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Journal of Immunology, ISSN 0022-1767, 09/2018, Volume 201, Issue 6, pp. 1662 - 1670
Type 1 diabetes (T1D) is most likely caused by killing of beta cells by autoreactive CD8(+) T cells. Methods to isolate and identify these cells are limited by... 
TRANSPORTER ZNT8 | TYPE-1 DIABETES PATIENTS | NOD MICE | EPITOPE | KILL BETA-CELLS | MASS CYTOMETRY | AUTOANTIGEN | MECHANISMS | IMMUNOLOGY | EXPRESSION | TETRAMERS | ZnT8 | T cell libraries | autoimmunity | Type 1 diabetes | CyTOF | CD8
Journal Article
Diabetologia, ISSN 0012-186X, 8/2010, Volume 53, Issue 8, pp. 1656 - 1668
Journal Article
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 09/2017, Volume 114, Issue 38, pp. 10196 - 10201
Identified as a major biomarker for type 1 diabetes (T1D) diagnosis, zinc transporter 8 autoantibody (ZnT8A) has shown promise for staging disease risk and... 
Autoantibody | Proteoliposome | Type 1 diabetes | Full-length ZnT8 | Plasmonic | AUTOANTIBODIES | type 1 diabetes | autoantibody | ASSAY | SLC30A8 | plasmonic | MULTIDISCIPLINARY SCIENCES | ZINC TRANSPORTER ZNT8 | proteoliposome | GOLD CHIPS | full-length ZnT8 | AUTOIMMUNE | FLUORESCENCE | EXPRESSION | Physiological aspects | Diabetes | Diagnosis | Biological markers | Biological Sciences | Physical Sciences
Journal Article
Journal of Biomolecular Structure and Dynamics, ISSN 0739-1102, 2019, pp. 1 - 15
Polymorphism rs13266634 in SLC30A8 causes abnormal synthesis, maturation and secretion of insulin, resulting in decrease in efficiency of glucose metabolism... 
docking | mutation | ZnT8 transporter | molecular dynamics | human | drug | phytochemical
Journal Article
The Journal of Physical Chemistry B, ISSN 1520-6106, 11/2018, Volume 122, Issue 43, pp. 9852 - 9859
Type-2 diabetes mellitus (T2DM) is a disease hallmarked by improper homeostasis within the islets of Langerhans of the pancreas. The most critical species... 
TRANSPORTER ZNT8 | GLUCOSE-HOMEOSTASIS | MECHANISM | BETA-CELL APOPTOSIS | MASS | CHEMISTRY, PHYSICAL | PROLIFERATION
Journal Article
Journal of Mazandaran University of Medical Sciences, ISSN 1735-9279, 08/2018, Volume 28, Issue 163, pp. 10 - 23
Journal Article
JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM, ISSN 0021-972X, 09/2019, Volume 104, Issue 9, pp. 3877 - 3892
Context: Following major surgery, postoperative hyperglycemia (POHG) is associated with suboptimal outcomes among patients with diabetes and nondiabetic... 
HEMOGLOBIN | GLYCEMIC CONTROL | MANAGEMENT | PERIOPERATIVE HYPERGLYCEMIA | GLUCOSE | ENDOCRINOLOGY & METABOLISM | ARCHITECTURE | BETA-CELL | OUTCOMES | ZINC TRANSPORTER ZNT8 | ASSOCIATION
Journal Article
Journal Article
DIABETES CARE, ISSN 0149-5992, 08/2011, Volume 34, Issue 8, pp. 1760 - 1765
OBJECTIVE-We investigated whether measuring autoantibodies against zinc transporter 8 (ZnT8A) and IA-2 beta (IA-2 beta A) may improve classification of... 
AUTOANTIBODIES | REGISTRIES | ZNT8 | CLINICAL ONSET | ENDOCRINOLOGY & METABOLISM | RISK | AUTOANTIGEN | MELLITUS | TYPE-1 | IDENTIFICATION | PROTEIN-TYROSINE-PHOSPHATASE
Journal Article
by Flannick, Jason and Thorleifsson, Gudmar and Beer, Nicola L and Jacobs, Suzanne B.R and Grarup, Niels and Burtt, Noël P and Mahajan, Anubha and Fuchsberger, Christian and Atzmon, Gil and Benediktsson, Rafn and Blangero, John and Bowden, Don W and Brandslund, Ivan and Brosnan, Julia and Burslem, Frank and Chambers, John and Cho, Yoon Shin and Christensen, Cramer and Douglas, Desirée A and Duggirala, Ravindranath and Dymek, Zachary and Farjoun, Yossi and Fennell, Timothy and Fontanillas, Pierre and Forsén, Tom and Gabriel, Stacey and Glaser, Benjamin and Gudbjartsson, Daniel F and Hanis, Craig and Hansen, Torben and Hreidarsson, Astradur B and Hveem, Kristian and Ingelsson, Erik and Isomaa, Bo and Johansson, Stefan and Jørgensen, Torben and Jørgensen, Marit Eika and Kathiresan, Sekar and Kong, Augustine and Kooner, Jaspal and Kravic, Jasmina and Laakso, Markku and Lee, Jong-Young and Lind, Lars and Lindgren, Cecilia M and Linneberg, Allan and Masson, Gisli and Meitinger, Thomas and Mohlke, Karen L and Molven, Anders and Morris, Andrew P and Potluri, Shobha and Rauramaa, Rainer and Ribel-Madsen, Rasmus and Richard, Ann-Marie and Rolph, Tim and Salomaa, Veikko and Segrè, Ayellet V and Skärstrand, Hanna and Steinthorsdottir, Valgerdur and Stringham, Heather M and Sulem, Patrick and Tai, E Shyong and Teo, Yik Ying and Teslovich, Tanya and Thorsteinsdottir, Unnur and Trimmer, Jeff K and Tuomi, Tiinamaija and Tuomilehto, Jaakko and Vaziri-Sani, Fariba and Voight, Benjamin F and Wilson, James G and Boehnke, Michael and McCarthy, Mark I and Njølstad, Pål R and Pedersen, Oluf and Groop, Leif and Cox, David R and Stefansson, Kari and Altshuler, David and Go-T2D Consortium and T2D-Genes Consortium and T2D-GENES Consortium
Nature Genetics, ISSN 1061-4036, 2014, Volume 46, Issue 4, pp. 357 - 363
Journal Article
International Journal of Molecular Sciences, ISSN 1661-6596, 02/2018, Volume 19, Issue 2, p. 476
Journal Article
Clinica Chimica Acta, ISSN 0009-8981, 11/2016, Volume 462, pp. 60 - 64
3 Screen, a new ELISA for the combined measurement of autoantibodies to GAD , to IA-2 and to ZnT8, has been developed and evaluated. In the assay serum samples... 
ZnT8 | Population screening | Autoantibodies | GAD65 | Type 1 diabetes mellitus | IA-2 | Disease prediction | GAD
Journal Article
DIABETES, ISSN 0012-1797, 05/2013, Volume 62, Issue 5, pp. 1612 - 1622
We evaluated the role of ATP-sensitive K+ (K-ATP) channels, somatostatin, and Zn2+ in the control of glucagon secretion from mouse islets. Switching from 1 to... 
INSULIN | ENDOCRINE PANCREAS | RAT | BETA-CELLS | ENDOCRINOLOGY & METABOLISM | GENE-EXPRESSION | SOMATOSTATIN RECEPTORS | SECRETION | PANCREATIC A-CELLS | ZINC TRANSPORTER ZNT8 | KNOCKOUT MICE
Journal Article
Journal of Trace Elements in Medicine and Biology, ISSN 0946-672X, 12/2017, Volume 44, pp. 116 - 124
The non-synonymous single nucleotide polymorphism (SNP) rs13266634 in human zinc transporter 8, ZnT8 (SLC30A8), leads to a R325 variant, which is associated... 
ZnT8 | Diabetes | Vesicular CDF transporters | Zinc | β-cell insulin granules | VARIANTS | MEMBRANE | BIOCHEMISTRY & MOLECULAR BIOLOGY | INSULIN-SECRETION | BETA-CELLS | RISK | ZINC TRANSPORTER ZNT8 | XENOPUS-LAEVIS OOCYTES | BIOCHEMISTRY | ENDOCRINOLOGY & METABOLISM | beta-cell insulin g