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Journal Article
Journal Article
Pharmaceutical research, ISSN 1573-904X, 2015, Volume 32, Issue 6, pp. 2003 - 2014
.... This study tests the hypothesis that brain endothelial cell derived exosomes can deliver anticancer drug across the BBB for the treatment of brain cancer in a zebrafish (Danio rerio... 
Biochemistry, general | Biomedical Engineering | Biomedicine | blood–brain barrier | Pharmacy | Medical Law | brain cancer | drug delivery | zebrafish | Pharmacology/Toxicology | exosome | blood-brain barrier | SYSTEM | CELLS | HPLC METHOD | MODEL | CHEMISTRY, MULTIDISCIPLINARY | TRANSPORT | PHARMACOLOGY & PHARMACY | NANOVESICLES | Exosomes - metabolism | Paclitaxel - metabolism | Neoplasm Transplantation | Capillary Permeability | Paclitaxel - pharmacology | Humans | Brain Neoplasms - pathology | Doxorubicin - chemistry | Green Fluorescent Proteins - genetics | Brain Neoplasms - metabolism | Antineoplastic Agents - metabolism | Paclitaxel - chemistry | Endocytosis | Heterografts | Time Factors | Antineoplastic Agents - pharmacology | Doxorubicin - metabolism | Genes, Reporter | Disease Models, Animal | Animals, Genetically Modified | Endothelial Cells - metabolism | Brain Neoplasms - genetics | Technology, Pharmaceutical - methods | Zebrafish | Antineoplastic Agents - chemistry | Brain Neoplasms - drug therapy | Chemistry, Pharmaceutical | Blood-Brain Barrier - metabolism | Particle Size | Animals | Tumor Burden - drug effects | Green Fluorescent Proteins - biosynthesis | Cell Line, Tumor | Cell Proliferation - drug effects | Drug Delivery Systems - methods | Doxorubicin - pharmacology | Drugs | Drug delivery systems | Analysis | Brain cancer | Animal genetic engineering | Health aspects | Membrane proteins | Vehicles | Chemotherapy | Pharmacology | Blood-brain barrier
Journal Article
PloS one, ISSN 1932-6203, 2015, Volume 10, Issue 6, p. e0126378
.... Thus, in this study we determined whether CD4-1+ lymphocytes can express cytokines typical of Th cells following antigen specific stimulation, using the zebrafish (Danio rerio... 
RNA, Messenger - immunology | gamma-Globulins - administration & dosage | Zebrafish - immunology | Antibodies - chemistry | Humans | Th1-Th2 Balance | Molecular Sequence Data | CD4-Positive T-Lymphocytes - classification | Phylogeny | CD4-Positive T-Lymphocytes - pathology | CD4-Positive T-Lymphocytes - immunology | Genetic Loci - immunology | Zebrafish - classification | Mycobacterium Infections, Nontuberculous - microbiology | Zebrafish Proteins - immunology | Mycobacterium Infections, Nontuberculous - immunology | Cytokines - immunology | Adaptive Immunity | Amino Acid Sequence | CD4-Positive T-Lymphocytes - microbiology | RNA, Messenger - genetics | Models, Molecular | ZAP-70 Protein-Tyrosine Kinase - genetics | Zebrafish - genetics | Sequence Alignment | Animals | Histocompatibility Antigens Class II - immunology | Mycobacterium marinum - immunology | Mycobacterium Infections, Nontuberculous - veterinary | ZAP-70 Protein-Tyrosine Kinase - immunology | Histocompatibility Antigens Class II - genetics | Mycobacterium Infections, Nontuberculous - genetics | Zebrafish Proteins - genetics | Cytokines - biosynthesis | Immunohistochemistry | Gamma globulin | Transcription factors | Carp | Homeotherms | Cytokines | Trout | Helper cells | Organs | Antibodies | Zebrafish | Homology | Stimulation | Lymphocytes T | Adaptive immunity | ZAP-70 protein | Immunity | CD4 antigen | T-cell receptor | Globulins | Lymphocytes | Fish
Journal Article