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JOURNAL OF PHYSICAL CHEMISTRY B, ISSN 1520-6106, 10/2019, Volume 123, Issue 40, pp. 8370 - 8377
X-ray studies revealed the considerable enhancement of metal-binding properties in human hemoglobin under exposure to mild damaging factors (in the presence of... 
OXIDATION | X-RAY-ABSORPTION | CHEMISTRY, PHYSICAL | ZINC-BINDING
Journal Article
Biophysical Journal, ISSN 0006-3495, 11/2010, Volume 99, Issue 10, pp. L84 - L86
Zinc-induced aggregation of amyloid-β peptide (Aβ) is a hallmark molecular feature of Alzheimer's disease. Here we provide direct thermodynamic evidence that... 
BIOPHYSICS | ZINC-BINDING | ALZHEIMERS-DISEASE | PEPTIDE | AGGREGATION | Biophysical Letter
Journal Article
Biochemical and Biophysical Research Communications, ISSN 0006-291X, 05/2019, Volume 512, Issue 4, pp. 859 - 863
Abrogation of the hemorrhagic activity of BaP1, a PI Snake Venom Metalloproteinase (SVMP) from the venom of , was achieved by the substitution of residues in... 
Snake venom metalloproteinases | Zinc-binding motif | Hemorrhage | BaP1 | Ω Loop
Journal Article
Analytical Chemistry, ISSN 0003-2700, 03/2014, Volume 86, Issue 6, pp. 3188 - 3194
In this work, we report the application of protein-templated Ag nanoclusters as a luminescent photoswitch for the detection of metal ions. Ag nanoclusters were... 
GOLD NANOPARTICLES | HIGHLY FLUORESCENT | CHEMISTRY, ANALYTICAL | HG2 | CLUSTERS | SENSORS | ZINC-BINDING | COBALT | Usage | Sensors | Analysis | Luminescence
Journal Article
Nature Chemical Biology, ISSN 1552-4450, 03/2010, Volume 6, Issue 3, pp. 238 - 243
The broad study of histone deacetylases in chemistry, biology and medicine relies on tool compounds to derive mechanistic insights. A phylogenetic analysis of... 
DOMAIN | BIOCHEMISTRY & MOLECULAR BIOLOGY | COMPLEXES | LARGAZOLE | INHIBITORS | MAFFT | CATALYTIC-ACTIVITY | IDENTIFICATION | MULTIPLE SEQUENCE ALIGNMENT | ZINC-BINDING | HDAC7 | Biochemistry | Biomedical research | Inhibitor drugs | Molecular structure | Chemical synthesis
Journal Article
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, ISSN 0002-7863, 04/2012, Volume 134, Issue 15, pp. 6625 - 6636
Abnormal interactions of Cu and Zn ions with the amyloid beta (A beta) peptide are proposed to play an important role in the pathogenesis of Alzheimer's... 
NADPH OXIDASE | ALZHEIMER A-BETA | A-BETA-42 | AMYLOID-BETA PROTEIN | DISEASE | HIGH-AFFINITY | COPPER | BINDING SITE | ZINC-BINDING | CHEMISTRY, MULTIDISCIPLINARY | OLIGOMERS
Journal Article
Biochemical and Biophysical Research Communications, ISSN 0006-291X, 10/2019
Journal Article
CELL, ISSN 0092-8674, 11/2009, Volume 139, Issue 4, pp. 744 - 756
ClpX is a AAA+ machine that uses the energy of ATP binding and hydrolysis to unfold native proteins and translocate unfolded polypeptides into the ClpP... 
TRANSLOCATION | CONFORMATIONAL-CHANGE | SUBSTRATE-BINDING | MECHANISM | RECOGNITION | CRYSTAL-STRUCTURE | BIOCHEMISTRY & MOLECULAR BIOLOGY | CHAPERONE | ATP | PORE LOOPS | ZINC-BINDING DOMAIN | CELL BIOLOGY
Journal Article
Proteins: Structure, Function and Bioinformatics, ISSN 0887-3585, 01/2009, Volume 74, Issue 1, pp. 222 - 239
Journal Article
European Journal of Medicinal Chemistry, ISSN 0223-5234, 11/2019, Volume 182, p. 111638
Four new series of aromatic sulfamates were synthesized and investigated for the inhibition of four human (h) isoforms of zinc enzyme carbonic anhydrase (CA,... 
Carbonic anhydrase | Sulfamoylation | Aromatic sulfamates | Enzyme inhibition | Pyrazolines | Molecular docking | Zinc-binding group
Journal Article
Inorganic Chemistry, ISSN 0020-1669, 11/2013, Volume 52, Issue 21, pp. 12193 - 12206
Journal Article
ACCOUNTS OF CHEMICAL RESEARCH, ISSN 0001-4842, 07/2019, Volume 52, Issue 7, pp. 2026 - 2035
CONSPECTUS: Despite tremendous research efforts in universities and pharmaceutical companies, effective drugs are still lacking for the treatment of... 
ENCEPHALOPATHY | ALUMINUM | HUMAN BRAIN | COPPER CHELATORS | AMYLOID-BETA-PEPTIDE | IRON | ROS PRODUCTION | ZINC-BINDING | CHEMISTRY, MULTIDISCIPLINARY | DIALYSIS | AGGREGATION
Journal Article
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 02/2007, Volume 104, Issue 9, pp. 3095 - 3100
Journal Article
Angewandte Chemie International Edition, ISSN 1433-7851, 09/2017, Volume 56, Issue 39, p. n/a
Alzheimer′s DiseaseThe interaction of zinc ions with amyloid‐β peptide fragments carrying the familial Taiwanese mutation D7H was studied by A. A. Makarov et... 
solution structure | zinc binding | zinc–peptide complexes | NMR spectroscopy | Alzheimer's amyloid β-peptide
Journal Article
JOURNAL OF NEUROCHEMISTRY, ISSN 0022-3042, 01/2012, Volume 120, pp. 149 - 166
The biggest risk factor for Alzheimers disease is the process of ageing, but the mechanisms that lead to the manifestation of the disease remain to be... 
OXIDATIVE STRESS | BIOCHEMISTRY & MOLECULAR BIOLOGY | metals | COPPER-BINDING | CEREBROSPINAL-FLUID | ss-amyloid precursor protein | NEUROSCIENCES | A-BETA OLIGOMERS | CELLULAR PRION PROTEIN | TRACE-ELEMENTS | A ss dimers | ZINC-BINDING SITE | ditryosine | IRON-RESPONSIVE ELEMENT | PRECURSOR PROTEIN | Alzheimer's disease | metalloproteins | TRANSGENIC MICE
Journal Article
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 12/2010, Volume 107, Issue 51, pp. 21990 - 21995
Journal Article
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