Cellular - metabolism | rho-Associated Kinases - genetics | Epithelial Cells - pathology | Nuclear Proteins - metabolism | Transcription Factors - antagonists & inhibitors | Mesothelioma - genetics | Phosphoproteins - genetics | Porphyrins - pharmacology | Transcription Factors - genetics | DNA-Binding Proteins - genetics | Transcription Factors - metabolism | Mesothelioma - metabolism | Nuclear Proteins - antagonists & inhibitors | Adaptor Proteins, Signal Transducing - genetics | Cell Line, Tumor | Adaptor Proteins, Signal Transducing - metabolism | RNA, Small Interfering - metabolism | Immunohistochemistry | Yuan (China) | Mesothelioma | RNA | Analysis | Biotechnology | Transcription | siRNA | Yes-associated protein | Proteins | Signaling | 3' Untranslated regions | Cell lines | Inhibition | Viability | Cancer | Index Medicus | Original
Journal Article
American Journal of Physiology - Lung Cellular and Molecular Physiology, ISSN 1040-0605, 2017, Volume 313, Issue 1, pp. L80 - L91
Exposure to cadmium (Cd) has been associated with development of chronic obstructive lung disease (COPD). The mechanisms and signaling pathways whereby Cd... 
Vimentin | Cadmium | Phosphorylation | Chronic obstructive lung disease | Fibrosis | LUNG FIBROSIS | APOPTOSIS | PHYSIOLOGY | BRONCHIAL EPITHELIAL-CELLS | PROTEIN-KINASE | TISSUE | vimentin | FIBROBLASTS | OBSTRUCTIVE PULMONARY-DISEASE | AIR-POLLUTION | RESPIRATORY SYSTEM | EMPHYSEMA | cadmium | fibrosis | chronic obstructive lung disease | phosphorylation | COPD | Gene Silencing - drug effects | Vimentin - metabolism | Humans | Actins - metabolism | Extracellular Matrix - metabolism | Phosphoproteins - metabolism | CDC2 Protein Kinase - metabolism | Cadmium - adverse effects | Myofibroblasts - metabolism | Cell Nucleus - metabolism | Protein Kinase C - metabolism | Phosphorylation - drug effects | Myofibroblasts - pathology | Extracellular Matrix - drug effects | Mice, Inbred C57BL | Bronchioles - pathology | Myofibroblasts - drug effects | Phosphoserine - metabolism | Mice, Knockout | Collagen - metabolism | Animals | Cell Differentiation - drug effects | Models, Biological | Protein Kinase Inhibitors - pharmacology | Adaptor Proteins, Signal Transducing - metabolism | Cell Nucleus - drug effects | Smad Proteins - metabolism | Physiological aspects | Lung diseases, Obstructive | Health aspects | Airway (Medicine) | Cdc2 protein | Secretion | Lung diseases | Smooth muscle | AKT protein | Smad3 protein | Nuclei | Fibronectin | Proteins | Respiratory tract | Yes-associated protein | Pulmonary fibrosis | Actin | Rodents | Collagen | Smad2 protein | Obstructive lung disease | Fibroblasts | Extracellular matrix | Chronic obstructive pulmonary disease | Index Medicus
Journal Article
Nature communications, ISSN 2041-1723, 12/2019, Volume 10, Issue 1, pp. 411 - 16
Journal Article
PLoS Genetics, ISSN 1553-7390, 08/2016, Volume 12, Issue 8, pp. e1006198 - e1006198
Hippo signaling acts as a master regulatory pathway controlling growth, proliferation, and apoptosis and also ensures that variations in proliferation do not... 
YES-ASSOCIATED PROTEIN | GROWTH-CONTROL | SIGNALING PATHWAY | IN-VIVO | GENETICS & HEREDITY | CONTACT INHIBITION | NON-ONCOGENE ADDICTION | CELL-CYCLE EXIT | CHROMATIN-REMODELING COMPLEXES | TUMOR-SUPPRESSOR PATHWAY | PROMOTES APOPTOSIS | Synthetic Lethal Mutations - genetics | Neurofibromin 2 - genetics | Protein Kinases - genetics | Nucleocytoplasmic Transport Proteins - biosynthesis | Apoptosis - genetics | Mitosis - genetics | Drosophila Proteins - biosynthesis | Cyclin B - genetics | Wings, Animal - growth & development | Gene Expression Regulation, Developmental | Protein Kinases - biosynthesis | Intracellular Signaling Peptides and Proteins - genetics | Drosophila - genetics | Cell Proliferation - genetics | Signal Transduction | Protein-Serine-Threonine Kinases - genetics | Organ Size | Neurofibromin 2 - biosynthesis | Intracellular Signaling Peptides and Proteins - biosynthesis | Nucleocytoplasmic Transport Proteins - genetics | Protein-Serine-Threonine Kinases - biosynthesis | Phenotype | Animals | Nuclear Matrix-Associated Proteins - genetics | Drosophila - growth & development | Drosophila Proteins - genetics | Nuclear Matrix-Associated Proteins - biosynthesis | Genetic aspects | Cellular signal transduction | Gene expression | Observations | Mitosis | Medical research | Leukemia | Cell division | Homeostasis | Grants | Kinases | Mammals | Proteins | Insects | Feedback | Regulation | Localization | Cytoplasm | Cancer | Apoptosis | Index Medicus
Journal Article
Molecular and Cellular Biology, ISSN 0270-7306, 11/2000, Volume 20, Issue 22, pp. 8526 - 8535
Journal Article
Nature Communications, ISSN 2041-1723, 08/2014, Volume 5, Issue 1, pp. 4629 - 4629
Whether the Hippo pathway contributes to cell lineage transition under pathological conditions, especially tumorigenesis, remains largely unknown. Here we show... 
YES-ASSOCIATED PROTEIN | ORGAN SIZE | HEPATOCELLULAR-CARCINOMA | STEM-LIKE CELLS | MULTIDISCIPLINARY SCIENCES | HIPPO PATHWAY | SIZE-CONTROL | DIFFERENTIATION | CANCER | ADENOSQUAMOUS CARCINOMA | TUMOR-SUPPRESSOR PATHWAY | Protein-Serine-Threonine Kinases - deficiency | Adenocarcinoma - pathology | Carcinoma, Squamous Cell - genetics | Carcinoma, Squamous Cell - pathology | Humans | Middle Aged | Lung Neoplasms - pathology | Male | Cell Transdifferentiation - genetics | Lung Neoplasms - physiopathology | Zinc Finger E-box Binding Homeobox 2 | Trans-Activators - physiology | Repressor Proteins - physiology | Cell Transdifferentiation - physiology | Adenocarcinoma - physiopathology | Tumor Suppressor Proteins - genetics | Up-Regulation - physiology | Trans-Activators - genetics | Female | Adenocarcinoma - genetics | Phosphoproteins - physiology | Disease Models, Animal | Lung Neoplasms - genetics | Transcription Factors - physiology | Protein-Serine-Threonine Kinases - genetics | Repressor Proteins - genetics | Mice, Transgenic | Phosphoproteins - genetics | Transcription Factors - genetics | Carcinoma, Squamous Cell - physiopathology | Homeodomain Proteins - genetics | Down-Regulation - physiology | Tumor Suppressor Proteins - physiology | Adaptor Proteins, Signal Transducing - physiology | Animals | Adaptor Proteins, Signal Transducing - genetics | Cell Line, Tumor | Mice | Homeodomain Proteins - physiology | Index Medicus
Journal Article